scholarly journals “DENGUE ENCEPHALITIS – A RARE MANIFESTATION OF DENGUE FEVER.”

2020 ◽  
pp. 1-2
Author(s):  
Showkat Nazir Wani ◽  
Anish Garg Atul Kaushik ◽  
Atul Kaushik ◽  
Naveen Tariq
Keyword(s):  
Cerebrospinal Fluid ◽  
Differential Diagnosis ◽  
Dengue Fever ◽  
High Grade ◽  
High Grade Fever ◽  
Altered Sensorium ◽  
Mri Brain ◽  
Northern India ◽  
Rare Manifestation ◽  
History Of

We report a case of dengue fever with features of encephalitis from Northern India. A 22 years female presented with history of high-grade fever with chills for 2 days followed by altered sensorium and MRI brain, revealed characteristic changes consistent with Encephalitis with hemorrhage mainly involving the bilateral thalami. The diagnosis of dengue was confirmed by the presence of dengue antigen in the serum and the presence of dengue antibodies in the serum as well as cerebrospinal fluid. Dengue is not primarily a neurotropic virus and encephalopathy is an uncommon finding in dengue. This case explains the importance of considering dengue encephalitis as the differential diagnosis of fever with altered sensorium, especially in countries like India where dengue is rampant.

scholarly journals Hemichorea-hemiballismus in a patient with hyperglycaemic hyperosmolar state

2020 ◽  
Vol 8 (10) ◽  
pp. 3710
Author(s):  
Rifkatu S. Reng ◽  
Odumodu Kenechukwu ◽  
Shuaibu Ramatu ◽  
Oyakhire Shyngle ◽  
Omonua Special ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Involuntary Movement ◽  
Rare Complication ◽  
Cerebral Atrophy ◽  
Lower Limbs ◽  
High Grade Fever ◽  
Rare Manifestation ◽  
History Of ◽  
Hypertensive Woman ◽  
The Right

Hemichorea-hemiballismus (HCHB) is a rare manifestation of hyperglycaemic hyperosmolar state caused by contralateral lesion in basal ganglia. A 74-year-old, known diabetic and hypertensive woman presented with one-week history of high-grade fever and loss of consciousness associated with involuntary movement of the right upper and lower limbs for 10 hours prior to presentation. Physical examination revealed pyrexia, tachycardia and altered sensorium. Blood glucose was 53.8 mmol/l, hemoglobin A1c (Hb A1c) 9.9% and brain computed tomography (CT) scan showed cerebral atrophy with bilateral basal ganglia hyperdensities. Escherichia coli was cultured from the urine. She did well on treatment with soluble insulin, rehydration and intravenous ceftriaxone. HCHB is a rare complication seen in patients with poorly controlled diabetes mellitus. This report highlights the reversibility of the disease with prompt diagnosis and appropriate insulin treatment. HCHB should be distinguished from other intracranial pathologies.

scholarly journals COVID-19 and Dengue infection in Bangladesh: a case of coinfection where hemoptysis as first presentation

2021 ◽  
Author(s):  
Mohammad Ashraful Amin ◽  
Md. Taufiqul Islam ◽  
Ishtiakul Islam Khan ◽  
Zahid Hasan Khan ◽  
Firdausi Qadri ◽  
...  
Keyword(s):  
Dengue Fever ◽  
Sore Throat ◽  
Dengue Infection ◽  
High Grade ◽  
Rt Pcr ◽  
High Grade Fever

Bangladesh recently faced large outbreaks of both COVID-19 and Dengue fever. A 28-year-old woman suffered from symptoms including hemoptysis as first presentation followed by high-grade fever, sore throat, and fatigue. SARS-CoV-2 was confirmed by RT-PCR and also diagnosed dengue later on.COVID-19 and dengue fever could be a harmful combination.

Acute ophthalmoplegia in a patient with anti-GQ1b antibody and chronic facial diplegia

2020 ◽  
Vol 13 (7) ◽  
pp. e234319
Author(s):  
Fanny Huynh Du ◽  
Alexan Yerevanian ◽  
Matthew Shtrahman
Keyword(s):  
Cerebrospinal Fluid ◽  
Differential Diagnosis ◽  
Elevated Serum ◽  
Miller Fisher Syndrome ◽  
Igg Antibody ◽  
Fisher Syndrome ◽  
Facial Diplegia ◽  
History Of ◽  
Insight Into ◽  
Tendon Reflexes

A 56-year-old man with a remote history of bilateral recurrent facial palsies presented with a week of ophthalmoplegia with intact deep tendon reflexes and lack of ataxia, cerebrospinal fluid with albuminocytologic dissociation and elevated serum anti-ganglioside Q1b (GQ1b) IgG antibody. We diagnosed the patient with acute ophthalmoplegia without ataxia, a condition under the spectrum of anti-GQ1b antibody syndromes which also includes Miller Fisher syndrome. Given the rarity of recurrent facial palsies and anti-GQ1b antibody syndromes as well as reports associating facial palsies and this syndrome, we suggest that our case may be an unusual presentation of an anti-GQ1b antibody syndrome beginning with recurrent facial palsies several years prior to ophthalmoplegia. Prior studies of human nerves provide insight into the pathophysiology, including ganglioside distribution and cross-reactivities underlying the heterogeneity of anti-GQ1b antibody syndromes. This report may expand the differential diagnosis in patients with recurrent facial palsies and broaden the phenotype of anti-GQ1b syndromes.

scholarly journals Meningoencephalitis case with listeriosis etiology in an immunocompetent female patient

2020 ◽  
Vol 25 (1) ◽  
pp. 41-44
Author(s):  
Olga N. Domashenko ◽  
Vitaliy A. Gridasov
Keyword(s):  
Cerebrospinal Fluid ◽  
Listeria Monocytogenes ◽  
Mortality Rate ◽  
High Grade ◽  
High Grade Fever ◽  
Once Daily ◽  
Clinical Variant ◽  
Listeria Meningitis ◽  
Wrist Flexors ◽  
Fluid Test

Nervous forms of listeriosis are observed in 5%10% of persons suffering from this disease and in 75% of children with bacteriologically confirmed listeriosis as well. The most widespread clinical variant is Listeria meningitis, making up 15% of all cases of bacterial and serous meningitides. The mortality rate at neurolisteriosis reaches 30%40%. A case of acute meningoencephalitis associated with Listeria monocytogenes 4b in a 37-year-old immunocompetent woman is described. The disease was characterized by subacute onset, manifested intoxication, long-lasting and high-grade fever, cerebral coma, bulbar syndrome, right-side hemiparesis, bilateral hypertonus of the wrist flexors, strabism, anisocoria, manifested leukocytosis with leukocyte formula stab shift, ESR 4559 mm/hour. Cerebrospinal fluid test: cytosis 663 сells in 1 mcl, neutrophils 79%, lymphocytes 21%, protein 1451 mg/l, glucose 3.8 mmol/l. Diagnosis had been confirmed with detection of IgM against Listeria monocytogenes 4b in liquor using the indirect immunofluorescence reaction and Listeria monocytogenes by means of PCR. Antibacterial therapy had been conducted using Meropenem, Ampicillinum, endolumbal administration of 4 mg once daily of Gentamycinum combined with intravenous administration of 24 million of units/day of Penicillin. On day 50, she was transferred for rehabilitation treatment to the Department of Neurology.

A Case of Illegal Septic Abortion Leading to Maternal Mortality

2010 ◽  
Vol 2 (2) ◽  
pp. 149-151 ◽  
Author(s):  
SA Inamdar ◽  
Neharika Malhotra ◽  
S Sirsam
Keyword(s):  
Biochemical Parameters ◽  
Severe Pain ◽  
Clinical Presentation ◽  
Rural India ◽  
High Grade ◽  
High Grade Fever ◽  
Incomplete Abortion ◽  
History Of ◽  
Wooden Stick ◽  
Septic Abortion

ABSTRACT A 26 years old female G3P2L2 with a previous LSCS done 10 months back, with 15 weeks twin gestation and history of criminal abortion by quack with a wooden stick brought to us in a moribund state with complaints of high grade fever with severe pain in abdomen associated with nausea and vomiting that morning. Clinical examination revealed incomplete abortion with features of sepsis. After evaluation a diagnosis of septic abortion was established based on the clinical presentation and biochemical parameters. This case is being reported for the increased incidence of illegal unsafe abortions in rural India despite legalizations of abortion.

scholarly journals Chagasic meningoencephalitis: case report of a recently included AIDS-defining illness in Brazil

2004 ◽  
Vol 46 (4) ◽  
pp. 199-202 ◽  
Author(s):  
Geraldine Madalosso ◽  
Alessandra C. Guedes Pellini ◽  
Marileide J. Vasconcelos ◽  
Ana Freitas Ribeiro ◽  
Leonardo Weissmann ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cerebrospinal Fluid ◽  
Differential Diagnosis ◽  
Case Report ◽  
Hospital Admission ◽  
Chagas Disease ◽  
Direct Examination ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Previous Disease

Recently, reactivation of Chagas disease (meningoencephalitis and/or myocarditis) was included in the list of AIDS-defining illnesses in Brazil. We report a case of a 52-year-old patient with no history of previous disease who presented acute meningoencephalitis. Direct examination of blood and cerebrospinal fluid (CSF) showed Trypanosoma cruzi. CSF culture confirmed the diagnosis. Serological assays for T. cruzi and human immunodeficiency virus (HIV) were positive. Despite treatment with benznidazol and supportive measures, the patient died 24 hours after hospital admission. In endemic areas, reactivation of Chagas disease should always be considered in the differential diagnosis of meningoencephalitis among HIV-infected patients, and its presence is indicative of AIDS.

scholarly journals Adult onset still's disease: a rare disorder

2018 ◽  
Vol 6 (8) ◽  
pp. 2841
Author(s):  
Belema O. Abbey ◽  
Dasetima D. Altraide ◽  
Bolaji I. Otike-Odibi
Keyword(s):  
Immune Dysregulation ◽  
High Grade ◽  
Adult Onset ◽  
High Grade Fever ◽  
Therapeutic Decisions ◽  
History Of ◽  
Patient Stay ◽  
Clonic Seizures ◽  
Systemic Symptoms ◽  
Systemic Onset

Adult onset disease is a variant of systemic onset juvenile idiopatic arthritis characterised by seronegative poly arthritis in association with multi systemic inflammation. it is often seen in young adults. Authors have report a case of a 28 year old male who presented to us with a predominantly systemic symptoms. patient presented with a 6 month history of high grade fever, with associated recurrent joint pains, sore throat, generalized tonic-clonic seizures and skin rashes. Patient remained markedly ill for most of his in-patient stay. Aesilogy is unknown, though it is currently thought that there is interplay between a genetic predisposition, an immune dysregulation and environmental play mainly infectious. Therapeutic decisions should be based on the extent and severity of organ involvement.

scholarly journals Chikungunya Outbreak from 1952-2019: A Prospective to Cope-Up with this Re-emerging Disease

2020 ◽  
Vol 11 (4) ◽  
pp. 11724-11736
Keyword(s):  
Dengue Fever ◽  
Human Population ◽  
Review Article ◽  
Emerging Disease ◽  
High Grade ◽  
High Grade Fever ◽  
Study Results ◽  
The Family ◽  
Heavy Burden ◽  
The Common

Chikungunya is a mosquito-borne disease caused by the alphavirus that belongs to the family Togaviridae. It was first identified in 1952 when the first outbreak of chikungunya occurred in the Tanganyika. From them, several outbreaks had been taken place around the globe, making a severe threat to the human population. High-grade fever, nausea, and body pain mislead the disease with Dengue fever. Disease effects are long-lasting; the disease is characterized by severe joint pains, which leads to arthralgia. To date, no direct treatment is available for the infection, which puts a heavy burden on society. In this review article, the authors focus on the outbreaks of chikungunya since1952 to 2019 worldwide. The mutations occurred in the proteome of chikungunya. The evolution occurred because of those mutations and their effects on human societies. The study results that the two mutations in the proteome made the species more vulnerable to society. The outbreak study suggests that numerous chikungunya cases had been identified worldwide with the common symptoms that turn severe with these mutations. This study result reveals that scientists and researchers must focus on the disease's intensity and work progressively to find the solution for this emerging disease.

High Incidence of Dengue Fever in Karachi and the Benefits of Ultrasound for Diagnosis of Complications

2020 ◽  
Author(s):  
Samia Perwaiz Khan
Keyword(s):  
Pericardial Effusion ◽  
Liver Injury ◽  
Dengue Fever ◽  
Joint Pain ◽  
High Grade ◽  
Ultrasound Scan ◽  
High Grade Fever ◽  
High Incidence ◽  
Laboratory Investigations ◽  
The Common

Background: Dengue fever presentations are from asymptomatic fever to most serious complications. Acute high-grade fever, muscle and joint pain, myalgia, skin rashes, hemorrhage and circulatory shock are the common symptoms. There has been reported increase in number of dengue fever and last few years. Urgent diagnosis is critical to avoid complications like liver injury, cardiomyopathy, pneumonia, orchitis, oophoritis, seizures and encephalopathies. This study aimed to determine the complication caused by dengue fever after the diagnosis by clinical and laboratory investigation by performing ultrasound abdomen and thorax. Methods: In this study one hundred and twenty one (121) patients diagnosed with dengue fever and laboratory investigations done from Jinnah Medical Hospital (JMH) and Pathological & Molecular Laboratories from August to November 2019. Ultrasound of abdomen and thorax was performed for diagnosing complications such as ascites, pleural and pericardial effusion through Xario-100 sonography machine. Results: Out of one hundred and twenty one (121) patients diagnosed with dengue fever forty-three (43) were found to have developed the complications such as ascites, pleural and pericardial effusion by performing ultrasound abdomen and chest. Conclusion: We found 35 % patients with dengue fever complications by ultrasound, which is most convenient diagnostic tool. Therefore, by performing early ultrasound scan of abdomen and thorax in these patients can reduce the risk of morbidity and mortality.

scholarly journals Thyrotoxic Dysphagia in an 82-Year-Old Male

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Konstantinos Parperis ◽  
Ramona Dadu ◽  
Sheikh Hoq ◽  
Vivian Argento
Keyword(s):  
Beta Blockers ◽  
Oropharyngeal Dysphagia ◽  
Barium Swallow ◽  
Graves Disease ◽  
Thyroid Function Tests ◽  
Acetyl Cholinesterase ◽  
Mri Brain ◽  
Rare Manifestation ◽  
History Of ◽  
Receptor Antibodies

Dysphagia is a common problem in elderly patients and a rare manifestation of Graves' disease. We report a case of an 82-year-old male who presented with a 4-week history of dysphagia and weight loss. Workup for his dysphagia with upper endoscopy, MRI brain, electromyography, acetyl-cholinesterase receptor antibodies, and voltage-gated calcium channel antibodies were negative. Modified Barium swallow test showed oropharyngeal dysphagia. Thyroid function tests that revealed hyperthyroidism and antibodies to TSH-receptor were positive. Based on the above findings, we considered Graves' disease as the most likely diagnosis. Patient was treated with methimazole and beta-blockers and subsequently his dysphagia resolved. This paper highlights the importance to clinicians of considering thyrotoxicosis as possible diagnosis in an elderly patient presenting with unexplained dysphagia.

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