scholarly journals Recent Advances in Crosslinked Nanogel for Multimodal Imaging and Cancer Therapy

Polymers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 1902
Author(s):  
Wen Zhou ◽  
Guangzhao Yang ◽  
Xiaoyue Ni ◽  
Shanchao Diao ◽  
Chen Xie ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Gene Delivery ◽  
Multimodal Imaging ◽  
Cancer Imaging ◽  
Recent Advances ◽  
Future Direction ◽  
Cancer Theranostics ◽  
Drug And Gene Delivery

Nanomaterials have been widely applied in the field of cancer imaging and therapy. However, conventional nanoparticles including micelles and liposomes may suffer the issue of dissociation in the circulation. In contrast, crosslinked nanogels the structures of which are covalently crosslinked have better physiological stability than micelles and liposomes, making them more suitable for cancer theranostics. In this review, we summarize recent advances in crosslinked nanogels for cancer imaging and therapy. The applications of nanogels in drug and gene delivery as well as development of novel cancer therapeutic methods are first introduced, followed by the introduction of applications in optical and multimodal imaging, and imaging-guided cancer therapy. The conclusion and future direction in this field are discussed at the end of this review.

scholarly journals Recent Advances of Nanotechnology-Facilitated Bacteria-Based Drug and Gene Delivery Systems for Cancer Treatment

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 940
Author(s):  
Chaojie Zhu ◽  
Zhiheng Ji ◽  
Junkai Ma ◽  
Zhijie Ding ◽  
Jie Shen ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cancer Treatment ◽  
Delivery Systems ◽  
Cancer Targeting ◽  
Cancer Treatments ◽  
Recent Advances ◽  
Therapeutic Mechanisms ◽  
Bacterial Therapy ◽  
Targeting Ability ◽  
Drug And Gene Delivery

Cancer is one of the most devastating and ubiquitous human diseases. Conventional therapies like chemotherapy and radiotherapy are the most widely used cancer treatments. Despite the notable therapeutic improvements that these measures achieve, disappointing therapeutic outcome and cancer reoccurrence commonly following these therapies demonstrate the need for better alternatives. Among them, bacterial therapy has proven to be effective in its intrinsic cancer targeting ability and various therapeutic mechanisms that can be further bolstered by nanotechnology. In this review, we will discuss recent advances of nanotechnology-facilitated bacteria-based drug and gene delivery systems in cancer treatment. Therapeutic mechanisms of these hybrid nanoformulations are highlighted to provide an up-to-date understanding of this emerging field.

Recent advances in carbon based nanosystems for cancer theranostics

2017 ◽  
Vol 5 (5) ◽  
pp. 901-952 ◽  
Author(s):  
Shine Augustine ◽  
Jay Singh ◽  
Manish Srivastava ◽  
Monica Sharma ◽  
Asmita Das ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Imaging ◽  
Carbon Allotrope ◽  
Recent Advances ◽  
Different Types ◽  
Cancer Theranostics ◽  
Carbon Based

This review deals with four different types of carbon allotrope based nanosystems and summarizes the results of recent studies that are likely to have applications in cancer theranostics. We discuss the applications of these nanosystems for cancer imaging, drug delivery, hyperthermia, and PDT/TA/PA.

scholarly journals Cancer Theranostics: A Novel Top-Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging-Guided Cancer Therapy (Adv. Mater. 36/2018)

2018 ◽  
Vol 30 (36) ◽  
pp. 1870268 ◽  
Author(s):  
Xiaoyuan Ji ◽  
Na Kong ◽  
Junqing Wang ◽  
Wenliang Li ◽  
Yuling Xiao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Multimodal Imaging ◽  
Top Down ◽  
Cancer Theranostics

scholarly journals Targeted Drug and Gene Delivery Systems for Lung Cancer Therapy

2009 ◽  
Vol 15 (23) ◽  
pp. 7299-7308 ◽  
Author(s):  
S. Sundaram ◽  
R. Trivedi ◽  
C. Durairaj ◽  
R. Ramesh ◽  
B. K. Ambati ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Gene Delivery ◽  
Delivery Systems ◽  
Lung Cancer Therapy ◽  
Targeted Drug ◽  
Drug And Gene Delivery

scholarly journals Nano-engineered delivery systems for cancer imaging and therapy: Recent advances, future direction and patent evaluation

2019 ◽  
Vol 24 (2) ◽  
pp. 462-491 ◽  
Author(s):  
Ghazal Nabil ◽  
Ketki Bhise ◽  
Samaresh Sau ◽  
Mohamed Atef ◽  
Hossny A. El-Banna ◽  
...  
Keyword(s):  
Cancer Imaging ◽  
Delivery Systems ◽  
Recent Advances ◽  
Patent Evaluation ◽  
Future Direction

scholarly journals Efficient drug and gene delivery to liver fibrosis: rationale, recent advances, and perspectives

2020 ◽  
Vol 10 (7) ◽  
pp. 1279-1293 ◽  
Author(s):  
Somayeh Mahdinloo ◽  
Seyed Hossein Kiaie ◽  
Ala Amiri ◽  
Salar Hemmati ◽  
Hadi Valizadeh ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Gene Delivery ◽  
Recent Advances ◽  
Drug And Gene Delivery

scholarly journals Mesoporous Silica Nanomaterials: Versatile Nanocarriers for Cancer Theranostics and Drug and Gene Delivery

Pharmaceutics ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 77 ◽  
Author(s):  
Samuel Kesse ◽  
Kofi Boakye-Yiadom ◽  
Belynda Ochete ◽  
Yaw Opoku-Damoah ◽  
Fahad Akhtar ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Mesoporous Silica ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Loading ◽  
Therapeutic Agents ◽  
Cancer Therapies ◽  
Functional Surface ◽  
Silica Nanomaterials ◽  
Cancer Theranostics ◽  
Drug And Gene Delivery

Mesoporous silica nanomaterials (MSNs) have made remarkable achievements and are being thought of by researchers as materials that can be used to effect great change in cancer therapies, gene delivery, and drug delivery because of their optically transparent properties, flexible size, functional surface, low toxicity profile, and very good drug loading competence. Mesoporous silica nanoparticles (MSNPs) show a very high loading capacity for therapeutic agents. It is well known that cancer is one of the most severe known medical conditions, characterized by cells that grow and spread rapidly. Thus, curtailing cancer is one of the greatest current challenges for scientists. Nanotechnology is an evolving field of study, encompassing medicine, engineering, and science, and it has evolved over the years with respect to cancer therapy. This review outlines the applications of mesoporous nanomaterials in the field of cancer theranostics, as well as drug and gene delivery. MSNs employed as therapeutic agents, as well as their importance and future prospects in the ensuing generation of cancer theranostics and drug and therapeutic gene delivery, are discussed herein. Thus, the use of mesoporous silica nanomaterials can be seen as using one stone to kill three birds.

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