PREVALENCE OF DIABETIC RETINOPATHY AMONG CHILDREN WITH TYPE 1 DIABETES MELLITUS TREATED BY INSULIN

2021 ◽  
pp. 64-65
Author(s):  
Dinesh Kumar ◽  
Chanchal Gupta ◽  
Mahesh Kumar Gupta ◽  
Vishnu Agarwal
Keyword(s):  
Diabetic Retinopathy ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetic Children ◽  
The Mean ◽  
Type 1 Dm

BACKGROUND- This study to nd out the prevalence of diabetic retinopathy (DR) among diabetic children with type 1 DM treated with insulin. METHODS -This is a cross-sectional study conducted on 100 children with type 1 DM from 1 to 16 years of age. All patients were subjected to full fundus examination and were then classied according to its results into patients with DR and patients without DR. RESULTS- The mean age of the patients was 9.42±1.31 years and 56.00% were males. DR was found in 10 (10.00%) patients, seven of whom had retinopathy in one eye and three had retinopathy in both eyes. Mild nonproliferative DR was found in 11 eyes and moderate DR was found in 2 eyes. CONCLUSION- The prevalence of DR was 10.0% among all studied patients and 6.50% among all studied eyes. The grade of retinopathy was directly related to the duration of DM, fasting blood glucose, and glycosylated hemoglobin levels.

scholarly journals PREVALENCE OF DIABETIC RETINOPATHY AMONG CHILDREN WITH TYPE 1 DIABETES MELLITUS

2021 ◽  
Vol 5 (8) ◽  
Author(s):  
Shakti Krishan Rajguru ◽  
Jasraj Bohra
Keyword(s):  
Diabetic Retinopathy ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Cross Sectional Study ◽  
Moderate Degree ◽  
Cross Sectional ◽  
Mild Degree ◽  
Diabetic Children ◽  
Type 1 Dm

Background: This study to find out the prevalence of diabetic retinopathy (DR) among diabetic children with type 1 DM treated with insulin. Methods: This is a cross-sectional study conducted on 50 children with type 1 DM from 1 to 14  years of age. All patients were subjected to full fundus examination and were then classified according to its results into patients with DR and patients without DR. Results: A total of 6 (12.0%) patients were found to have DR. 5 patients had retinopathy in one eye and 1 patients had retinopathy in both eyes. Thus, the total number of eyes with retinopathy was 7 of 100 screened eyes (7.00% of all eyes). Most eyes with retinopathy had a mild degree of NPDR, as it was present in 6 eyes. The other 1eyes had moderate degree of retinopathy Conclusion: The prevalence of DR was 12.0% among all studied patients and 7.00% among all studied eyes. The grade of retinopathy was directly related to the duration of DM, fasting blood glucose, and glycosylated hemoglobin levels. Keywords: DM, DR, Hb1Ac

scholarly journals Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study

2018 ◽  
Vol 6 (4) ◽  
pp. 104 ◽  
Author(s):  
Veena H. R. ◽  
Sribhargava Natesh ◽  
Sudhir Patil
Keyword(s):  
Diabetic Retinopathy ◽  
Serum Creatinine ◽  
Glycated Haemoglobin ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chronic Inflammatory Condition ◽  
The Mean

Periodontal disease (PD), a chronic inflammatory condition characterized by destruction of the supporting tissues of the teeth, increases the risk of complications in diabetics. Diabetic retinopathy (DR) is a microvascular complication of prolonged hyperglycaemia. There appears to be a similarity in the pathogenesis of DR and PD. Hence, this study aimed to investigate the association, if any, between DR and PD, correlate the severity of DR with the severity of PD, and investigate the association between glycated haemoglobin (HbA1c), serum creatinine and periodontal variables. The periodontal status of 200 adult diabetic patients in the age group of 30–65 years with varying severity of DR was assessed. Evaluation of the severity of PD was assessed by recording clinical parameters. Haematological investigations including glycated haemoglobin (HbA1c) and serum creatinine were estimated before the initiation of treatment for DR. A statistically significant association between the mean duration of diabetes mellitus (DM) and the severity of DR and PD was found. The severity of PD was directly correlated with the severity of DR. There was a significant association between the levels of HbA1c and serum creatinine and severity of DR and PD. There could be a plausible relationship between DR and PD. Further prospective studies on a larger population with longer follow-ups are required to ascertain whether PD and its severity directly affect the progression and severity of DR.

Is type 1 diabetes mellitus associated with ABO & Rh blood groups? A cross-sectional study

2022 ◽  
Author(s):  
Mahtab Ordooei ◽  
Nasim Namiranian ◽  
Saeedeh Jam-Ashkezari ◽  
Hadi Jalali ◽  
Azam Golzar
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Blood Group ◽  
Cross Sectional Study ◽  
Blood Groups ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Background: This study was conducted to determine whether type 1 diabetes mellitus (T1DM) is associated with ABO & Rhesus (Rh) blood groups. Materials and Methods: This analytical cross sectional study was carried out on 77 patients suffering from T1DM and 96 healthy children less than 18 years old referring to Yazd Diabetes Research Center from April 2018 to May 2019. The ABO blood group and Rh factor in both groups were determined. Fasting blood sugar (FBS) and hemoglobin A1C (HbA1c) were measured at baseline, 12 weeks, and 24 weeks in these patients, and the mean of FBS and HbA1C in three-time assessments were considered as the FBS and HbA1C variables. The statistical analysis was performed by SPSS software version 22. Results: About 46.8% in T1DM and 36.5% in the control groups were male. There was a significant difference between groups regarding blood groups (p-value: 0.042). Although the frequency of B+ was 33.8% and 19.8% in the T1DM and controls, respectively, AB+ and O+ were more prevalent in the controls. The mean of FBS was significantly different between groups (p-value: 0.023). Conclusions: The findings revealed that patients with blood group B are more likely to develop T1DM whereas those with blood group O showed a lower tendency towards diabetes.

scholarly journals Role of Oxidative Stress and Severity of Diabetic Retinopathy in Type 1 & Type 2 Diabetes

2021 ◽  
Author(s):  
Kholoud Albokhary ◽  
Feda Aljaser ◽  
Manal Abudawood ◽  
Hajera Tabassum ◽  
Afnan Bakhsh ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Retinopathy ◽  
Cross Sectional Study ◽  
Antioxidant Defenses ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
The Status ◽  
Type 1 Dm

Background: Diabetic retinopathy (DR) is a sight-threatening complication of diabetes mellitus (DM). Oxidative stress generated on account of hyperglycemic state may lead to retinal abnormalities including DR. Objectives : To evaluate the status of antioxidant enzymes -superoxide dismutase (SOD) and catalase (CAT); with different stages of DR severity in subjects with type 1 and type 2 DM. Methods: The cross-sectional study enrolled 148 subjects with type 1 DM (n=17); type 2 DM (n=96) and non-diabetes controls (n=35). Subjects with DM were divided into two subgroups based on DR severity (mild-to-severe non-proliferative DR and proliferative DR [PDR]) and Serum glycated hemoglobin (HbA1c), lipid profile, SOD and CAT were estimated. Results: Both SOD and CAT levels were lower in diabetes subjects than non-diabetic controls. A significant positive correlation was found between HbA1C level and severity of DR (P<0.0001). Levels of SOD and CAT varied significantly with DR severity in both diabetic groups at p<0.05. Furthermore, levels of SOD and CAT was found to decrease significantly (P<0.001) in DR (+) compared to DR (-) patients. Also, increased levels of HbA1c was significantly associated (P<0.001) with decreased SOD in both subgroups (NPDR and PDR). DR severity was significantly associated with SOD and CAT in the NPDR and PDR subgroups (P<0.05). Conclusion: Oxidative stress and decreased antioxidant defenses are associated with DR progression to its PDR stage.

scholarly journals High Glycosylated Haemoglobin Increase Prevalence of Proliferative Diabetic Retinopathy

2019 ◽  
Vol 1 (5) ◽  
Author(s):  
Ni Made Ari Suryathi ◽  
I Putu Budhiastra ◽  
I W.G. Jayanegara
Keyword(s):  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Glycosylated Hemoglobin ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Past ◽  
High Prevalence ◽  
High Level ◽  
First Time

Diabetic retinopathy (DR) is one of the microvascular complication in diabetes mellitus (DM). Glycosylated hemoglobin (HbA1c) is an indicator that reflects the percentage of blood glucose tied to hemoglobin for the past three months. This study aims to determine if a high level of HbA1c increases the prevalence of proliferative diabetic retinopathy. Cross-sectional study. The participants were DM patients who were diagnosed with PDR and NPDR for the first time and HbA1c level was checked in the laboratory. Of the 74 participants, 37 participants were PDR, and 37 participants were NPDR. The ratio of prevalence (PR) was 3.87, with Confident of Interval (CI 95%): 1.96-7.67 and p < 0.001. Multivariate analysis shows Odd Ratio (OR) of HbA1c is 18.319 (5.334-62.919) and p < 0.001. High level of HbA1c as a risk factor of high prevalence of PDR.

scholarly journals Glycemic Control and Knowledge among Children and Adolescents with Type 1 Diabetes Mellitus; A Cross-sectional Study

2021 ◽  
Vol 2 (1) ◽  
pp. 1-9
Author(s):  
Nosaiba Ahmed Hussein Abdelseed
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Glycemic Control ◽  
Type 1 Diabetes Mellitus ◽  
Children And Adolescents ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetic Children

Purpose: The aim of this study is to evaluate the long-term glycemic control by glycosylated hemoglobin level (HbA1c) and to assess knowledge about the diabetic regimen. The results of glycemic control in this study were compared with the results of a study conducted in 2018 that targeted almost a similar population. Study Design: A Cross-Sectional Study. Subjects and Methods: The study was conducted in October 2012 to December 2012 in a major referral Diabetic Centre. Diabetic children aged 8 to 18 years old who were attending the referral diabetic clinics were included in the study (n = 90). Knowledge of diabetes management was evaluated by using a semi-structured questionnaire and HbA1c results were obtained from medical records, available for only 71. Later, these Glycated Hemoglobin HbA1c results were compared with the results of a recent study carried out among Sudanese diabetic children and adolescents in 2018. Results: Out of 71 diabetic children 78.9% were of poor glycemic control with mean HbA1c 10.36±2.14. On the other hand, the majority had good knowledge about the diabetic treatment including insulin administration, its storage conditions, and also the effect of exercise on blood glucose. However, almost 18.8% of studied participants did not know hypoglycemia symptoms, and about 11% of these patients were unaware of hypoglycemia management. Conclusion: The study has indicated that a significant percentage of studied diabetic children and adolescents had poor glycemic control. Although children’s knowledge about insulin therapy was good, further study must be conducted to investigate factors related to glycemic control among children with type 1 diabetes mellitus (T1DM).  

scholarly journals PREVALENCE OF VITAMIN D DEFICIENCY IN TYPE 1 DM A CONTROL CROSS SECTIONAL STUDY HELD IN MIDDLE AND WEST REGIONS OF SAUDI ARABIA.

2017 ◽  
Vol 5 (2) ◽  
pp. 1321-1325
Author(s):  
OlfatZ. Sambas ◽  
◽  
AhmadZ. Makeen ◽  
AmmarS. Yamani ◽  
AlaaA. Alghamdi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Saudi Arabia ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 1 Dm
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