Red Pepper Powder and Kimchi Reduce Body Weight and Blood and Tissue Lipids in Rats Fed a High Fat Diet

Background Rasbora agrotynea (local name : Seluang ) is a fish native to Sumatera, Malaya and Borneo. This fish has a potential as a local wisdom for supplementation of omega 3 and omega 6. In Sumatera, Seluang fish was used as traditional food. Aim of Study Aim of this study to explore the efficacy of seluang fish oil in body weight, lipid profile, adiponectin and leptin level in Wistar Rats-Induced High Fat Diet Methods This study was an experimental study , pre-post test with control group design. The sample in this study was 30 male rats, 8 weeks old, weight 150-200 gram. Rats were given high fat diet and seluang fish oil at dose of 0,1 , 0,2 and 0,4 mL/200 gr BW/day for 2 weeks. Seluang fish oil was extracted by distilation methods. The results of this study were assayed by SPSS 18. Results Seluang fish oil 0,4 mL/200 gr BW was more potent to reduce body weight gain, triglyseride level, leptin and increase adiponectin level than seluang fish oil 0,1 mL/200 gr BW, 0,2 mL/200 gr BW, negative control and positive control. Conclusion Seluang fish oil had a potention to reduce body weight, triglyceride, leptin and increase adiponectin level. Keywords: Seluang fish Oil â€“ body weight- triglyserida â€“ leptin - adiponectin

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B Vitamins Can Reduce Body Weight Gain by Increasing Metabolism-related Enzyme Activities in Rats Fed on a High-Fat Diet

Current Medical Science ◽

10.1007/s11596-018-1862-9 ◽

2018 ◽

Vol 38 (1) ◽

pp. 174-183 ◽

Cited By ~ 1

Author(s):

Ying Zheng ◽

Ai-guo Ma ◽

Ming-ci Zheng ◽

Qiu-zhen Wang ◽

Hui Liang ◽

...

Keyword(s):

Body Weight ◽

Weight Gain ◽

Enzyme Activities ◽

High Fat Diet ◽

Body Weight Gain ◽

B Vitamins ◽

High Fat ◽

Reduce Body Weight ◽

Related Enzyme

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The Efficacy of Lerek Fruits (Phrynium maximum)Extract Related Body Weight, Lipid Profile and Leptin in Wistar Rats-Induced High Fat Diet

BioScientia Medicina ◽

10.32539/bsm.v1i1.10 ◽

2017 ◽

Vol 1 (1) ◽

pp. 8-13

Author(s):

Radiyati Umi Partan ◽

Rachmat Hidayat ◽

Yeni Agustin ◽

Mgs Irsan Saleh ◽

Nita Parisa ◽

...

Keyword(s):

Body Weight ◽

Lipid Profile ◽

High Fat Diet ◽

Wistar Rats ◽

Body Weight Gain ◽

Male Rats ◽

Control Group ◽

High Fat ◽

Fruit Extract ◽

Reduce Body Weight

Background Phrynium maximum (local name : lerek ) is a plant native to Sumatera, Malaya and Borneo. This plants have a potential as a local wisdom for therapeutics. In Sumatera, Lerek was used as traditional treatment for fever, diarrhea, diabetics and for wound healing. Aim of Study Aim of this study to explore the efficacy of lerek fruits extract in body weight, lipid profile and leptin level in Wistar Rats-Induced High Fat Diet Methods This study was an experimental study , pre-post test with control group design. The sample in this study was 30 male rats, 8 weeks old, weight 150-200 gram. Rats were given high fat diet and lerek fruits extract at dose of 50, 100 and 200 mg/kgBW/day for 2 weeks. Lerek fruits was extracted by infusion methods. The results of this study were assayed by SPSS 18. Results Lerek fruit extract 100 mg/kgBW was more potent to reduce body weight gain, triglyseride level and leptin level than lerek fruit extract 50 mg/kgBW, 200 mg.kgBW, negative control and positive control. Conclusion Lerek fruit extracts had a potention to reduce body weight, triglyceride and leptin level. Keywords: Lerek fruit extract â€“ body weight- triglyserida - leptin

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Dietary Genistein Could Modulate Hypothalamic Circadian Entrainment, Reduce Body Weight, and Improve Glucose and Lipid Metabolism in Female Mice

International Journal of Endocrinology ◽

10.1155/2019/2163838 ◽

2019 ◽

Vol 2019 ◽

pp. 1-10 ◽

Cited By ~ 4

Author(s):

Liyuan Zhou ◽

Xinhua Xiao ◽

Qian Zhang ◽

Jia Zheng ◽

Ming Li ◽

...

Keyword(s):

Gene Expression ◽

Body Weight ◽

Lipid Metabolism ◽

Glucose Tolerance ◽

Energy Intake ◽

High Fat Diet ◽

High Fat ◽

Female Mice ◽

Reduce Body Weight ◽

Glucose And Lipid Metabolism

Genistein has beneficial effects on metabolic disorders. However, the specific mechanism is not clearly understood. In light of the significant role of the hypothalamus in energy and metabolic homeostasis, this study was designed to explore whether dietary genistein intake could mitigate the harmful effects of a high-fat diet on glucose and lipid metabolism and whether any alterations caused by dietary genistein were associated with hypothalamic gene expression profiles. C57BL/6 female mice were fed a high-fat diet without genistein (HF), a high-fat diet with genistein (HFG), or a normal control diet (CON) for 8 weeks. Body weight and energy intake were assessed. At the end of the study, glucose tolerance and serum levels of insulin and lipids were analyzed. Hypothalamic tissue was collected for whole transcriptome sequencing and reverse transcription quantitative PCR (RT-qPCR) validation. Energy intake and body weight were significantly reduced in the mice of the HFG group compared with those of the HF group. Mice fed the HFG diet had improved glucose tolerance and decreased serum triacylglycerol, free fatty acids, and low-density lipoprotein cholesterol compared with those fed the HF diet. The HFG diet also modulated gene expression in the hypothalamus; the most abundant genes were enriched in the circadian entrainment pathway. Dietary genistein intake could reduce body weight, improve glucose and lipid metabolism, and regulate hypothalamic circadian entrainment. The ability of genistein intake to influence regulation of the hypothalamic circadian rhythm is important since this could provide a novel target for the treatment of obesity and diabetes.

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