scholarly journals Characterisation and Modelling of an Artificial Lens Capsule Mimicking Accommodation of Human Eyes

Polymers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 3916
Author(s):  
Huidong Wei ◽  
James S. Wolffsohn ◽  
Otavio Gomes de Oliveira ◽  
Leon N. Davies
Keyword(s):  
Silicone Rubber ◽  
Shape Change ◽  
Reaction Force ◽  
Mechanical Tests ◽  
Lens Capsule ◽  
Intraocular Lenses ◽  
Elastic Behaviour ◽  
Human Lens ◽  
Element Analysis ◽  
Hyper Elastic

A synthetic material of silicone rubber was used to construct an artificial lens capsule (ALC) in order to replicate the biomechanical behaviour of human lens capsule. The silicone rubber was characterised by monotonic and cyclic mechanical tests to reveal its hyper-elastic behaviour under uniaxial tension and simple shear as well as the rate independence. A hyper-elastic constitutive model was calibrated by the testing data and incorporated into finite element analysis (FEA). An experimental setup to simulate eye focusing (accommodation) of ALC was performed to validate the FEA model by evaluating the shape change and reaction force. The characterisation and modelling approach provided an insight into the intrinsic behaviour of materials, addressing the inflating pressure and effective stretch of ALC under the focusing process. The proposed methodology offers a virtual testing environment mimicking human capsules for the variability of dimension and stiffness, which will facilitate the verification of new ophthalmic prototype such as accommodating intraocular lenses (AIOLs).

scholarly journals An Artificial Lens Capsule with a Lens Radial Stretching System Mimicking Dynamic Eye Focusing

Polymers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 3552
Author(s):  
Huidong Wei ◽  
James S. Wolffsohn ◽  
Otavio Gomes de Oliveira ◽  
Leon N. Davies
Keyword(s):  
Silicone Rubber ◽  
Ex Vivo ◽  
Reaction Force ◽  
Crystalline Lens ◽  
Lens Capsule ◽  
Intraocular Lenses ◽  
Human Lens ◽  
Design Verification ◽  
Aged People ◽  
Radial Stretching

Presbyopia is a common eye disorder among aged people which is attributed to the loss of accommodation of the crystalline lens due to the increasing stiffness. One of the potential techniques to correct presbyopia involves removing the lens substance inside the capsule and replacing it with an artificial lens. The development of such devices, e.g., accommodating intraocular lenses (AIOLs), relies on the understanding of the biomechanical behaviour of the lens capsule and the essential design verification ex vivo. To mimic the eye’s dynamic focusing ability (accommodation), an artificial lens capsule (ALC), from silicone rubber accompanied by a lens radial stretching system (LRSS) was developed. The ALC was manufactured to offer a dimension and deforming behaviour replicating the human lens capsule. The LRSS was calibrated to provide a radial stretch simulating the change of diameter of capsules during accommodating process. The biomechanical function of the ALC was addressed by studying its evolution behaviour and reaction force under multiaxial stretch from the LRSS. The study highlighted the convenience of this application by performing preliminary tests on prototypes of ophthalmic devices (e.g., AIOLs) to restore accommodation.

Adhesion study of cultured human lens capsule cells on hydrophilic intraocular lenses coated with polyethylene glycol

2015 ◽  
Vol 41 (7) ◽  
pp. 1478-1483 ◽  
Author(s):  
Magda Massae Hata Viveiros ◽  
Ricardo Torres Soares ◽  
Michelle Sako Omodei ◽  
Cláudia Aparecida Rainho ◽  
Carlos Roberto Padovani ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Lens Capsule ◽  
Intraocular Lenses ◽  
Human Lens

scholarly journals P 229 Growth of human lens epithelial cells on the anterior lens capsule in vitro

1995 ◽  
Vol 35 ◽  
pp. S199
Author(s):  
J.H. Meyer ◽  
J. Schmidt ◽  
F. Eppinger ◽  
B. Flügel ◽  
K.U. Löffler ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Lens Capsule ◽  
Human Lens ◽  
Lens Epithelial Cells ◽  
Human Lens Epithelial Cells ◽  
Anterior Lens Capsule

scholarly journals Black rubber and the non-linear elastic response of scale invariant solids

2020 ◽  
Vol 2020 (9) ◽  
Author(s):  
Matteo Baggioli ◽  
Víctor Cáncer Castillo ◽  
Oriol Pujolàs
Keyword(s):  
Strain Curve ◽  
Effective Field ◽  
Elastic Response ◽  
Elastic Behaviour ◽  
Scale Invariant ◽  
Stress Strain ◽  
Nonlinear Stress ◽  
Hyper Elastic ◽  
Simple Class ◽  
Nonlinear Elastic

Abstract We discuss the nonlinear elastic response in scale invariant solids. Following previous work, we split the analysis into two basic options: according to whether scale invariance (SI) is a manifest or a spontaneously broken symmetry. In the latter case, one can employ effective field theory methods, whereas in the former we use holographic methods. We focus on a simple class of holographic models that exhibit elastic behaviour, and obtain their nonlinear stress-strain curves as well as an estimate of the elasticity bounds — the maximum possible deformation in the elastic (reversible) regime. The bounds differ substantially in the manifest or spontaneously broken SI cases, even when the same stress- strain curve is assumed in both cases. Additionally, the hyper-elastic subset of models (that allow for large deformations) is found to have stress-strain curves akin to natural rubber. The holographic instances in this category, which we dub black rubber, display richer stress- strain curves — with two different power-law regimes at different magnitudes of the strain.

scholarly journals 3D Finite Element Analysis of Rotary Instruments in Root Canal Dentine with Different Elastic Moduli

2021 ◽  
Vol 11 (6) ◽  
pp. 2547 ◽  
Author(s):  
Carlo Prati ◽  
João Paulo Mendes Tribst ◽  
Amanda Maria de Oliveira Dal Piva ◽  
Alexandre Luiz Souto Borges ◽  
Maurizio Ventre ◽  
...  
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Root Canal ◽  
Elastic Moduli ◽  
Reaction Force ◽  
Von Mises Stress ◽  
Elastic Behavior ◽  
Element Analysis ◽  
Heat Treated ◽  
Von Mises

The aim of the present investigation was to calculate the stress distribution generated in the root dentine canal during mechanical rotation of five different NiTi endodontic instruments by means of a finite element analysis (FEA). Two conventional alloy NiTi instruments F360 25/04 and F6 Skytaper 25/06, in comparison to three heat treated alloys NiTI Hyflex CM 25/04, Protaper Next 25/06 and One Curve 25/06 were considered and analyzed. The instruments’ flexibility (reaction force) and geometrical features (cross section, conicity) were previously investigated. For each instrument, dentine root canals with two different elastic moduli(18 and 42 GPa) were simulated with defined apical ratios. Ten different CAD instrument models were created and their mechanical behaviors were analyzed by a 3D-FEA. Static structural analyses were performed with a non-failure condition, since a linear elastic behavior was assumed for all components. All the instruments generated a stress area concentration in correspondence to the root canal curvature at approx. 7 mm from the apex. The maximum values were found when instruments were analyzed in the highest elastic modulus dentine canal. Strain and von Mises stress patterns showed a higher concentration in the first part of curved radius of all the instruments. Conventional Ni-Ti endodontic instruments demonstrated higher stress magnitudes, regardless of the conicity of 4% and 6%, and they showed the highest von Mises stress values in sound, as well as in mineralized dentine canals. Heat-treated endodontic instruments with higher flexibility values showed a reduced stress concentration map. Hyflex CM 25/04 displayed the lowest von Mises stress values of, respectively, 35.73 and 44.30 GPa for sound and mineralized dentine. The mechanical behavior of all rotary endodontic instruments was influenced by the different elastic moduli and by the dentine canal rigidity.

scholarly journals Preparation and properties of silicone rubber materials with foam/solid alternating multilayered structures

2021 ◽  
Author(s):  
Wenhuan Zhang ◽  
Zhaoping Deng ◽  
Hongwei Yuan ◽  
Shikai Luo ◽  
Huayin Wen ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Silicone Rubber ◽  
Cellular Structure ◽  
Cellular Structures ◽  
Compressive Property ◽  
Solid Layer ◽  
Multilayered Structures ◽  
Element Analysis ◽  
Morphology And Mechanical Properties

AbstractIn this paper, silicone rubber materials with foam/solid alternating multilayered structures were successfully constructed by combining the two methods of multilayered hot-pressing and supercritical carbon dioxide (SCCO2) foaming. The cellular morphology and mechanical properties of the foam/solid alternating multilayered silicone rubber materials were systematically studied. The results show that the growth of the cell was restrained by the solid layer, resulting in a decrease in the cell size. In addition, the introduction of the solid layer effectively improved the mechanical properties of the microcellular silicone rubber foam. The tensile strength and compressive strength of the foam/solid alternating multilayered silicone rubber materials reached 5.39 and 1.08 MPa, which are 46.1% and 237.5% of the pure silicone rubber foam, respectively. Finite element analysis (FEA) was applied and the results indicate that the strength and proportion of the solid layer played important roles in the tensile strength of the foam/solid alternating multilayered silicone rubber materials. Moreover, the small cellular structures in silicone rubber foam can provided a high supporting counterforce during compression, meaning that the microcellular structure of silicone rubber foam improved the compressive property compared to that for the large cellular structure of silicone rubber foam.

An immunoelectron microscope study of the aged human lens capsule

1992 ◽  
Vol 54 (3) ◽  
pp. 393-401 ◽  
Author(s):  
George E. Marshall ◽  
Anastasios G.P. Konstas ◽  
Nikolaos E. Bechrakis ◽  
William R. Lee
Keyword(s):  
Microscope Study ◽  
Lens Capsule ◽  
Human Lens

Optimal Design of Bi- and Multi-Stable Compliant Cellular Structures

2018 ◽  
Author(s):  
Quantian Luo ◽  
Liyong Tong
Keyword(s):  
Optimal Design ◽  
Virtual Work ◽  
Reaction Force ◽  
Nonlinear Finite Element ◽  
Cellular Structures ◽  
Stress And Strain ◽  
Principle Of Virtual Work ◽  
Stable States ◽  
Threshold Method ◽  
Element Analysis

This paper presents optimal design for nonlinear compliant cellular structures with bi- and multi-stable states via topology optimization. Based on the principle of virtual work, formulations for displacements and forces are derived and expressed in terms of stress and strain in all load steps in nonlinear finite element analysis. Optimization for compliant structures with bi-stable states is then formulated as: 1) to maximize the displacement under specified force larger than its critical one; and 2) to minimize the reaction force for the prescribed displacement larger than its critical one. Algorithms are developed using the present formulations and the moving iso-surface threshold method. Optimal design for a unit cell with bi-stable states is studied first, and then designs of multi-stable compliant cellular structures are discussed.

scholarly journals The Analysis with Finite Elements of the Elasto-plastic Behaviour of the Spinal Immobilizers - in the Case of Comminutive Fractures

2019 ◽  
Vol 57 (2) ◽  
pp. 253-264
Author(s):  
Bogdan Florin Toma ◽  
Constantin Nanu ◽  
Cezar Popescu ◽  
Razvan Vladimir Socolov ◽  
Vasile-Eduard Rosu ◽  
...  
Keyword(s):  
Theoretical Study ◽  
Initial Position ◽  
The Body ◽  
Elastic Behaviour ◽  
Element Analysis ◽  
Clinical Observations ◽  
Clinical Investigations ◽  
Extension Force ◽  
Bone Fragments ◽  
Tension State

In this paper it is presented a comparative theoretical study - performed by finite element analysis (FEA), of the tension state that appears at the level of the spine, as well as in the areas adjacent to it, under the following conditions: a) the existence of a comminutive fracture at the level of the vertebra T11; b) of the external immobilization of the body through a Lombax orthesis (LO) or of the internal immobilization of the column by means of a spinal fixator (SF); c) of performing some basic flexion or extension movements. In this study, both flexural force and extension force varied on three levels. The results of the comparative theoretical study were supplemented with the clinical observations obtained from a number of 52 patients who had suffered comminutive fractures in the T11 vertebra and who were treated - by external immobilization, in the Lombax orthesis or were surgically treated - by applying a trapped spinal fixator on the T10-T12 vertebrae. The study had demonstrated that, by immobilizing the body in the Lombax orthesis, following the application of the flexion or extension movement, the mobility of the body is low, the bone fragments move less distances by about 12% against to their displacement under the condition of immobilizing the column by a spinal fixator. Although, in the latter case, the displacements of the bone fragments are greater, the elastic behaviour of the spinal fixator determines the returning of the fragments and of the spine to the initial position as well as the distance between the vertebrae. Clinical investigations on patients treated by external immobilization of the body in the Lombax orthesis show that the values of the local kyphosis angle (LKA) are about 30% lower than the values of the same parameter obtained under the surgical treatment.

A Finite Element Analysis of the Human Temporomandibular Joint

1994 ◽  
Vol 116 (4) ◽  
pp. 401-407 ◽  
Author(s):  
J. Chen ◽  
Liangfeng Xu
Keyword(s):  
Finite Element ◽  
Temporomandibular Joint ◽  
Reaction Force ◽  
Element Model ◽  
Contact Stresses ◽  
Element Analysis ◽  
Tensile Stresses ◽  
Reaction Forces ◽  
Von Mises ◽  
Von Mises Stresses

A 2-D finite element model of the human temporomandibular joint (TMJ) has been developed to investigate the stresses and reaction forces within the joint during normal sagittal jaw closure. The mechanical parameters analyzed were maximum principal and von Mises stresses in the disk, the contact stresses on the condylar and temporal surfaces, and the condylar reactions. The model bypassed the complexity of estimating muscle forces by using measured joint motion as input. The model was evaluated by several tests. The results demonstrated that the resultant condylar reaction force was directed toward the posterior side of the eminence. The contact stresses along the condylar and temporal surfaces were not evenly distributed. Separations were found at both upper and lower boundaries. High tensile stresses were found at the upper boundaries. High tensile stresses were found at the upper boundary of the middle portion of the disk.

Sign in / Sign up

Export Citation Format

Share Document