scholarly journals Using a Deep Learning Model to Explore the Impact of Clinical Data on COVID-19 Diagnosis Using Chest X-ray

Sensors ◽  
2022 ◽  
Vol 22 (2) ◽  
pp. 669
Author(s):  
Irfan Ullah Khan ◽  
Nida Aslam ◽  
Talha Anwar ◽  
Hind S. Alsaif ◽  
Sara Mhd. Bachar Chrouf ◽  
...  
Keyword(s):  
Deep Learning ◽  
Clinical Data ◽  
Disease Diagnosis ◽  
University Hospital ◽  
X Ray ◽  
Clinical Patient ◽  
Proposed Model ◽  
Chest X Ray ◽  
The Impact ◽  
Deep Learning Model

The coronavirus pandemic (COVID-19) is disrupting the entire world; its rapid global spread threatens to affect millions of people. Accurate and timely diagnosis of COVID-19 is essential to control the spread and alleviate risk. Due to the promising results achieved by integrating machine learning (ML), particularly deep learning (DL), in automating the multiple disease diagnosis process. In the current study, a model based on deep learning was proposed for the automated diagnosis of COVID-19 using chest X-ray images (CXR) and clinical data of the patient. The aim of this study is to investigate the effects of integrating clinical patient data with the CXR for automated COVID-19 diagnosis. The proposed model used data collected from King Fahad University Hospital, Dammam, KSA, which consists of 270 patient records. The experiments were carried out first with clinical data, second with the CXR, and finally with clinical data and CXR. The fusion technique was used to combine the clinical features and features extracted from images. The study found that integrating clinical data with the CXR improves diagnostic accuracy. Using the clinical data and the CXR, the model achieved an accuracy of 0.970, a recall of 0.986, a precision of 0.978, and an F-score of 0.982. Further validation was performed by comparing the performance of the proposed system with the diagnosis of an expert. Additionally, the results have shown that the proposed system can be used as a tool that can help the doctors in COVID-19 diagnosis.

scholarly journals A deep learning framework to detect Covid-19 disease via chest X-ray and CT scan images

2021 ◽  
Vol 11 (1) ◽  
pp. 844
Author(s):  
Mohammed Y. Kamil
Keyword(s):  
Deep Learning ◽  
High Performance ◽  
Early Stage ◽  
Diagnostic Technique ◽  
Disease Diagnosis ◽  
X Ray ◽  
Learning Framework ◽  
Chest X Ray ◽  
Low Sensitivity ◽  
Deep Learning Model

COVID-19 disease has rapidly spread all over the world at the beginning of this year. The hospitals' reports have told that low sensitivity of RT-PCR tests in the infection early stage. At which point, a rapid and accurate diagnostic technique, is needed to detect the Covid-19. CT has been demonstrated to be a successful tool in the diagnosis of disease. A deep learning framework can be developed to aid in evaluating CT exams to provide diagnosis, thus saving time for disease control. In this work, a deep learning model was modified to Covid-19 detection via features extraction from chest X-ray and CT images. Initially, many transfer-learning models have applied and comparison it, then a VGG-19 model was tuned to get the best results that can be adopted in the disease diagnosis. Diagnostic performance was assessed for all models used via the dataset that included 1000 images. The VGG-19 model achieved the highest accuracy of 99%, sensitivity of 97.4%, and specificity of 99.4%. The deep learning and image processing demonstrated high performance in early Covid-19 detection. It shows to be an auxiliary detection way for clinical doctors and thus contribute to the control of the pandemic.

scholarly journals Metaheuristic-based Deep COVID-19 Screening Model from Chest X-Ray Images

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Manjit Kaur ◽  
Vijay Kumar ◽  
Vaishali Yadav ◽  
Dilbag Singh ◽  
Naresh Kumar ◽  
...  
Keyword(s):  
Deep Learning ◽  
Learning Models ◽  
Huge Number ◽  
X Ray ◽  
Screening Model ◽  
Proposed Model ◽  
Strength Pareto Evolutionary Algorithm ◽  
Chest X Ray ◽  
Deep Learning Model

COVID-19 has affected the whole world drastically. A huge number of people have lost their lives due to this pandemic. Early detection of COVID-19 infection is helpful for treatment and quarantine. Therefore, many researchers have designed a deep learning model for the early diagnosis of COVID-19-infected patients. However, deep learning models suffer from overfitting and hyperparameter-tuning issues. To overcome these issues, in this paper, a metaheuristic-based deep COVID-19 screening model is proposed for X-ray images. The modified AlexNet architecture is used for feature extraction and classification of the input images. Strength Pareto evolutionary algorithm-II (SPEA-II) is used to tune the hyperparameters of modified AlexNet. The proposed model is tested on a four-class (i.e., COVID-19, tuberculosis, pneumonia, or healthy) dataset. Finally, the comparisons are drawn among the existing and the proposed models.

scholarly journals Cardiac or Infectious? Transfer Learning with Chest X-Rays for ER Patient Classification

2020 ◽  
Author(s):  
Jonathan Stubblefield ◽  
Mitchell Hervert ◽  
Jason Causey ◽  
Jake Qualls ◽  
Wei Dong ◽  
...  
Keyword(s):  
Deep Learning ◽  
Clinical Data ◽  
Image Data ◽  
Learning Model ◽  
Patient Classification ◽  
X Rays ◽  
Data Set ◽  
X Ray ◽  
Chest X Ray ◽  
Deep Learning Model

AbstractOne of the challenges with urgent evaluation of patients with acute respiratory distress syndrome (ARDS) in the emergency room (ER) is distinguishing between cardiac vs infectious etiologies for their pulmonary findings. We evaluated ER patient classification for cardiac and infection causes with clinical data and chest X-ray image data. We show that a deep-learning model trained with an external image data set can be used to extract image features and improve the classification accuracy of a data set that does not contain enough image data to train a deep-learning model. We also conducted clinical feature importance analysis and identified the most important clinical features for ER patient classification. This model can be upgraded to include a SARS-CoV-2 specific classification with COVID-19 patients data. The current model is publicly available with an interface at the web link: http://nbttranslationalresearch.org/.Data statementThe clinical data and chest x-ray image data for this study were collected and prepared by the residents and researchers of the Joint Translational Research Lab of Arkansas State University (A-State) and St. Bernards Medical Center (SBMC) Internal Medicine Residency Program. As data collection is on-going for the project stage-II of clinical testing, raw data is not currently available for data sharing to the public.EthicsThis study was approved by the St. Bernards Medical Center’s Institutional Review Board (IRB).

scholarly journals Transfer Learning Based Multiclass Classification For Covid-19 Detection Using Chest X-Rays

2021 ◽  
Author(s):  
Japman Singh Monga ◽  
Yuvraj Singh Champawat ◽  
Seema Kharb
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
X Rays ◽  
Performance Parameters ◽  
Chain Reaction ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Deep Learning Model

Abstract In the year 2020 world came to a halt due to spread of Covid-19 or SARS-CoV2 which was first identified in Wuhan, China. Since then, it has caused plethora of problems around the globe such as loss of millions of lives, economic instability etc. Less effectiveness of detection through Reverse Transcription Polymerase Chain Reaction and also prolonged time needed for detection through the same calls for a substitute for Covid-19 detection. Hence, in this study, we aim to develop a transfer learning based multi-class classifier using Chest X-Ray images which will classify the X-Ray images in 3 classes (Covid-19, Pneumonia, Normal). Further, the proposed model has been trained with deep learning classifiers namely: DenseNet201, Xception, ResNet50V2, VGG16, VGG-19, InceptionResNetV2 .These are evaluated on the basis of accuracy, precision and recall as performance parameters. It has been observed that DenseNet201 is the best deep learning model with 82.2% accuracy.

scholarly journals Transfer Learning Based Multiclass Classification For Covid-19 Detection Using Chest X-Rays

2021 ◽  
Author(s):  
Japman Singh Monga ◽  
Yuvraj Singh Champawat ◽  
Seema Kharb
Keyword(s):  
Deep Learning ◽  
Transfer Learning ◽  
X Rays ◽  
Performance Parameters ◽  
Chain Reaction ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Deep Learning Model

Abstract In the year 2020 world came to a halt due to spread of Covid-19 or SARS-CoV2 which was first identified in Wuhan, China. Since then, it has caused plethora of problems around the globe such as loss of millions of lives, economic instability etc. Less effectiveness of detection through Reverse Transcription Polymerase Chain Reaction and also prolonged time needed for detection through the same calls for a substitute for Covid-19 detection. Hence, in this study, we aim to develop a transfer learning based multi-class classifier using Chest X-Ray images which will classify the X-Ray images in 3 classes (Covid-19, Pneumonia, Normal). Further, the proposed model has been trained with deep learning classifiers namely: DenseNet201, Xception, ResNet50V2, VGG16, VGG-19, InceptionResNetV2 .These are evaluated on the basis of accuracy, precision and recall as performance parameters. It has been observed that DenseNet201 is the best deep learning model with 82.2% accuracy.

scholarly journals A Deep Learning Model with Self-Supervised Learning and Attention Mechanism for COVID-19 Diagnosis Using Chest X-ray Images

Electronics ◽  
2021 ◽  
Vol 10 (16) ◽  
pp. 1996
Author(s):  
Junghoon Park ◽  
Il-Youp Kwak ◽  
Changwon Lim
Keyword(s):  
Deep Learning ◽  
Supervised Learning ◽  
Learning Model ◽  
Fine Tuning ◽  
Classification Model ◽  
World Health ◽  
X Ray ◽  
Proposed Model ◽  
Chest X Ray ◽  
Deep Learning Model

The SARS-CoV-2 virus has spread worldwide, and the World Health Organization has declared COVID-19 pandemic, proclaiming that the entire world must overcome it together. The chest X-ray and computed tomography datasets of individuals with COVID-19 remain limited, which can cause lower performance of deep learning model. In this study, we developed a model for the diagnosis of COVID-19 by solving the classification problem using a self-supervised learning technique with a convolution attention module. Self-supervised learning using a U-shaped convolutional neural network model combined with a convolution block attention module (CBAM) using over 100,000 chest X-Ray images with structure similarity (SSIM) index captures image representations extremely well. The system we proposed consists of fine-tuning the weights of the encoder after a self-supervised learning pretext task, interpreting the chest X-ray representation in the encoder using convolutional layers, and diagnosing the chest X-ray image as the classification model. Additionally, considering the CBAM further improves the averaged accuracy of 98.6%, thereby outperforming the baseline model (97.8%) by 0.8%. The proposed model classifies the three classes of normal, pneumonia, and COVID-19 extremely accurately, along with other metrics such as specificity and sensitivity that are similar to accuracy. The average area under the curve (AUC) is 0.994 in the COVID-19 class, indicating that our proposed model exhibits outstanding classification performance.

scholarly journals Accessory pathway analysis using a multimodal deep learning model

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Makoto Nishimori ◽  
Kunihiko Kiuchi ◽  
Kunihiro Nishimura ◽  
Kengo Kusano ◽  
Akihiro Yoshida ◽  
...  
Keyword(s):  
Deep Learning ◽  
Electrophysiological Study ◽  
Accessory Pathway ◽  
Learning Model ◽  
X Rays ◽  
X Ray ◽  
Wpw Syndrome ◽  
Chest X Ray ◽  
Deep Learning Model ◽  
Ecg Data

AbstractCardiac accessory pathways (APs) in Wolff–Parkinson–White (WPW) syndrome are conventionally diagnosed with decision tree algorithms; however, there are problems with clinical usage. We assessed the efficacy of the artificial intelligence model using electrocardiography (ECG) and chest X-rays to identify the location of APs. We retrospectively used ECG and chest X-rays to analyse 206 patients with WPW syndrome. Each AP location was defined by an electrophysiological study and divided into four classifications. We developed a deep learning model to classify AP locations and compared the accuracy with that of conventional algorithms. Moreover, 1519 chest X-ray samples from other datasets were used for prior learning, and the combined chest X-ray image and ECG data were put into the previous model to evaluate whether the accuracy improved. The convolutional neural network (CNN) model using ECG data was significantly more accurate than the conventional tree algorithm. In the multimodal model, which implemented input from the combined ECG and chest X-ray data, the accuracy was significantly improved. Deep learning with a combination of ECG and chest X-ray data could effectively identify the AP location, which may be a novel deep learning model for a multimodal model.

scholarly journals Machine learning applied on chest x-ray can aid in the diagnosis of COVID-19: a first experience from Lombardy, Italy

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Isabella Castiglioni ◽  
Davide Ippolito ◽  
Matteo Interlenghi ◽  
Caterina Beatrice Monti ◽  
Christian Salvatore ◽  
...  
Keyword(s):  
Deep Learning ◽  
Area Under The Curve ◽  
Clinical Information ◽  
Training Dataset ◽  
Independent Dataset ◽  
X Ray ◽  
Learning Classifier ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Deep Learning Model

Abstract Background We aimed to train and test a deep learning classifier to support the diagnosis of coronavirus disease 2019 (COVID-19) using chest x-ray (CXR) on a cohort of subjects from two hospitals in Lombardy, Italy. Methods We used for training and validation an ensemble of ten convolutional neural networks (CNNs) with mainly bedside CXRs of 250 COVID-19 and 250 non-COVID-19 subjects from two hospitals (Centres 1 and 2). We then tested such system on bedside CXRs of an independent group of 110 patients (74 COVID-19, 36 non-COVID-19) from one of the two hospitals. A retrospective reading was performed by two radiologists in the absence of any clinical information, with the aim to differentiate COVID-19 from non-COVID-19 patients. Real-time polymerase chain reaction served as the reference standard. Results At 10-fold cross-validation, our deep learning model classified COVID-19 and non-COVID-19 patients with 0.78 sensitivity (95% confidence interval [CI] 0.74–0.81), 0.82 specificity (95% CI 0.78–0.85), and 0.89 area under the curve (AUC) (95% CI 0.86–0.91). For the independent dataset, deep learning showed 0.80 sensitivity (95% CI 0.72–0.86) (59/74), 0.81 specificity (29/36) (95% CI 0.73–0.87), and 0.81 AUC (95% CI 0.73–0.87). Radiologists’ reading obtained 0.63 sensitivity (95% CI 0.52–0.74) and 0.78 specificity (95% CI 0.61–0.90) in Centre 1 and 0.64 sensitivity (95% CI 0.52–0.74) and 0.86 specificity (95% CI 0.71–0.95) in Centre 2. Conclusions This preliminary experience based on ten CNNs trained on a limited training dataset shows an interesting potential of deep learning for COVID-19 diagnosis. Such tool is in training with new CXRs to further increase its performance.

scholarly journals Evolving Deep Learning Convolutional Neural Networks for Early COVID-19 Detection in Chest X-ray Images

Mathematics ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1002
Author(s):  
Mohammad Khishe ◽  
Fabio Caraffini ◽  
Stefan Kuhn
Keyword(s):  
Deep Learning ◽  
Early Detection ◽  
Iterative Process ◽  
High Accuracy ◽  
X Ray ◽  
Starting Point ◽  
Reliable Model ◽  
Minimum Number ◽  
Chest X Ray ◽  
Deep Learning Model

This article proposes a framework that automatically designs classifiers for the early detection of COVID-19 from chest X-ray images. To do this, our approach repeatedly makes use of a heuristic for optimisation to efficiently find the best combination of the hyperparameters of a convolutional deep learning model. The framework starts with optimising a basic convolutional neural network which represents the starting point for the evolution process. Subsequently, at most two additional convolutional layers are added, at a time, to the previous convolutional structure as a result of a further optimisation phase. Each performed phase maximises the the accuracy of the system, thus requiring training and assessment of the new model, which gets gradually deeper, with relevant COVID-19 chest X-ray images. This iterative process ends when no improvement, in terms of accuracy, is recorded. Hence, the proposed method evolves the most performing network with the minimum number of convolutional layers. In this light, we simultaneously achieve high accuracy while minimising the presence of redundant layers to guarantee a fast but reliable model. Our results show that the proposed implementation of such a framework achieves accuracy up to 99.11%, thus being particularly suitable for the early detection of COVID-19.

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