scholarly journals Manajemen Logistik Obat Antiretroviral Dalam Program Penanggulangan HIV/AIDS

2020 ◽  
Vol 1 (2) ◽  
pp. 58-69
Author(s):  
Desiderata Jegalus ◽  
Rina Waty Sirait ◽  
Dominirsep O. Dodo ◽  
Yoseph Kendjam
Keyword(s):  
Evaluation System ◽  
Antiretroviral Drugs ◽  
Health Centers ◽  
Logistics Management ◽  
Management Approach ◽  
Logistic Management ◽  
Antiretroviral Drug ◽  
Coordination System ◽  
Management Cycle ◽  
Hiv Aids

One of the points of the HIV AIDS prevention strategy is to increase the availability and affordability of antiretroviral treatment in hospitals or health centers. The emptiness in antiretroviral drugs is a phenomenon that commonly occurs in hospitals or health centers at the district or city level, and Manggarai Regency is one of the districts that experienced this condition from 2013 to 2017. The aim of this study is to explain the situation and the causes of the absence of antiretroviral drugs with a logistic management approach. This type of research is qualitative research. The informants of this study amounted to 8 people from RSUD dr. Ben Mboi, NTT Provincial Health Office, KPAP NTT and KPAD Manggarai. Data collection will take place from February to March 2018. The results are: Antiretroviral drug planning using consumption methods; budgeting and procurement of antiretroviral drugs by the Indonesian Ministry of Health; the storage of antiretroviral drugs is carried out according to the current standards for the storage of medicines; distribution of antiretroviral drugs from the provinces with expeditions and from hospitals to PLWHA with individual prescriptions that are represented by one person; the elimination of antiretroviral drugs was never performed; control of antiretroviral drugs that are adapted to the schedule of taking medication; cause of the absence of antiretroviral drugs due to the lack of specialized staff administering antiretroviral drugs in hospital pharmacies. Management of antiretroviral drugs in Manggarai Regency runs accordingly the logistics management cycle, but there are still some issues that accompany this process. Issues in question include insufficient human resources in terms of quantity and quality, non-procedural implementation and a weak coordination system. It is recommended that improvements be made to the logistical management process of antiretroviral drugs in hospitals, as well as strengthening the coordination and evaluation system of all parties involved in the logistics management of antiretroviral drugs.

Antiretroviral uptake in Australia: medical, attitudinal and cultural correlates

1998 ◽  
Vol 9 (10) ◽  
pp. 579-586 ◽  
Author(s):  
Douglas M Ezzy ◽  
Michael R Bartos ◽  
Richard O De Visser ◽  
Doreen A Rosenthal
Keyword(s):  
Logistic Regression ◽  
Antiretroviral Drugs ◽  
Cd4 T Cell ◽  
People Living With Hiv ◽  
Antiretroviral Drug ◽  
Living With Hiv ◽  
Self Administered Questionnaire ◽  
Cd4 T Cell Count ◽  
Cessation Of Treatment ◽  
Hiv Aids

The objective of this study was to describe the medical, attitudinal and cultural correlates of antiretroviral uptake amongst people living with HIV/AIDS (PLWHA) in Australia. Stratified purposive sampling produced a sample of 925 PLWHA, which represents 8.3% of the current population of PLWHA in Australia. Respondents completed a self-administered questionnaire which revealed that 78% of respondents were using antiretroviral drugs for HIV/AIDS. Logistic regression revealed that PLWHA were more likely to use antiretroviral drugs if they had more favourable attitudes toward antiretroviral drugs, if they had been diagnosed with an AIDS-defining illness, and if they had ever had a CD4/T-cell count below 400 copies/ml blood. Women were less likely than men to use antiretroviral drugs, and logistic regression revealed different predictors of antiretroviral drug use amongst men and women. Given the importance of attitudes toward antiretroviral drugs, it is likely that if the current confidence in antiretroviral drugs were to change, this would be reflected in an equally rapid cessation of treatment amongst many PLWHA.

PERAN WARGA PEDULI AIDS CAHAYA CARE TUREN DALAM MENINGKATKAN KUALITAS HIDUP ODHA

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Tri Nurhudi Sasono
Keyword(s):  
Quality Of Life ◽  
Antiretroviral Drugs ◽  
P Value ◽  
People Living With Hiv ◽  
Purposive Sampling ◽  
Significant Difference ◽  
Development Goals ◽  
Living With Hiv ◽  
Hiv Aids

Abstract : Indicator of the health welfare through Sustanable Development Goals (SDGs) is to reduce the incidence of HIV-AIDS, decrease the rate of the epidemic and maintain the quality of life of people living with HIV-AIDS (PLWHA). Trend cases of HIV-AIDS is the most recent spread among people, especially housewives. In Malang until 2015 found 278 Housewife of 409 cases of AIDS. The prevalence of HIV-AIDS in Malang Regency is ranked second after Surabaya city in East Java. For the importance of public participation and citizen care AIDS Cahaya Care Turen take responsibility for the condition. Determination Rule Goverment number 2 2015 year on the Participation of the community response to HIV-AIDS in Malang as a legal rule. Concerned Citizens activities AIDS (WPA). WPA Cahaya Care Turen is increases HIV risk and quality of life PLWHA. The purpose of this study was to determine the role of Citizens AIDS Cahaya Care Quality of Care Turen against people living with HIV in Puskesmas Turen Malang. The study design using a quasi-experimental, with purposive sampling using a sampling technique. Total number of research subjects 23. Based on test results obtained with the Wilcoxon p value <0.005, which means that there is a significant difference before and after PLWHA joining participated in the WPA Cahaya Care Turen. The conclusion of this study is WPA activities involving people living with HIV and at risk groups can optimize compliance with antiretroviral drugs that have an impact on improving the quality of life of PLHIV. Suggestions in this research is done WPA Program activities are structured and ongoing cross-sector in order to improve the quality of life and empower PLWHA.Keywords : WPA Cahaya Care Turen, Quality of life, PLWHA Abstrak : Salah satu indikator kesejahteraan kesehatan melalui Sustanable Development Goals (SDGs) adalah menekan angka kejadian HIV-AIDS, menurunkan laju epidemik dan mempertahankan kualitas hidup Orang dengan HIV-AIDS (ODHA). Trend kasus HIV-AIDS terkini terbanyak adalah menjangkit dikalangan masyarakat khususnya pada ibu rumah tangga. Kabupaten Malang sampai dengan tahun 2015 ditemukan 278 Ibu Rumah Tangga dari 409 kasus AIDS. Prevalensi HIV-AIDS di Kabupaten Malang ini merupakan peringkat kedua di Jawa Timur setelah Kota Surabaya. Untuk itu pentingnya peran serta masyarakat dan warga peduli AIDS Cahaya Care Turen ikut bertanggung jawab terhadap kondisi tersebut. Penetapan Peraturan Bupati Malang no.2 th.2015 tentang Peran serta masyarakat penanggulangan HIV-AIDS di Kabupaten Malang diharapkan dapat mengurangi risiko penularan HIV dan meningkatkan kualitas hidup ODHA. Tujuan dari penelitian ini adalah untuk mengetahui Peran Warga Peduli AIDS Cahaya Care Turen terhadap Kualitas ODHA Di Wilayah Kerja Puskesmas Turen Kabupaten Malang. Desain penelitian menggunakan quasi eksperimen, dengan teknik sampling menggunakan purposive sampling. Jumlah subyek penelitian sejumlah 23. Berdasarkan hasil uji dengan Wilcoxon didapatkan nilai p value < 0.005 yang berarti bahwa terdapat perbedaan bermakna sebelum dan sesudah ODHA bergabung mengikuti kegiatan WPA Cahaya Care Turen. Kesimpulan dalam penelitian ini adalah kegiatan WPA dengan melibatkan ODHA dan kelompok beresiko dapat mengoptimalkan kepatuhan obat ART sehingga berdampak terhadap peningkatan kualitas hidup ODHA. Saran dalam penelitian ini adalah dilakukannya Program kegiatan WPA yang terstruktur dan berkesinambungan lintas sektor guna meningkatkan kualitas hidup dan memberdayakan ODHA.     Kata kunci : WPA Cahaya Care Turen, kualitas hidup, ODHA

Nanoparticles and Its Implications in HIV/AIDS Therapy

2020 ◽  
Vol 17 (4) ◽  
pp. 448-456 ◽  
Author(s):  
Victor B. Oti
Keyword(s):  
Direct Injection ◽  
Oral Intake ◽  
Public Health Problem ◽  
Antiretroviral Drugs ◽  
The Body ◽  
Viral Agent ◽  
Treatment And Prevention ◽  
Prevention And Treatment ◽  
Hiv Aids

The use of Antiretroviral drugs in treating HIV/ AIDS patients has enormously increased their life spans with serious disadvantages. The virus infection still remains a public health problem worldwide with no cure and vaccine for the viral agent until now. The use of nanoparticles (NPs) for the treatment and prevention of HIV/AIDS is an emerging technology of the 21st century. NPs are solid and colloid particles with 10 nm to <1000 nm size range; although, less than 200 nm is the recommended size for nanomedical usage. There are NPs with therapeutic capabilities such as liposomes, micelles, dendrimers and nanocapsules. The particle enters the body mainly via oral intake, direct injection and inhalation. It has been proven to have potentials of advancing the prevention and treatment of the viral agent. Certain NPs have been shown to have selftherapeutic activity for the virus in vitro. Strategies that are novel are emerging which can be used to improve nanotechnology, such as genetic treatment and immunotherapy. In this review, nanoparticles, the types and its characteristics in drug delivery were discussed. The light was furthermore shed on its implications in the prevention and treatment of HIV/AIDS.

scholarly journals Anti-HIV and Anti-Candidal Effects of Methanolic Extract from Heteropterys brachiata

2021 ◽  
Vol 18 (14) ◽  
pp. 7270
Author(s):  
Maira Huerta-Reyes ◽  
Luis O. Sánchez-Vargas ◽  
Getsemaní S. Villanueva-Amador ◽  
Luis A. Gaitán-Cepeda
Keyword(s):  
Standardized Test ◽  
Methanolic Extract ◽  
Colorimetric Method ◽  
Antiretroviral Drugs ◽  
Comprehensive Treatment ◽  
Potential Candidate ◽  
Test Protocol ◽  
Aids Patients ◽  
Anti Hiv ◽  
Hiv Aids

Nowadays, the HIV pandemic is far from controlled. HIV+/AIDS patients show a serious risk of developing resistance to HIV antiretroviral drugs and to be orally colonized by albicans and non-albicans Candida strains resistant to antifungals. As a consequence, new drugs that possess anti-candidal and anti-HIV effects would represent an alternative in the comprehensive treatment of HIV+/AIDS patients. The present study evaluates the possible anti-HIV and anti-Candida effects of a methanolic extract from Heteropterys brachiata (Hb MeOH), an American tropical plant. The anti-HIV effect of Hb MeOH was tested using a non-radioactive colorimetric method (Lenti RT® Activity Assay; Cavidi Tech) that uses reverse transcriptase of HIV-1 enzyme as enzymatic target. The anti-candidal effect of HbMeOH extract was evaluated by following a standardized test protocol of microdilution for yeast using the Candida albicans strain ATCC® 90028. The Hb MeOH at 1 mg/mL concentration shows 38.5% RT-HIV inhibition, while Hb MeOH at 10 mg/mL concentration produced 98% C. albicans growth inhibition. Our findings show that the Hb MeOH possesses a strong anti-candidal activity and moderate anti-HIV effect and suggests that the plant extract could be considered as a potential candidate for HIV/AIDS treatment.

scholarly journals Antiretroviral drugs and acute pancreatitis in HIV/AIDS patients: is there any association? A literature review

2014 ◽  
Vol 12 (1) ◽  
pp. 112-119 ◽  
Author(s):  
Natalia Mejias Oliveira ◽  
Felipe Augusto Yamauti Ferreira ◽  
Raquel Yumi Yonamine ◽  
Ethel Zimberg Chehter
Keyword(s):  
Acute Pancreatitis ◽  
Antiretroviral Therapy ◽  
Opportunistic Infections ◽  
Case Reports ◽  
Case Series ◽  
Antiretroviral Drugs ◽  
Pancreatic Involvement ◽  
Frequent Event ◽  
Hiv Seropositive ◽  
Hiv Aids

In HIV-seropositive individuals, the incidence of acute pancreatitis may achieve 40% per year, higher than the 2% found in the general population. Since 1996, when combined antiretroviral therapy, known as HAART (highly active antiretroviral therapy), was introduced, a broad spectrum of harmful factors to the pancreas, such as opportunistic infections and drugs used for chemoprophylaxis, dropped considerably. Nucleotide analogues and metabolic abnormalities, hepatic steatosis and lactic acidosis have emerged as new conditions that can affect the pancreas. To evaluate the role of antiretroviral drugs to treat HIV/AIDS in a scenario of high incidence of acute pancreatitis in this population, a systematic review was performed, including original articles, case reports and case series studies, whose targets were HIV-seropositive patients that developed acute pancreatitis after exposure to any antiretroviral drugs. This association was confirmed after exclusion of other possible etiologies and/or a recurrent episode of acute pancreatitis after re-exposure to the suspected drug. Zidovudine, efavirenz, and protease inhibitors are thought to lead to acute pancreatitis secondary to hyperlipidemia. Nucleotide reverse transcriptase inhibitors, despite being powerful inhibitors of viral replication, induce a wide spectrum of side effects, including myelotoxicity and acute pancreatitis. Didanosine, zalcitabine and stavudine have been reported as causes of acute and chronic pancreatitis. They pose a high risk with cumulative doses. Didanosine with hydroxyurea, alcohol or pentamidine are additional risk factors, leading to lethal pancreatitis, which is not a frequent event. In addition, other drugs used for prophylaxis of AIDS-related opportunistic diseases, such as sulfamethoxazole-trimethoprim and pentamidine, can produce necrotizing pancreatitis. Despite comorbidities that can lead to pancreatic involvement in the HIV/AIDS population, antiretroviral drug-induced pancreatitis should always be considered in the diagnosis of patients with abdominal pain and elevated pancreatic enzymes.

scholarly journals PERILAKU PERAWAT TERHADAP ORANG DENGAN HIV/AIDS DI RUMAH SAKIT DAN PUSKESMAS

2011 ◽  
Vol 14 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Agung Waluyo ◽  
Prima Agustia Nova ◽  
Chiyar Edison
Keyword(s):  
Public Health ◽  
Mixed Method ◽  
Religious Beliefs ◽  
Educational Background ◽  
Health Centers ◽  
Hiv Stigma ◽  
Hiv Knowledge ◽  
Correlative Study ◽  
Hiv Aids

AbstrakDiskriminasi dan stigmatisasi terhadap ODHA telah dilaporkan terjadi di beberapa rumah sakit di Jakarta.\Tujuan dari penelitianini adalah untuk mengetahui pengetahuan HIV, keyakinan agama, dan persepsi perawat tentang HIV-stigma mempengaruhisikap terhadap ODHA. Studi deskriptif korelatif dengan menggunakan mix method dalam pengumpulan data yang digunakan.Sampel 326 perawat yang merawat ODHA dari 4 rumah sakit dan 5 pusat kesehatan masyarakat di Jakarta, direkrut menggunakanteknik convenience. Hasilnya menunjukkan bahwa sikap terhadap ODHA secara signifikan berbeda antara perawat yang memilikipelatihan HIV dan yang tidak (p= 0,001; α= 0,05), bekerja di rumah sakit dan Puskesmas (p= 0,01; α= 0,05), perawat dengan latarbelakang pendidikan yang berbeda (p= 0,05; α= 0,05), dan perawat yang merasa kompeten atau tidak kompeten untuk merawatODHA (p= 0,001; α= 0,05). Peningkatan pengetahuan HIV diperlukan perawat untuk menurunkan stigma pasien ODHA.Kata kunci: Indonesia, perawat, stigma HIVAbstractDiscrimination and stigmatization towards PLWH has been documented in some hospitals in Jakarta. The purpose of thisstudy is to determine the extent to which the nurses’ HIV knowledge, religious beliefs, and their perception of HIV-stigmaaffect their attitudes toward HIV/AIDS. Descriptive correlative study with using mixed method in collecting data was used. Aconvenience sample of 326 nurses who are working with PLWH from 4 hospitals and 5 public health centers in Jakarta,Indonesia were recruited. The result shows that attitudes toward PLWH were significantly different between nurses who hadHIV training and not (p= 0.001; α= 0,05), works in hospitals and public health centers (p= 0.01; α= 0.05), nurses withdifferent educational background (p= 0.05; α= 0.05), and nurses who perceived that they are competent or not competent tocare PLWH (p= 0.001; α= 0.05). Increase of HIV knowledge required nurses to reduce PLWH patient’s stigma.Keywords: Indonesia, Nurses, HIV-stigma

scholarly journals Maternal and infant health is protected by antiretroviral drug strategies that preserve breastfeeding by HIV-positive women

2012 ◽  
Vol 13 (1) ◽  
Author(s):  
Louise Kuhn
Keyword(s):  
South African ◽  
Infant Formula ◽  
Infant Health ◽  
Antiretroviral Drugs ◽  
Hiv Positive ◽  
Infant Survival ◽  
Department Of Health ◽  
Hiv Positive Women ◽  
Antiretroviral Drug ◽  
Maternal And Infant Health

The South African Department of Health is justified in withdrawing support for free infant formula. By so doing, it recognises that any intervention that might detract from breast feeding poses a serious threat to infant survival. Since evidence is now strong that antiretroviral drugs used during lactation prevent transmission of infection from a seropositive mother, strategies that promote breastfeeding can now be recommended for enhancing the health of mothers and infants.

scholarly journals The effect of logistics management, supply chain facilities and competitive storage costs on the use of warehouse financing of agricultural products

2021 ◽  
Vol 9 (2) ◽  
pp. 457-464 ◽  
Author(s):  
Paramita Prananingtyas ◽  
Siti Zulaekhah
Keyword(s):  
Regression Analysis ◽  
Supply Chain ◽  
Random Sampling ◽  
Sampling Method ◽  
Linear Regression Analysis ◽  
Agricultural Products ◽  
Logistics Management ◽  
Central Java ◽  
Logistic Management ◽  
Study Results

This study seeks to analyze the effect of logistics management carried out by warehouse operators, the facilities and access provided to support storage, and the competitiveness of storage costs on the use of warehouse financing by suppliers in Central Java, Indonesia. The sampling method was purposive random sampling. The numbers of respondents involved in this study were 120 suppliers and farmers producing first-rate agricultural products and who are users of warehouse receipts in the Central Java region. By using linear regression analysis with assistance, the study results found that the variables of logistic management, facilities and supply chain access as well as competitive storage costs have positive and significant effects on the use of warehousing financing by suppliers and farmers who use public warehousing. This result confirms that the more precisely warehousing is managed, the higher the level of trust of users involved in the logistics business and supply chain of agricultural products to use additional services in the form of warehouse receipts to support the sustainability of agricultural businesses.

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