Leg and arm adiposity is inversely associated with diastolic hypertension in young and middle-aged United States adults

Background We sought to determine the association between appendicular adiposity and hypertension, with the purpose of better understanding the role of body fat distribution on blood pressure (BP). Methods We included 7411 adults aged 20 to 59 who were not taking antihypertensives and without cardiovascular disease from the 2011 to 2018 National Health and Nutrition Examination Surveys. Leg & arm adiposity, determined via dual-energy X-ray absorptiometry scans, was defined as percent of total body fat present in legs/arms (leg/total%, arm/total%). Measures were categorized into sex-specific tertiles. We estimated change in BP and odds ratios (ORs) of hypertension (BP ≥ 130/80) and hypertension subtypes using multivariable, survey design-adjusted linear & logistic regression, respectively. Results Of the participants, 49% were female, the average (standard deviation) age was 37.4 (0.3) years, and 24% had hypertension. Those in the highest tertile (T3) of leg/total% had 30% decreased adjusted ORs (aOR) of hypertension compared to the lowest tertile (T1; aOR, 0.70; 95% confidence interval [95% CI], 0.55–0.89). This association was not significant for arm/total% (0.89, 0.68–1.17). T3 of leg/total% was associated with 49% lower, 41% lower, and unchanged relative odds of isolated diastolic hypertension (IDH), systolic-diastolic hypertension (SDH), and isolated systolic hypertension (ISH) compared to T1 (IDH: 0.51, 0.37–0.70; SDH: 0.59, 0.43–0.80; ISH: 1.06, 0.70–1.59). For every 10% increase in leg/total%, diastolic BP decreased by an adjusted mean 3.5 mmHg (95% CI, − 4.8 to − 2.2) in males and 1.8 mmHg (95% CI, − 2.8 to − 0.8) in females (P < 0.001 for both). Conclusions A greater proportional distribution of fat around the legs is inversely, independently associated with hypertension, and more specifically, diastolic hypertension (IDH and SDH).

Research of the Modes of Starting and Braking during Work of the Systems of Group Electric Drive of Mine Electric Locomotive with the Different Types of Electric Engines

In the article the results of research of work of mine electric locomotive are driven on condition of stability of the system "A wheel is a rail" on coupling of wheels of electric locomotive with rails. It is marked that work of mine electric locomotive transport is conditioned by the row of specific terms. It is indicated that for realization of the electromechanics systems of mine electric locomotives structures are used with the hauling electric engines of direct and variable current. During working as of mine electric locomotive an important question there is coupling of wheels of electric locomotive with rails. Investigation of worsening of coupling of wheel with a rail is an origin of processes of skidding in the mode of creation of tractive or юза force in the mode braking of electric locomotive, that influence negatively for other knots of hauling electromechanic. In turn stability of the system "A wheel is a rail" depends on the type of hauling electromechanic. At consideration condition of stability of electromechanic on coupling of wheels of electric locomotive with rails important is inflexibility of descriptions of hauling electric motors. What more inflexibility, the higher stability of the system "A wheel is a rail". More hard descriptions can be got in the system of electromechanic with hauling asynchronous engines that give an opportunity to use this fact for realization of proportional distribution of efforts between the wheelpairs of electric locomotive. The systems ticker-coil on speed allow to carry out distribution of hauling and brake efforts that is attached to the wheelpairs of electric locomotive, in accordance with distribution of efforts from these wheelpairs on rails, only after the beginning of processes of skidding or skidding. For the decision of this problem a sufficient condition there is a limit of currents of hauling electric motors on the set level. In this connection possibility of distribution of hauling and brake efforts appears at any moment to time. For the decision of task of rational distribution of efforts of electric locomotive, distribution of forces was analysed between his wheelpairs in the function of total force that pulls an electric locomotive on his coupling. On the basis of analysis an idea was got about the redistribution of loading on the axes of electric locomotive. This distribution is in direct ratio to his total tractive force and coupling height, and in inverse ratio to inflexibility of corps. As a result, in order that propelling and brake forces on the axes of electric locomotive corresponded to distribution of weight on rails on wheelpairs, it is necessary to support identical correlation of weight and efforts on the axes of electric locomotive. The design of transients was conducted in the system of group electric hauling drive of mine electric locomotive in the mode of starting and braking. A design is executed for the engine of direct-current with successive connection of poles and hauling asynchronous engine. The charts of transients in the system of group electric hauling drive of mine electric locomotive in the mode of starting and braking showed absence of processes of skidding and slipping at application of the offered principle for the control system.

PSVIII-3 Genetic evaluation for Hereford breed in Kazakhstan

For effective management of animal breeding, complete, high-quality and reliable information about an individual animal, about the population as a whole, is required. For breeding work, it is necessary to select breeding bulls, the offspring of which have high productivity. The selection of ancestors and offspring of bulls makes it possible to consolidate or consolidate these traits. The aim of the research is to improve the methodology for beef cattlegenetic evaluation. Material and methodology. Beef cattle genetic evaluation implemented by BLUP (Best Linear Unbiased Prediction). Mixed linear biometric models (AM / MME) were built for each assessed productive trait: Birth Weight, Weaning Weight, Milking at Calf Weaning, Yearling Weight. 74,868 animals of the Hereford breed. Percentages describe 5% and 10% share distributions of index values. The EPD values of live weight at birth in 90% of cases lie in the range from “-8.76” to “+18.21”; for live weight at weaning in the range from “-35.73” to “+42.83”; for live weight per year from “-51.45” to “+90.18”. The best and lowest EPD values are in 10% edge intervals relative to the entire set of calculated estimates. The proportional distribution of EPD accuracy in 2020 for the productive indicators of animals born in the period 2014–2020 of the Hereford breed have zero values up to 10%. The smaller number of fractions of non-zero values of the CPI accuracy indicates a more complete and qualitative filling of the database with productive indicators of live masses in recent years. In Kazakhstan, a method for calculating EPD by the BLUP AM method was developed with the construction of a genetic model of an animal and EPDs were calculated according to 5 productive indicators: live weights at birth, at weaning, at 12 months. age, adult animal (age 5 years) and milk production of cows.

The Consequence of the Legal Application of Forest Area Defense Principles and Approval Principles

Law Number 11 of 2020 concerning Job Creation is believed to be able to save Indonesia because it is considered to be able to create jobs, assist small business actors, streamline regulations in terms of numbers and simplify regulations to make them more targeted. On the other hand, the job creation law is considered to be detrimental to many groups, such as workers such as laborers, fishermen, and farmers who are also considered to only provide benefits to entrepreneurs. Law Number 11 of 2020 with new rules and amendments to Article 18 and Article 19 of Law Number 41 of 1999 concerning Forestry. In Law Number 41 of 1999 concerning Forestry, it is regulated that changes in the allocation and function of forest areas are determined by the Government based on the results of integrated research. Second, the area offorest that must be maintained is at least 30% (percent) of the area of river watersheds and/or islands with a proportional distribution. However, in the Job Creation Law the minimum figure of 30% (thirty percent) is no longer mentioned in the amendment article and the abolition of provisions related to the DPR’s authority in giving approval for the transfer of functions/changes in forest areas. This paper aims to find out the principles that have been violated and the legal consequences of applying the article. The research method used in this research is the type of normative legal research. The results of this study indicate that there are deviations from the land principle and the principle of consent which can cause the norms contained in Article 18 paragraph (2) and Article 19 paragraph (2) of Law Number 11 of 2020 to be less enforceable. The abolition of the minimum area of forest area and the abolition of the DPR’s authority to approve the transfer of functions/changes to forest areas, will have the potential to provide greater opportunities for deforestation.

State Responsibility and Its Distributive Effect

This chapter presents the problem of the distributive effect and its treatment in existing literature. Starting with the idea that states are corporate moral agents, it suggests that states are morally responsible for their wrongdoings in two distinct senses: they can be blameworthy when they act wrongly, and they incur remedial responsibilities to address the wrong, including paying compensation to its victims. The chapter then contrasts two core views on how the state’s remedial responsibilities should be distributed among its members. The first view supports a proportional distribution, which tracks the state’s members’ blameworthy contributions to their state’s wrongdoings. While this approach caters to individualist intuitions about fairness, it is hard to implement in real-world states. The second approach is nonproportional, and lets the burden fall on the population at large. While easier to implement, it seems to lack a solid normative justification.

Intentional Participation and Nonproportional Distribution

This chapter develops a justification for a nonproportional distribution of a group’s remedial liabilities for its wrongdoings. The justification is grounded in the group members’ participation in their group. Drawing on Christopher Kutz’s model of collective action, it suggests that people participate in a group act when they have a participatory intention in take part in the act. It then argues that when people intentionally participate in collective action, they incur the duty to accept a nonproportional share of the burdens that flow from that action, in circumstances where a proportional distribution is not feasible or is very costly. However, there are limits to this obligation: it arises only when the group members’ participatory intentions are genuine, and not forced on them against their will.

Loss of years of healthy life due to road incidents of motorcyclists in the city of Medellin, 2012 to 2015

Objective Determine the loss of years of healthy life due to road incidents of motorcyclists in the city of Medellin from 2012 to 2015. Methods Descriptive study with data on health care of injured motorcyclists and deaths adjusted with the Preston and Coale method, and OPS proportional distribution for the period 2012–2015. The years of life lost due to premature death (YLLs), years lived with disability (YLDs), and the disability-adjusted life years (DALYs) were calculated according to the new methodology designed for that purpose. Results The loss of years of healthy life due to road incidents of motorcyclists in the four-year period was 80,046 DALYs (823.8 per 100,000 inhabitants), with a higher proportion in men (81.3% and a ratio of 5 to 1 compared to women); the YLDs was 66.6% with marked differences in favor of men. There was nearly a 38% difference in the ages of 15 to 19 as well as a 19% difference from 30 to 49, compared to women. Premature death (YLLs) contributed to 33.4% of DALYs, with significant presentation in the above-mentioned age groups. Conclusions The greatest loss of years of healthy life due to road incidents of motorcyclists in Medellin was due to non-fatal injuries and was concentrated in young men. If the trend of motorcycle road incidents continues, both local and national road safety plans will fail to accomplish the expected results, especially among motorcycle users.

Push Plate Test of CRTS II Slab Ballastless Track: Theoretical Analysis, Experiments, and Numerical Simulation

Push plate test is a powerful tool to evaluate the interfacial bond performance of China railway track structure type-II slab ballastless track structure (CRTS II SBTS). However, there is still a lack of theoretical explanation of the push plate test. In this paper, a linear proportional distribution method is proposed in terms of a series of analytical formulas to describe the interfacial force-displacement variation of CRTS II SBTS in different damage stages of the horizontal push plate test. The force-displacement relationship established by the linear proportional distribution method agrees well with that observed in full-scale test. The horizontal push plate test is then simulated, in which a bilinear cohesive zone model (CZM) was adopted to simulate the interface within track structure. The parameters of the CZM are calculated based on the force-displacement curves obtained from scale push plate test. Particularly, the normal cohesive parameters are determined based on the scale vertical push plate test instead of the traditional splitting tensile test. The simulation proves that both the maximum affected length in the undamage stage and the maximum damaged length in the damage stage depend rather on the interfacial stiffness and the material parameters of SBTS than the horizontal load. These two lengths given by the simulation are close to those defined by the proposed linear proportional distribution method. This indicates the reliability of the proposed method and the capability of scale push plate test in determining cohesive parameters.

IMPROVING METHODOLOGICAL APPROACHES IN THE IMPLEMENTATION OF GROSS REGIONAL PRODUCT

The article is devoted to the issues of improving methodological approaches to calculating the gross regional product (GDP), which is one of the main indicators of the regional accounting system, and to the study of its impact on economic growth. First of all, the basics of the regional economy and sources of information in this area are studied. The research results can be used to assess regional structures, taking into account the sectoral parameters of their development, as well as in the process of proportional distribution of investments in the regions