scholarly journals STUDY OF CORRELATION BETWEEN THE CYTOLOGICAL AND HISTOPATHOLOGICAL FINDINGS OF NON-NEOPLASTIC AND NEOPLASTIC BREAST LESION

2019 ◽  
pp. 1-2
Author(s):  
Rina Kumari
Keyword(s):  
Observational Study ◽  
Invasive Ductal Carcinoma ◽  
Gold Standard ◽  
Breast Lesion ◽  
Prospective Observational Study ◽  
Ductal Carcinoma ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Neoplastic Lesion ◽  
Lesion Method

Background: Study of correlation between the cytology and histopathological ndings of nonneoplastic and neoplastic breast lesion. Method : The present prospective observational study was conducated in jlnmc for a period of 6 months from 15th April to 14th Sept. we had studied 100 cases and specimens were received in histopathological section of our department.Gross examination of speciemens did followed by xation ,proper sampling and tissue processing. Result: Total 100 cases were studied of which 38 cases were nonneoplastic, 36 cases were benign neoplastic lesion,5 cases borderline and 21 cases were malignant.Over all broadenoma was most common benign lesion with 18 cases. Invasive ductal carcinoma nos were most common malignant lesion followed by lobular carcinoma.malignant phylloid was the most common nonepithelial malignancy. Conclusion: Histology remains gold standard for diagnosis of breast lesion

scholarly journals Prognostic Significance of Fibrotic Focus in Invasive Ductal Carcinoma of the Breast: A Prospective Observational Study

2002 ◽  
Vol 15 (5) ◽  
pp. 502-516 ◽  
Author(s):  
Takahiro Hasebe ◽  
Satoshi Sasaki ◽  
Shigeru Imoto ◽  
Kiyoshi Mukai ◽  
Tomoyuki Yokose ◽  
...  
Keyword(s):  
Observational Study ◽  
Invasive Ductal Carcinoma ◽  
Prospective Observational Study ◽  
Ductal Carcinoma ◽  
Prognostic Significance ◽  
Carcinoma Of The Breast ◽  
Fibrotic Focus

scholarly journals Histopathological spectrum of neoplastic and non-neoplastic breast lesions: A three years study in rural tertiary care center.

2020 ◽  
Vol 7 (01) ◽  
pp. 4721-4725
Author(s):  
Dr. Sanjeev Kumar Singh ◽  
Dr. Geeta Maurya ◽  
Dr. Pinki Pandey ◽  
Dr. Rashmi
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Care Center ◽  
Benign Lesion ◽  
Tertiary Care ◽  
Age Distribution ◽  
Morbidity And Mortality ◽  
Histopathological Diagnosis ◽  
Breast Lesions ◽  
Neoplastic Lesions

Background: Breast tumours are very common cause of morbidity and mortality worldwide specially in developing countries. Breast lesions show broad spectrum of disease patterns in respect to benign, malignant, and non-neoplastic. Breast cancer is one of the most frequently occurring cancer among women. Objective: To study the frequency, age distribution, clinical and histological patterns of neoplastic and non-neoplastic lesions of breast in this rural population. Material and methods: This observational study was conducted over a duration of three years. In which we studied 210 cases of breast lesions. Specimens were received in department of pathology. Grossing, tissue processing, staining done according to standard protocol. Haematoxylin and eosin (H&E) stained sections were examined under microscope to categorise different type of lesions in the form of non-neoplastic and neoplastic. Results:  Out of 210 breast lesions, fibroadenoma was the commonest (114 cases) benign lesion. While invasive ductal carcinoma (70 cases) was commonest in malignant category. Non neoplastic lesions stand on third place, study showed 6 cases out of 210 total cases, in which acute mastitis (4 cases) was most common. Benign tumours were mostly seen in 2nd and 3rd decade and malignant tumour mainly in 5th and 6th decade Conclusion: Early histopathological diagnosis of breast lesions is very important to differentiate between benign and malignant lesions. Large number of cases of invasive ductal carcinoma (>33% of all cases) were seen in our study, which is a serious concern. So, generation of awareness among women is need of time to reduce the morbidity and mortality specially in Indian rural setup

scholarly journals A clinicopathological study of masses of nasal cavity paranasal sinuses and nasopharynx

2017 ◽  
Vol 3 (2) ◽  
pp. 253
Author(s):  
Rajat Sharma ◽  
Dimple Sahni ◽  
Kuljeet Uppal ◽  
Rajeev Gupta ◽  
Gifty Singla
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Histopathological Diagnosis ◽  
Radiological Findings ◽  
Female Ratio ◽  
Road Map ◽  
Neoplastic Lesion ◽  
Nasopharyngeal Masses

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">A variety of inflammatory, non neoplastic and neoplastic masses involving nasal cavity, paranasal sinuses and nasopharynx are commonly encountered in ENT clinics. The objective was to study the demographic profile, clinical presentation, radiological findings and its correlation with the histopathological findings of masses of nasal cavity, paranasal sinuses and nasopharynx. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The study was conducted on patients having sinonasal and nasopharyngeal masses admitted in dept of ENT, GMC, Patiala from August 2014 to July 2016. The study was designed to evaluate demographic distribution, clinicopathological features, radiological findings of sinonasal and nasopharyngeal masses and to evaluate the correlation of clinical and radiological findings with histopathological diagnosis.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Analysis of 50 cases of masses in nasal cavity, paranasal sinuses and nasopharynx was done. Male to female ratio was 1.38:1. The commonest site was nasal cavity followed by paranasal sinuses. Nasal polyp was the most common non-neoplastic lesion. Among the neoplastic lesions studied, inverted papilloma was the most common benign lesion and squamous cell carcinoma was the most common malignant lesion observed. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">For proper evaluation of sinonasal and nasopharyngeal masses, clinical, radiological and histopathological evaluation should be done in all patients. Although radiology provides a road map to endoscopic surgeons for any existing or impending complications but histopathology always gives a confirmatory diagnosis.</span></p>

scholarly journals MAMMOGRAM: DETECTION OF MALIGN TUMORS IN WOMEN FROM SANTA CATARINA AND BRAZIL

2016 ◽  
Vol 25 (3) ◽  
Author(s):  
Luciana Martins da Rosa ◽  
Luciana da Silva ◽  
Vera Radunz ◽  
María Angélica Arzuaga
Keyword(s):  
Breast Cancer ◽  
Information Technology ◽  
Observational Study ◽  
Breast Lesion ◽  
Incidence Rates ◽  
Santa Catarina ◽  
Unified Health System ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions ◽  
Proportional Distribution

ABSTRACT The purpose is to analyze the incidence rate of malignant neoplastic lesion by detection type and the proportional distribution of mammograms in women between 40 and 69 years of age from the State of Santa Catarina and from Brazil. This is a descriptive observational study of data from the Information Technology Department of the Unified Health System between 2009 and 2012 and the Brazilian Institute of Geography and Statistics. The greatest mammography coverage was in the group from 45 to 49 years, 22.2% in Brazilians and 23.1% in women from Santa Catarina. The greatest proportional distribution was 89.2% in Brazilian women between 40 and 44 years and women from Santa Catarina between 50 and 54 years. The incidence rates of malignant neoplastic breast lesion diagnosed by imaging increased in Brazil and Santa Catarina. In Brazil, in 2012, the highest detection was by palpation and, in Santa Catarina, by imaging. In conclusion, the screening is below the recommended, the higher proportional distributions of mammograms permitted a larger number of diagnoses of malignant neoplastic lesions and the application of mammograms as from the age of 40 years contributed to the diagnosis of breast cancer between the ages of 40 and 49 years.

scholarly journals Pattern of Fine Needle Aspiration Cytology of Superficially Palpable Lesions: One year hospital based study

1970 ◽  
Vol 9 (2) ◽  
pp. 25-29
Author(s):  
E Piya ◽  
R Panth ◽  
S Singh
Keyword(s):  
Salivary Gland ◽  
Lymph Node ◽  
Ductal Carcinoma ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Aspiration Cytology ◽  
Chronic Sialadenitis ◽  
Wide Range ◽  
Malignant Lesions ◽  
One Year

Introduction: This is a retrospective study on fine need aspiration cytology (FNCA) of superficially palpable lesions done in Shree Birendra Hospital, Chhauni, over a period of one year from 14th April 2008 to 13th April 2009. Aim: The aim of this study was to review cytological diagnosis on superficially palpable lesions in various sites. Methods: A total of 323 cytological diagnoses of palpable lumps performed in one year by pathologists were retrieved. Sites of FNA and diagnoses were analyzed and correlated with age and sex of the patients. Results:This study has included 323 FNACs. Lymph node was the most common site for FNAC (32%), followed by breast (29%), thyroid (22%), and salivary gland (2%). Other site comprised 15% of cases. In lymph node, reactive lymphadenitis was the most common benign lesion (42.7%) and metastatic squamous cell carcinoma was the commonest malignant lesion(12.62%). In breast, benign proliferative breast disease was the most common(84.1%) and ductal carcinoma was commonest among malignant lesions(8.5%). Among thyroid lesions, benign proliferative thyroid disease was the commonest one (47.9%)followed by papillary carcinoma among malignant lesions(11.3%).Among salivary gland lesions, Chronic sialadenitis was common inflammatory lesion (37.5%) followed by pleomorphic adenoma among benign lesions(25%) and carcinoma comprised 25%. Lipoma was the commonest lesion ( 63%) from other sites. Conclusion: Wide range of lesions, both benign and malignant, can be diagnosed by FNAC thus restricting surgery to cases only requiring further histopathological evaluation. DOI: http://dx.doi.org/10.3126/mjsbh.v9i2.5022 Medical Journal of Shree Birendra Hospital Vol.9(2) 2010: 25-29  

scholarly journals Positive predictive value of BIRADS (Breast imaging reporting and data system) IV lesions in detection of carcinoma breast, using histopathology as a gold standard.

2020 ◽  
Vol 27 (01) ◽  
pp. 172-179
Author(s):  
Syed Anjum Mehdi ◽  
Hassan Bukhari ◽  
Irfan Shabbir ◽  
Sobia Shabbir
Keyword(s):  
Positive Predictive Value ◽  
Predictive Value ◽  
Gold Standard ◽  
Breast Imaging ◽  
Benign Lesion ◽  
Malignant Lesion ◽  
Performance Outcomes ◽  
Duration Of Symptoms ◽  
Carcinoma Breast ◽  
The Mean

Objective: To determine the Positive Predictive Value of BIRADS IV lesions in detection of carcinoma breast, using histopathology as a gold standard. Study Design: A Cross-Sectional study. Setting: Department of Radiology Allied Hospital Faisalabad. Period: From 01-09-2015 to 01-03-2016. Material & Methods: 93 female patients referred to radiology department were included after taking consent. Data were collected on structured proforma. The final diagnosis of the BIRASDS IV lesion seen on mammography has made by consultant. Then patients were sent for biopsy. Mammographic diagnose was then compared with the histopathological diagnose by consultant. The primary performance outcomes of diagnostic mammography like sensitivity, specificity and accuracy were evaluated. Results: The mean age of patients was 45.96±7.85years. There were 19 females had subcategory A, 22 had subcategory B and 52 females had subcategory C. The mean size of lump was 3.23±0.69cm. The mean duration of symptoms was 3.97±3.43months. On BIRADS IV, malignant lesion detected in 71 (76.3%) females while 22 (23.7%) females had benign lesion. On histopathology, malignant lesions detected in 50 (53.8%) females while 43 (46.2%) females had benign lesion. Findings of BIRADS IV were compared with histopathology and the PPV was 43.7% and NPV was 13.6%. Conclusion: Through findings of this study, we concluded that in comparison to histopathology, BIRADS IV had PPV of 43.7% and NPV of 13.6%. In some cases, we can rely on BIRADS-IV and skip interventional method including biopsy for diagnosis of breast lesion.

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