INCIDENCE AND CAUSES OF NEONATAL JAUNDICE IN A POPULATION OF NORTH EAST INDIA

2021 ◽  
pp. 4-5
Author(s):  
Murchana Khound ◽  
Sekharjyoti Sharma

Background: Neonatal jaundice is a common cause of mortality and morbidity in newborn babies and account for up to 60% cases in term and 80% in preterm babies. Studies from different geographical areas should be done to know the causes of hyperbirubinemia properly so that a collective effort can be made to decrease the burden mortality and morbidity associated with it Objectives:To study the incidence and causes of neonatal jaundice in babies admitted in the hospital Methods: It was a hospital based observational study conducted in one of the busiest hospitals of Jorhat over a period of 12 months. Incidence and causes of neonatal jaundice in the babies born in the hospital during the study period were studied. Results: 710 newborns delivered during the study period out of which 439 (61.8%) newborns developed clinical jaundice. 290 (66%) newborns had physiological jaundice and the rest 149 (34%) developed pathological jaundice. Among the 149 babies developing pathological jaundice 87(58.3%) were males and 62(41.6%) were females. Most common cause was ABO incompability(31%) of cases, second was breast feeding jaundice (28%) , third was prematurity (12%) .Other causes were cephalohematoma(1.3%), Rh incompatibility(3.3%) , G6PD deciency(8%), sepsis(4.7%) and in 11.4% babies no denite cause was found. Conclusion: Adequate feeding, preventing premature deliveries, good monitoring of babies with ABO incompability, prematurity, Rh incompability, G6PD deciency can decrease the mortality and morbidity associated with neonatal jaundice.

2020 ◽  
Vol 8 (1) ◽  
pp. 21-23
Author(s):  
Davis Manuel ◽  
Shajahan R A

Background: In the first week of child birth, neonatal jaundice is the most common problem which leads to delayed hospital discharge and re-admissions. Recognising early neonatal hyperbilirubenemia plays a pivotal role in preventing serious complications. The aim of this study was to study the clinical profile and the aetiological factors leading to neonatal jaundice in rural areas.Subject and Method:This study is a prospective observational study  conducted in neonatal intensive care unit (NICU) and post natal ward . This study was conducted during the period of February 2017 to July 2017. Total 400 neonates were admitted in NICU and post natal ward during this period. Out of them, 100 newborns were having jaundice (Serum bilirubin > 10 mg/dl). 100 cases in total were enrolled in the study. Result:In this study,out of 100 neonates, 70% were males and 30% were females. , 92 were born at term (92%) and remaining 10 were preterm babies (10%). Physiological jaundice constituted 45%, followed by ABO incompatibility constituted 25%, followed by sepsis(1%), Rh incompatibility (8%), idioapathy (8%), prematurity (5%), cephalhematoma (4%), breast feeding (2%), haemolytic anemia (2%) were diagnosed as hereditary spherocytosis. Conclusion:Physiological jaundice is the most common cause of neonatal jaundice followed by ABO incompatibility, sepsis, Rh incompatibility and idiopathic cases. Cephalhematoma, breast feeding jaundice and haemolytic anaemia are the less common causes. Hence, it is required to monitor neonates more appropriately and accurately.


2020 ◽  
Vol 11 (3) ◽  
Author(s):  
Soheila Siroosbakht ◽  
Ali Reza Aminian ◽  
Bijan Rezakhaniha

Background: Neonatal jaundice is one of the most common neonatal problems. About 60% of term and 80% of preterm neonates have jaundice. Objectives: Due to the high prevalence of early neonatal jaundice, which can lead to mothers’ concerns and even hospitalization of neonates, we decided to study the frequency and risk factors of breast feeding jaundice to determine the role of gynecologists and nurses in the development of this type of jaundice. Methods: This study was a cross-sectional descriptive study. The sampling method was by convenience. Study populations included one hundred terms, exclusively breastfed neonates aged equal or less than seven days with jaundice who were admitted in Golestan and Khanevadeh hospitals Tehran, Iran from July 2019 to January 2020. Results: The percentage of causes of jaundice in the study population was 65% non-breastfeeding jaundice (29 male, 36 female), including 36% blood group incompatibility, 19% Rh incompatibility and 10% G6PD deficiency. The amount of breast feeding jaundice was 35% (18 male, 17 female). The most significant factors in breastfeeding jaundice were: use of water or sugar water, depressed nipple, mother’s unwillingness to breastfeed; inappropriate breastfeeding technique, and birth weight < 2500 g. Conclusions: The high prevalence of breastfeeding jaundice indicates that policies of breastfeeding education need to be revised. Breastfeeding education before delivery, attention of gynecologists to breast problems of mothers during pregnancy, professional coordination of nurses and physicians for effective breastfeeding training, and early mothers’ revisit after the initial discharge of neonates can reduce the frequency of breastfeeding jaundice and readmission of neonates.


2017 ◽  
Vol 08 (S 01) ◽  
pp. S37-S43
Author(s):  
Binoy Kumar Singh ◽  
Abinash Dutta ◽  
Shameem Ahmed ◽  
Zakir Hussain ◽  
Rajib Hazarika ◽  
...  

ABSTRACTBackground: Traumatic brain fungus is manifestation of neglected head injury. Although rare it is not uncommon. The patients are usually intact with good Glasgow coma (GCS) score inspite of complex injuries and exposed brain parenchyma but morbidity and mortality is very high with time if no proper and timely management is offered. There is very less study on traumatic brain fungus with no defined management protocols. So an attempt was made to explain in details the surgical strategies and other management techniques in patients with traumatic brain fungus. Aims: To study and evaluate the pattern of causation, clinical presentations, modalities of management of traumatic brain fungus and outcome after treatment. Methods: All patients with fungus cerebri, admitted to our centre from January 2012 to December 2015 were studied prospectively. All the patients were examined clinically and triaged urgently for surgery. CT head was done in all patients to look for any brain parenchymal injury. All patients were managed surgically. Outcome was assessed as per the Glassgow Outcome Score. Results: Total 10 patients were included in the study. 8 were men and 2 women. The patients' ages ranged from 3-48 years (mean 31.6 years). The interval between initial injury and protrusion ranged from 3 days to 6 days (mean 4.1 days). Mean GCS at the time of presentation was 13.2.60% of the patients (n =6) sustained moderate head injury. (GCS-9-13). Size of the fungus ranged from 5cm×3cm to 8cm×10cm. Conclusion: Early and proper local wound treatment prevents fungus formation. Pre-emptive antibiotics, AEDs and cerebral decongestants are recommended. Loose water-tight duroplasty prevents CSF leak. But mortality and morbidity can be reduced significantly if brain fungus is managed properly by applying basic surgical principles and antibiotic protocols combined with newer surgical modalities.


2019 ◽  
Vol 6 (5) ◽  
pp. 2077
Author(s):  
Keerthana T. N. Gubbari

Background: Acute diarrheal disease is one of the most common cause of mortality and morbidity in under 5 children. Rotavirus is one of the important cause of diarrhea in under 5. This study was done to know the electrolyte disturbance in under 5 children with diarrhea.Methods: A prospective observational study was conducted in Masonic Medical Centre for Children, Coimbatore on children aged less than 5 years with acute diarrhea with moderate and severe dehydration.Results: Total 220 children are included in study, among them 66(58.9%) had rotavirus infection. Among 220 cases of diarrhea 14.09% (31/220) had hypernatremia, 2.72% (6/220) had hyponatremia, 4.54% (10/220) had hyperkalemia and 9.09% (20/220) had hypokalemia. Among 66 cases of rotavirus diarrhea, 27.27% (18/66) had hypernatremia, 4.5% (3/66) had hyponatremia and 25.75% (17/66) had hypokalemia.Conclusions: Hypernatremia is the most common electrolyte disturbance in acute diarrheal diseases and most frequently seen in rotavirus diarrhea. In most of the situation, there is unavailability of laboratory or time lag in obtaining reports. Hence prediction of electrolyte disturbance and management is more important in diarrheal disease.


2018 ◽  
Vol 5 (6) ◽  
pp. 2188
Author(s):  
Sandeep Garg ◽  
Samrat Mehta ◽  
Ajay Sankhe ◽  
Soumya Alukuchi

Background: Neonatal jaundice is the most common cause of readmission after discharge from birth hospitalization. Breastfeeding failure jaundice (BFFJ) is an important subtype of pathological neonatal jaundice. It typically occurs with lactation failure during the first postnatal week that leads to insufficient intake, dehydration, weight loss and sometimes hypernatremia. Incidence of breast-feeding failure is expected to rise as the exclusive breast-feeding rates are rising. This problem is not well studied especially in Indian setting hence study was conducted.Methods: This was retrospective observational study done in Department of Pediatrics from the April 1, 2016 to March 31, 2018. 179 neonates, who presented with jaundice as main complaint with total bilirubin value above the age & risk factor matched cut off, were sampled and their clinical data was analyzed.Results: Breast feeding failure jaundice contributed 31.8% (N = 57) cases, second to the exaggerated physiological hyperbilirubinemia (48% N = 86), followed by hemolytic (13.8%, N = 25). BFFJ presented at median age of 6.8 days and had mean duration of hospital stay of 3 days. Incidences of exaggerated physiological jaundice and BFFJ were found to be higher in winter months i.e. 6.7% (N = 48/716) compared to summer months i.e. 4.1% (N = 28/679) significantly (p value = 0.045).Conclusions: Breast feeding failure jaundice (BFFJ) contributed to one third of cases of neonatal pathological jaundice requiring re-admission and is the second most common cause after exaggerated physiological jaundice. The high incidence of BFFJ in the study warrants focused efforts for a structured program of breast-feeding education, training and surveillance.


Author(s):  
V. Premsai ◽  
G. Ramya ◽  
Y. Kavya Chowdary ◽  
Syeda Zaineb Humaira Hussaini ◽  
C. Aparna

Background: Neonatal jaundice is generally harmless, but high concentrations of unconjugated bilirubin may rarely cause kernicterus. Hyperbilirubinemia is the most common cause of neonatal readmission to the hospital, in the majority of cases. Aims: The study aims to determine incidence rate of neonatal jaundice as well as evaluate the commonest cause and determine the efficacy of continuous phototherapy. Study Design: A Prospective observational study. Place and Duration of Study: The study was conducted in Avis Ankura hospital for women and children. It is a well-recognized, authorized hospital where obstetrics and neonatal care is provided. The study was conducted between October 2018 to March 2019. Methodology: The study was conducted in Avis Ankura hospital for women and children. It is a well-recognized, authorized hospital where obstetrics and neonatal care is provided. A total of 162 neonates were considered. Informed consent was obtained from all the subject’s care takers. Subjects enrolled in the study were admitted in NICUs’. This study appraises the conventional cause of NNJ, evaluates the efficacy of continuous phototherapy and detects the phototherapy induced adverse reactions by using Naranjo’s causality assessment scale. Results: Among 162 patients, 94 patients (58%) were found to be males and 68 patients (42%) were found to be females. Low birth weight neonates (43.20%) were found to be more prone to neonatal jaundices. In this study, it was found that duration of phototherapy was longer in extremely low birth weight neonates (34 hours) in relation to birth weight and average duration of phototherapy. Based on the conventional cause, physiological cause (56.79%) was observed to be highest among other causes of neonatal jaundice. The short term adverse reactions due to phototherapy were identified using Naranjo’s Causality Assessment Scale. The TSB levels were increased before phototherapy (pre- treatment) and decreased after phototherapies (post-treatment) which were assessed by using American Academy of Pediatrics guidelines. Conclusion: From this study, it was concluded that males were more prone to develop neonatal jaundice when compared with females. Physiological jaundice contributes majority of cases   among the total cases. The use of phototherapy was inversely related to gestational age and birth weight.


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