scholarly journals Neonates with Jaundice A Clinical Profile

2020 ◽  
Vol 8 (1) ◽  
pp. 21-23
Author(s):  
Davis Manuel ◽  
Shajahan R A
Keyword(s):  
Breast Feeding ◽  
Neonatal Intensive Care ◽  
Neonatal Jaundice ◽  
Prospective Observational Study ◽  
Clinical Profile ◽  
Abo Incompatibility ◽  
Common Causes ◽  
Rh Incompatibility ◽  
Preterm Babies ◽  
Haemolytic Anemia

Background: In the first week of child birth, neonatal jaundice is the most common problem which leads to delayed hospital discharge and re-admissions. Recognising early neonatal hyperbilirubenemia plays a pivotal role in preventing serious complications. The aim of this study was to study the clinical profile and the aetiological factors leading to neonatal jaundice in rural areas.Subject and Method:This study is a prospective observational study  conducted in neonatal intensive care unit (NICU) and post natal ward . This study was conducted during the period of February 2017 to July 2017. Total 400 neonates were admitted in NICU and post natal ward during this period. Out of them, 100 newborns were having jaundice (Serum bilirubin > 10 mg/dl). 100 cases in total were enrolled in the study. Result:In this study,out of 100 neonates, 70% were males and 30% were females. , 92 were born at term (92%) and remaining 10 were preterm babies (10%). Physiological jaundice constituted 45%, followed by ABO incompatibility constituted 25%, followed by sepsis(1%), Rh incompatibility (8%), idioapathy (8%), prematurity (5%), cephalhematoma (4%), breast feeding (2%), haemolytic anemia (2%) were diagnosed as hereditary spherocytosis. Conclusion:Physiological jaundice is the most common cause of neonatal jaundice followed by ABO incompatibility, sepsis, Rh incompatibility and idiopathic cases. Cephalhematoma, breast feeding jaundice and haemolytic anaemia are the less common causes. Hence, it is required to monitor neonates more appropriately and accurately.

scholarly journals Clinical profile and aetiological factors of neonatal jaundice from a rural area of Kutch, Gujarat, India

2020 ◽  
Vol 8 (1) ◽  
pp. 143
Author(s):  
Avinash Patel ◽  
Karan Saradava ◽  
Hasmukh Chauhan
Keyword(s):  
Birth Weight ◽  
Neonatal Intensive Care ◽  
Neonatal Jaundice ◽  
Prospective Observational Study ◽  
Medical Science ◽  
Clinical Profile ◽  
Rural Setting ◽  
Abo Incompatibility ◽  
Rh Incompatibility ◽  
Blood Grouping

Background: Etiology of hyperbilirubinemia is not only crucial for optimal management of the patient but also it may have implications for subsequent pregnancies. The objective of this study was to study the clinical profile and the underlying aetiological factors leading to neonatal jaundice in this rural setting of Kutch District, Gujarat, India.Methods: This prospective observational study was conducted in the neonatal intensive care unit (NICU) and Post Natal ward Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat. Total of 150 cases were enrolled for the study. Blood grouping and Rh typing of baby and mother were done. Cord blood bilirubin and haemoglobin, direct coomb's test (DCT) and bilirubin monitoring were done whenever there was a setting for Rh incompatibility.Results: Among 150 neonates studied, majority had birth weight between 2501g and 3000g. Only 21 babies had birth weight <2.5kg (14%) (Table 2). Of the 150 neonates 85 were males and 65 were females.Conclusions: This study concludes that physiological jaundice is the most common cause of neonatal jaundice in our hospital. This is followed by ABO incompatibility, sepsis, Rh incompatibility and idiopathic cases.

INCIDENCE AND CAUSES OF NEONATAL JAUNDICE IN A POPULATION OF NORTH EAST INDIA

2021 ◽  
pp. 4-5
Author(s):  
Murchana Khound ◽  
Sekharjyoti Sharma
Keyword(s):  
Observational Study ◽  
Breast Feeding ◽  
Neonatal Jaundice ◽  
Common Cause ◽  
Mortality And Morbidity ◽  
North East India ◽  
North East ◽  
Collective Effort ◽  
Rh Incompatibility ◽  
Preterm Babies

Background: Neonatal jaundice is a common cause of mortality and morbidity in newborn babies and account for up to 60% cases in term and 80% in preterm babies. Studies from different geographical areas should be done to know the causes of hyperbirubinemia properly so that a collective effort can be made to decrease the burden mortality and morbidity associated with it Objectives:To study the incidence and causes of neonatal jaundice in babies admitted in the hospital Methods: It was a hospital based observational study conducted in one of the busiest hospitals of Jorhat over a period of 12 months. Incidence and causes of neonatal jaundice in the babies born in the hospital during the study period were studied. Results: 710 newborns delivered during the study period out of which 439 (61.8%) newborns developed clinical jaundice. 290 (66%) newborns had physiological jaundice and the rest 149 (34%) developed pathological jaundice. Among the 149 babies developing pathological jaundice 87(58.3%) were males and 62(41.6%) were females. Most common cause was ABO incompability(31%) of cases, second was breast feeding jaundice (28%) , third was prematurity (12%) .Other causes were cephalohematoma(1.3%), Rh incompatibility(3.3%) , G6PD deciency(8%), sepsis(4.7%) and in 11.4% babies no denite cause was found. Conclusion: Adequate feeding, preventing premature deliveries, good monitoring of babies with ABO incompability, prematurity, Rh incompability, G6PD deciency can decrease the mortality and morbidity associated with neonatal jaundice.

scholarly journals Exchange Transfusion: Indication and Adverse Effect

2012 ◽  
Vol 36 (1) ◽  
pp. 16-19 ◽  
Author(s):  
Suraiya Begum ◽  
Md Abdul Baki ◽  
Gopen Kundu ◽  
Imnul Islam ◽  
Manik Kumar Talukdar ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Adverse Events ◽  
Medical Records ◽  
Exchange Transfusion ◽  
Neonatal Jaundice ◽  
Common Complication ◽  
Abo Incompatibility ◽  
Special Care Baby Unit ◽  
Common Causes ◽  
Rh Incompatibility

Objective: To determine the indication and complications of exchange transfusion (ET) performed for neonatal hyperbilirubinaemia. Methods: The medical records of infants < 28 days old who required exchange transfusion (ET) due to neonatal jaundice in Special Care Baby Unit (SCABU), BIRDEM hospital from January 2009 to April 2010 were retrospectively reviewed. Results: Exchange transfusion was performed in 30 neonates during the study period. Indications of exchange transfusion were ABO incompatibility (30.0%), Rh incompatibility (13.3%), septicaemia (6.6%) and in majority causes, were unidentified (50%). Most common complication were thrombocytopenia (33.3%) hyperkalaemia (20%), hypocalcaemia (16.7%) Conclusion: Indication of ET was unidentified in majority cases and among identified cases most common causes was ABO incompatibility. Adverse events were common after exchange transfusion.DOI: http://dx.doi.org/10.3329/bjch.v36i1.13029Bangladesh J Child Health 2012; Vol 36 (1): 16-19

scholarly journals Prospective study of clinical profile, causes, risk factors and treatment of hyperbilirubinemia in preterm and term babies

2018 ◽  
Vol 5 (5) ◽  
pp. 1851
Author(s):  
Komal Garg ◽  
Vamshi Krishna Kondle
Keyword(s):  
Risk Factors ◽  
Common Factors ◽  
Developing Nations ◽  
Clinical Profile ◽  
Neurological Injury ◽  
Pediatric Hospital ◽  
Mortality And Morbidity ◽  
Abo Incompatibility ◽  
Rh Incompatibility ◽  
Preterm Babies

Background: Neonatal jaundice is often physiologic and benign, but dangerous, at levels producing neurological injury, adding on to mortality and morbidity in developing nations. Hence the present study is undertaken to document the proportion, clinical profile, causes, risk factors and treatment of hyperbilirubinemia in preterm and term babies.Methods: This study conducted over 100 hyperbilirubinemia babies who admitted in Rich Pediatric Hospital, Pogathota, Nellore during the period of October 2014 to September 2015.Hyperbilirubinemia is more common among preterm babies born to mothers of 19-22 years and term babies born to mothers of 21-26 years age group.Results: The most common etiological factors identified among all the gestational categories were sepsis (23.0%) followed by ABO incompatibility (20.0%) and Rh incompatibility (6.0%). Among preterm babies (35-37 wks.) the most common were ABO incompatibility (15.0%), Sepsis (10.0%) and polycythemia (10.0%), while among term babies, the most common factors were ABO incompatibility (23.9%), Sepsis (16.4%) Rh incompatibility (7.5%) and Cephalhaematoma (7.5%). In a large proportion of cases, etioliogy remined idiopathic (44.0%).Conclusions: Requirement of exchange transfusion was more among term babies compared to preterm babies. Rh incompatibility was the only etiology.

scholarly journals Clinical profile of pathological Jaundice among neonates admitted in the National Referral Hospital, Bhutan

2021 ◽  
Vol 7 (2) ◽  
pp. 13-18
Author(s):  
Kinzang Dechen ◽  
Tenzin Lhadon ◽  
Mimi Lhamu Mynak ◽  
Phurpa Phurpa
Keyword(s):  
Weight Loss ◽  
Neonatal Intensive Care ◽  
Neonatal Jaundice ◽  
Referral Hospital ◽  
Clinical Profile ◽  
Excessive Weight Loss ◽  
Cross Sectional ◽  
Abo Incompatibility ◽  
Excessive Weight ◽  
National Referral Hospital

Background: Neonatal jaundice is a common condition especially in the first week of life. There are various maternal and neonatal clinical characteristics that have been associated with pathological jaundice. Objectives: To describe clinical profile of pathological jaundice and to estimate its prevalence among newborns admitted at the National Referral Hospital. Methods: A cross-sectional descriptive study design was used to study pathological jaundice cases admitted at the Gyaltsuen Jetsun Pema Neonatal Intensive Care Unit (NICU) of Jigme Dorji Wangchuck National Referral Hospital (JDWNRH) from 7th November 2018 till 6th November 2019. Data was collected using a predesigned case proforma, entered and analyzed in Epidata after obtaining ethical clearance from the Research Ethics Board of Health (REBH), Bhutan.  Results: Facility based prevalence rate of pathological neonatal jaundice was found to be 63.66% in our setting. The median age on presentation was 4 days. Blood group ABO incompatibility and neonates less than one week of age were found to be most common neonatal profile in this study. Significant association was found between primiparous mothers and excessive weight loss. Conclusion: The prevalence of pathological jaundice was high in our setting. ABO incompatibility, neonates less than one week of age, primigravida mothers with feeding issues should be closely followed or screened for pathological jaundice especially during the first one week of life. Keywords: Pathological jaundice, Prevalence, ABO incompatibility, feeding issues, excessive weight loss

scholarly journals Etiological study of jaundice in neonates

2019 ◽  
Vol 6 (5) ◽  
pp. 1881
Author(s):  
Jasraj Bohra ◽  
Chuba Kumzuk L. C. R.
Keyword(s):  
Neonatal Intensive Care ◽  
Abnormal Finding ◽  
Medical College ◽  
Abo Incompatibility ◽  
Circulatory Insufficiency ◽  
Rh Incompatibility ◽  
Etiological Study ◽  
Motor Retardation ◽  
Preterm Babies ◽  
Intrauterine Infections

: Jaundice is the commonest abnormal finding with an incidence of about 60% in term babies and 80% in preterm babies. It is the commonest cause of admission to hospitals in the newborn period. In preterm babies, the percentage is exceedingly high due to their physiological handicaps and other hazards of prematurity like Asphyxia, septicemia, respiratory and circulatory Insufficiency. Non-physiological or pathological jaundice is also known to occur in (8-9)% of newborns. Its timely detection and optimal management are crucial to prevent brain damage and subsequent neuro-motor retardation. Aims of this study to find out the etiology of jaundice in neonates, admitted in neonates unit attached to SMS medical college Jaipur.Method: This Observational study was conducted in Neonatal Intensive Care Unit (NICU) and Post Natal Ward attached to SMS medical college Jaipur, after approval from the hospital ethical committee, over a period of 12 months(October 2011 to September 2012. Study was carried on 500 neonates presenting clinically with neonatal hyperbilirubinemia.Result: The onset of jaundice was seen maximum between live hour 24-72 hours (n=290, 58% cases), followed by live hour 72 hours-14 days (n=160, 32%). At more than 2 weeks there was only 3 case (0.6%). The etiological factors in the causation of jaundice in the decreasing order of frequency were exaggerated physiological jaundice accounts for (28%), ABO-incompatibility (24.4%), Rh-incompatibility (13.8%), Idiopathic (10.4%), cephalhematoma (10.2%), septicemia (6%), intrauterine infections (4%), BMJ (1.8%), Galactocemia (0.8%) and G6PD  Deficiency (0.6%) respectively.Conclusion: Hyperbilirubinemia is more severe in newborns, therefore precautionary measure should be adopted by both parents, and clinicians to diagnose and treat the diseases properly.

scholarly journals Clinical Profile and Outcome of Neonates Admitted to Neonatal Intensive Care Unit of NGMC

2017 ◽  
Vol 15 (1) ◽  
pp. 20-22
Author(s):  
Roma KM ◽  
Manita Pyakurel ◽  
Veena Gupta ◽  
Piush Kanodia
Keyword(s):  
Neonatal Sepsis ◽  
Neonatal Intensive Care ◽  
Neonatal Period ◽  
Study Data ◽  
Clinical Profile ◽  
Mortality And Morbidity ◽  
Medical Practitioners ◽  
Common Causes ◽  
Causes Of Mortality ◽  
The Common

Background: Neonatal period is a period from birth to under 28 days of life. The common causes of mortality and morbidity in our region are preventable, among which neonatal sepsis is the commonest one. Most of the deaths occur within 7 days of life. Objectives: To study the clinical profile, pattern of diseases, causes of morbidity and mortality amongst newborns. Materials and methods: A hospital based descriptive study was done among total 967 newborns including both inborn and out born admitted in NICU, NGMC from January 2016 to December 2016. Age, sex, gestational age, diagnosis at admission, outcome of admitted th newborns were the main variables under study. Data was entered in Excel and analyzed using SPSS 20th version. Data were presented through pie, bar graph and table with frequency and percentage. Results: Male were predominant in the study (65%). One third of the admitted newborns were preterms. Half of the admitted newborns were admitted on their first day of life. Neonatal sepsis was the most common cause of admission. Deaths occured in 7.4%of total babies. Seventy-six percent got improved after treatment. Only 2.8% were referred to higher center. Conclusions: Most of the neonates got admitted in first day of life with commonest cause being neonatal sepsis. Recovery rate was satisfactory. To reduce the mortality and morbidity of neonates, we need to increase awareness level in general population and proper aseptic practices in medical practitioners.

scholarly journals Risk Factors of Early Breastfeeding Jaundice: How Can Gynecologists and Nurses be Effective in Reducing It?

2020 ◽  
Vol 11 (3) ◽  
Author(s):  
Soheila Siroosbakht ◽  
Ali Reza Aminian ◽  
Bijan Rezakhaniha
Keyword(s):  
Risk Factors ◽  
Breast Feeding ◽  
Neonatal Jaundice ◽  
Preterm Neonates ◽  
Cross Sectional ◽  
Breastfeeding Education ◽  
High Prevalence ◽  
Rh Incompatibility ◽  
Study Population ◽  
Neonatal Problems

Background: Neonatal jaundice is one of the most common neonatal problems. About 60% of term and 80% of preterm neonates have jaundice. Objectives: Due to the high prevalence of early neonatal jaundice, which can lead to mothers’ concerns and even hospitalization of neonates, we decided to study the frequency and risk factors of breast feeding jaundice to determine the role of gynecologists and nurses in the development of this type of jaundice. Methods: This study was a cross-sectional descriptive study. The sampling method was by convenience. Study populations included one hundred terms, exclusively breastfed neonates aged equal or less than seven days with jaundice who were admitted in Golestan and Khanevadeh hospitals Tehran, Iran from July 2019 to January 2020. Results: The percentage of causes of jaundice in the study population was 65% non-breastfeeding jaundice (29 male, 36 female), including 36% blood group incompatibility, 19% Rh incompatibility and 10% G6PD deficiency. The amount of breast feeding jaundice was 35% (18 male, 17 female). The most significant factors in breastfeeding jaundice were: use of water or sugar water, depressed nipple, mother’s unwillingness to breastfeed; inappropriate breastfeeding technique, and birth weight < 2500 g. Conclusions: The high prevalence of breastfeeding jaundice indicates that policies of breastfeeding education need to be revised. Breastfeeding education before delivery, attention of gynecologists to breast problems of mothers during pregnancy, professional coordination of nurses and physicians for effective breastfeeding training, and early mothers’ revisit after the initial discharge of neonates can reduce the frequency of breastfeeding jaundice and readmission of neonates.

scholarly journals A study of clinical profile of neonates with respiratory distress and predictors of their survival admitted in neonatal intensive care unit of tertiary care hospital

2017 ◽  
Vol 4 (6) ◽  
pp. 2027
Author(s):  
Pushpak H. Palod ◽  
Bhagwat B. Lawate ◽  
Mahesh N. Sonar ◽  
Sneha P. Bajaj
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Respiratory Distress ◽  
Neonatal Intensive Care ◽  
Clinical Profile ◽  
Care Hospital ◽  
Corticosteroid Administration ◽  
Neonatal Septicaemia ◽  
Common Causes

Background: Respiratory disorders are the most frequent cause of admission for neonatal intensive care in both term and preterm infants. The clinical diagnosis of respiratory distress in a newborn is suspected if the respiratory rate is greater than 60 per minute in a quite resting baby, presence of grunting and/or there are inspiratory subcostal/intracostal retractions Signs and symptoms of respiratory distress include cyanosis, grunting, nasal flaring, retractions, tachypnea, decreased breath sounds with or without rales and/or rhonchi, and pallor. Objectives of present study were to know the clinical profile and aetiology of neonates with respiratory distress and to study the morbidity and mortality of respiratory distress in neonatal intensive care unit (NICU). And to find out the predictors of survival in the neonates admitted with respiratory distress.Methods: Study is done on 281 neonates admitted in Neonatal Intensive Care Unit (NICU) as a Prospective Cohort and Descriptive Study and Simple Random sampling is used to include neonates in the study. All the neonates included in study were subjected to the following detailed perinatal history and thorough clinical examination of newborns was done.Results: Males outnumber the females in admission. Most of the affected neonates were weighing between 1500g to 2500g (185). Out of total patients of two hundred and eighty-one, there were 35 deaths (12.5%) and 246 patients survived (87.5%). In present study most common causes for respiratory distress were respiratory distress syndrome (31.3%), neonatal septicaemia including pneumonia (28.1%), TTBN (16.7%).Conclusions: The overall survival rate was 87.5%. Male outnumber female on admissions but the survival in females was better than males. Common causes of respiratory distress in our study are RDS, Neonatal septicaemia and TTBN. As the gestation increased the survival also improved. Term neonates had better survival as compared to preterm neonates. Antenatal corticosteroid administration improved the survival. 

scholarly journals Study of clinical spectrum of hyperbilirubinemia with frequency of glucose six phosphate dehydrogenase deficiency in neonates

2021 ◽  
Vol 9 (6) ◽  
pp. 1674
Author(s):  
Keshawati Goel ◽  
Anshuman Srivastava
Keyword(s):  
G6pd Deficiency ◽  
Prospective Observational Study ◽  
Dehydrogenase Deficiency ◽  
Uttar Pradesh ◽  
Neurological Deficits ◽  
Medical College ◽  
Abo Incompatibility ◽  
Mucous Membranes ◽  
Rh Incompatibility ◽  
Breast Fed

Background: Jaundice is defined as visible reflexion of serum hyperbilirubinemia on mucous membranes and skin as yellowish discoloration. The frequency of icterus among neonates is about 1 in 2500-5000 live births. When there is disparity between the production of bilirubin, conversion from unconjugated to conjugated bilirubin and excretion of bilirubin results in jaundice. Unconjugated bilirubin is usually harmless but it can also cross blood-brain barrier causing neurotoxicity or kernicterus.Methods: A hospital based prospective observational study which is carried out in the department of paediatrics of Teerthanker Mahaveer Medical College, Moradabad, Uttar Pradesh from December 2019 to November 2020 on 74 neonates who required admission for hyperbilirubinemia.Results: The most common jaundice occurred in neonates were idiopathic or breastfeeding jaundice as the neonates were breast fed (47.29%). The second most common cause was ABO incompatibility leading to jaundice in 27 (36.48%) neonates. Incidence of neonatal Sepsis, G6PD deficiency, hypothyroidism and cephalhematoma was 22.9%, 4.1%, 2.70% and 4.1% respectively. Polycythemia contributed to 1.35% and the frequency of hyperbilirubinemia in infants of diabetic mother’s or GDM was 10.8%. Rh incompatibility was seen in 13.5%.Conclusions: G6PD deficiency is a significant cause for NNHB and the cases with pathological jaundice if left untreated may lead to severe neurological deficits and lifelong disabilities, hearing impairment, mental retardation, seizures and movement disorders. Hence we recommend G6PD screening in every newborn with significant hyperbilirubinemia to reduce morbidity and mortality.

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