scholarly journals PROFIL MONOUNSATURATED DAN POLYUNSATURATED FATTY ACIDS DALAM PLASMA DARAH WANITA YANG MENGONSUMSI JAMU

2020 ◽  
Vol 2 (2) ◽  
pp. 23-37
Author(s):  
Fatwa Hasbi ◽  
Endang Darmawan ◽  
Akrom Akrom

Latar Belakang : Masyarakat Indonesia diketahui gemar mengonsumsi jamu. Pada riskesdas tahun 2010 diketahui bahwa 59,12% masyarakat Indonesia mengonsumsi jamu. Jamu merupakan minuman asli Indonesia yang terbuat dari tumbuh-tumbuhan untuk tujuan pengobatan. MUFA dan PUFA banyak di temukan pada tumbuh-tumbuhan.   MUFA (Mono Unsaturated Fatty Acid) & PUFA (Poly Unsaturated Fatty Acid) merupakan golongan lemak tak jenuh yang dapat menurunkan kadar LDL serta menaikkan kadar HDL dalam darah.Tujuan : Untuk mengetahui profil monounsaturated dan polyunsaturated fatty acids dalam plasma darah wanita yang mengonsumsi jamuMetode : Penelitian ini menggunakan rancangan observasional dengan pendekatan cross sectional. Jumlah relawan dalam penelitian adalah 127 orang. Kadar MUFA & PUFA dalam plasma darah diukur menggunakan GC-MS. Hasil pengukuran kemudian dianalisis secara statistik dengan menggunakan uji distribusi frekuensi dan one-way ANOVA dengan taraf kepercayaan 95%.Hasil : Rata-rata kadar asam lemak pada  relawan yang minum jamu adalah MUFA 0,176% dan PUFA 0,012% . Jenis MUFA dan PUFA yang teridentifikasi di dalam darah relawan wanita yang mengonsumsi jamu di Kabupaten Bantul adalah Palmitoleic acid, Oleic acid (MUFA) dan Linolenic acid (PUFA). Relawan dengan nilai BMI < 18,5 (kurus) memiliki kadar MUFA yang paling tinggi dibandingkan relawan dengan nilai BMI ≥ 18,5.Kesimpulan : Ditemukan kadar MUFA yang lebih banyak dibandingkan dengan PUFA pada plasma darah relawan wanita yang mengonsumsi Jamu.  Terdapat hubungan antara kadar MUFA dengan nilai BMI.Kata kunci: MUFA, Mono Unsaturated Fatty Acid, PUFA, Poly Unsaturated Fatty Acid, Jamu.

2013 ◽  
pp. 45-50
Author(s):  
Ágnes Süli ◽  
Béla Béri ◽  
János Csapó ◽  
Éva Vargáné Visi

In the last decades many researches were made to change the animal product food’s composition. The production of better fat-compound milk and dairy products became a goal in the name of health conscious nutrition. These researches were motivated by the non adequate milk fat’s fatty acid composition. There have been made researches in order to modify the milk’s fatty acids’ composition to reach the expectations of functional foods. With the optimal supplement of the feed can be increased the proportion of the polyunsaturated fatty acids and can decreased the saturated fatty acids. Row fat content of milk was not decreasing in the course of examination neither of the cold extruded linseed nor the whole linseed supplement as opposed to observations experienced by other authors. In case of monounsaturated and polyunsaturated fatty acids when supplementing with cold extruded linseed the most significant change was observable in the concentration of the elaidic acid, oleic acid, linoleic acid, alfa-linolenic acid, conjugated linoleic acid. In case of saturated fatty acids the quantity of palmitic acid and myristic acid lowered considerably. When observating the feeding with whole linseed the concentration of many fatty acids from the milkfat of saturated fatty acids lowered (caprylic acid, capric acid, lauric acid, myristic acid, palmitic acid). The quantity of some unsaturated fatty acids was showing a distinct rise after feeding with linseed, this way the oleic acid, alfa-linolenic acid, conjugated linoleic acid, eicosadienoic acid. The aim of the study was to produce food which meets the changed demands of customers as well. The producing of milk with favourable fatty acid content from human health point of view can give scope propagate the products of animal origin.  


1965 ◽  
Vol 43 (2) ◽  
pp. 337-340 ◽  
Author(s):  
J. S. Barlow

When larvae of the parasitic fly Agria affinis (Fallén) were reared on fatty acid free diets, the characteristically high palmitoleic acid content of the body fats was much increased. Oleic acid in the diet was effective in reducing this, but not so effective as a mixture of fatty acids. The body fats still contained unusually high proportions of palmitic, palmitoleic, and oleic acids even when a mixture of fatty acids was fed. These observations are related to earlier observations on the nutritional adequacy of various fatty acids.


2009 ◽  
Vol 2009 ◽  
pp. 1-7 ◽  
Author(s):  
Ingeborg Hanbauer ◽  
Ignacio Rivero-Covelo ◽  
Ekrem Maloku ◽  
Adam Baca ◽  
Qiaoyan Hu ◽  
...  

Feeding mice, over 3 generations, an equicaloric diet in which α-linolenic acid, the dietary precursor of n-3 polyunsaturated fatty acids, was substituted by linoleic acid, the dietary precursor of n-6 polyunsaturated fatty acids, significantly increased body weight throughout life when compared with standard diet-fed mice. Adipogenesis observed in the low n-3 fatty acid mice was accompanied by a 6-fold upregulation of stearyl-coenzyme A desaturase 1 (Scd1), whose activity is correlated to plasma triglyceride levels. In total liver lipid and phospholipid extracts, the sum of n-3 fatty acids and the individual longer carbon chain acids, eicosapentaenoic acid (20:5n3), docosapentaenoic acid (22:5n3), and docosahexaenoic acid (22:6n3) were significantly decreased whereas arachidonic acid (20:4n6) was significantly increased. In addition, low n-3 fatty acid-fed mice had liver steatosis, heart, and kidney hypertrophy. Hence, reducing dietary α-linolenic acid, from 1.02 energy% to 0.16 energy% combined with raising linoleic acid intake resulted in obesity and had detrimental consequences on organ function.


2008 ◽  
Vol 52 (No. 7) ◽  
pp. 203-213 ◽  
Author(s):  
D. Schneideroá ◽  
J. Zelenka ◽  
E. Mrkvicová

We studied the effect of different levels of linseed oils made either of the flax cultivar Atalante with a high content of &alpha;-linolenic acid (612 g/kg) or of the cultivar Lola with a predominating content of linoleic acid (708 g/kg) in a chicken diet upon the fatty acid pattern in meat. Cockerels Ross 308 were fed the diets containing 1, 3, 5 or 7 per cent of oil in the last 15 days of fattening. Breast meat (BM) and thigh meat (TM) without skin of 8 chickens from each dietary group were used for analyses. The relative proportions of fatty acids were expressed as percentages of total determined fatty acids. When feeding Atalante oil, the proportions of n-6 fatty acids were highly significantly lower while those of n-3 fatty acids were higher; the ratio of n-6/n-3 polyunsaturated fatty acids in meat was narrower (<i>P</i> < 0.001) than in chickens fed oil with a low content of &alpha;-linolenic acid. In BM and TM, the relative proportions of &alpha;-linolenic and &gamma;-linolenic acids were nearly the same, the proportion of linoleic acid in BM was lower, and the proportions of the other polyunsaturated fatty acids in BM were higher than in TM. In BM, the ratio of n-6/n-3 polyunsaturated fatty acids was significantly (<i>P</i> < 0.001) more favourable than that found in TM. The relative proportions of total saturated and monounsaturated fatty acids in meat decreased and those of polyunsaturated fatty acids increased significantly (<i>P</i> < 0.01) in dependence on the increasing level of dietary oils. When feeding Atalante oil, a significant increase in the proportion of linoleic acid in BM but not in TM was observed. The proportions of the other n-6 fatty acids decreased and those of all determined n-3 fatty acids, with the exception of docosahexaenoic acid, significantly increased with the increasing level of oil in the diet. When feeding Lola oil, its increasing content in the diet increased the relative proportion of linoleic acid as well as its elongation to &gamma;-linolenic acid; however, the proportions of arachidonic and adrenic acid did not change significantly (<i>P</i> > 0.05). The proportion of &alpha;-linolenic acid increased in both BM and TM. The proportion of eicosapentaenoic and clupanodonic acids in BM significantly decreased. The ratio of n-6 to n-3 polyunsaturated fatty acids ranged from 0.9 to 13.6 and from 1.0 to 17.2 in BM and TM, respectively. An increase in the level of Lola oil in the diet by 1% caused that the n-6/n-3 polyunsaturated fatty acid ratio extended by 1.00 and 1.19 units in BM and TM, respectively. Dependences of n-6/n-3 ratio on the level of Atalante oil were expressed by equations of convex parabolas with minima at the level of oil 5.8 and 5.9% for BM and TM, respectively. By means of the inclusion of linseed oil with a high content of &alpha;-linolenic acid in the feed mixture it would be possible to produce poultry meat as a functional food with a very narrow ratio of n-6/n-3 polyunsaturated fatty acids.


2013 ◽  
Vol 80 (4) ◽  
pp. 410-417 ◽  
Author(s):  
Luming Ding ◽  
Yupeng Wang ◽  
Michael Kreuzer ◽  
Xusheng Guo ◽  
Jiandui Mi ◽  
...  

An experiment was conducted to study the seasonal changes in the fatty acid profile of milk from yaks (Bos grunniens) when kept at altitudes of 3000 m above sea level (a.s.l.) and higher. Data and samples were collected in summer (July), autumn (September), winter (November) and spring (March) from ten lactating yaks (four in spring). The yaks grazed pastures adjacent to the farm building throughout the year. In spring only they received 0·6 kg crop by-products per day (dry matter basis). Fresh alpine grasses, available in summer and autumn, showed high concentrations of α-linolenic acid (46–51 g/100 g lipids) compared with the dry, yellow vegetation of winter and spring (16 g/100 g lipids). In autumn and summer, the milk fat had higher concentrations of polyunsaturated fatty acids than in winter. These polyunsaturated fatty acids were comprised of vaccenic acid, rumenic acid and α-linolenic acid, which are all considered beneficial to human health. The rare fatty acid, γ-linolenic acid, was also detected in yak milk, especially in the milk obtained in spring. The results suggest that yak milk, which is the most important basic food of the Tibetan herders, has the most favourable fatty acid profile when yaks grazed green pasture, which also corresponds to the period of highest milk production.


1994 ◽  
Vol 31 (6) ◽  
pp. 679-688 ◽  
Author(s):  
K. G. Mandel ◽  
T. A. Bertram ◽  
M. K. Eichhold ◽  
S. C. Pepple ◽  
M. J. Doyle

This study involved a comparison of activity of several long-chain fatty acids (arachidonic acid, dihomo-[γ]-linolenic acid, linoleic acid, and oleic acid) for protection against gastric mucosal damage elicited by taurocholic acid, acidified aspirin, and ethanol in rats. Each damaging agent induced gastric mucosal lesions in the corpus. Mucosal damage was induced by all agents, and all fatty acids protected the gastric mucosa; however, ethanol and arachidonic acid were the most potent damaging and protecting agents, respectively. Maximally protective doses for prevention of taurocholic acid-induced damage by arachidonic, dihomo-[γ]-linolenic, linoleic, and oleic acids were 50, 200, 100, and 200 mg/kg, respectively; however, 10 mg/kg arachidonic acid reduced lesion length by >50%, whereas minimally effective doses of the other fatty acids were ≥50 mg/kg. Similar potency differences were observed for fatty acid protection against acidified aspirin-induced gastric damage. Although all the fatty acids reduced macroscopic damage, histologic studies showed they did not totally eliminate surface mucosal damage. Microscopic analysis showed that treatment with dihomo-[γ]-linolenic acid or oleic acid attenuated depletion of neutral and acidic glycoproteins from the mucus neck cells of the gastric mucosa in response to exposure to taurocholic acid. Despite having similar gastroprotective activity, arachidonic, dihomo-[γ]-linolenic, linoleic, and oleic acids had very dissimilar abilities to elevate gastric mucosal E-series prostaglandins. Both arachidonic and dihomo-[γ]-linolenic acids elevated E-series prostaglandins, but arachidonic acid had 2–5-fold greater gastroprotective potency. Furthermore, oleic and linoleic acids, which had protective potency similar to that dihomo-[γ]-linolenic acid, did not significantly elevate prostaglandins. These studies failed to demonstrate an absolute correlation between prostaglandin elevation and gastroprotection. The results of this investigation suggest that prostaglandin elevation, although associated with gastroprotection, does not appear to be the sole mechanism for fatty acid-mediated protection of rat gastric mucosa.


Author(s):  
Bernita Br Silaban

Background: "Siasia" is a seaworm species in the phylum that includes Sipuncula Sipunculidea class. This animal has been consumed for generations by coastal communities Nusalaut Island, central mollucas but not yet universally known. Until now there has been obtained gisi complete composition. This study aimed to identify the composition of fatty acids contained in vain fresh seaworms. Method: Seaworms vain taken from coastal waters of Negeri Titawaai and Nalahia Nusalaut Island, Central Moluccas in March 2014. The parameters analyzed include methods is sokhlet fat content and fatty acid by GC method. Result: The results showed fresh siasia fat content 1.12% of coastal waters Titawaai while 1.91% of coastal waters Nalahia. Fatty acids seaworms were identified from coastal waters Titawai  is  kaparat acid (C10: 0), lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1), stearic acid (C18 : 0), linolenic acid (C18: 3) acid and eicosapentaenoic (C20: 5) while the fatty acids of  seaworm vain of coastal waters Nalahia include is lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid ( C16: 1), stearic acid (C18: 0) and eicosapentaenoic acid (C20: 3). Conclusion: Siasia fatty acid from Titawai waters of the identified seven seas of each capsic acid (C10: 0), lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1) , Stearic acid (C18: 0), linolenic acid (C18: 3) and eicosapentaenoic acid (C20: 5) whereas Siasia fatty acids from Nalahia's coastal waters were identified as five lauric acid (C12: 0), myristic acid (C14: 0), palmitoleic acid (C16: 1), stearic acid (C18: 0) and eicosapentaenoic acid (C20: 3).


2003 ◽  
Vol 46 (3) ◽  
pp. 273-276
Author(s):  
S. Müller ◽  
W. Reichardt ◽  
H. Hartung ◽  
B. Eckert

Abstract. Title of the paper: Analysis of the fatty acid composition of the raw fat from the feed of pigs which are examined to her performance (short communication) The raw fat of 14 examining feeds from 13 German performance testing centres for pigs was extracted 2001 and analysed for the fatty acid composition by means of gas chromatography. Besides a great variation of the raw fat content (s % = 42) was to state that with 14.4 g/kg feed on average the content of polyunsaturated fatty acids (PUFA) was high. Examinations of the raw fat of wheat, rye and barley showed that the high proportions in linoleic and linolenic acid are brought in the fattening rations primarily by the cereal components. A limitation of the PUFA proportions below 15 g/kg feed therefore doesn't seem to be practicable in the examining feed of performance testing centres for pigs. The additional variation in the fatty acid composition of examining feeds caused by added fats or oils should however be limited according to a better standardization.


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