POTENSI METABOLIT SEKUNDER DARI JAMUR YANG BERASOSIASI DENGAN SPONS LAUT SEBAGAI SUMBER SENYAWA ANTIKANKER

2021 ◽  
pp. 553-566
Author(s):  
Iqbal A. Fitriyanto ◽  
Muhammad Hasan Bashari ◽  
Eko Fuji Ariyanto
Keyword(s):  
Aspergillus Sp

Beban kesehatan yang ditimbulkan akibat kanker terus meningkat seiring dengan morbiditas dan mortalitas yang nyata baik di negara maju maupun berkembang. Jamur laut merupakan sumber metabolit sekunder yang berguna untuk tujuan penemuan obat. Sejumlah senyawa metabolit yang dihasilkan oleh jamur laut telah menunjukkan efek antikanker kuat. Metabolit Cytochalasin K yang dihasilkan jamur Arthrinium arundinis ZSDS1-F3 yang diisolasi dari spons laut Phakellia fusca memiliki aktivitas sitotoksik terhadap lini sel K562, A549, Huh-7, H1975, HL60, Hela, dan MOLT-4. Metabolit Disydonol A yang diproduksi oleh jamur Aspergillus sp. yang diisolasi dari spons laut Xestospongia testudinaria memiliki aktivitas sitotoksik terhadap lini sel HepG-2 and Caski. Metabolit Marilines A1 dan A2 yang dihasilkan oleh jamur Stachylidium sp. yang diisolasi dari spons laut Callyspongia cf. C. flammea memiliki aktivitas sitotoksik terhadap lini sel HLE. Dalam ulasan ini, kami menyoroti beberapa jamur yang berasal dari laut dengan metabolit yang dapat memodulasi aktivitas beberapa enzim yang berperan penting pada pertumbuhan dan metastasis sel tumor.

Search for anti-dengue secondary metabolites from two Diospyros endophytes, Aspergillus sp. and Phomopsis sp

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
LA Peyrat ◽  
V Eparvier ◽  
C Eydoux ◽  
JC Guillemot ◽  
D Stien ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Aspergillus Sp

IDENTIFIKASI JENIS JAMUR PATOGEN UNTUK PENGENDALIAN RAYAP TANAH Coptotermes sp.

PERENNIAL ◽  
2010 ◽  
Vol 6 (1) ◽  
pp. 33
Author(s):  
Astuti Arif ◽  
. Syahidah ◽  
Sitti Nuraeni
Keyword(s):  
Key Words ◽  
Pathogenic Fungi ◽  
Wide Distribution ◽  
Subterranean Termite ◽  
The World ◽  
Identification Of Fungi ◽  
Screening And Identification ◽  
Termite Attack ◽  
Penicillium Brevicompactum ◽  
Aspergillus Sp

Fungi have a great diversity and wide distribution at the world. It can be used as the alternative technology for controlling of subterranean termite attack, particularly genus Coptotermes knowned as the wooden destructive organism, by using entomophatogenic fungi. For the purpose of the study, several isolate sources were taken from some locations. The results show that eight numbers of pathogenic fungi was founded by screening and identification of fungi taken from 19 numbers of isolate sources. The pathogenic fungi were Beauveria sp., Penicillium brevicompactum, P. rubrum, Paecilomyces fulvus, Fusarium verticolloides, Pythium sp., and Aspergillus sp. Key words: Jamur entomopatogen, Coptotermes sp.

DESEMPENHO AGRONÔMICO E QUALIDADE SANITÁRIA DE GRÃOS DE MILHO, EM FUNÇÃO DA APLICAÇÃO FOLIAR DE FUNGICIDAS

2018 ◽  
Vol 20 (2) ◽  
pp. 74-90
Author(s):  
José Roberto Chaves Neto ◽  
Renato Carnellosso Guerra ◽  
Ricardo Boscaini ◽  
Nívea Raquel Ledur ◽  
Maurivan Travessini ◽  
...  
Keyword(s):  
Rio Grande ◽  
Rio Grande Do Sul ◽  
Penicillium Sp ◽  
Fusarium Sp ◽  
Aspergillus Sp

O controle das podridões das espigas e grãos de milho é realizado principalmente com a aplicação de fungicidas químicos em todas as regiões produtoras do Rio Grande do Sul. O presente trabalho teve como objetivo avaliar a influência da aplicação foliar de fungicidas na incidência de grãos ardidos e de fungos dos gêneros Penicillium sp., Fusarium sp. e Aspergillus sp. em grãos de milho. O experimento foi conduzido na safra agrícola 2014/15, em Cruz Alta, RS. O delineamento experimental utilizado foi o de blocos casualizados (DBC), com 4 tratamentos (3 com aplicação de fungicidas e 1 testemunha sem aplicação) em 4 repetições. Os tratamentos basearam-se nas aplicações dos fungicidas Piraclostrobina + epoxiconazol (380 mL ha-1), Picoxistrobina + ciproconazole (300 mL ha-1) e Azoxistrobina + benzovindiflupir (150 g ha-1). As variáveis analisadas foram: percentagem de grãos ardidos, massa de mil grãos e rendimento de grãos. Houve efeito da aplicação de fungicidas sobre toas as variáveis avaliadas. Os componentes de produção assim como a incidência de grãos ardidos e de fungos fitopatogênicos, em grãos de milho são influenciados pela aplicação via foliar de fungicidas no estádio fenológico V8 da cultura do milho.

Removal of Mn(II) and Fe(II) by Aspergillus Sp. TU-GM14 immobilized on Detarium Microcarpum matrix

2014 ◽  
Vol 16 (4) ◽  
pp. 597-608 ◽  
Keyword(s):  
Sorption Process ◽  
Isotherm Models ◽  
Freundlich Model ◽  
Equilibrium Time ◽  
Bead Size ◽  
Detarium Microcarpum ◽  
Bet Isotherm ◽  
Immobilization Matrix ◽  
Aspergillus Sp ◽  
Spore Load

<div> <p>Removal of Fe(II) and Mn(II) ions from aqueous solution by fungal biosorbent <em>Aspergillus sp. TU-GM14</em>immobilized on <em>Detarium microcarpum</em> matrix was investigated in this study. Effects of biosorption parameters pH, biosorbent concentration, bead size and equilibrium time on Fe(II) and Mn(II) ions sorption were also determined. Equilibrium was attained within in 3 hours while optimum Fe(II) and Mn(II) ions removal was observed at pH 6, 8 mm bead size, 2 g l<sup>-1</sup> spore load respectively. Adsorption capacity was described using Langmuir, Freundlich and BET isotherm models. The experimental data fitted best to the Freundlich model (<em>R</em><sup>2</sup> 0.992 and 0.996 for Mn(II) and Fe(II) respectively). Favourable surface sorption process was described by Langmuir isotherm for both metals (<em>Q</em><sub>max </sub>34 and 14 mg g<sup>-1</sup> for Mn(II) and Fe(II) ions) while the BET isotherm constant, <em>B</em>, described high metals sorption beyond the biosorbent surface in a multi-layer sorption process (4.8 and 9.0 for Mn(II) and Fe(II)&nbsp; respectively). Results of the study showed that <em>Aspergillus sp. TU-GM14 </em>biosorbent can remove large quantities of Fe(II) and Mn(II) ions from solution in both surface and multi-layer sorption process with <em>Detarium microcarpum</em> acting as a cheap immobilization matrix.</p> </div> <p>&nbsp;</p>

ANALISIS JAMUR KONTAMINAN PADA ROTI TAWAR YANG DIJUAL DI PASAR TRADISIONAL

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Nur Afni Sulastina
Keyword(s):  
Purposive Sampling ◽  
Aspergillus Sp

Latar belakang: Pangan merupakan kebutuhan dasar yang paling esensial bagi kelangsungan hidup manusia, salah satunya adalah roti tawar yang sering digunakan sebagai menu sarapan pagi sebagian masyarakat Indonesia. Roti tawar bisa dikonsumsi biasanya tidak dapat tahan lebih dari 7 hari, bahkan ada yang hanya 3 hari. Kontaminasi jamur pada makanan dapat menyebabkan kerusakan, terutama pada saat penyimpanan yang salah satunya Aspergillus sp merupakan spesies yang telah menyebar luas, karena spora jamur yang mudah disebarkan oleh angin, mudah tumbuh pada bahan-bahan pangan. Adanya mikroorganisme yang tumbuh di suatu bahan pangan sangat berpengaruh terhadap penurunan kualitas produknya. Tujuan: Diketahuinya keberadaan jamur Aspergillus sp pada roti tawar yang dijual di Pasar Tradisional. Metode: Penelitian yang digunakan adalah deskriptif, dan sampel berjumlah 16 roti tawar di pasar tradisional dengan teknik samplingnya menggunakan purposive sampling. Waktu penelitian pada bulan Maret-Juni 2018, Metode pemeriksaan dengan cara isolasi jamur Aspergillus sp dengan media Sabaroud Dextrose Agar (+). Hasil: Dari 16 sampel yang diteliti, didapatkan 1 sampel (6,2%) roti tawar yang positif ditemukan jamur Aspergillus sp dan 15 sampel (93,8%) yang negatif. Saran: Diharapkan masyarakat akat sebagai konsumen sebelum membeli roti tawar agar lebih teliti serta memperhatikan kualitas dan kebersihan roti tawar yang akan dikonsumsi serta prosuden roti agar menambah waktu kadaluwarsa pada produk rotinya. Kata kunci : Aspergillus sp, Roti Tawar, Isolasi Jamur

Distribution of representatives "malicious synergies" polyphages of the genus Fusarium spp. schlecht and aspergillus sp. nees in corn crops in Kuban

2019 ◽  
Vol 1 (76) ◽  
pp. 155-157
Author(s):  
Viktor Sokirko ◽  
◽  
Marta Nemchenko ◽  
Roman Nevzorov ◽  
Nikolay Leonov ◽  
...  
Keyword(s):  
Fusarium Spp ◽  
Genus Fusarium ◽  
Aspergillus Sp

Acyclic Isoprenoids of Endophytic Aspergillus sp. Y-12 from Panax notoginseng

2017 ◽  
Vol 14 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Qi-Ling Li ◽  
Xue-Qiong Yang ◽  
Ya-Bin Yang ◽  
Li-Xing Zhao ◽  
Guang-Yi Chen ◽  
...  
Keyword(s):  
Panax Notoginseng ◽  
Aspergillus Sp

Biotransformation of Coumarins by Filamentous Fungi: An Alternative Way for Achievement of Bioactive Analogs

2019 ◽  
Vol 16 (6) ◽  
pp. 568-577 ◽  
Author(s):  
Jainara Santos do Nascimento ◽  
João Carlos Silva Conceição ◽  
Eliane de Oliveira Silva
Keyword(s):  
Filamentous Fungi ◽  
Chemical Reactions ◽  
Biological Activities ◽  
Chemical Transformations ◽  
Chemical Structures ◽  
Pattern Structures ◽  
Pharmacological Interest ◽  
Aspergillus Sp ◽  
The Impact ◽  
Related Compounds

Coumarins are natural 1,2-benzopyrones, present in remarkable amounts as secondary metabolites in edible and medicinal plants. The low yield in the coumarins isolation from natural sources, along with the difficulties faced by the total synthesis, make them attractive for biotechnological studies. The current literature contains several reports on the biotransformation of coumarins by fungi, which can generate chemical analogs with high selectivity, using mild and eco-friendly conditions. Prompted by the enormous pharmacological interest in the coumarin-related compounds, their alimentary and chemical applications, this review covers the biotransformation of coumarins by filamentous fungi. The chemical structures of the analogs were presented and compared with those from the pattern structures. The main chemical reactions catalyzed the insertion of functional groups, and the impact on the biological activities caused by the chemical transformations were discussed. Several chemical reactions can be catalyzed by filamentous fungi in the coumarin scores, mainly lactone ring opening, C3-C4 reduction and hydroxylation. Chunninghamella sp. and Aspergillus sp. are the most common fungi used in these transformations. Concerning the substrates, the biotransformation of pyranocoumarins is a rarer process. Sometimes, the bioactivities were improved by the chemical modifications and coincidences with the mammalian metabolism were pointed out.

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