GARLAND CHRYSANTHEMUM IS A PROMISING NEW MEDICINAL PLANT

A brief overview of the relevance of using garland chrysanthemum (Glebionis coronaria (L.) Cass. ex Spach syn. Chrysanthemum coronarium (L.)) as a raw material in the preparation of medicaments is introduced in this article. High content of micro- and macroelements (K, Na, Ca, P, Zn, Fe, Cu, Mn, J) was found in garland chrysanthemum, as well as other biologically active compounds, of which anthraquinones (emodin, chrysophanol), flavonoids (quercetin, rutin), carotenoids and ascorbic acid (up to 56.0 mg%) can be considered the main ones, likewise vitamins B, PP and free amino acids (lysine, methionine, cysteine, histidine, arginine, threonine, serine, proline, glycine, valine, isoleucine, leucine, tyrosine, phenylalanine; nine of which are essential). These elements have a positive therapeutic effect on the cardiovascular system, the human gastrointestinal tract. The garland chrysanthemum is a very plastic and undemanding vegetable crop with medicinal properties. It is capable of growing on technogenic soils contaminated with cobalt, zinc and nickel, accumulating these elements to a lesser extent than traditional vegetable plants, which is very important in modern conditions. It is shown that in the conditions of the Moscow region it can be well grown by sowing seeds directly on field, continues to maintain the rhythms of growth and development, passes through all phenological phases and gives a stable high yield of green mass — up to 5.3 kg/m2, inflorescences — up to 1.4 kg/m2, seeds — up to 130.0 g/m2. Low laboratory and field germination of seeds up to 50 % has been established.

Flora y vegetación de las dunas de la Playa Grande de Cartagena, una playa urbana en Chile central

The flora of the Playa Grande of Cartagena in the Valparaiso Region, commune of El Tabo (33°30´S, 71°36´W), is made up of 98 species of vascular plants, 61 % of which are exotics, most feral. The vegetation is made up of five units: a Carpobrotus chilensis and Chrysanthemum coronarium grassland dominated by ruderal species, mostly feral alien species, which marks the boundary between the populated area and the dune field with the sandy beach; a Ambrosia chamissonis and Poa cumingii scrub that is typical of the primary and secondary dunes and occupies the largest vegetated area in the study area; a Nolana crassulifolia scrub, a coastal rocky rocks; and two units typical of coastal wetlands: a marsh grassland with Schoenoplectus pungens and Cotula coronopifolia, and a Typha dominguensis grassland in a water body.

Preventive Effects of Chrysanthemum coronarium L. Extract on Bone Metabolism In Vitro and In Vivo

Osteoporosis is characterized by decreased bone mass and bone microarchitectural failure, leading to an enhanced risk of bone fractures. Chrysanthemum coronarium L. (CC) is a natural plant with powerful antioxidant activity. This study investigated the antiosteoporotic effects of CC extracts in in vitro cell cultures and in vivo bone loss animal models. CC stimulated osteoblast differentiation and mineralized bone formation by osteoblasts by increasing the expression of bone formation markers (alkaline phosphatase, osteoprotegerin, and osteoprotegerin/receptor activator nuclear factor-κB ligand ratio) in the murine preosteoblastic cell line MC3T3-E1. Additionally, CC was found to inhibit osteoclast differentiation by downregulating bone resorption markers (tartrate-resistant acid phosphatase, cathepsin K, dendritic cell-specific transmembrane protein, and calcitonin receptor) in the murine macrophage-like cell line RAW264.7. CC prevented ovariectomy-induced bone loss, preserved trabecular microarchitecture, and improved serum bone turnover markers in an osteoporotic mouse model. These findings suggest that CC extract may be considered as a natural therapeutic or preventive agent for osteoporotic bone loss.

Valorisation d’une adventice poussant en Algérie : Chrysanthemum coronarium L

De nombreuses plantes aromatiques, considérées parfois comme adventices, possèdent des propriétés biologiques très intéressantes dont l’application s’étend à divers domaines telles que la médecine, la pharmacie, la cosmétologie et l’agriculture. Ce travail, réalisé sur l’huile essentielle des capitules de Chrysanthemum coronarium L., a pour objectifs de localiser les sites sécréteurs, de recenser les différents composés biochimiques et d’évaluer certains effets thérapeutiques. L’étude microscopique a montré la présence des glandes sécrétrices sessiles et des papilles responsables de la sécrétion de l’huile essentielle au niveau des capitules du chrysanthème à couronne. L’analyse par CG/MS de l’huile essentielle des capitules du chrysanthème à couronne, dont le rendement est de 0,15%, a permis l’identification de 57 constituants (89,51%) dont certains sont majoritaires, tels que l’ester d’acide acétoacétique, de 3(10)carèn-4-ol (14,01%) et l’acétate de verbanyle (8,20%). Malgré sa faible activité antimicrobienne, l’huile essentielle des capitules de Chrysanthemum coronarium L. testée sur 11 microorganismes par la méthode de diffusion sur Gélose se distingue par une activité remarquable sur Bacillus subtilis avec une zone d’inhibition de 20,33 mm ± 0,58. L’huile essentielle possède un effet anti-inflammatoire comparable à celui du diclofénac à une concentration de 50 mg/kg avec un pourcentage de réduction d’œdème de 46,95%.

Prospects for the use of Chrysanthemum coronarium (L.) in medicinal crop production

А brief overview of the relevance of using garland chrysanthemum (Glebionis coronaria (L.) Cass. ex Spach syn. Chrysanthemum coronarium (L.)) as a raw material in the preparation of medicaments is introduced in this article. High contents of micro- and macroelements were found in garland chrysanthemum, as well as other biologically active compounds, of which anthraquinones, flavonoids, carotenoids and ascorbic acid can be considered the main ones, likewise vitamins B, PP and free amino acids.