Effect of supplementing Moringa oleifera leaf extract and clove bud oil to the diet on microflora population and intestinal morphology of broiler birds

The development of a sensitive alpha-NaYF4:Yb3+, Er3+ solid-phase upconverting platform (UCP) has been realized using Moringa oleifera leaf extract for selective detection of arsenic (As III) contamination in drinking water. The presence of polyphenols in the leaves extract is shown to induce luminescence resonance transfer (LRET), diminishing thereby the Er3+ upconverting red and green emissions activated by 980 nm excitation. However, addition of As3+ species interrupts the LRET process and restores emission proportionately. This feature allows platform to selectively detect arsenic pollution in water below the safe limit of 10 ppt. The uniqueness of UCP lies in monitoring the As3+ contamination in samples containing heavy ions (Cd2+, Hg2+) as well, without apparent effect on the signal reproducibility. UCP is also found to be insensitive to other interfering ions like Pb2+, H2PO4-, F-, Cl-, Ca2+, Mg2+, Sn2+, Cr6+, Fe2+ and Co2+, if present.<br><br>

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Improving Salt Tolerance of Helianthus annuus (L.) Plants by Moringa oleifera Leaf extract

Egyptian Journal of Agronomy ◽

10.21608/agro.2016.301 ◽

2016 ◽

Vol 38 (1) ◽

pp. 117-140 ◽

Cited By ~ 4

Keyword(s):

Salt Tolerance ◽

Helianthus Annuus ◽

Leaf Extract ◽

Moringa Oleifera ◽

Helianthus Annuus L

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Bis (Isothiocyanatomethyl) Benzene, A Plant Derived Anti-Neoplastic Compound: Purified from Moringa Oleifera Leaf Extract

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520619666190206164137 ◽

2019 ◽

Vol 19 (5) ◽

pp. 677-686 ◽

Cited By ~ 2

Author(s):

Samrat Paul ◽

Piyali Basak ◽

Namrata Maity ◽

Chayan Guha ◽

Nandan Kumar Jana

Keyword(s):

Anticancer Activity ◽

Leaf Extract ◽

Moringa Oleifera ◽

Folk Medicine ◽

Drug Formulation ◽

Indigenous Species ◽

Cancer Cell Growth ◽

Apoptotic Pathway ◽

Dimeric Form ◽

Mcf 7

Background: Moringa oleifera lam, commonly known as “Sajina”, is an indigenous species to India. In our folk medicine, it is used for the treatment of Canker (cancer). The Moringa oleifera leaf extract contains many phyto-compounds, with some being anti-neoplastic in nature. Objective: Our preliminary study showed that the leaf extract significantly kills cancer cells compared to normal cells. On searching for the new phyto-compound, Bis-isothiocyanatomethyl) benzene was purified and isolated. Methods: The sequential process of fractional distillation, column chromatography, followed by TLC and HPLC is performed for purification. Every fraction from each step was tested on HeLa cell line for evaluating the presence of the phyto-compound. Results and Conclusion: FTIR peak analysis of a single phyto-compound shows the presence of thiocyanate group, aromatic carbon group. 1H & 13C NMR peak analysis along with High-resolution mass spectroscopy (HRMS) calculation confirm the chemical structure with IUPAC name [Bis (Isothiocyanatomethyl) benzene]. Previously, Isothiocyanatomethyl- benzene solely or in conjugation with sugar molecule has been reported, but its dimeric form in nature hasnot yet been published anywhere. It shows anticancer activity by retarding cancer cell growth & inhibits carcinogenesis on HeLa, MCF-7, and MDA-MB-231 cell lines by caspase 3 apoptotic pathway and showed comparatively less cytotoxicity to PBMC cell. It shows anticancer activity almost the same as the market available drug Cis-Platin. Therefore, further extrapolating its activity with different concentrations may result in its use as a drug formulation for the treatment of cancer.

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