scholarly journals Human Immunodeficiency Virus Infectious Profile Change in Mali: A Narrative Review

2021 ◽  
pp. 1-8
Author(s):  
Nouhoum Bouare ◽  
Sebastien Bontems ◽  
Christiane Gerard
Keyword(s):  
Human Immunodeficiency Virus ◽  
Linear Regression ◽  
Linear Regression Model ◽  
Clinical Characteristics ◽  
Model Calculations ◽  
Immunodeficiency Virus ◽  
Bibliographic Search ◽  
Study Population ◽  
Hiv 1 ◽  
Profile Change

West Africa is reputed as an epicenter of HIV-2 infection. Studies undertaken in Mali suspected HIV-1 more prevalent. Our study aims to document HIV infectious profiles in Mali and analyze HIV-1 dominance. We documented HIV studies undertaken in Mali from1985 to 2010. We proceeded to a bibliographic search focused on theses from the Medicine Pharmacy Odontostomatology Faculty (FMPOS) of Bamako, survey reports, and abstracts or papers published in reviews with the reading committee. Documents were physically and virtually (via website) consulted and exploited. We gave preference to studies that discriminated against HIV serotypes. The data were analyzed according to study population/publication, representativeness, infectious profiles reporting, socio-demographic and clinical characteristics. HIV profiles variation in space and time was analyzed by using a linear regression model. Calculations were done using Excel software.

scholarly journals Rational Peptide Selection To Detect Human Immunodeficiency Virus Type 1-Specific T-Cell Responses under Resource-Limited Conditions

2007 ◽  
Vol 14 (6) ◽  
pp. 785-788 ◽  
Author(s):  
C. B. Willberg ◽  
S. K. Pillai ◽  
E. R. Sharp ◽  
M. G. Rosenberg ◽  
J. D. Agudelo ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Cytotoxic T Lymphocyte ◽  
Resource Limited ◽  
Immunodeficiency Virus ◽  
Study Population ◽  
Lymphocyte Responses ◽  
Hiv 1

ABSTRACT Understanding human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T-lymphocyte responses is important for the development of vaccines and therapies. We describe a novel method for the rational selection of peptides that target stable regions of the HIV-1 genome, rich in epitopes specifically recognized by the study population. This method will be of particular use under resource/sample-limited conditions.

DEVELOPMENT OF APPROACHES FOR DETECTION OF GENOME-INTEGRATED PROVIRAL DNA OF THE HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) IN ULTRA LOW CONCENTRATIONS USING THE CRISPR/CAS SYSTEM

2020 ◽  
Author(s):  
M.A. Tyumentseva ◽  
◽  
A.I. Tyumentsev ◽  
V.G. Akimkin ◽  
◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Health Monitoring ◽  
Biological Samples ◽  
Proviral Dna ◽  
Guide Rnas ◽  
Ribonucleoprotein Complexes ◽  
Low Concentrations ◽  
Immunodeficiency Virus ◽  
Hiv 1

For the effective functioning of supervisory and health monitoring services, it is necessary to introduce modern molecular technologies into their practice. Therefore, the task of developing new effective methods for detecting pathogen, for example HIV, based on CRISPR/CAS genome editing systems, remains urgent. In the present work, guide RNAs and specific oligonucleotides were developed for preliminary amplification of highly conserved regions of the HIV-1 genome. The developed guide RNAs make it possible to detect single copies of HIV-1 proviral DNA in vitro as part of CRISPR/CAS ribonucleoprotein complexes in biological samples after preliminary amplification.

Use of polimerase chain reaction for neonatal diagnosis of human immunodeficiency virus type 1 (HIV-1) perinatal infection

1994 ◽  
Vol 70 (6) ◽  
Author(s):  
Marisa Márcia Mussi-Pinhata ◽  
Maria Célia C. Ferez ◽  
Dimas T. Covas ◽  
Geraldo Duarte ◽  
Márcia L. Isaac ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Perinatal Infection ◽  
Chain Reaction ◽  
Neonatal Diagnosis ◽  
Immunodeficiency Virus ◽  
Hiv 1
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