scholarly journals THE IMPACT OF OVERWEIGHT AND OBESITY ON THE QUALITY OF LIFE IN CHILDREN WITH BRONCHIAL ASTHMA

2020 ◽  
Vol 73 (6) ◽  
pp. 1140-1144
Author(s):  
Anna V. Kupkina ◽  
Oleksandr P. Volosovets ◽  
Sergii P. Kryvopustov ◽  
Marija P. Prokhorova ◽  
Olena V. Mozyrska

The aim is to investigate if the overweight (OW) and obesity (OB) impact on the quality of life (QOL) of children with bronchial asthma (BA). Materials and methods: The study included 73 children aged 7 – 17, with moderate BA. Depending on the body mass index, patients were divided into the three clinical groups: normal body weight (NW) – 30 children, OW – 28 children and OB – 15 children. QOL was conducted by the Pediatric Asthma Quality of Life Questionnaire (PAQLQ). The statistical processing was carried out using the IBM SPSS Statistics Base (version 22) and EZR version 1.32. Results were considered statistically significant when p<0.05. Results: Children with BA and OB had statistically lower QOL than children with BA and NW in all PAQLQ domains. The Kruskal-Wallis H-test revealed a statistically significant difference between the different weight groups of children with BA both for the general QOL: H(2) = 37.51, p<0.001and for each rating scale separately. Pairwise comparisons using Steel-Dwass test indicated that scores of NW were observed to be significantly different from those of OW and OB for rating Activity and Symptoms scales (p<0.001). Conclusion: Comorbid OW and OB reduce the specific QOL of children with BA. In assessing the effectiveness of specific approaches to treating BA in children with OW and OB, an assessment of the QOL of children should be added to the traditional common clinical and laboratory assessment.

2005 ◽  
Vol 23 (28) ◽  
pp. 6931-6940 ◽  
Author(s):  
Timothy J. Whelan ◽  
Paul E. Goss ◽  
James N. Ingle ◽  
Joseph L. Pater ◽  
Dongsheng Tu ◽  
...  

Purpose To evaluate the impact of letrozole compared with placebo after adjuvant tamoxifen on quality of life (QOL) in the MA.17 trial. Methods Patients completed the Short Form 36-item Health Survey (SF-36) and the Menopause Specific Quality of Life Questionnaire (MENQOL) at baseline, 6 months, and annually. Mean change scores from baseline were compared between groups for summary measures and domains. A response analysis compared the proportion of patients who demonstrated an important change in QOL. Results Of 5,187 randomly assigned women in the trial, 3,612 (69.9%) participated in the QOL substudy: 1,799 were allocated to placebo and 1,813 were allocated to letrozole. No differences were seen between groups in mean change scores from baseline for the SF-36 physical and mental component summary scores at 6, 12, 24, and 36 months. Small (< 0.2 standard deviations) but statistically significant differences in mean change scores from baseline were seen for the SF-36 domains of physical functioning (12 months), bodily pain (6 months) and vitality (6 and 12 months), and the MENQOL vasomotor (6, 12, and 24 months) and sexual domains (12 and 24 months). On the response analysis, a significant difference was seen between groups for the bodily pain domain (percentage of patients reporting a worsening of QOL, 47% placebo v 51% letrozole; P = .009) and the vasomotor domain (22% placebo v 29% letrozole; P = .001). Conclusion Letrozole did not have an adverse impact on overall QOL. Small effects were seen in some domains consistent with a minority of patients experiencing changes in QOL compatible with a reduction in estrogen synthesis.


2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Eisha Gohil ◽  
Ruby Charak, PhD ◽  
Haroon Rashid ◽  
Priyanka Sharma, PhD

Diabetes is a progressive chronic condition which places a significant burden of self management on the individual, such as daily monitoring and medications management, worry about the future and distress about the impact of diabetes on various aspects of life. It is a group of metabolic diseases characterized by elevated blood glucose levels (hyperglycemia) resulting from defects in insulin secretion, insulin action or both. The present study aimed to assess gender differences in quality of life and depression in patients suffering from type I diabetes. A sample of 70 participants (44 male and 26 female) in the age range of 40-80 years was collected from Jammu region, India. WHO Quality of life questionnaire and Beck’s Depression inventory-II were used as tools. Results indicated a significant difference on physical and psychological dimensions of quality of life and on depression across gender. The mean scores indicated that female participants had increased level of depression compared to the male participants. No significant difference was found between male and female on social and environmental dimensions of quality of life.


2012 ◽  
Vol 70 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Paula Luciana Scalzo ◽  
Carolina Reis Flores ◽  
Juliana Rúbia Marques ◽  
Simone Cristina de Oliveira Robini ◽  
Antônio Lúcio Teixeira

Parkinson's disease (PD) is characterized by motor symptoms that cause the decline of functional capacity and affect the quality of life (QoL). Objective: To evaluate the impact of changes in balance and walking capacity on the PD. Methods: The instruments used were: Unified Parkinson's Disease Rating Scale (UPDRS), modified Hoehn and Yahr Scale (HY), Schwab and England scale (SE), quality of life questionnaire (PDQ-39), Berg balance Scale (BBS) and six-minute walk test (6MWT). Results: Thirty-six patients with mean disease duration of 7.3 years were assessed. Lower scores on the BBS and shorter distances walked during the 6MWT correlated with a poorer perception of QoL. This correlation occurred at the expense of the mobility and daily living activities domains. Conclusion: Our results indicated that the impairment in balance while performing functional activities and the reduction in walking capacity are important factors that negatively affect the perception of QoL in PD patients.


2020 ◽  
Vol 6 (1) ◽  
pp. 5-9
Author(s):  
Marcus Vinicius Jardini Barbosa ◽  
◽  
Carolline Gabrielle Campos De Souza ◽  
Cecília Barbosa Oliveira ◽  
Heloísa Loureiro Costa ◽  
...  

Background: Mastectomy is the main method of treating breast cancer and carries a mutilating stigma. Breast reconstruction restores body aesthetics, influencing psychosocial aspects and quality of life. Thus, the aim of the study was to analyze interpersonal and emotional relationships after immediate breast reconstruction. Methods: A qualitative, descriptive and prospective study, was performed through the application of a quality life questionnaire – Breast Evaluation Questionnaire (BEQ 55) in patients who had immediate breast reconstruction, between 2010 to 2019. Results: From the 89 (n=89) women registered in the clinic’s database during the study period, 15 (n=15) of them agreed to participate. The average age was 46 years. Physical domain showed high scores, regarding intimate and sexual activities, professional and work activities, as well as social and recreation activities. Patient’s comfort in front of men were progressive smaller regarding the body dressed, in a swimsuit and naked. The same pattern was observed intimate women and with health professionals. Considering sexual domain scores showed that the more covered, the greater the satisfaction, with an improvement regarding the breasts (73.3%) when compared to the whole body (60.0%). The same pattern was observed regarding the patients’ comfort when being alone, revealing an improvement in the valorization of the breasts in relation to the whole body in the sense of self-image. Conclusion: This study allowed a better understanding of the impact of immediate breast reconstruction showing that this experience can be less traumatic and gradually overcome if there is support from family and health professionals.


2020 ◽  
pp. 096452842096884
Author(s):  
Shan Chen ◽  
Siyou Wang ◽  
Lihua Xuan ◽  
Fu Xu ◽  
Hanti Lu ◽  
...  

Objective: To examine the impact of electroacupuncture (EA) at the ‘four sacral points’ on urge urinary incontinence (UUI). Methods: Twenty-five patients diagnosed with UUI or urgency-predominant mixed urinary incontinence (MUI) were treated by EA at the ‘four sacral points’. EA was performed in the sacrococcygeal region using disposable sterile 0.40-mm-diameter acupuncture needles that were either 100 or 125 mm in length. Treatments were delivered once every other day. Before and after treatment, a questionnaire measuring symptom severity and quality of life associated with UUI was administered. Results: The median total score (interquartile range) from the severity of symptoms and the quality of life questionnaire (Q-score) of the participants was significantly reduced from 12 (7.5, 15) before treatment to 3 (0, 6) after 6 (6, 12) EA treatments. The Q-score of urgency-predominant MUI and UUI was 8 (5, 14.5) and 12.5 (11, 15), respectively, before treatment; after treatment these were reduced to 2 (0, 7.5) and 4.5 (2, 6), respectively. There was no statistically significant difference in the Q-score between urgency-predominant MUI and UUI before and after treatment. Upon treatment completion, seven patients (28%) were ‘cured’ (improvement rate 100%). Treatments were considered ‘markedly effective’ (improvement rate 75% to <100%) in four patients (16%), ‘effective’ (improvement rate 50% to <75%) in eight patients (32%), ‘minimally effective’ (improvement rate 25% to <50%) in three patients (12%), and ‘ineffective’ (improvement rate <25%) in three patients (12%). The overall success rate (comprising ‘cured’, ‘markedly effective’ and ‘effective’ categories) was 76%, and no adverse effects associated with acupuncture treatment were reported. Conclusion: EA at the ‘four sacral points’ was associated with statistically significant improvements in UUI.


2017 ◽  
Vol 07 (03) ◽  
pp. 025-029
Author(s):  
Samrika Bareh ◽  
Fatima D'silva

Abstract Background: Cancer is one of the ten leading cause of death in India. Cancer patients usually present with moderate to severe pain which results usually from the cancer itself or from their treatment .To counteract pain complementary therapies are used along with the medical treatment. The most common used in the clinical setting is Music therapy; which is found to have a positive effect on the physical and psychological response of the patients. Objectives: To find the effectiveness of Music therapy on Pain and Quality of life among Cancer survivors. Material and Method : A quasi experimental research design was adopted for the study. The data were collected using demographic proforma, Numerical Pain rating scale and McGill Quality of life Questionnaire. 50 subjects with moderate to severe pain were identified and were randomly allocated into experimental (25) and control group (25). Experimental groups (25) received Music therapy for 15-20 mins twice a day for a period of 5 days. The control group (25) received no intervention. Pain was assessed twice a day, before and after the intervention for 5 th th days and QoL was assessed on the 6th and 10th day for both the groups.. Results: Majority of the subjects19 (38%) were between the age groups of 41-50 years and most of them 29 (58%) were males. Among the females the most common cancer was breast 12 (24%) and among males it was lungs 10 (20%). Most of the subjects 23(46%) had stage –II cancer, and 28(56%) were on radiation therapy. With regard to treatment, majority 29(58%) were on treatment for a duration of 1-3 months. The study also revealed a significant difference in the level of pain after the music intervention (p<0.05) and a significant improvement in the Quality of life especially affecting the physical and psychological domain (p<0.05). No significant association was found between pain, QoL and selected demographic variables (p<0.05) Conclusion: Music therapy was found to be an effective complementary therapy in reducing the level of pain and improving the QoL of the cancer survivors.


2021 ◽  
Author(s):  
Elena Lysogorskaia ◽  
Timur Ivanov ◽  
Elena Ulmasbaeva ◽  
Aynagul Mendalieva ◽  
Maxim Youshko ◽  
...  

Abstract Background. Yoga originated in the territory of modern India more than 3000 years ago and uses techniques for working with the musculoskeletal system, cardiorespiratory system and attention. Currently, the effectiveness and safety of yoga in patients with various neurological disorders, including MS, is of interest to many scientists and clinicians. The main aim of this study is to examine the effect of yoga on symptoms and quality of life in patients with MS versus physical therapy (exercise therapy) and no exercise.Methods. The patients were randomly assigned to 3 groups (yoga, PT, or waiting list), patients from the waiting list had an opportunity to enter the yoga program after the end of the trial period. After 12 weeks of regular exercises (or absence of them), the effect of yoga and PT on the functional status and quality of life of patients were evaluated. The MS treatment was a part of routine practice, as prescribed by the treating neurologist. The data was collected during the patients’ two visits to the study center - before the start of the study and at the end of the 12-week period. The in-person examination included a doctor's assessment of the EDSS, the SF-36 quality of life questionnaire, the fatigue scale, the Berg balance scale, the 6-minute walking test.Results. A total of 36 patients finished the clinical study: 30 women and 6 men. There was no statistically significant difference between the groups in terms of improvement in MS symptoms as measured by the balance, walking test and fatigue scales. However, in the analysis of the 8 criteria of SF-36 quality-of-life questionnaire the covariation analysis statistically significant differences were found in favor of the yoga group in terms of physical functioning (PF) (p=0.003), life activity (VT) (p<0.001), mental health (MH) (p=013), social functioning (SF) (p=0.028). Conclusions. Thus, regular yoga classes under the guidance of qualified staff are a promising method of non-drug rehabilitation of patients with MS with motor disorders. More research is needed to examine the impact of yoga on clinical patient improvement and quality of life indicators.Trial registration. ISRCTN15486200 https://doi.org/10.1186/ISRCTN15486200


Author(s):  
Elena A. Beigel ◽  
Natalya G. Kuptsova ◽  
Elena V. Katamanova ◽  
Oksana V. Ushakova ◽  
Oleg L. Lakhman

Introduction. Occupational chronic obstructive pulmonary disease (COPD) is one of the leading nosological forms of occupational respiratory disease. Numerous studies have shown high effectiveness of the combination of indacaterol/glycopyrronium (Ultibro®breezhaler®) on the impact on clinical and functional indicators in the treatment of COPD in General practice.The aim of the investigation the case of occupational COPD with the analysis of the dynamics of functional indicators, tolerance to physical load and evaluation of the quality of life of workers engaged in aluminum production by using combination of indacaterol/glycopyrronium.Materials and methods. The random sampling method included 20 men, workers of aluminum production, with the established diagnosis of professional COPD at the age of 40 to 60 years. The survey was conducted (Borg scale, medical Research Council scale (mMRC) and COPD Assessment Test (CAT). Functional methods of studies were conducted: spirometry, body plethysmography, electrocardiography (ECG) and the six-minute stepper test (6-MST).Results. Against the background of 8 weeks of therapy, the volume of forced exhalation for 1 minute (FEV1) increased by 14.7% and amounted to 67.90% of the due values, the forced vital capacity of the lungs (FVC) increased by 11.3% and amounted to 76.95% of the due. According to the body plethysmography (BPG) is set to decrease in residual lung volume on average by 13.4% and static hyperinflation, confirmed by the decrease in functional residual volume (FRV) of 18.8%. During the study period increased physical activity of patients. The average difference between the distance traveled in the six-minute step test before and after treatment was 58.8 m. The analysis of personal data showed that the quality of life of patients improved, the total score in the questionnaire CAT at the beginning of the study was 16.9 points, and after 8 weeks decreased by 63% and amounted to 10.7 points.Conclusions: The Results indicate a positive effect of combination therapy with indacaterol/glycopyrronium on the course and progression of occupational COPD.


Author(s):  
L.S. Priyanka ◽  
Lakshmi Nidhi Rao ◽  
Aditya Shetty ◽  
Mithra N. Hegde ◽  
Chitharanjan Shetty

Abstract Introduction The outcomes of oral health conditions and therapy for those conditions are described by the term “oral health-related quality of life.” Oral health-related quality of life is recognized by the World Health Organization as an important part of the Global Oral Health Program. The study aims to compare the impact of three root canal preparation systems on patients’ quality of life and correlate postoperative pain with the impact on the quality of life. Materials and Methods A survey was performed in which 90 patients were randomly assigned to three groups based on the root canal preparation system: (1) ProTaper Gold (Dentsply, Tulsa Dental Specialties, Tulsa, Oklahoma, United States), (2) Neoendo flex (Neoendo, India),and (3) Hyflex EDM/CM (Coltene Whaledent) that included 30 participants in each group. Data collection included the implementation of a demographic data questionnaire, Oral Health Impact Profile 14 (quality of life), and visual analogue scale(pain). The questionnaire was given after root canal treatment in the first 24 hours. The data obtained were statistically analyzed. Results No significant differences were found in the quality of life among study groups. Group 1 demonstrated a highly significant difference in the postoperative pain with p value of 2.67. Conclusion Within the limitations of the present study, Protaper Gold showed a highly significant difference in postoperative pain when compared with other file systems. No significant differences were found in the quality of life among the study groups.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Åsa Kettis ◽  
Hanna Fagerlind ◽  
Jan-Erik Frödin ◽  
Bengt Glimelius ◽  
Lena Ring

Abstract Background Effective patient-physician communication can improve patient understanding, agreement on treatment and adherence. This may, in turn, impact on clinical outcomes and patient quality of life (QoL). One way to improve communication is by using patient-reported outcome measures (PROMs). Heretofore, studies of the impact of using PROMs in clinical practice have mostly evaluated the use of standardized PROMs. However, there is reason to believe that individualized instruments may be more appropriate for this purpose. The aim of this study is to compare the effectiveness of the standardized QoL-instrument, the European Organization for Research and Treatment of Cancer Quality of Life C-30 (EORTC-QOL-C30) and the individualized QoL instrument, the Schedule for the Evaluation of Individual Quality of Life-Direct Weighting (SEIQoL-DW), in clinical practice. Methods In a prospective, open-label, controlled intervention study at two hospital out-patient clinics, 390 patients with gastrointestinal cancer were randomly assigned either to complete the EORTC-QOL-C30 or the SEIQoL-DW immediately before the consultation, with their responses being shared with their physician. This was repeated in 3–5 consultations over a period of 4–6 months. The primary outcome measure was patients’ health-related QoL, as measured by FACIT-G. Patients’ satisfaction with the consultation and survival were secondary outcomes. Results There was no significant difference between the groups with regard to study outcomes. Neither intervention instrument resulted in any significant changes in health-related QoL, or in any of the secondary outcomes, over time. This may reflect either a genuine lack of effect or sub-optimization of the intervention. Since there was no comparison to standard care an effect in terms of lack of deterioration over time cannot be excluded. Conclusions Future studies should focus on the implementation process, including the training of physicians to use the instruments and their motivation for doing so. The effects of situational use of standardized or individualized instruments should also be explored. The effectiveness of the different approaches may depend on contextual factors including physician and patient preferences.


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