SUGGESTION A SIMPLE SCREENING SCORE FOR PRE-DIABETES AND UNDIAGNOSED TYPE 2 DIABETES FOR THE VIETNAM POPULATION
Objectives: We suggested and validated a self-assessment score for diabetes risk in Vietnamese adults and compared it with other established screening models. Methods: A cross sectional study of 131 subjects (over 45 years old without previous diabetes) were performed the test FPG, HbA1c and oral glucose tolerance tests, and then applied the diabetes risk scores including FINDRISC, IDRS, FRAMINGHAM OFFSPRING, THAI SCORE, DESIR and AUSDRISC for predicting the type 2 diabetes mellitus and screening to prediabetes and undiagnosed diabetes. Logistic regression was used to determine the independent factors concerning diabetes. Results: The FINDRISC tool was more valuable for screening of the type 2 prediabetes and diabetes than the other scales. With plasma G2 levels ≥ 7.8 mmol: ROC-UAC of FINDRISC was 61.2%, the optimal cut points: 12 (Se = 32.7%; 1-Sp = 7.4%); with plasma G2 concentration ≥ 11.1 mmol: ROC-AUC of FINDRISC was 89.3%, the optimal cut point of 13 (Se = 90% 1-Sp = 22.3%). With HbA1c levels ≥ 5.7%: ROC-UAC was 76.3%, the optimal cut point of 9 (Se = 57.3%; 1-Sp = 7.1%), with HbA1c ≥ 6.5%: ROC-AUC was 86.7%, the optimal cut points: 13 (Se = 90.9%; 1-Sp = 21.7). Values for screening to prediabetes and diabetes in the VNDRISC 1 were 10 and 14 point and VNDRISC 2 were 12 and 16 point respectively, but the ROC-AUC of VNDRISC 2 was not significantly different than those VNDRISC 1. Conclusions: FINDRISC have most valuable screening prediabetes and undiagnosed type 2 diabetes in social (when change body mass index and waist circumference follow Vietnamese people) compaired with others score. VNDRISC 1 was the most valuable diabetes risk score for predicting the type 2 diabetes mellitus and screening to prediabetes and diabetes in subjects over 45 years old on the community.