scholarly journals ASSISTED REPRODUCTIVE TECHNOLOGIES IN KAZAKHSTAN IN 2017: SUMMARY REPORT ON EFFICIENCY AND AVAILABILITY

2020 ◽  
pp. 8-12
Author(s):  
V.N. Lokshin ◽  
M.D. Omar ◽  
Sh.K. Karibaeva ◽  
T.M. Dzhusubalieva ◽  
S.B. Baikoshkarova ◽  
...  

The article contains a descriptive analysis to study the characteristics and outcomes of treatment with various methods of assisted reproductive technologies (ART). The report includes data on ART cycles registered by the Kazakhstan Association for Reproductive Medicine for the period from January 1 to December 31, 2017. A total of 10,523 ART treatment cycles and 2,037 newborns were registered in 2017. The accessibility of ART treatment was 583 cycles per million population. The Instruction of the President of the Republic of Kazakhstan given in the Message of September 1, 2020 is an important step to improve the reproductive potential of the country.

2021 ◽  
pp. 9-13
Author(s):  
V.N. Lokshin ◽  
M.D. Omar ◽  
Sh.K. Karibaeva ◽  
T.M. Dzhusubalieva ◽  
S.B. Baykoshkarov ◽  
...  

The article contains descriptive analysis to explore characteristics and results treatment with different types of assisted reproductive technologies (ART). Into the report data of ART cycles registered by the Kazakhstan Association are included reproductive medicine for the period from January 1 to December 31, 2018. In general complexity, 12,185 cycles of ART treatment were registered in 2018, and 3244 newborns were born as a result of their use. The frequency of ART use was 628 cycles per million population. The instruction of the President of the Republic of Kazakhstan in the message of September 1, 2020 is an important step towards improving the reproductive potential of the country.


Author(s):  
P. A. Awoyesuku ◽  
D. A. MacPepple ◽  
B. O. Altraide ◽  
D. H. John

Background: Gynaecological disorders are a particularly common cause of morbidity and mortality among women of reproductive age and a common cause of hospital presentation/admission and surgery. Objective: This study sought to review gynaecological diagnoses and surgeries performed in a tertiary health facility from 2012 to 2017 and its implication for healthcare planning and budgeting. Methodology: This was a retrospective review of all gynaecological diagnoses and surgeries seen in the Rivers State University Teaching Hospital (RSUTH) from 2012 to 2017. Data were retrieved using a proforma comprising of year, gynaecological diagnosis and gynaecological surgeries. Data obtained was entered into Microsoft Excel for descriptive analysis. Results: The proportion of clinic attendees declined from an average of 23% in the first three years (2012-2014) to about 10% in the last three years (2015-2017). The most common gynaecological diagnosis were uterine fibroid (33.3%), infertility 28.1% (primary 5.7%, secondary 22.4%), PID (5.9%), ovarian tumour (4.2%), secondary amenorrhea (3.4%) and pelvic malignancies (3.4%). The commonest major surgeries were myomectomy 441(33.7%), salpingectomy 345(26.4%), hysterectomy 168(12.8%) and cervical cerclage 122(9.3%). The commonest minor surgeries were manual vacuum aspiration 314(41.0%), examination under anaesthesia and biopsy 110(14.3%) and adhesiolysis for synechiae 97(12.6%). The duo of uterine fibroid and infertility made up 50%-70% of all gynaecological diagnoses. Conclusion: This study showed that there has been a steady decline in gynaecological consultations over the years. However, the duo of uterine fibroid and infertility made up half to three-quarter of all gynaecological diagnoses over the 6 years. Infertility and uterine fibroids have a long cause and effect association. Healthcare policies and budgeting should be increased towards tackling these conditions, especially the setting up of a fertility center to provide assisted reproductive technologies and laparoscopy to improve practice and patient outcome.


Author(s):  
Spiridenko G.Yu. ◽  
Petrov Yu.A. ◽  
Palieva N.V.

Infertility is currently a priority problem for women of reproductive age. One of the reasons for this condition may be premature ovarian insufficiency. This is a pathological process causes by primary hypogonadism that occurs in women under 40 years of age. Its prevalence varies from 1:10,000 at the age of 20 to 1:100 at an older age. The absence of specific clinical manifestations of the disease complicates its early diagnosis and timely treatment. This pathological process manifests itself as secondary oligo-or amenorrhea, infertility. Less often, before the onset of reproductive disorders, there are manifestations of estrogenic insufficiency - vasomotor disorders - hot flashes, hyperhidrosis, cephalgia, tachycardia, arterial hypertension, emotional and vegetative disorders-irritability, asthenic manifestations, anxiety, depression, hypo - thymia, decreased libido. The lack of accurate data on etiological factors makes it harder to find methods for preventing this disease. The main direction of treatment is hormone replacement therapy, aimed at eliminating the insufficiency of natural estrogens in the woman's body. The chances of successful realization of the reproductive potential depend on the value of the follicle-stimulating hormone, since its high concentration affects the mitotic activity of granulosa cells of the follicle, which confirms the validity of hormone replacement therapy. The non-occurrence of pregnancy after therapy forces the patient to use assisted reproductive technologies using donor embryos and oocytes, while the effectiveness of in vitro fertilization does not exceed 58%. To prevent this outcome, if a woman has risk factors for developing premature ovarian insufficiency, it is necessary to timely assess the ovarian reserve with the preservation of her own oocytes for subsequent assisted reproductive technologies.


Author(s):  
Anna Rolandovna Purge

The object of this research is the correlation between public law and private law principles in the context regulation of the use of assisted reproductive technologies in the Russian Federation and the Republic of Tajikistan. The subject of this research is the norms of the Russian and Tajik legislation that regulates the procedure of using assisted reproduction technologies, as well as public law and private law principles of their regulation. The scientific novelty of this work lies in carrying out a comprehensive analysis of the relevant problematic on correlation between public law and private law principles in the context of regulation of the use of assisted reproductive technologies in the Russian Federation and the Republic of Tajikistan (taking into account the contradiction and conflicts of law of these legal relations). The author’s special contribution lies formulation of the original proposals for the progressive solution to the problem of correlation between public law and private law principles in regulation of the use of assisted reproductive technologies in the territory of the Russian Federation and the Republic of Tajikistan.


2021 ◽  
Vol 20 (4) ◽  
pp. 26-32
Author(s):  
G. M. Volgareva

Human papillomaviruses (HPV) of the high-risk types cause carcinomas in cervix uteri, vulva, vagina, penis, anus, as well as in certain sites of head and neck – oral cavity, oropharynx, tonsils, larynx. HPV of types 16 and 18 are the most widespread ones. Papillomaviruses of low oncogenic risk, HPV of types 6 and 11, cause recurrent respiratory papillomatosis and anogenital warts. Preventive vaccinations against HPV are not included into the National mandatory immunization schedule in Russia; however, they are being executed in several country areas in a form of regional programs. Substantial contingents are not embraced by the procedures as yet. A family can make decision of its own whether to vaccinate the adolescent child on paid basis. To make decision in favor of vaccination complete awareness is needful on the HPV infection consequences. As far as viruses of the given group became primarily known as cervical cancer etiological agents certain risk persists of “feminization” of notions about unfavorable effects of the HPV infection thus resulting in debates on usefulness of boys’ preventive vaccination.In this connection the purpose of the review was consideration of HPV effects on male reproductive potential. Oncogenic HPVs are frequently found in healthy donors’ sperm. HPV DNA can penetrate from sperm into oocyte under experimental conditions. Seminal fluid of HPV-positive males is a storage tank of the virus as well as the source of its distribution throughout population. DNA of oncogenic HPV was detected in endosomes of seminal lymphocytes. The latter fact opposes the canonic notion of strict HPV epitheliotropy. Correlation exists between the seminal fluid HPV-positivity of a certain man and his fertility drop. Reproductologists believe failures of some married couples when using assisted reproductive technologies may result from partner’s seminal HPV positivity. The successful attempt is known of semen parameters’ normalization in men with reduced fertility after inoculation with the quadrivalent Gardasil vaccine.It seems reasonable to consider the data on unfavorable effects of HPV infection on male reproductive potential as an argument for boys’ preventive HPV vaccination. It would help not only to prevent the HPV-associated oncological diseases in men but the distribution of the given infection around the population as a whole; it would contribute to more successes in solving demographic problems.


2021 ◽  
pp. 36-41
Author(s):  
S.M. Magarmanova ◽  
T.D. Ukbaeva

By definition, platelet-rich plasma (PRP) is a biological product, a part of the plasma fraction of blood, with a platelet concentration exceeding the normal physiological value. PRP is widely used in orthopedics and sports medicine to eliminate pain symptoms by stimulating natural healing processes. In recent years, there have been reports about using of PRP in assisted reproductive technologies. This article presents an overview of information on the mechanism of action PRP, classification of platelet concentrates and its clinical application in the field of reproductive medicine.


2021 ◽  
Vol 19 (4) ◽  
pp. 451-456
Author(s):  
A. V. Salmina ◽  

Background. At present there are no scientifically substantiated data on the problems of introducing assisted reproductive technologies (ART) in the Republic of Belarus. The relevance of developing approaches, organizing opinion polls and processing data on a representative sample of Belarusians does not raise doubts in view of the relationship between social attitudes in the field of reproductive health and the national security of the country. Purpose. Substantiation of medical and sociological study of ART in the population of the Republic of Belarus. Material and methods. The bibliographic analysis included the study of Russian and foreign experience in assessing the sociological aspects of reproductology (materials of Springer Link, Oxford University Press, The New England Journal of Medicine, The British Medical Journal, the SCOPUS database of Elsevier, the EBSCO platform), as well as the analysis of the legislation of the Republic of Belarus in the field of reproductology. Results. In the country, the interests of the party that wants to become a parent (surrogate motherhood, donation) are respected as much as possible. The medicalized approach to the definition of ART methods in Belarus is typical, as in other post-Soviet countries, which are characterized by a classical (nuclear) understanding of the family. Taking into account the current trends in the development of the market for reproductive technologies and those techniques that are used in reproductive centers of the Republic of Belarus, it is necessary in the legislative framework to provide for the rules and possibilities of using such methods as hatching (dissection of the embryo membrane), intracytoplasmic sperm injection, intracytoplasmic sperm injection after selection according to morphological criteria, preimplantation diagnostics. Conclusions. The following areas are relevant for Belarus: 1) study of the awareness of the population of the Republic of Belarus about ART; 2) assessment of social trust in ART on the part of the population; 3) development of technologies for positive reproductive attitudes in society, including the use of ART.


2020 ◽  
Vol 16 ◽  
Author(s):  
Masoumeh Ghafarzadeh

: Assisted Reproductive Technologies (ART) has significantly improved the chances of pregnancy. In Vitro Fertilization (IVF) remains the most widely used ART procedure, which involves a series of steps like ovarian hyperstimulation followed by vaginal oocyte retrieval and in vitro fertilization of the oocytes with sperm, culture of the embryos, and the final transfer of the embryo to the recipient or surrogate recipient. Intracytoplasmic sperm injection (ICSI), another form of ART, is developed to circumvent the problems encountered in IVF. However, the studies have indicated that only about one-third of ART cycles result in live births. This review is designed to provide a comprehensive idea about advances in reproductive medicine in terms of preparation of gametes and implantation.


2019 ◽  
Vol 56 (2) ◽  
pp. 381-404 ◽  
Author(s):  
Catarina Delaunay

This article analyzes couples’ attitudes towards the third-party role in Assisted Reproductive Technologies with gamete donation, and problematizes parenthood and kinship. I base my analysis on 66 in-depth interviews with different ART actors (from beneficiaries to professionals) in France and Portugal, conducted as part of a research project already completed. Special focus is given to 19 interviews with heterosexual and homosexual couples who used third-party reproduction in Europe and the United States. I found a physical and moral detachment operation among heterosexual and lesbian couples vis-a-vis the donor of reproductive potential, who is depersonalized and reduced to a functionality. The objective is to preserve the intimacy of the couple and the autonomy of the parental project. This contrasts with innovative and enlarged family dynamics developed by gay couples, who integrate both female figures (surrogate and oocyte donor) in their children’s family history, through bonding efforts in a logic of reciprocity (gift and counter-gift). The purpose is to reject the negative image of a woman’s body being commodified while preserving the natural appearance of procreation. I conclude that a naturalist conception of kinship persists —one based on shared biogenetic substances that bind together one parent and the donor-conceived child— along with the centrality of biological processes such as pregnancy and childbirth. There are different ways of easing tensions inherent to the contractual intervention of third parties in the reproductive process. ART re-elaborates the line of demarcation between commodities and gifts and between living things and human beings, while reconfiguring family concepts.


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