scholarly journals A study on wound healing activity of Bacopa monnieri Linn. aerial parts

2007 ◽  
Vol 7 (2) ◽  
pp. 150-156
Author(s):  
Tirtha Ghosh ◽  
Tapan Kumar Maity ◽  
Deepak Kumar Dash ◽  
Anindya Boss
Keyword(s):  
Wound Healing ◽  
Bacopa Monnieri ◽  
Aerial Parts ◽  
Wound Healing Activity

scholarly journals Wound Healing Activity ofRubus sanctusSchreber (Rosaceae): Preclinical Study in Animal Models

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Ipek Süntar ◽  
Ufuk Koca ◽  
Hikmet Keleş ◽  
Esra Küpeli Akkol
Keyword(s):  
Wound Healing ◽  
Histopathological Examination ◽  
Folk Medicine ◽  
Preclinical Study ◽  
Aerial Parts ◽  
Ointment Formulation ◽  
Infected Insect ◽  
Healing Of Wounds ◽  
Insect Bites ◽  
Wound Healing Activity

Young shoots ofRubusspecies have been used for healing of wounds, infected insect bites and pimples in folk medicine for ages. In order to evaluate the wound healing activity ofRubus sanctus, four different extracts were prepared from the whole aerial parts of the plant by usingn-hexane, chloroform, ethyl acetate and methanol, respectively. Incision wound healing model by using tensiometer on rats and excision model on mice were employed to assess the activity. Remarkable wound healing activity was observed with the ointment formulation of the methanol extract at 1% concentration on the mentioned models. The results of histopathological examination also supported the outcome of both incision and excision wound models. The wound healing effect was comparatively evaluated with a reference ointment Madecassol. The experimental data confirmed the ethnobotanical usage ofR. sanctus.

WOUND HEALING ACTIVITY OF AERIAL PARTS OF EUPHORBIA HIRTA LINN. AND ITS POLYHERBAL FORMULATION

INDIAN DRUGS ◽  
2020 ◽  
Vol 57 (07) ◽  
pp. 58-62
Author(s):  
Pushpendra Kumar Jain ◽  
Yogesh Pounikar ◽  
Navneet Khurana
Keyword(s):  
Wound Healing ◽  
Ethanolic Extract ◽  
Albino Rats ◽  
Euphorbia Hirta ◽  
Polyherbal Formulation ◽  
Aerial Parts ◽  
Tridax Procumbens ◽  
Histopathological Studies ◽  
Wound Healing Activity

This study was undertaken to investigate the in vivo wound healing activity of ethanol extracts of the aerial parts of Euphorbia hirta Linn. and its polyherbal formulation with Tridax procumbens and Eclipta alba. The in vivo wound healing activity was assessed in albino rats by using three wound models i.e. excision wound, incision wound and dead space wound models. Level of biochemical markers and histological changes were monitored to evaluate the enhancement of wound healing. The results showed that ethanolic extract ointment possesses a definite prohealing action. This was demonstrated by a significant increase in the rate of wound contraction and by enhanced epithelization. Significant increase in tensile strength, hydroxyproline content and collagen levels were observed, which was further supported by histopathological studies and gain in granuloma breaking strength.

Wound Healing Activity of Ten Indigenous Plants in Incision and Excision Wound Models in Albino Rats

2012 ◽  
Vol 2 (9) ◽  
pp. 56-58
Author(s):  
Vasanthalaxmi K Vasanthalaxmi K ◽  
◽  
Saraswathi Udupa ◽  
Laximinarayana Udupa
Keyword(s):  
Wound Healing ◽  
Albino Rats ◽  
Indigenous Plants ◽  
Excision Wound ◽  
Wound Healing Activity

Comparison of the ficus for the wound healing activity in various species

2020 ◽  
Vol 10 (4) ◽  
pp. 67-70
Author(s):  
Mothilal K ◽  
Akila CR ◽  
Mahender K ◽  
Chaitanya Kumar K ◽  
Ravi D
Keyword(s):  
Wound Healing ◽  
Wound Closure ◽  
Subcutaneous Tissue ◽  
Significant Activity ◽  
Herbal Extracts ◽  
Standard Drug ◽  
Excision Wound ◽  
Injuries And Wounds ◽  
Skin Conditions ◽  
Wound Healing Activity

Injuries and wounds are any sorts of damage to the skin or subcutaneous tissue. Usually, any wounds of such sorts are self-healed. Sometimes, there may be a delay in healing, and that delay is caused due to the functional delays in various processes of wound healing. All the Ficus plants show similar activities like the antioxidant, anti-inflammatory and wound healing properties 7including skin conditions like ulcers and rheumatism. The anthelmintic property and immunomodulatory are also seen. The herbal extracts of the same family of Ficus in different plants were investigated for the wound healing activity in the excision wound method, and the extracts showed significant activity compared to the drug. All the extracts showed a better healing ability, but the extract of FBO-100 showed the highest activity followed by FMO followed by FHO and finally the FRO. Overall, the activity of the extract ointment was comparable and was significant compared to the standard drug ointment. The wound closure of the extract ointment treated groups were better and were completed in 12 days, and the activity was more than 96%. The herbal extracts of the same family of Ficus in different plants were investigated for the wound healing activity in the excision wound method, and the extracts showed significant activity compared to the drug. The plants of microcarpa, benghalensis, religiosa and hispida are compared for the activity, and the order showed for the activity was FBO>FMO>FHO>FRO.

In Vivo Wound Healing Activity of Spirulina platensis

2019 ◽  
Vol 18 (1) ◽  
pp. 06-16
Author(s):  
R. Seghiri ◽  
A. Essamri
Keyword(s):  
Wound Healing ◽  
Spirulina Platensis ◽  
Therapeutic Agent ◽  
Conventional Medicine ◽  
Folk Medicine ◽  
Chemical Burns ◽  
Amount Of Substance ◽  
Test Population ◽  
Wound Healing Activity

Spirulina is a microalga used in traditional folk medicine in Morocco for the treatment of various health disorders. The wound healing activity of Moroccan Spirulina is unknown. In the current study, aqueous extracts of Spirulina platensis were investigated for acute toxicity and wound healing activity in Swiss Albino mice and White New Zealand rabbits, respectively. The LD50 (amount of substance required to kill 50% of the test population) of the microalga was greater than 5,000 mg/kg. Healing after application of the same amount of ointment on differently induced (mechanical, chemical, and thermal) wounds was about the same, over five weeks. Aqueous extract had remarkable healing activity on rabbits’ skin, possessing significantly greater healing effect for mechanical and chemical burns than controls. Moreover, the hair growing time was faster in treated groups; Spirulina-treated groups did not show any contamination with microbes compared to others. This study affirms that Spirulina platensis can be considered as a potential therapeutic agent for wound healing not only as a complementary medicine but also in conventional medicine.

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