Chemical Ablation of the Tissue in ENT Surgery

2018 ◽  
Vol 69 (1) ◽  
pp. 286-289
Author(s):  
Catalina Pietrosanu ◽  
Viorel Zainea ◽  
Irina Ionita ◽  
Cristian Dragos Stefanescu ◽  
Mura Hainarosie ◽  
...  

Various interventions require tissue ablation in ENT surgery. This can be achieved using a multitude of methods, but the tendency today is to use minimally invasive methods. The development of new technologies has allowed us to consider the use of coblation for tissue ablation, which is based on a chemical reaction, instead of a thermal or mechanical ablation. The technology proved to be extremely used in the field of ENT. Its indications range from functional surgery to benign or even malignant tumors and it can be used in the nose, pharynx and larynx, with probes of different length and angulation. This minimally invasive method of tissue ablation associates less scaring, a faster recovery and a lower postoperative discomfort. Although the time required for the intervention may be somewhat longer, the overall results are superior to the classical methods, considering it provides instant hemosthasis as well. We consider it to be a reliable method, fit for a wide range of indications.

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1662
Author(s):  
Ioana Maria Maier ◽  
Adrian Cornel Maier

Many studies have tried to understand the mechanism of endometriosis and its manner of manifestation. However, the only method of diagnosis considered as the gold standard in endometriosis is an invasive method called exploratory laparoscopy. Hence, there is a need to identify non-invasive or minimally invasive methods to minimize patients’ suffering, thus increasing their addressability at the earliest possible staging of the disease, and to diagnose this condition as soon as possible. miRNAs (microRNAs) and lncRNAs (long-noncoding RNAs) are potential non-invasive diagnostic methods for endometriosis. Multiple clinical trials indicate that miRNA can be used as a non-invasive method in the diagnosis and differentiation of endometriosis stages.


2019 ◽  
Vol 178 (2) ◽  
pp. 69-72
Author(s):  
A. N. Ryazanov ◽  
V. V. Soroka ◽  
S. P. Nokhrin ◽  
E. P. Mikhelson ◽  
I. D. Magamedov ◽  
...  

The article describes the clinical experience of treatment of life-threatening pathology by minimally invasive methods. There is a long-term stable positive result after the operation. The introduction of new technologies in medicine minimizes the risk of postoperative complications, contributing to a favorable outcome of the disease.


2018 ◽  
Vol 22 (4) ◽  
pp. 199-204
Author(s):  
V. V. Gatsutsyn ◽  
A. E. Nalivkin ◽  
V. A. Kuzmichev ◽  
Aleksandr E. Mashkov ◽  
D. A. Pykhteev

Funnel-shaped deformation of the chest (pectus excavalus) is a congenital pathology of the anterior thoracic wall, manifested by the retraction of the sternum and sternocostal cartilages in various forms and degrees. There are many options for correcting this deformation, which can be conditionally divided into open and minimally invasive methods. In the leading clinics for this pathology, there is recently used the most minimally invasive method of correction by Nass. Unfortunately, for today there is no the only as an algorithm for preoperative examination of patients with this pathology, as well as the decision on the choice of surgical correction method.


2018 ◽  
Vol 69 (3) ◽  
pp. 642-644
Author(s):  
Andreea Rusescu ◽  
Catalina Pietrosanu ◽  
Irina Ionita ◽  
Cristian Dragos Stefanescu ◽  
Anca Mihaela Pantea Stoian ◽  
...  

Throughout the years, minimally invasive methods have gained ground when considering the surgical field. Most of all, these techniques are used in tissue ablation as they associate less operative and postoperative bleeding, high rate of recovery, as well as minimal scaring. One of these minimally invasive methods refers to the use of chemical ablation or coblation when regarding tissues ablation, thus using a chemical reaction based technique despite the regular use of mechanical or thermal interactions in order to achieve tissue ablation. Widely used in the area of ENT surgery, coblation could easily be defined as an extremely effective technique in dealing with the submucosal tissue in volumetric reduction of inferior turbinate. Different length and angulation probes ensure the applicability of this technique to better correlate with any anatomical variants and local features of the targeted structures to be ablated. Although the duration of surgery by using this method is slightly higher than with the use of other inferior tubinate volumetric reduction techniques such as radiofrequency or use of the shaver, the low degree of postoperative discomfort and the good local hemostasis provided by this technique are markers that support its elective use if it is available for the surgeon.


1992 ◽  
Vol 38 (9) ◽  
pp. 1596-1600 ◽  
Author(s):  
B H Ginsberg

Abstract Self-measurement of blood glucose is an integral part of diabetes mellitus therapy. As many as 65% of diabetic people (4-5 million people) perform some degree of self-monitoring and approximately 20-30% do so frequently. Most patients consider this the most onerous part of their diabetes therapy. It requires obtaining blood, frequently in public, and is usually the most painful part of therapy, being significantly more painful than insulin self-administration. Patients therefore are anxious for a less-invasive method for glucose measurement. Methods exist or are being developed for minimally invasive glucose monitoring, which use body fluids other than blood (e.g., sweat and saliva), subcutaneous tissue, or blood measured less invasively. Sweat and saliva are relatively easily obtained but their glucose concentration lags significantly behind blood glucose. Methods to increase sweating have been developed and seem to increase the timeliness of the sweat glucose measurement. Subcutaneous glucose measurement seems to lag only a few minutes behind blood glucose and may actually be a better measurement of the critical values of glucose concentrations in brain, muscle, and other tissue. Glucose can be measured by noninvasive or minimally invasive methods, such as those making skin or mucous membranes permeable to glucose or those placing a reporter molecule in the subcutaneous tissue. Needle-type sensors have been improved in accuracy, size, and stability and can be placed into the subcutaneous tissue or peripheral veins to monitor blood glucose with miniature instruments.


2019 ◽  
Vol 178 (4) ◽  
pp. 26-28
Author(s):  
K. M. Kurbonov ◽  
K. R. Nazirboev

The OBJECTIVE of the study was to improve the results of treatment of patients with fluid collections in acute pancreatitis with a minimally invasive method. MATERIAL AND METHODS. Results of percutaneous-puncture interventions under ultrasound in 62 patients with acute pancreatitis in the presence of fluid clusters were analyzed. In the first day from the moment of the disease, 39 % of patients admitted during the second and the third days – 31 % and more than three days – 20 % of patients. RESULTS. Diagnostic punctures of fluid collections under ultrasound control were performed. In 49 (79 %) of 62 patients, the puncture was effectively transformed into percutaneous drainage. In 13 of 49 patients were further operated. Lethal outcomes after puncture-draining interventions were in 5 cases. Among 44 patients operated with a minimally invasive method of acute pancreatitis, recovery was noted in 24, recurrence of fluid collections – in 7, 13 patients were operated on. CONCLUSION. Thus, early diagnosis and timely implementation of conservative and minimally invasive methods of treatment contributed to improving the immediate results of treatment of patients with fluid collections in acute pancreatitis.


Author(s):  
Anthony S-Y Leong ◽  
David W Gove

Microwaves (MW) are electromagnetic waves which are commonly generated at a frequency of 2.45 GHz. When dipolar molecules such as water, the polar side chains of proteins and other molecules with an uneven distribution of electrical charge are exposed to such non-ionizing radiation, they oscillate through 180° at a rate of 2,450 million cycles/s. This rapid kinetic movement results in accelerated chemical reactions and produces instantaneous heat. MWs have recently been applied to a wide range of procedures for light microscopy. MWs generated by domestic ovens have been used as a primary method of tissue fixation, it has been applied to the various stages of tissue processing as well as to a wide variety of staining procedures. This use of MWs has not only resulted in drastic reductions in the time required for tissue fixation, processing and staining, but have also produced better cytologic images in cryostat sections, and more importantly, have resulted in better preservation of cellular antigens.


2012 ◽  
Vol 3 (1) ◽  
pp. 20-22
Author(s):  
Dr. Dhaval J Patel ◽  
◽  
Dr. Bipin B Chhajed ◽  
Dr. Dhaval R Modi ◽  
Dr. Nirav P Trivedi ◽  
...  

Author(s):  
Trần Thanh Nhàn

In order to observe the end of primary consolidation (EOP) of cohesive soils with and without subjecting to cyclic loading, reconstituted specimens of clayey soils at various Atterberg’s limits were used for oedometer test at different loading increments and undrained cyclic shear test followed by drainage with various cyclic shear directions and a wide range of shear strain amplitudes. The pore water pressure and settlement of the soils were measured with time and the time to EOP was then determined by different methods. It is shown from observed results that the time to EOP determined by 3-t method agrees well with the time required for full dissipation of the pore water pressure and being considerably larger than those determined by Log Time method. These observations were then further evaluated in connection with effects of the Atterberg’s limit and the cyclic loading history.


2013 ◽  
Vol 16 (1) ◽  
pp. 59-67

<p>The Soil Science Institute of Thessaloniki produces new digitized Soil Maps that provide a useful electronic database for the spatial representation of the soil variation within a region, based on in situ soil sampling, laboratory analyses, GIS techniques and plant nutrition mathematical models, coupled with the local land cadastre. The novelty of these studies is that local agronomists have immediate access to a wide range of soil information by clicking on a field parcel shown in this digital interface and, therefore, can suggest an appropriate treatment (e.g. liming, manure incorporation, desalination, application of proper type and quantity of fertilizer) depending on the field conditions and cultivated crops. A specific case study is presented in the current work with regards to the construction of the digitized Soil Map of the regional unit of Kastoria. The potential of this map can easily be realized by the fact that the mapping of the physicochemical properties of the soils in this region provided delineation zones for differential fertilization management. An experiment was also conducted using remote sensing techniques for the enhancement of the fertilization advisory software database, which is a component of the digitized map, and the optimization of nitrogen management in agricultural areas.</p>


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