scholarly journals A study on the relationship of cervical cancer with vaginal microbiota and trichomoniasis infection; a single center study

2021 ◽  
Vol 6 (2) ◽  
pp. e22-e22
Author(s):  
Pegah Hedayat ◽  
Maryam Derakhshan ◽  
Reda Bazzal

Introduction: Cervical cancer is the most prevalent cancer associated with infection, which is provoked by the human papillomavirus (HPV). Natural vaginal microbes, known as vaginal microbiota, play an important role in regulating vaginal pH and are therefore important in the risk of cervical cancer. Trichomoniasis vaginalis is a genital infection that reports 250 million new infections worldwide each year and can increase the risk of developing cervical cancer in the general population. Objectives: The aim of this study was to investigate the relationship between cervical cancer and vaginal microbiota or trichomoniasis infection by examining several risk factors. Patients and Methods: This prospective case study was conducted from 2014 to 2018 from an educational pathology group in Isfahan, 200 samples are included in this study. The groups consist of women over 18 years old. The study group included patients with cervical cancer lesions. For participants, a questionnaire containing information about age, gender, abortion, age at first delivery, smoking or passive smoking and the result of Pap smear test (HPV, vaginal microbiota or Trichomonas) was completed. Results: Results suggested that cancerous and precancerous lesion development is not associated with parity, age at first child’s birth. However, it is statistically associated with lower vaginal microbiota, increased Trichomonas infection, old age, increased abortion rate, smoking, and the presence of HPV infection on Pap smear. Conclusion: Protection from harmful factors that affect a healthy vaginal microbiome, such as Trichomonas infections, can reduce the risk of cervical cancer.

2020 ◽  
Vol 8 (2) ◽  
pp. 89-96
Author(s):  
Sri Aminingsih ◽  
Tunjung Sri Yulianti

Background. One cause of death of women in Indonesia is cancer, one of which is cervical cancer. According to the 2013 Riskesdas data the incidence of cancer in Central Java was 2.1% with 1.2% being cervical cancer. Cervical cancer swallows many female victims in Indonesia, although it should be prevented by making efforts to prevent and detect early, one of them by carrying out a pap smear examination. The Aim of the Study. Knowing the factors that affecting motivation conducting pap smear examination in woman of childbearing age. Subject and Method. The research was analytic correlation design. The population in this study were women of childbearing age in the village of Wiragunan in September 2019 to March 2020 totaling 60 respondents. The sampling technique used is saturation sampling technique. The results of the study were analyzed using the Chi-Square Correlation Test. Result. Respondents with high knowledge were 44 (73.33%), who had low knowledge of 16 respondents (26.67%). High family support there are 43 respondents (71.67%), low family support 17 respondents (28.33%). While respondents with high motivation 42 (70%) and low motivation 18 (30%). The results of the Chi Square analysis of the level of knowledge (p = 0.001), family support (p = 0.001) on the motivation to do the pap smear. Conclusion. There is a relationship of knowledge about cervical cancer with the motivation to conduct pap smears in women of childbearing age. And there is a relationship of family support with the motivation to do a pap smear test on women of childbearing age. Keywords : cervical cancer, family support, knowledge, motivation, pap smear test Korespondensi: Sri Aminingsih. STIKES PANTI KOSALA SURAKARTA. Jalan Raya Solo - Baki Km. 4 Gedangan, Grogol, Sukoharjo, Jawa Tengah. Email: [email protected].


Author(s):  
Kun Lee ◽  
Jingyi Si ◽  
Ricai Han ◽  
Wei Zhang ◽  
Bingbing Tan ◽  
...  

There are more supports for the view that human papillomavirus (HPV) infection might be an etiological factor in the development of cervical cancer when the association of persistent condylomata is considered. Biopsies from 318 cases with squamous cell carcinoma of uterine cervix, 48 with cervical and vulvar condylomata, 14 with cervical intraepithelial neoplasia (CIN), 34 with chronic cervicitis and 24 normal cervical epithelium were collected from 5 geographic regions of China with different cervical cancer mortalities. All specimens were prepared for Dot blot, Southern blot and in situ DNA-DNA hybridizations by using HPV-11, 16, 18 DNA labelled with 32P and 3H as probes to detect viral homologous sequences in samples. Among them, 32 cases with cervical cancer, 27 with condyloma and 10 normal cervical epitheliums were randomly chosen for comparative EM observation. The results showed that: 1), 192 out of 318 (60.4%) cases of cervical cancer were positive for HPV-16 DNA probe (Table I)


Author(s):  
Nguyen Thu Ha ◽  
Nguyen Thi Thanh Huyen

The retail market in Vietnam continues to grow with the entry of foreign retail brands and the strong rise of domestic businesses in expanding distribution networks and conquering consumer confidence. The appearance of more retail brands has created a fiercely competitive market. Based on the outcomes of previous research results on brand choice intention combined with a customer survey, the paper proposes an analytical framework and scales to examine the relationship of five elements including store image, price perception, risk perception, brand attitudes, brand awareness and retail brand choice intention with a case study of the Hanoi-based Circle K convenience store chain. These five elements are the precondition for retail businesses to develop their brands so as to attract customers.


2018 ◽  
Vol 2 (2) ◽  
pp. 115
Author(s):  
Taufik Abrain

Several studies have shown that the success of interregional cooperation may be influenced by coordination, commitment, participation, variance of cooperation, structure, format of cooperation, and political will. Nevertheless, these factors do not stand alone since actor relations as a determining aspect is capable of driving those factors effectively. This article aims to examine the aspect of actor relations as a contributing factor that determines successful cooperation among regions. This is a qualitative research with the policy of inter-regional cooperation of the Banjarbakula Program, South Kalimantan Province from February 2017 to February 2018, set as its object of study. The result of this study states that the success of inter-regional cooperation is influenced by the relationship of actors in development factors as suggested by previous experts. The actors involved in the inter-regional cooperation examined in this case had become triggers of coordination, commitment, and participation toward success and failure, as well as the effectiveness of regional cooperation policy. Structural obstacles, ego-centric character, minimum budget availability, and non-visionary planning could be overcome as long as actor relations were properly managed.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Sumarmi Sumarmi ◽  
Yu-Yun Hsu ◽  
Ya-Min Cheng ◽  
Shu-Hsin Lee

Abstract Purposes This study aimed to understand the influence of health beliefs, demographic factors, and health characteristics on the intention to undergo Pap smear testing among women in rural areas of Indonesia. Methods A descriptive cross-sectional study was conducted and 687 married women participated in the study. A convenience sampling was applied to recruit the participants from community health centres in a rural region in Indonesia. Self-reported data using the Health Beliefs Model Scale for Cervical Cancer and Pap Smear Test was collected to assess the health beliefs. Independent t-tests, simple logistic regressions, and a hierarchical logistic regression with 3 steps were run. Statistical significance for analysis was set at p < 0.05. Results The mean age of the participants was 42 years (SD = 8.4). Among the participants, 81% of the women had never undergone a Pap smear test, and 61% (n = 422) of the women reported a high intention of receiving a Pap smear test. Income and education Health beliefs regarding Pap smear testing were different between women who had low and high intentions to undergo Pap smear testing. Health beliefs, such as perceived benefits, severity, barriers to Pap smear testing, and health motivation for a Pap smear test were associated with the intention to undergo Pap smear testing among rural Indonesian women. Overall, the hierarchical multiple regression with 3 steps containing demographic, health characteristics, and health belief variables accounted for 31% variance of the intention to undergo Pap smear test among the Indonesian rural women. Conclusions Low screening rates of cervical cancer and high intentions to do the screening exist among rural Indonesian women. Health beliefs significantly affect the rural women’s intention of Pap smear testing in Indonesia.


2021 ◽  
Vol 11 (9) ◽  
pp. 4091
Author(s):  
Débora N. Diniz ◽  
Mariana T. Rezende ◽  
Andrea G. C. Bianchi ◽  
Claudia M. Carneiro ◽  
Daniela M. Ushizima ◽  
...  

Prevention of cervical cancer could be performed using Pap smear image analysis. This test screens pre-neoplastic changes in the cervical epithelial cells; accurate screening can reduce deaths caused by the disease. Pap smear test analysis is exhaustive and repetitive work performed visually by a cytopathologist. This article proposes a workload-reducing algorithm for cervical cancer detection based on analysis of cell nuclei features within Pap smear images. We investigate eight traditional machine learning methods to perform a hierarchical classification. We propose a hierarchical classification methodology for computer-aided screening of cell lesions, which can recommend fields of view from the microscopy image based on the nuclei detection of cervical cells. We evaluate the performance of several algorithms against the Herlev and CRIC databases, using a varying number of classes during image classification. Results indicate that the hierarchical classification performed best when using Random Forest as the key classifier, particularly when compared with decision trees, k-NN, and the Ridge methods.


2021 ◽  
Vol 1 (69) ◽  
pp. 6
Author(s):  
Gheorghe Cruciat ◽  
Iulia Popa ◽  
Suzana Mariam Chaikh-Sulaiman

2018 ◽  
Vol 23 ◽  
pp. 2515690X1880477
Author(s):  
Suzanne Reed ◽  
Kathi J. Kemper ◽  
Alan Schwartz ◽  
Maneesh Batra ◽  
Betty B. Staples ◽  
...  

Residency is a high-risk period for physician burnout. We aimed to determine the short-term stability of factors associated with burnout, application of these data to previous conceptual models, and the relationship of these factors over 3 months. Physician wellness questionnaire results were analyzed at 2 time points 3 months apart. Associations among variables within and across time points were analyzed. Logistic regression was used to predict burnout and compassionate care. A total of 74% of residents completed surveys. Over 3 months, burnout ( P = .005) and empathy ( P = .04) worsened. The most significant cross-sectional relationship was between stress and emotional exhaustion (time 1 r = 0.61, time 2 r = 0.68). Resilience was predictive of increased compassionate care and decreased burnout ( P < .05). Mindfulness was predictive of decreased burnout ( P < .05). Mitigating stress and fostering mindfulness and resilience longitudinally may be key areas of focus for improved wellness in pediatric residents. Larger studies are needed to better develop targeted wellness interventions.


2013 ◽  
Vol 3 (4) ◽  
pp. 128 ◽  
Author(s):  
Seema Qureshi

Managers play an important role in organizations. They are the persons who formulate and implement policies, plans etc in the organization. Managers are the first to be contacted for suggestions with regard to overall information about the organization. Taking into consideration the importance of managers in the organization and a critical review of literature which revealed that the study on work motivation, burnout and intention to leave has not been conducted so far on the top level managers of garment industry of Delhi and NCR, the researcher found a gap to be filled by  conducting investigation on this sample for the variables in question. So the sample of the present study consists of top level managers of garment industry of Delhi and NCR. Thus, a convenient sampling method was used for drawing the sample from 60 garment export houses of Delhi and 40 of NCR. This paper gives a deep insight of work motivation, burnout and intention to leave for the top level managers of the garment industry of Delhi/NCR. In this paper we have checked the relationship of all dimensions of work motivation with the dimensions of burnout and intention to leave and have observed that all dimensions of work motivation have some more or less relationship with each dimension of burnout but neither of the dimensions of work motivation or total work motivation have any relationship with intention to leave. So even if top level managers leave their current job they don’t leave because of lack of work motivation.


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