scholarly journals Buccal ureteroplasty in a patient with an extended stricture of the proximal ureter of a solitary kidney

2021 ◽  
pp. 52-56
Author(s):  
A. A. Volkov ◽  
N. V. Budnik ◽  
I. D. Mustapaev
Keyword(s):  
Urinary Tract ◽  
Postoperative Complications ◽  
Clinical Case ◽  
Solitary Kidney ◽  
Nitinol Stent ◽  
Long Time ◽  
Proximal Ureter ◽  
Single Kidney

Buccal ureteroplasty is considered a rare operation in urology and the indications for its implementation are still not clearly defined. We have described a clinical case of successful replacement of a part of the proximal ureter with a buccal graft in a patient with a single kidney, which was drained for a long time with a nitinol stent, which was subsequently incrustated, which led to the installation of a permanent nephrostomy drainage. The patient had no postoperative complications, the patency of the urinary tract was fully restored.

scholarly journals Spontaneous one-kidney rats are more susceptible to develop hypertension by DOCA-NaCl and subsequent kidney injury compared with uninephrectomized rats

2016 ◽  
Vol 310 (10) ◽  
pp. F1054-F1064 ◽  
Author(s):  
Xuexiang Wang ◽  
Ashley C. Johnson ◽  
Jennifer M. Sasser ◽  
Jan M. Williams ◽  
Leah C. Solberg Woods ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Kidney Function ◽  
Time Course ◽  
Kidney Injury ◽  
Solitary Kidney ◽  
Course Evaluation ◽  
Significant Rise ◽  
Kidney Weight ◽  
Unilateral Renal Agenesis ◽  
Single Kidney

There is little clinical data of how hypertension may influence individuals with nephron deficiency in the context of being born with a single kidney. We recently developed a new rat model (the heterogeneous stock-derived model of unilateral renal agenesis rat) that is born with a single kidney and exhibits progressive kidney injury and decline in kidney function with age. We hypothesized that DOCA-salt would induce a greater increase in blood pressure and therefore accelerate the progression of kidney injury in rats born with a solitary kidney compared with rats that have undergone unilateral nephrectomy. Time course evaluation of blood pressure, kidney injury, and renal hemodynamics was performed in the following six groups of animals from weeks 13 to 18: 1) DOCA-treated rats with a solitary kidney (DOCA+S group), 2) placebo-treated rats with a solitary kidney, 3) DOCA-treated control rats with two kidneys (DOCA+C group), 4) placebo-treated control rats with two kidneys, 5) DOCA-treated rats with two kidneys that underwent uninephrectomy (DOCA+UNX8 group), and 6) placebo-treated rats with two kidneys that underwent uninephrectomy. DOCA+S rats demonstrated a significant rise ( P < 0.05) in blood pressure (192 ± 4 mmHg), proteinuria (205 ± 31 mg/24 h), and a decline in glomerular filtration rate (600 ± 42 μl·min−1·g kidney weight−1) relative to the DOCA+UNX8 (173 ± 3 mmHg, 76 ± 26 mg/24 h, and 963 ± 36 μl·min−1·g kidney weight−1) and DOCA+C (154 ± 2 mmHg, 7 ± 1 mg/24 h, and 1,484 ± 121 μl·min−1·g kidney weight−1) groups. Placebo-treated groups showed no significant change among the three groups. An assessment of renal injury markers via real-time PCR/Western blot analysis and histological analysis was concordant with the measured physiological parameters. In summary, congenital solitary kidney rats are highly susceptible to the induction of hypertension compared with uninephrectomized rats, suggesting that low nephron endowment is an important driver of elevated blood pressure, hastening nephron injury through the transmission of elevated systemic blood pressure and thereby accelerating decline in kidney function.

scholarly journals Biliary ductal variations and its clinical implications: a cadaveric study

2017 ◽  
Vol 5 (7) ◽  
pp. 3071
Author(s):  
Priyanka Parmar ◽  
Suresh Kanta Rathee ◽  
SK Dhattarwal ◽  
Sanjay Marwah
Keyword(s):  
Postoperative Complications ◽  
Cystic Duct ◽  
Cadaveric Study ◽  
Clinical Implications ◽  
Long Time ◽  
The Subject

Background: Biliary ductal region being frequently abnormal has been the subject of research since long time for anatomists, surgeons and radiologists as well.Methods: The present study was carried out in the department of Anatomy at PGIMS, Rohtak on 50 specimens of liver taken unblock with associated structures.Results: Accessory hepatic and accessory cystic ducts were observed in 4% cases each.  2% cases exhibited abnormal low fusion of cystic duct with common hepatic duct.Conclusions: These anomalies may add to postoperative complications if ignored. Present study is a step in the direction of creating awareness about these variations among the clinicians.

scholarly journals Clinical case of the treatment of metastatic luminal breast cancer

2021 ◽  
pp. 160-166
Author(s):  
A. F. Nasretdinov ◽  
A. V. Sultanbaev ◽  
K. V. Menshikov ◽  
Sh. I. Musin ◽  
N. I. Sultanbaeva ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Trials ◽  
Hormone Therapy ◽  
Hormone Receptor ◽  
Clinical Case ◽  
Luminal Breast Cancer ◽  
Hormone Receptor Positive ◽  
Long Time ◽  
Visceral Metastases

Hormone therapy currently open up the prospect of long-term, comfortable and relatively low-toxic treatment for patients with hormone receptor – positive advanced breast cancer. For a long time, the presence of visceral metastases prompted oncologists to abandon hormone therapy in favor of cytostatic agents. Now days, even in the presence of visceral metastases, clinical guidelines allow use of modern hormonal therapy in the absence of a visceral crisis. In particular, the so-called CDK 4/6 inhibitors, presented on the Russian market by drugs: palbociclib, ribociclib and abemacyclib, became the drugs that significantly improved the  results of  hormone therapy. Each of  them has demonstrated its effectiveness in  clinical trials; moreover, there are lots of clinical cases demonstrating the benefits of this therapy in real clinical practice. The article presents a clinical case of treatment of advanced hormone receptor-positive breast cancer. The effectiveness of treatment with CDK 4/6 inhibitors has been demonstrated, a comparatively analysed with the data obtained in the course of clinical trials. The analysis of the tactics of treatment of cytomegalovirus infection of the cornea during therapy with ribociclib was carried out. 

Combined urogenital abnormalities of development and the formation of reproductive health in girls

2021 ◽  
Vol 25 (6) ◽  
pp. 99-105
Author(s):  
Yu. Yu. Chebotareva ◽  
G. M. Letifov ◽  
M. A. Rodina
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Reproductive Health ◽  
Tract Infection ◽  
Clinical Case ◽  
Recurrent Urinary Tract Infection ◽  
Practical Importance ◽  
Type I ◽  
Functional Features ◽  
Clinical Cases

BACKGROUND. Anomalies in the development of the uterus and vagina in some cases are combined with defects of the urinary tract. Therefore, the analysis of clinical situations associated with combined urogenital pathology in girls is of current and practical importance.THE AIM: to assess the state of reproductive health in girls with reproductive anomalies, renal agenesis, and other diseases of the urinary tract.PATIENTS AND METHODS. The study was conducted in 5 adolescent girls, including 3 patients with kidney agenesis, 1 patient with dysmetabolic nephropathy and nephroptosis, and 1 patient with recurrent urinary tract infection. In the analysis of clinical cases, the anatomical and functional features of the reproductive system are presented.RESULTS. The first 3 clinical cases are associated with the presence of kidney agenesis in the girl. In 1 clinical case, the clinic of the Mayer-Rokitansky-Kuester-Hauser syndrome (SMRKH) type II, including aplasia of the uterus and vagina and renal malformation, is presented. In clinical case 2, it was shown that modern transabdominal ultrasound examination of the pelvic organs, similar to MRI, can reveal the Herlin-Werner-Wunderlich syndrome. Agenesis of the kidney is one of the manifestations of trisomy of 22 pairs of chromosomes, which was noted in a patient from 3 clinical cases. 4 clinical cases is associated with the fact that kidney pathology, including nephroptosis, dysmetabolic nephropathy, can be combined with impaired sexual development. In 5 clinical case, type I SMRCC was described in a patient with recurrent urinary tract infection.CONCLUSION. Congenital malformations of the female genital organs are a rare pathology that requires special attention. Due to insufficient data concerning the mechanism of development of malformations of the genitourinary system, this problem requires further detailed study.

COVID-19 in Single Kidney Patient

2022 ◽  
Author(s):  
Rahim Raofi ◽  
Yasaman Pourfarid ◽  
Navid Kalani ◽  
Mohsen Hojat
Keyword(s):  
At Risk ◽  
Renal Agenesis ◽  
Solitary Kidney ◽  
Care Plan ◽  
Unilateral Renal Agenesis ◽  
Area Of Interest ◽  
Unique Approach ◽  
Infectious Disease Specialists ◽  
Renal Patient ◽  
Single Kidney

The COVID-19 pandemic has affected all people in the world, especially those at risk of kidney disorders. Early kidney damage in patients born with unilateral renal agenesis (URA) or solitary kidney can happen. These patients are at risk of chronic kidney disease (CKD), high blood pressure, and developing proteinuria. Unilateral renal agenesis is a cause of CKD. Therefore, it is very interesting that observe a unilateral renal Patient that Suffers from COVID-19. Hence, the management of these patients with COVID‐19 is an area of interest, and a unique approach is warranted. A 43-year-old male patient with unilateral renal presented to our hospital for corona disease. The case was discussed between the nephrologists, Infectious disease specialists, and nursing head nurses for a care plan daily. The patient had unilateral renal disease, and COVID-19 could have a detrimental effect on the renal, but renal tests were normal, and the patient recovered without acute renal complications. The treatment of such patients is the need for teamwork contain nephrologists, critical care nurses, and specialists in infectious and tropical diseases. This was a new experience in Iran.

Postoperative Complications due to Injuries of the Urinary Tract as a Result of Vaginal Surgery

1970 ◽  
Vol 37 (6) ◽  
pp. 338-342
Author(s):  
A.H. Papaloucas ◽  
D.A. Haliassos ◽  
S.K. Zervos ◽  
P. Paissios
Keyword(s):  
Urinary Tract ◽  
Postoperative Complications ◽  
Vaginal Surgery
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