scholarly journals Transarterial Chemoembolization (TACE) with Lipiodol� in HCC PatientsTechnical, clinical and imagistic aspects

2019 ◽  
Vol 56 (1) ◽  
pp. 194-187
Author(s):  
Decebal Fodor ◽  
Bogdan Andrei Suciu ◽  
Ioan Jung ◽  
Simona Gurzu ◽  
Tamas-Csaba Sipos ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Alternative Therapy ◽  
Life Quality ◽  
Case Series ◽  
Hepatic Tumors ◽  
Hepatic Transplantation ◽  
Therapeutic Attitude ◽  
Control Tumor ◽  
Prolongation Of Life

Hepatocellurar carcinoma (HCC) is the most frequent primary hepatic tumor, the vast majority of patients have less than a 12 month survival rate. The aim of this study was to evaluate the efficacy of TACE in patients with HCC, based on a case series and literature review. The study included 12 consecutive patients with HCC who underwent surgical treatment (resection, liver transplantation � resection) at the Department of Transplantation and Surgery, Semmelweis University, Budapest, during 2009-2015. All the patients received at least one TACE session. Patients with BCLC B-stage who benefit from TACE and another alternative therapy (eg, RFA) may be associated with or exhibit tumor stagnation, or tumor necrosis in most cases. In C BCLC stages, desperate cases - the two patients to whom TACE was the last therapeutic attitude, despite the predicted prognosis, TACE assured the prolongation of life and increased life quality. In the majority of patients in this study, stage A BCLC, chemoembolization was a therapeutic attitude that allowed subsequent liver transplantation (when it was not feasible initially due to tumor size) or liver resection in apparently inoperable cases. The arterial chemotherapy is the unanimously accepted indication in patients with stage B, BCLC. The data presented encourages us to opt for TACE with the intention of destaging BCLC and giving an operability character to the hepatic tumors (resection � hepatic transplantation). In stage C BCLC, TACE can be a last attempt to improve the quality of life and to control tumor progression.

scholarly journals A Comprehensive Review Evaluating the Impact of Protein Source (Vegetarian vs. Meat Based) in Hepatic Encephalopathy

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 370
Author(s):  
Umair Iqbal ◽  
Ravirajsinh N. Jadeja ◽  
Harshit S. Khara ◽  
Sandeep Khurana
Keyword(s):  
Hepatic Encephalopathy ◽  
Protein Intake ◽  
Alternative Therapy ◽  
Case Series ◽  
Current Evidence ◽  
Branch Chain Amino ◽  
The Impact ◽  
Protein Diets

Hepatic encephalopathy (HE) is a common neurological consequence in patients with cirrhosis and has a healthcare burden of USD 5370 to 50,120 per patient annually. HE significantly hampers the quality of life and is a major cause of morbidity and mortality. Patients with cirrhosis are at a high risk for protein-calorie malnutrition due to altered metabolism. Current evidence has changed the old belief of protein restriction in patients with cirrhosis and now 1.2 to 1.5 g/kg/day protein intake is recommended. Case series and studies with small numbers of participants showed that a vegetarian protein diet decreases the symptoms of HE when compared to a meat-based diet, but the evidence is limited and requires further larger randomized controlled trials. However, vegetable or milk-based protein diets are good substitutes for patients averse to meat intake. Branch chain amino acids (BCAA) (leucine, isoleucine and valine) have also been shown to be effective in alleviating symptoms of HE and are recommended as an alternative therapy in patients with cirrhosis for the treatment of HE. In this review, we provide an overview of current literature evaluating the role of protein intake in the management of HE in cirrhosis.

scholarly journals Rehabilitation Challenge of Motor Neuron Disease Following Occupational Exposure to Magnetic Fields and Electric Shocks: Case Series

KYAMC Journal ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 218-221
Author(s):  
Fatema Newaz ◽  
Md Israt Hasan ◽  
Mohammed Emran ◽  
Syed Mozaffar Ahmed ◽  
Jasmine Jashimuddin
Keyword(s):  
Motor Neuron ◽  
Motor Neurons ◽  
Neurodegenerative Disorder ◽  
Life Quality ◽  
Case Series ◽  
Psychological Issue ◽  
Performance Deficits ◽  
Electric Injury ◽  
High Level

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder of motor neurons and their axons characterized by signs of upper and lower motor neuron dysfunction. ALS has been associated with exposures in so called electrical occupation. We have found two young patient who developed features of MND following electrocution within 1 year. Due to this great diversity of possible causing agents for ALS, new researches are necessary to elucidate possible etiologies for a better approach to the patients, promoting preventive programs for the disease, optimizing functions and improving the life quality of the patients. A number of studies have demonstrated cognitive performance deficits following electric injury observed cognitive symptoms and neurobehavioral defecit. As treatment approach rehabilitation is important part of treatment as pharmacological part didn't prove strong recovery. As MND causes high level of disability and dependency on caregiver causes gap in rehabilitation due to psychological issue. Neuropalliative rehabilitation is more important in these patient which is unavailable in our country. KYAMC Journal Vol. 11, No.-4, January 2021, Page 218-221

scholarly journals LUMBAR SPINAL STENOSIS: EVALUATION OF PAIN AND LIFE QUALITY AFTER SURGICAL TREATMENT

2019 ◽  
Vol 18 (1) ◽  
pp. 37-42
Author(s):  
Gustavo Alvarenga ◽  
João Otávio Araújo Rotini ◽  
Leonardo Yukio Jorge Asano ◽  
Vinícius Alves de Andrade ◽  
André Evaristo Marcondes Cesar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Surgical Treatment ◽  
Life Quality ◽  
Case Series ◽  
Level Of Evidence ◽  
The Mean ◽  
One Year ◽  
Lumbar Spinal

ABSTRACT Objective: The objective of this study was to present an analysis of progression of the quality of life and pain in patients undergoing surgical treatment of LSS and the potential correlations between individual factors and the clinical outcome observed. Methods: We studied 111 patients undergoing surgical treatment of LSS from January 2009 to December 2011 using the functional capacity (ODI) and pain (VAS) questionnaires. The preoperative data were compared statistically with the results obtained during the postoperative follow-up at one month, six months, one year, and two years. Results: The population consisted of 60 men and 51 women. The mean age was 61.16 years at the time of surgery, 33.33% were 60 years or older. When the questionnaires were applied, we found improvement in the progressive disability assessment with a mean drop of 23.65 ODI points after 6 months of the surgical treatment and 27.47 at the end of one year of surgery compared to preoperative for this scale. There was a decline of 3.84 points (mean) in the VAS at first postoperative month. Conclusion: Surgical treatment of LSS presented favorable postoperative evolution in a 2-year follow-up regarding pain and quality of life through VAS and ODI. Level of Evidence IV; Case series.

scholarly journals Characteristics of Argininemia and Effect of Liver Transplantation-the Largest Experience in China

2021 ◽  
Author(s):  
Bin Cui ◽  
Lin Wei ◽  
Zhi-Jun Zhu ◽  
Li-Ying Sun ◽  
Wei Qu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Liver Transplantation ◽  
Alternative Therapy ◽  
Poor Response ◽  
Physical Growth ◽  
Morphological Examination ◽  
Arginase 1 ◽  
Number Of Patients ◽  
Coagulation Dysfunction

Abstract Background: Argininemia is a rare urea cycle disorder due to arginase-1 deficiency, characterized by progressive spastic paraplegia. Coagulation dysfunction has been reported in few researches, and the pathophysiology is still unclear. Advances in diagnosis and treatment have increased the number of patients receiving effective management; however, not all symptoms are prevented under traditional treatments, and there is no consensus on liver transplantation (LT) for the treatment of patients with argininemia. Methods: We conducted a retrospective study of patients who had been done LT in our center between January 2015 and November 2019. Eleven patients with argininemia were included for their poor response to protein restriction dietary and alternative therapy of nitrogen scavengers. The details on coagulation, liver function, histopathological and morphological examination of liver samples, and other clinical presentations were extracted. The Grading Scale for evaluating neurological status and classification of physical growth and quality of life was used to assess the effect of LT. Results: All patients demonstrated hyperarginine, progressive neurological impairments, among whom nine patients presented coagulation dysfunction pre-oparation. After LT, the coagulation index and plasma arginine returned to normal in all patients, and neurological symptoms, growth deficit, and quality of life improved significantly without any severe complications. All patients survive to date. Conclusions: Our findings indicated that coagulation abnormality was a typical presentation of argininemia. LT can prevent progressive neurological impairment and restore metabolic disorders entirely.

Life quality of patients undergoing liver transplantation

1994 ◽  
Vol 7 (s1) ◽  
pp. 675-678 ◽  
Author(s):  
P. Ramirez ◽  
F. Sanchez ◽  
R. Robles ◽  
J. Lujan ◽  
P. Rodriguez ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Life Quality

scholarly journals P096 QUALITY OF LIFE FOLLOWING ROBOTIC-ASSISTED RETROMUSCULAR VENTRAL HERNIA REPAIR

2021 ◽  
Vol 108 (Supplement_8) ◽  
Author(s):  
Alexandros Valsamidis ◽  
Mathias Frederichsen ◽  
Kristian Als Nielsen ◽  
Mads Harthimmer ◽  
Per Helligsø ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hernia Repair ◽  
Ventral Hernia ◽  
Ventral Hernia Repair ◽  
Life Quality ◽  
Case Series ◽  
Rank Test ◽  
Safe Procedure ◽  
Robotic Assisted

Abstract Aim Robotic-assisted ventral hernia repair (rVHR) has emerged as an alternative to current open and laparoscopic procedures. The present study aims to determine the effect of rVHR on postoperative quality of life. Material and Methods Patients undergoing elective rVHR from 01/01 2017 until 12/6 2020 were identified from the hospitaĺs electronic medical record system. Patient demographic, clinical presentation, location of the hernial defect and postoperative complications were obtained from the case notes. A phone interview was also conducted to assess postoperative life quality using the EuraHS-QoL questionnaire. The pre and postoperative life quality assessment was performed to determine the effect of robotic-assisted ventral hernia repair on 1. Pain at the site of the hernia, 2. Restrictions of activities due to pain or discomfort at the site of the hernia and 3. Esthetical discomfort. Moreover, patients were asked whether they felt their overall quality of life had improved, deteriorated or was unaltered after the procedure. A Wilcoxon signed rank test was conducted to determine the effect of the repair on postoperative life quality. Results 85 out of 99 patients completed the interview and were included in this case series. The survey revealed a highly significant improvement of life quality in all categories (P < 0. 01). 86% of the participants reported that their overall quality of life had improved, 13% reported no change and 1% felt that it had deteriorated. Conclusions Robotic-assisted retromuscular ventral hernia repair is a safe procedure that is associated with a significant improvement of patient quality of life.

scholarly journals Secukinumab efficacy in the treatment of various types of psoriasis: A case series

2021 ◽  
Vol 0 ◽  
pp. 1-5
Author(s):  
K. Geetha ◽  
N. Sudhakar
Keyword(s):  
Tertiary Care ◽  
Life Quality ◽  
Case Series ◽  
Severity Index ◽  
Rapid Onset ◽  
Onset Of Action ◽  
Psoriasis Area Severity Index ◽  
College Hospital ◽  
Medical College

The aim of this article is to describe our experience in a tertiary care medical college hospital with secukinumab in the treatment of various types of psoriasis as a case series of 10 patients. All the patients showed significant improvement in psoriasis area severity index and dermatology life quality index scores with no major adverse event reported during the period of study for 6 months duration. Secukinumab may be effective and safe for the treatment of all types of psoriasis with rapid onset of action and improvement in the quality of life.

Income and Life Quality of Farmer Households Suffering Social Exclusion

2012 ◽  
pp. 63-87
Author(s):  
Anh Mai Ngoc ◽  
Ha Do Thi Hai ◽  
Huyen Nguyen Thi Ngoc
Keyword(s):  
Labor Market ◽  
Statistical Method ◽  
Social Exclusion ◽  
Central Government ◽  
Life Quality ◽  
Economic Aspect ◽  
Local Authorities ◽  
The Impact

This study uses descriptive statistical method to analyze the income and life qual- ity of 397 farmer households who are suffering social exclusion in an economic aspect out of a total of 725 households surveyed in five Northern provinces of Vietnam in 2010. The farmers’ opinions of the impact of the policies currently prac- ticed by the central government and local authorities to give them access to the labor market are also analyzed in this study to help management officers see how the poli- cies affect the beneficiaries so that they can later make appropriate adjustments.

Quality of life of patients with Sjogren’s disease with ongoing therapy with diseasemodifying antirheumatic drugs

2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Life Quality ◽  
Well Being ◽  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Sf 36 ◽  
Disease Modifying ◽  
Sjögren’S Disease

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.

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