scholarly journals EXPERT STUDY OF ISONIAZIDE IN MEAT PRODUCTS

2021 ◽  
pp. 785-799
Author(s):  
S. Shkurdoda ◽  
D. Shynkarenko ◽  
V. Pasichnyk ◽  
K. Korol ◽  
O. Posilskyi
Keyword(s):  
Gas Chromatography ◽  
Meat Products ◽  
Domestic Animals ◽  
Selective Detection ◽  
Gas Chromatograph ◽  
Liquid Chromatograph ◽  
Mass Selective Detector ◽  
Selective Detector ◽  
Minced Meat ◽  
Layer Chromatography

The article deals with the recommendations for the detection of isoniazid in meat products, using the example of minced meat using physicochemical methods. This study does not lose its relevance over the years, due to the use of drugs for tuberculosis for poisoning homeless and domestic animals, in particular dogs, in different regions of Ukraine, the main active ingredient of which is isoniazid. The article describes a method for the extraction of isoniazid in food products of meat origin (minced meat, sausage), which presumably could or may be used to poison domestic animals, in particular dogs. Isoniazid was identified by the methods of qualitative color reactions, thin-layer chromatography, and gas chromatography with a mass-selective detector. The process of qualitative identification of isoniazid in foodstuffs that could or may be used to poison domestic animals, in particular dogs, includes: -the method of extraction and separation of interfering impurities, primarily fats, preliminary research by the method of qualitative analytical reactions; -studies by thin layer chromatography; -research by instrumental methods, in particular, gas chromatography with mass-selective detection. The method for extracting isoniazid from meat products described in the article is effective and allows you to get rid of interfering substances, especially fats. In addition, the method of gas chromatography with mass-selective detection has sufficient sensitivity and selectivity. It allows with a minimum number of interfering peaks of low intensity, determine the composition of isoniazid accurately. The specified list of instrumental base, methods and research techniques is not exhaustive. The examiner should be guided by the availability of relevant literature and the availability of appropriate analytical equipment (gas chromatograph, gas chromatograph with mass-selective detector, liquid chromatograph, liquid chromatograph with mass-selective detector, etc.). In accordance with this, it is necessary to use certain methods for studying substances. These methods are subject to mandatory verification before being used in the laboratory. The obtained research results allow us to recommend this technique for implementation in expert practice.

scholarly journals Multiresidue Method for the Determination of Pesticides in Korean Domestic Crops by Gas Chromatography/Mass Selective Detection

2003 ◽  
Vol 86 (4) ◽  
pp. 823-831 ◽  
Author(s):  
Ock Kyoung Chun ◽  
Hee Gon Kang ◽  
Myung Hee Kim
Keyword(s):  
Gas Chromatography ◽  
Retention Time ◽  
Selective Detection ◽  
Selected Ion Monitoring ◽  
Limits Of Detection ◽  
Multiresidue Method ◽  
Mass Selective Detector ◽  
Chrysanthemum Coronarium ◽  
Selective Detector

Abstract The multiresidue method used in this study allows the determination of 101 pesticides, including organophosphorus, organochlorine, and nitrogen-containing pesticides, in crops by gas chromatography with mass selective detector. Analysis was performed in the selected–ion monitoring mode, and the identities of the positive analytes were confirmed by retention time and the ratios of selected ions. The selected ion mode demonstrated an acceptable selectivity for most of the pesticides determined in 3 kinds of samples (Chrysanthemum coronarium; Perilla japonica, leaf; and Lactuca savita, which are very popular vegetables eaten raw in Korea), and very minor interferences were observed in the elution area of the pesticide analytes. Samples were spiked with pesticides at 0.1–1.0 mg/kg. The recoveries of 90% of the pesticides were between 70 and 110%; however, the recoveries of acephate and folpet were very poor, i.e., <50%. The limits of detection (LODs) for most pesticides were between 0.02 and 0.3 mg/kg, and the LODs for about half of the pesticeds studied were <0.05 mg/kg.

Gas Chromatographic Determination Of Residue Levels Of The Herbicides Trifluralin, Benefin, Ethalfluralin, And Isopropalin In Soil With Confirmation By Mass Selective Detection

1988 ◽  
Vol 71 (6) ◽  
pp. 1082-1085 ◽  
Author(s):  
Sheldon D West ◽  
Jack H Weston ◽  
Edgar W Day
Keyword(s):  
Gas Chromatography ◽  
Electron Capture ◽  
Limit Of Detection ◽  
Detection System ◽  
Gas Chromatography Mass Spectrometry ◽  
Electron Capture Detection ◽  
Selective Detection ◽  
Mass Selective Detector ◽  
Selective Detector

Abstract A method is presented for the simultaneous or individual determination of the dinitroaniline herbicides trifluralin, benefin, ethalfluralin, and isopropalin in soil. The herbicides are extracted with acetonitrile- water (99 + 1), and the extracts are purified with small, disposable Florisil cartridges prior to analysis by gas chromatography using an electron capture detector or a mass selective detector. When electron capture detection is used as the primary detection system, confirmation with selective detection can be obtained using gas chromatography-mass spectrometry with a mass selective detector and a capillary column operated in the split mode. The limit of detection is 0.01 ppm, and recoveries averaged 95-112% for the 4 herbicides in several different soil types fortified at levels of 0.01- 0.33 ppm

scholarly journals Determina tion of diacetyl and 2,3-pentanedione in beer by gc/ms using solid-phase extraction columns

2002 ◽  
pp. 45-54 ◽  
Author(s):  
Jelena Pejin ◽  
Olgica Grujic ◽  
Nikola Marjanovic ◽  
Djura Vujic ◽  
Suncica Kocic-Tanackov
Keyword(s):  
Gas Chromatography ◽  
Solid Phase Extraction ◽  
Simultaneous Determination ◽  
Solid Phase ◽  
Phase Extraction ◽  
Mass Selective Detector ◽  
Selective Detector

A new GC/MS method for the determination of diacetyl and 2,3-pentanedione was investigated. Diacetyl and 2,3-pentanedione were derivatized with 1,2-diaminobenzene to form 2,3-dimetylquinoxaline and 2-ethyl-3-methylquinoxaline. respectively. The amounts of formed 2.3-dimetylqu:inoxaline and 2-ethyl-3,.methylquinoxaline were proportional to the concentrations of diacetyl and 2,3-penianedione present in the sample. 2,3-Dimetylquinoxaline and 2-ethyl-3-methylquinoxaline were extracted by solid-phase extraction (SPE) columns and determined by gas chromatography using a mass selective detector. This method was applied for the determination of diacetyl and 2,3-pentanedione concentrations in beer. Extraction by SPE columns proved to be very simple and reliable. The method can be used for simultaneous determination of diacetyl and 2,3-pentanedione concentrations in beer in a great number of beer samples.

scholarly journals Optimal Extraction of Ocimum basilicum Essential Oil by Association of Ultrasound and Hydrodistillation and Its Potential as a Biopesticide Against a Major Stored Grains Pest

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2781 ◽  
Author(s):  
Eridiane da Silva Moura ◽  
Lêda Rita D’Antonino Faroni ◽  
Fernanda Fernandes Heleno ◽  
Alessandra Aparecida Zinato Rodrigues ◽  
Lucas Henrique Figueiredo Prates ◽  
...  
Keyword(s):  
Biological Activity ◽  
Essential Oil ◽  
Insect Pests ◽  
Extraction Process ◽  
Ocimum Basilicum ◽  
Gas Chromatograph ◽  
Drying Temperature ◽  
Mass Selective Detector ◽  
Potential Control ◽  
Selective Detector

The essential oil of basil (Ocimum basilicum) has significant biological activity against insect pests and can be extracted through various techniques. This work aimed to optimize and validate the extraction process of the essential oil of O. basilicum submitted to different drying temperatures of the leaves and extracted by the combination of a Clevenger method and ultrasound. The biological activity of the extracted oil under different conditions was evaluated for potential control of Sitophilus zeamais. The extraction method was optimized according to the sonication time by ultrasound (0, 8, 19, 31 and 38 min) and hydrodistillation (20, 30, 45, 60 and 70 min) and drying temperature (20, 30, 45, 60 and 70 °C). The bioactivity of the essential oil was assessed against adults of S. zeamais and the effects of each variable and its interactions on the mortality of the insects were evaluated. The best yield of essential oil was obtained with the longest sonication and hydrodistillation times and the lowest drying temperature of leaves. Higher toxicity of the essential oil against S. zeamais was obtained by the use of ultrasound for its extraction. The identification and the relative percentage of the compounds of the essential oil were performed with a gas chromatograph coupled to a mass selective detector. The performance of the method was assessed by studying selectivity, linearity, limits of detection (LOD) and quantification (LOQ), precision and accuracy. The LOD and LOQ values for linalool were 2.19 and 6.62 µg mL−1 and for estragole 2.001 and 6.063 µg mL−1, respectively. The coefficients of determination (R2) were >0.99. The average recoveries ranged between 71 and 106%, with coefficient of variation ≤6.4%.

Analytical toxicology: Applications of element-selective electrolytic conductivity detection for gas chromatography.

1976 ◽  
Vol 22 (6) ◽  
pp. 739-748 ◽  
Author(s):  
B E Pape
Keyword(s):  
Gas Chromatography ◽  
Selective Detection ◽  
Qualitative And Quantitative Analysis ◽  
Furnace Temperature ◽  
Analytical Toxicology ◽  
Qualitative And Quantitative ◽  
Relative Response ◽  
Selective Detector ◽  
Sulfur Containing ◽  
Sulfur Containing Compounds

Abstract We applied a commercially available microelectrolytic conductivity detector to toxicological problems of qualitative and quantitative analysis by gas chromatography. The detector can be used for the sensitive and selective detection of halogen-, nitrogen-, and sulfur-containing compounds. Relative response in different element-selective detector variables such as reaction gas, reaction catalyst, and furnace temperature can be used to further improve qualitative identification by gas chromatography.

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