scholarly journals Machine Learning Framework to Predict Chronic Kidney Disease using Ensemble Algorithm

Chronic Kidney Disease (CKD) is a worldwide concern that influences roughly 10% of the grown-up population on the world. For most of the people the early diagnosis of CKD is often not possible. Therefore, the utilization of present-day Computer aided supported strategies is important to help the conventional CKD finding framework to be progressively effective and precise. In this project, six modern machine learning techniques namely Multilayer Perceptron Neural Network, Support Vector Machine, Naïve Bayes, K-Nearest Neighbor, Decision Tree, Logistic regression were used and then to enhance the performance of the model Ensemble Algorithms such as ADABoost, Gradient Boosting, Random Forest, Majority Voting, Bagging and Weighted Average were used on the Chronic Kidney Disease dataset from the UCI Repository. The model was tuned finely to get the best hyper parameters to train the model. The performance metrics used to evaluate the model was measured using Accuracy, Precision, Recall, F1-score, Mathew`s Correlation Coefficient and ROC-AUC curve. The experiment was first performed on the individual classifiers and then on the Ensemble classifiers. The ensemble classifier like Random Forest and ADABoost performed better with 100% Accuracy, Precision and Recall when compared to the individual classifiers with 99.16% accuracy, 98.8% Precision and 100% Recall obtained from Decision Tree Algorithm

2021 ◽  
Vol 12 (2) ◽  
pp. 28-55
Author(s):  
Fabiano Rodrigues ◽  
Francisco Aparecido Rodrigues ◽  
Thelma Valéria Rocha Rodrigues

Este estudo analisa resultados obtidos com modelos de machine learning para predição do sucesso de startups. Como proxy de sucesso considera-se a perspectiva do investidor, na qual a aquisição da startup ou realização de IPO (Initial Public Offering) são formas de recuperação do investimento. A revisão da literatura aborda startups e veículos de financiamento, estudos anteriores sobre predição do sucesso de startups via modelos de machine learning, e trade-offs entre técnicas de machine learning. Na parte empírica, foi realizada uma pesquisa quantitativa baseada em dados secundários oriundos da plataforma americana Crunchbase, com startups de 171 países. O design de pesquisa estabeleceu como filtro startups fundadas entre junho/2010 e junho/2015, e uma janela de predição entre junho/2015 e junho/2020 para prever o sucesso das startups. A amostra utilizada, após etapa de pré-processamento dos dados, foi de 18.571 startups. Foram utilizados seis modelos de classificação binária para a predição: Regressão Logística, Decision Tree, Random Forest, Extreme Gradiente Boosting, Support Vector Machine e Rede Neural. Ao final, os modelos Random Forest e Extreme Gradient Boosting apresentaram os melhores desempenhos na tarefa de classificação. Este artigo, envolvendo machine learning e startups, contribui para áreas de pesquisa híbridas ao mesclar os campos da Administração e Ciência de Dados. Além disso, contribui para investidores com uma ferramenta de mapeamento inicial de startups na busca de targets com maior probabilidade de sucesso.   


Symmetry ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 403
Author(s):  
Muhammad Waleed ◽  
Tai-Won Um ◽  
Tariq Kamal ◽  
Syed Muhammad Usman

In this paper, we apply the multi-class supervised machine learning techniques for classifying the agriculture farm machinery. The classification of farm machinery is important when performing the automatic authentication of field activity in a remote setup. In the absence of a sound machine recognition system, there is every possibility of a fraudulent activity taking place. To address this need, we classify the machinery using five machine learning techniques—K-Nearest Neighbor (KNN), Support Vector Machine (SVM), Decision Tree (DT), Random Forest (RF) and Gradient Boosting (GB). For training of the model, we use the vibration and tilt of machinery. The vibration and tilt of machinery are recorded using the accelerometer and gyroscope sensors, respectively. The machinery included the leveler, rotavator and cultivator. The preliminary analysis on the collected data revealed that the farm machinery (when in operation) showed big variations in vibration and tilt, but observed similar means. Additionally, the accuracies of vibration-based and tilt-based classifications of farm machinery show good accuracy when used alone (with vibration showing slightly better numbers than the tilt). However, the accuracies improve further when both (the tilt and vibration) are used together. Furthermore, all five machine learning algorithms used for classification have an accuracy of more than 82%, but random forest was the best performing. The gradient boosting and random forest show slight over-fitting (about 9%), but both algorithms produce high testing accuracy. In terms of execution time, the decision tree takes the least time to train, while the gradient boosting takes the most time.


2021 ◽  
Vol 44 (4) ◽  
pp. 1-12
Author(s):  
Ratchainant Thammasudjarit ◽  
Punnathorn Ingsathit ◽  
Sigit Ari Saputro ◽  
Atiporn Ingsathit ◽  
Ammarin Thakkinstian

Background: Chronic kidney disease (CKD) takes huge amounts of resources for treatments. Early detection of patients by risk prediction model should be useful in identifying risk patients and providing early treatments. Objective: To compare the performance of traditional logistic regression with machine learning (ML) in predicting the risk of CKD in Thai population. Methods: This study used Thai Screening and Early Evaluation of Kidney Disease (SEEK) data. Seventeen features were firstly considered in constructing prediction models using logistic regression and 4 MLs (Random Forest, Naïve Bayes, Decision Tree, and Neural Network). Data were split into train and test data with a ratio of 70:30. Performances of the model were assessed by estimating recall, C statistics, accuracy, F1, and precision. Results: Seven out of 17 features were included in the prediction models. A logistic regression model could well discriminate CKD from non-CKD patients with the C statistics of 0.79 and 0.78 in the train and test data. The Neural Network performed best among ML followed by a Random Forest, Naïve Bayes, and a Decision Tree with the corresponding C statistics of 0.82, 0.80, 0.78, and 0.77 in training data set. Performance of these corresponding models in testing data decreased about 5%, 3%, 1%, and 2% relative to the logistic model by 2%. Conclusions: Risk prediction model of CKD constructed by the logit equation may yield better discrimination and lower tendency to get overfitting relative to ML models including the Neural Network and Random Forest.  


Author(s):  
Kallu Samatha ◽  
Muppidi Rohitha Reddy ◽  
Pattan Faizal Khan ◽  
Rayapati Akhil Chowdary ◽  
P.V.R.D Prasada Rao

Kidney diseases are increasing day by day among people. It is becoming a major health issue around the world. Not maintaining proper food habits and drinking less amount of water are one of the major reasons that contribute this condition. With this, it has become necessary to build up a system to foresee Chronic Kidney Diseases precisely. Here, we have proposed an approach for real time kidney disease prediction. Our aim is to find the best and efficient machine learning (ML) application that can effectively recognize and predict the condition of chronic kidney disease. We have used the data from UCI machine learning repository. In this work, five important machine learning classification techniques were considered for predicting chronic kidney disease which are KNN, Logistic Regression, Random Forest Classifier, SVM and Decision Tree Classifier. In this process, the data has been divided into two sections. In one section train dataset got trained and another section got evaluated by test dataset. The analysis results show that Decision Tree Classifier and Logistic Regression algorithms achieved highest performance than the other classifiers, obtaining the accuracy of 98.75% followed by random Forest, which stands at 97.5%.


Diagnostics ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2267
Author(s):  
Nakib Hayat Chowdhury ◽  
Mamun Bin Ibne Reaz ◽  
Fahmida Haque ◽  
Shamim Ahmad ◽  
Sawal Hamid Md Ali ◽  
...  

Chronic kidney disease (CKD) is one of the severe side effects of type 1 diabetes mellitus (T1DM). However, the detection and diagnosis of CKD are often delayed because of its asymptomatic nature. In addition, patients often tend to bypass the traditional urine protein (urinary albumin)-based CKD detection test. Even though disease detection using machine learning (ML) is a well-established field of study, it is rarely used to diagnose CKD in T1DM patients. This research aimed to employ and evaluate several ML algorithms to develop models to quickly predict CKD in patients with T1DM using easily available routine checkup data. This study analyzed 16 years of data of 1375 T1DM patients, obtained from the Epidemiology of Diabetes Interventions and Complications (EDIC) clinical trials directed by the National Institute of Diabetes, Digestive, and Kidney Diseases, USA. Three data imputation techniques (RF, KNN, and MICE) and the SMOTETomek resampling technique were used to preprocess the primary dataset. Ten ML algorithms including logistic regression (LR), k-nearest neighbor (KNN), Gaussian naïve Bayes (GNB), support vector machine (SVM), stochastic gradient descent (SGD), decision tree (DT), gradient boosting (GB), random forest (RF), extreme gradient boosting (XGB), and light gradient-boosted machine (LightGBM) were applied to developed prediction models. Each model included 19 demographic, medical history, behavioral, and biochemical features, and every feature’s effect was ranked using three feature ranking techniques (XGB, RF, and Extra Tree). Lastly, each model’s ROC, sensitivity (recall), specificity, accuracy, precision, and F-1 score were estimated to find the best-performing model. The RF classifier model exhibited the best performance with 0.96 (±0.01) accuracy, 0.98 (±0.01) sensitivity, and 0.93 (±0.02) specificity. LightGBM performed second best and was quite close to RF with 0.95 (±0.06) accuracy. In addition to these two models, KNN, SVM, DT, GB, and XGB models also achieved more than 90% accuracy.


Author(s):  
Ms. Kallu Samatha ◽  
◽  
Ms. Muppidi Rohitha Reddy ◽  
Mr. Pattan Faizal Khan ◽  
Mr. Rayapati Akhil Chowdary ◽  
...  

Kidney diseases are increasing day by day among people. It is becoming a major health issue around the world. Not maintaining proper food habits and drinking less amount of water are one of the major reasons that contribute this condition. With this, it has become necessary to build up a system to foresee Chronic Kidney Diseases precisely. Here, we have proposed an approach for real time kidney disease prediction. Our aim is to find the best and efficient machine learning (ML) application that can effectively recognize and predict the condition of chronic kidney disease. We have used the data from UCI machine learning repository. In this work, five important machine learning classification techniques were considered for predicting chronic kidney disease which are KNN, Logistic Regression, Random Forest Classifier, SVM and Decision Tree Classifier. In this process, the data has been divided into two sections. In one section train dataset got trained and another section got evaluated by test dataset. The analysis results show that Decision Tree Classifier and Logistic Regression algorithms achieved highest performance than the other classifiers, obtaining the accuracy of 98.75% followed by random Forest, which stands at 97.5%.


Author(s):  
Komal Kumar N ◽  
R. Lakshmi Tulasi ◽  
Vigneswari D

<span lang="EN-US">Chronic Kidney Disease (CKD) is a type of lifelong kidney disease that leads to the gradual loss of kidney function over time; the main function of the kidney is to filter the wastein the human body. When the kidney malfunctions, the wastes accumulate in our body leading to complete failure. Machine learning algorithms can be used in prediction of the kidney disease at early stages by analyzing the symptoms. The aim of this paper is to propose an ensemble learning technique for predicting Chronic Kidney Disease (CKD). We propose a new hybrid classifier called as ABC4.5, which is ensemble learning for predicting Chronic Kidney Disease (CKD). The proposed hybrid classifier is compared with the machine learning classifiers such as Support Vector Machine (SVM), Decision Tree (DT), C4.5, Particle Swarm Optimized Multi Layer Perceptron (PSO-MLP). The proposed classifier accurately predicts the occurrences of kidney disease by analysis various medical factors. The work comprises of two stages, the first stage consists of obtaining weak decision tree classifiers from C4.5 and in the second stage, the weak classifiers are added to the weighted sum to represent the final output for improved performance of the classifier.</span>


2021 ◽  
pp. 1098612X2110012
Author(s):  
Jade Renard ◽  
Mathieu R Faucher ◽  
Anaïs Combes ◽  
Didier Concordet ◽  
Brice S Reynolds

Objectives The aim of this study was to develop an algorithm capable of predicting short- and medium-term survival in cases of intrinsic acute-on-chronic kidney disease (ACKD) in cats. Methods The medical record database was searched to identify cats hospitalised for acute clinical signs and azotaemia of at least 48 h duration and diagnosed to have underlying chronic kidney disease based on ultrasonographic renal abnormalities or previously documented azotaemia. Cases with postrenal azotaemia, exposure to nephrotoxicants, feline infectious peritonitis or neoplasia were excluded. Clinical variables were combined in a clinical severity score (CSS). Clinicopathological and ultrasonographic variables were also collected. The following variables were tested as inputs in a machine learning system: age, body weight (BW), CSS, identification of small kidneys or nephroliths by ultrasonography, serum creatinine at 48 h (Crea48), spontaneous feeding at 48 h (SpF48) and aetiology. Outputs were outcomes at 7, 30, 90 and 180 days. The machine-learning system was trained to develop decision tree algorithms capable of predicting outputs from inputs. Finally, the diagnostic performance of the algorithms was calculated. Results Crea48 was the best predictor of survival at 7 days (threshold 1043 µmol/l, sensitivity 0.96, specificity 0.53), 30 days (threshold 566 µmol/l, sensitivity 0.70, specificity 0.89) and 90 days (threshold 566 µmol/l, sensitivity 0.76, specificity 0.80), with fewer cats still alive when their Crea48 was above these thresholds. A short decision tree, including age and Crea48, predicted the 180-day outcome best. When Crea48 was excluded from the analysis, the generated decision trees included CSS, age, BW, SpF48 and identification of small kidneys with an overall diagnostic performance similar to that using Crea48. Conclusions and relevance Crea48 helps predict short- and medium-term survival in cats with ACKD. Secondary variables that helped predict outcomes were age, CSS, BW, SpF48 and identification of small kidneys.


2021 ◽  
Author(s):  
Jamal Ahmadov

Abstract The Tuscaloosa Marine Shale (TMS) formation is a clay- and liquid-rich emerging shale play across central Louisiana and southwest Mississippi with recoverable resources of 1.5 billion barrels of oil and 4.6 trillion cubic feet of gas. The formation poses numerous challenges due to its high average clay content (50 wt%) and rapidly changing mineralogy, making the selection of fracturing candidates a difficult task. While brittleness plays an important role in screening potential intervals for hydraulic fracturing, typical brittleness estimation methods require the use of geomechanical and mineralogical properties from costly laboratory tests. Machine Learning (ML) can be employed to generate synthetic brittleness logs and therefore, may serve as an inexpensive and fast alternative to the current techniques. In this paper, we propose the use of machine learning to predict the brittleness index of Tuscaloosa Marine Shale from conventional well logs. We trained ML models on a dataset containing conventional and brittleness index logs from 8 wells. The latter were estimated either from geomechanical logs or log-derived mineralogy. Moreover, to ensure mechanical data reliability, dynamic-to-static conversion ratios were applied to Young's modulus and Poisson's ratio. The predictor features included neutron porosity, density and compressional slowness logs to account for the petrophysical and mineralogical character of TMS. The brittleness index was predicted using algorithms such as Linear, Ridge and Lasso Regression, K-Nearest Neighbors, Support Vector Machine (SVM), Decision Tree, Random Forest, AdaBoost and Gradient Boosting. Models were shortlisted based on the Root Mean Square Error (RMSE) value and fine-tuned using the Grid Search method with a specific set of hyperparameters for each model. Overall, Gradient Boosting and Random Forest outperformed other algorithms and showed an average error reduction of 5 %, a normalized RMSE of 0.06 and a R-squared value of 0.89. The Gradient Boosting was chosen to evaluate the test set and successfully predicted the brittleness index with a normalized RMSE of 0.07 and R-squared value of 0.83. This paper presents the practical use of machine learning to evaluate brittleness in a cost and time effective manner and can further provide valuable insights into the optimization of completion in TMS. The proposed ML model can be used as a tool for initial screening of fracturing candidates and selection of fracturing intervals in other clay-rich and heterogeneous shale formations.


2022 ◽  
pp. ASN.2021040538
Author(s):  
Arthur M. Lee ◽  
Jian Hu ◽  
Yunwen Xu ◽  
Alison G. Abraham ◽  
Rui Xiao ◽  
...  

BackgroundUntargeted plasma metabolomic profiling combined with machine learning (ML) may lead to discovery of metabolic profiles that inform our understanding of pediatric CKD causes. We sought to identify metabolomic signatures in pediatric CKD based on diagnosis: FSGS, obstructive uropathy (OU), aplasia/dysplasia/hypoplasia (A/D/H), and reflux nephropathy (RN).MethodsUntargeted metabolomic quantification (GC-MS/LC-MS, Metabolon) was performed on plasma from 702 Chronic Kidney Disease in Children study participants (n: FSGS=63, OU=122, A/D/H=109, and RN=86). Lasso regression was used for feature selection, adjusting for clinical covariates. Four methods were then applied to stratify significance: logistic regression, support vector machine, random forest, and extreme gradient boosting. ML training was performed on 80% total cohort subsets and validated on 20% holdout subsets. Important features were selected based on being significant in at least two of the four modeling approaches. We additionally performed pathway enrichment analysis to identify metabolic subpathways associated with CKD cause.ResultsML models were evaluated on holdout subsets with receiver-operator and precision-recall area-under-the-curve, F1 score, and Matthews correlation coefficient. ML models outperformed no-skill prediction. Metabolomic profiles were identified based on cause. FSGS was associated with the sphingomyelin-ceramide axis. FSGS was also associated with individual plasmalogen metabolites and the subpathway. OU was associated with gut microbiome–derived histidine metabolites.ConclusionML models identified metabolomic signatures based on CKD cause. Using ML techniques in conjunction with traditional biostatistics, we demonstrated that sphingomyelin-ceramide and plasmalogen dysmetabolism are associated with FSGS and that gut microbiome–derived histidine metabolites are associated with OU.


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