scholarly journals The Evolution of the Cryopreservation Techniques in Reproductive Medicine—Exploring the Character of the Vitrified State Intra- and Extracellularly to Better Understand Cell Survival after Cryopreservation

2020 ◽  
Vol 1 (2) ◽  
pp. 142-157
Author(s):  
Pierre Vanderzwalmen ◽  
Fabien Ectors ◽  
Yannis Panagiotidis ◽  
Maximilian Schuff ◽  
Maximilian Murtinger ◽  
...  

Nowadays, cryopreservation of gametes and embryos is a fundamental, integral, and indispensable part of infertility treatment or fertility preservation. Cryopreservation is not only needed for the policy of single embryo transfer and cryopreservation of surplus embryos, but for deferring embryo transfer in the case of ovarian hyperstimulation syndrome, uterine pathologies, and suboptimal endometrium built-up or when preimplantation genetic testing is needed. Several current strategies in assisted reproduction technology (ART) would be inconceivable without highly efficient cryopreservation protocols. Nevertheless, cryopreservation hampered for a long time, especially in terms of low survival rates after freezing and thawing. Only the technical progress during the last decades, namely, in regard to the implementation and advancement of vitrification, leveraged its application, and thus, even allows the cryopreservation of human oocytes—a process that is far from being easy. This review aims to provide a deeper insight into the physical processes of cryopreservation and to explore the character of the vitrified state in the extra and intracellular milieu in order to demonstrate that the common denominator to all cryopreservation procedures is the establishment of an intracellular amorphous condition that hinders the likelihood of crystallization.

Muzikologija ◽  
2015 ◽  
pp. 147-157
Author(s):  
Melita Milin

The common denominator in the careers of two contemporaries and great men, citizens of Austria-Hungary - Leos Jan?cek and Sigmund Freud - was that, in spite of their status as outsiders, they managed to achieve well-deserved recognition. Both non-Germans, they had to surmount a number of obstacles in order to attain their professional goals. The Slavophile Jan?cek dreamed for a long time of success in Prague, which came at last in 1916, two years before a triumph in Vienna. Freud had serious difficulties in his academic career because of the strengthening of racial prejudices and national hatred which were especially marked at the end of the 19th century. After the dissolution of the Empire things changed for the better for the composer, whose works got an excellent reception in Austria and Germany, whereas the psychiatrist had to leave Vienna after the Anschluss.


2007 ◽  
Vol 5 ◽  
pp. 239-269 ◽  
Author(s):  
Andreea S. Calude

In Romanian, the middle marker se is employed to encode five distinct situation types: reflexive, reciprocal, (medio-)passive, inchoative and impersonal. This work identifies the relationships among the different uses of the marker and puts forward explanations for them within a cognitive, functional framework. Following studies such as those by Faltz (1985), Haiman (1983), Haspelmath (2005), Kemmer (1993ab), Lakoff (1977), Manoliu-Manea (1994, 2000), Maldonado (1992, 1999), Manney (2000), and Yoshimura and Taylor (2004), the current paper gives a synchronic account of the Romanian Middle Domain, its organization and the relationships between the various middle constructions found inside it. Findings suggest that the semantic property of low elaboration of events (introduced by Kemmer, 1993ab) constitutes the common denominator among the different uses explored. This work provides an insight into Romanian itself, as well as a contribution to cognitive theories of human language and responds to the call for more data and further investigations of middles cross-linguistically (see Smith, 2004).


2016 ◽  
Vol 90 (1-2) ◽  
pp. 1-27
Author(s):  
Giulia Bonacci

Twenty-eight years ago, F.J. van Dijk published in the New West Indian Guide what remained for a long time the only scholarly paper on the Twelve Tribes of Israel. Undoubtedly the largest Rastafari organization both in terms of membership and international expansion, the Twelve Tribes of Israel remains little known in public and academic circles. This article fills two major but closely related gaps in Van Dijk’s seminal article. The first is information on the formation and history of the Twelve Tribes, and the second is how the organization mobilized the return of members to Africa, a cornerstone of Rastafari belief. This article argues that the issue of return to the continent determined the very genesis of the organization and subsequently the development of its eighteen international branches. In its turn, this focus on return to Africa offers another perspective on the internal dynamics of the Rastafari movement, namely the structuring role of Rastafari organizations, a role which challenges the common image of Rastafari as an “acephalous” movement. Exploring the tangible relationship of Rastafari with Ethiopia, through the return to Ethiopia of members of the Twelve Tribes of Israel, offers new insight into the history of the Rastafari movement.


2020 ◽  
Vol 228 (1) ◽  
pp. 1-2
Author(s):  
Michael Bošnjak ◽  
Nadine Wedderhoff

Abstract. This editorial gives a brief introduction to the six articles included in the fourth “Hotspots in Psychology” of the Zeitschrift für Psychologie. The format is devoted to systematic reviews and meta-analyses in research-active fields that have generated a considerable number of primary studies. The common denominator is the research synthesis nature of the included articles, and not a specific psychological topic or theme that all articles have to address. Moreover, methodological advances in research synthesis methods relevant for any subfield of psychology are being addressed. Comprehensive supplemental material to the articles can be found in PsychArchives ( https://www.psycharchives.org ).


1970 ◽  
Vol 7 (2) ◽  
pp. 113-116
Author(s):  
Amimah Fatima Asif

Quality healthcare delivery is the bedrock to exponentially accelerate the development of a country. Unfortunately, in Pakistan healthcare has been neglected since a long time, with the common man bearing the brunt of this acute situation. There are critical challenges in health care, with paucity of trained human resource and deficit of regulated infrastructure and service delivery being the predominant dilemmas. Primary and secondary healthcare are in an unseemly state, to say the least. Maternal and child health care, accident, and emergency departments and mental health are among the most undermined and forsaken areas of healthcare, primarily in the far flung Gilgit Baltistan region of Pakistan. The only way forward is if the political regime, administration and the medical personnel work in concurrence to revise the health infrastructure of the country.


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