scholarly journals AWARENESS OF FOLIC ACID USE AND ITS EFFECTS AMONG MEDICAL STUDENTS IN UKRAINE

2021 ◽  
Vol 74 (9) ◽  
pp. 2033-2038
Author(s):  
Kateryna Hlushko ◽  
Oksana Boyarchuk ◽  
Maria Kinash ◽  
Emillia Burbela ◽  
Yana Rohalska ◽  
...  
Keyword(s):  
Folic Acid ◽  
Medical Students ◽  
Folic Acid Supplementation ◽  
Folic Acid Deficiency ◽  
General Knowledge ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Acid Deficiency ◽  
The One ◽  
High Level

The aim: To evaluate the awareness of folic acid, its use and effects, general knowledge about neural tube defects among medical students in Ukraine. Materials and methods: This cross-sectional survey was conducted by questioning 114 fourth and fifth years’ students of the Faculty of Medicine. The questionnaire contained questions about folic acid, its dietary sources, effects and periconceptional uses; spina bifida and its main symptoms. Results: Overall, 96.5% of students knew that folic acid was a vitamin and 95.6% were aware of the one natural product which had a high folate level. However, awareness of its amount in different products was insufficient. Overall, 86.8% of surveyed knew that folic acid deficiency during pregnancy caused the congenital malformations. The knowledge of the synthetic folic acid supplementation before and during pregnancy was low (67.5% and 53.5% respectively). Only 10 % of women among medical students consumed folic acid regularly. Conclusions: Despite the high level of general knowledge about folic acid and its effects among medical students in Ukraine, there is a poor awareness of the pre-conception administration of folic acid, and the number of people who regularly take folic acid among the respondents was very low.

scholarly journals The Knowledge Relationship between Mothers who have Children Aged 2-5 years about Anemia toward Stunting Incidence

2021 ◽  
Vol 11 (4) ◽  
pp. 170-179
Author(s):  
Vidi Posdo Simarmata ◽  
Wiradi Suryanegara
Keyword(s):  
Folic Acid ◽  
Red Blood Cells ◽  
Blood Cells ◽  
P Value ◽  
Folic Acid Deficiency ◽  
Cross Sectional ◽  
Study Results ◽  
Acid Deficiency ◽  
Analytical Research ◽  
Iron And Folic Acid

Anaemia is a condition in which there is a decrease in red blood cells or haemoglobin levels in red blood cells caused by several factors such as chronic diseases, iron and folic acid deficiency, or chronic bleeding. Anaemia is one of the world’s nutritional problems, especially in developing countries, including Indonesia. According to RISKESDAS 2013, the number of stunting children in Indonesia had reached 37% (estimated 9 million toddlers) One of the factors that can cause stunting is anaemia during pregnancy. This research aims to determine whether there is a correlation between anaemia-related knowledge of mothers who have children aged 2-5 years old with the incidence of stunting. The research used in the study used analytical research with a cross-sectional method. The data was collected using questionnaires distributed to mothers who have children at the age of 2-5 years in Mekarbakti Village, Sumedang District, West Java. The study results showed that the incidence of stunting is higher in the group of respondents who have better knowledge of anaemia. The conclusion is that there is no correlation between the level of anaemia-related knowledge of mothers who have children aged 2-5 years with the incidence of stunting in Mekarbakti Village (P Value> 0.05). Keywords: Anemia, Stunting, Toddler

scholarly journals A Mixed-Method Study to Determine the Benefits of Periconceptional Folic Acid Supplementation and Effects of Folic Acid Deficiency in Mothers on Birth Outcomes

2016 ◽  
Vol 5 (2) ◽  
pp. e129 ◽  
Author(s):  
Gudlavalleti Venkata S Murthy ◽  
Sunanda Reddy Kolli ◽  
Sutapa B Neogi ◽  
Samiksha Singh ◽  
Komal Preet Allagh ◽  
...  
Keyword(s):  
Folic Acid ◽  
Birth Outcomes ◽  
Mixed Method ◽  
Folic Acid Supplementation ◽  
Mixed Method Study ◽  
Folic Acid Deficiency ◽  
Acid Supplementation ◽  
Acid Deficiency

scholarly journals Study of perceived stress and stressors among undergraduate medical students

2019 ◽  
Vol 6 (4) ◽  
pp. 1690 ◽  
Author(s):  
Renu Sethia ◽  
Gaurav Sharma ◽  
Kirti Shekhawat ◽  
Aarti Aacharya ◽  
Rekha Acharya ◽  
...  
Keyword(s):  
Medical Students ◽  
Perceived Stress ◽  
Medical Training ◽  
Undergraduate Medical Students ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Social Stressors ◽  
Item List ◽  
Medical Undergraduates ◽  
High Level

Background: Recently there is growing concern about stress during undergraduate’s medical training. Undue stress may cause adverse health consequences and lowered academic performance. Objective of the study was to know perceived level of stress and its causes among undergraduate medical students.Methods: A cross sectional survey, using self-structured questionnaire, was conducted among 65 third year medical students. Questionnaires were related to socio-demographic profile, perceived stress scale [PSS] and 32 item list of stressors (grouped as health related, academic and psycho-social). Student’s responses were recorded on five point Likert scale.Results: Mean PSS score was 25.53±5.55 and was significantly higher for females. Psycho-social stressors occurred most frequently, followed by the academic causes.Conclusions: Medical undergraduates face high level of stress and the causes may be varied. They need more interaction, counselling and support from faculty to relieve their stress.

Maternal folic acid supplementation and more prominent birth weight gain in twin birth compared with singleton birth: a cross-sectional study in northwest China

2020 ◽  
Vol 23 (16) ◽  
pp. 2973-2982 ◽  
Author(s):  
Binyan Zhang ◽  
Suhang Shang ◽  
Shanshan Li ◽  
Baibing Mi ◽  
Minmin Li ◽  
...  
Keyword(s):  
Folic Acid ◽  
Birth Weight ◽  
Northwest China ◽  
Population Based ◽  
Folic Acid Supplementation ◽  
Cross Sectional Study ◽  
Shaanxi Province ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Live Births

AbstractObjective:To investigate the association of folic acid (FA) supplementation with birth weight, the risk of small for gestational age (SGA) and low birth weight (LBW) in singleton and twin pregnancy.Design:A population-based cross-sectional survey.Setting:Twenty counties and ten districts in Shaanxi Province of northwestern China, 2013.Participants:28 174 pregnant women with their infants, covering 27 818 single live births and 356 twin live births.Results:The prevalence of FA supplementation in singletons and twins was 63·9 and 66·3 %. The mean birth weight was 3267 (sd 459·1) g, 2525 (sd 534·0) g and 2494 (sd 539·5) g; the prevalence of SGA was 14·3, 51·4 and 53·4 %; the prevalence of LBW was 3·4, 42·4 and 46·6 % among singleton, twin A and twin B, respectively. Compared with non-users, women with FA supplementation were (β 17·3, 95 % CI 6·1, 28·4; β 166·3, 95 % CI 69·1, 263·5) associated with increased birth weight, lower risk of SGA (OR 0·85, 95 % CI 0·80, 0·92; OR 0·45, 95 % CI 0·30, 0·68) and LBW (OR 0·82, 95 % CI 0·71, 0·95; OR 0·50, 95 % CI 0·33, 0·75) in singletons and twins, and more prominent effects in twins. Moreover, there were significant interactions between FA supplementation and plurality on birth weight, SGA and LBW.Conclusions:The present study suggests the association of periconceptional 0·4 mg/d FA supplementation with increased birth weight and reduced risk of SGA and LBW in both singletons and twins, and this association may be more prominent in twins.

scholarly journals Prevalence of Folic Acid And Vitamin B12 Deficiency in Anemic Adolescents

2020 ◽  
Vol 11 (3) ◽  
pp. 4630-4635
Author(s):  
Mayank Jain ◽  
Girish Ganesh Joag ◽  
Kshirsagar V Y
Keyword(s):  
Folic Acid ◽  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Health Concern ◽  
Folic Acid Deficiency ◽  
Cross Sectional ◽  
Female Ratio ◽  
Deficiency Anaemia ◽  
Acid Deficiency ◽  
B12 Deficiency

Adolescents may enjoy nourishment trends, macrobiotic weight control plans and semi-starvation regimens in calories, nutrients and minerals. Protein need in a juvenile for every unit body weight is higher than that of grown-up; however, not exactly a quickly developing newborn child. Adolescence has higher nutrient and mineral needs contrasted and individuals all things considered other life stages. A community-based cross-sectional study of 200 school going anaemic adolescents of age group 10 – 19 years. A predesigned semi-organized survey was readied dependent on the audit of writing on Adolescent iron deficiency. The study included 200 anaemic adolescents belonging to two schools, 89 were males, and 111 were females. Male: female ratio was 1.25:1. Among a total of 200 participants, 122 anaemic adolescents belonged to early adolescence. The mean age of anaemic adolescent participants of this study was 13.19 years with a standard deviation of 1.23. among the participants, 137 anaemic adolescents took a vegetarian diet, and 63 anaemic adolescents took a mixed diet. There were three participants underweight according to BMI classification, and 190 had normal range of BMI, 132 adolescents had moderate anaemia (Hb- 8.0 to 10.9 ). Majority of 66.5%(133/200) had Vitamin B12 deficiency anaemia, 72.5%(145/200) had folic acid deficiency anaemia, and 58.5% (117/200) had combined Vitamin B12 and folic acid deficiency anaemia. Prevalence of anaemia in adolescent is a significant public health concern. Supplementation with not only iron and folic acid but also Vitamin B12 may be need of the day. Besides supplementation adequate education regarding quality food, cooking practices and health education is also necessary to be emphasized in adolescents.

scholarly journals The acceptability of weekly iron-folic acid supplementation and its influencing factors among adolescent school girls in Yogyakarta city: a mix-methods study

2021 ◽  
Vol 27 (1) ◽  
pp. 053-066
Author(s):  
Muhammad Ridwan Ansari ◽  
◽  
BJ Istiti Kandarina ◽  
Nuraini Kusmayanti ◽  
Destriani Destriani ◽  
...  
Keyword(s):  
Folic Acid ◽  
Influencing Factors ◽  
Folic Acid Supplementation ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Acid Supplementation ◽  
Iron Deficient ◽  
School Girls ◽  
Iron Folic Acid Supplementation ◽  
Iron Folic Acid

Introduction: Indonesia has initiated the weekly iron-folic acid supplementation programme (WIFS) among adolescent school girls since 2016. However, its acceptability needs to be investigated. This study aimed to assess the acceptability of WIFS and its influencing factors. Methods: A mixed-methods study was conducted in six schools in Yogyakarta from January-April 2018. Totally, 211 participants aged 12-18 years were involved in the cross-sectional survey, followed by four focus group discussions (FGDs) and in-depth interviews (IDIs). Body mass index-for-age, haemoglobin, serum ferritin, habitual intake, and acceptability (defined as selfreported iron-folic acid tablet consumption) were assessed. Results: This study reported that 22.3% and 12.4% of the participants were categorised as iron deficient and anaemic, respectively. Almost 90% of participants had received the tablet, but only 62.0% of them reported consuming it. Logistic regression test indicated that the participants were more likely to take the tablet if it tasted good [OR (95%CI): 4.66 (1.90-11.43)]. Meanwhile, motivation for tablet consumption declined when respondents perceived the odour of tablet was unpleasant, reported forgetfulness, lacked peer support, and experienced side effects, with OR (95%CI) of 0.23 (0.07- 0.77), 0.35 (0.13-0.95), 0.30 (0.08-0.58), and 0.04 (0.04-0.39), respectively. The results from FGD and IDIs strengthened the findings that the experience of nausea, organoleptic properties of iron-folic acid tablet, forgetfulness, and mother’s support play important roles in students’ acceptability. Conclusion: This study found moderate acceptability towards the WIFS programme. The inhibiting and reinforcing factors of WIFS acceptability in this study could be considered as inputs for programme improvements in the future.

scholarly journals Folates: Key Nutrients to Remember

2017 ◽  
Vol 9 (2) ◽  
pp. 75
Author(s):  
Gourchala Freha ◽  
Mihoub Fatma ◽  
Henchiri Cherifa
Keyword(s):  
Folic Acid ◽  
Macrocytic Anemia ◽  
Folic Acid Supplementation ◽  
Intestinal Lumen ◽  
Folic Acid Deficiency ◽  
Hydrogen Atoms ◽  
Rapid Multiplication ◽  
Vitamin B9 ◽  
Acid Deficiency ◽  
Pteroylglutamic Acid

Folic acid or vitamin B9 or pteroylglutamic acid, is a relatively simple molecule with two characteristics; firstly, it must be reduced by 2 or 4 hydrogen atoms to be metabolically active which makes it sensitive to oxidation and must be protected by ascorbic acid, secondly it may include in addition to the constituent residues of the molecule, 1-7 glutamate residue at one of its ends. These polyglutamate forms that make up the largest share of food folate, must be deconjugated by a specific enzyme present in the intestinal lumen before being absorbed in the jejunum. It is in the methylated form after passing through the enterocyte it is transported in the blood, excreted in bile and reabsorbed. It must be demethylated to integrate folic cell cycle and methyl transfer, that allows the synthesis of methionine (only possible in the presence of vitamin B12), purine, serine and especially thymidylic acid, constitutive DNA. As a methyl donor that plays a fundamental role in cerebral and nervous metabolism. Folates are involved in cell division thus; any folic acid deficiency causes a slowdown in rapid multiplication systems which may lead to red blood cell disorders (macrocytic anemia), immunity, and neural tube defects, in addition to physiological disorders (cardiovascular, cancer ...). Folic acid supplementation appears to allow the correction of these disorders.

FOLATE METABOLISM AND PREECLAMPSIA

2012 ◽  
Vol 23 (2) ◽  
pp. 131-155 ◽  
Author(s):  
YANFANG GUO ◽  
GRAEME N. SMITH ◽  
SHI WU WEN ◽  
MARK C WALKER
Keyword(s):  
Folic Acid ◽  
Complex Disease ◽  
Folic Acid Supplementation ◽  
Folate Metabolism ◽  
Folic Acid Deficiency ◽  
Multisystem Disorder ◽  
Acid Deficiency ◽  
The Subject ◽  
Underlying Mechanisms ◽  
The Relationship

Preeclampsia (PE) is a multisystem disorder of human pregnancy, affecting about 6% of all pregnancies worldwide, and is one of the leading causes of maternal and infant morbidity and mortality. Despite decades of research into the pathogenesis of this complex disease, the underlying mechanisms remain unclear. As a result, the options for prevention and management of PE are limited. In recent years, there has been a growing body of evidence suggesting that folate deficiency is associated with PE, and folic acid supplementation may reduce the risk of developing PE in certain populations. Folate contributes to cell division and growth, and folate metabolism is involved in a large number of physiological and pathophysiological processes in human development. Sufficient supply of folate is therefore particularly important during pregnancy. Nevertheless, the exact mechanisms of folic acid deficiency increasing the risk of developing PE are still unclear. This article reviews what is understood about the aetiology of PE and the relationship between folate metabolism and PE so as to enhance further discussions on the subject.

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