scholarly journals Sorption properties of suspension ointment with incorporated natural anionic polysaccharides

2020 ◽  
Vol 63 (8) ◽  
pp. 24-30
Author(s):  
Ekaterina A. Trufanova ◽  
◽  
Tatyana V. Tikhonova ◽  

Currently, there is a change in methodologies in the treatment of wounds, as a result of which the share of surgical interventions is reduced and new methods of wound care are introduced using dressings and sorption-application therapy of a new generation. The obtained experimental data on the dissolution of the standard hydrophilic ointment base and the commercial ointment Levomekol® in the Ringer-Locke model solution indicate that in real conditions, the ointment will most likely easily dissolve in physiological fluids, quickly absorb and promote the adhesion of the dressing to the wound. The sorption properties of both individual anionic polysaccharides and their mixtures in various ratios in a Ringer-Locke model solution containing the main exudate cations (Na+, K+, Ca2+) were studied in order to assess the prospects of their use as a solid phase in the development of a suspension ointment with sorption properties. This publication presents the results of the behavior of a suspension ointment with anionic hydrocolloids and a commercial ointment Levomecol® in a Ringer-Locke model solution. It is shown that a mixture of sodium alginate and Kappa-carrageenan in a ratio of 1:2 in the developed suspension ointment retained a significant amount of the model solution (24.5 g/g) in its volume for 24 hours. Increasing the sorption capacity of hydrophilic ointments based on PEO will allow you to Sorb excess exudate, create a microclimate to accelerate healing processes, and reduce tissue trauma when removing the dressing.

Polymer ◽  
2020 ◽  
Vol 190 ◽  
pp. 122191
Author(s):  
Iwona Jakubowska ◽  
Stanisław Popiel ◽  
Mateusz Szala ◽  
Michał Czerwiński ◽  
Maciej Chrunik ◽  
...  

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 321
Author(s):  
Talkybek Jumadilov ◽  
Ruslan Kondaurov ◽  
Aldan Imangazy

The goal of the present work is a comparative study of the effectiveness of the application of intergel systems and molecularly imprinted polymers for the selective sorption and separation of neodymium and scandium ions. The following physico-chemical methods of analysis were used in this study: colorimetry and atomic-emission spectroscopy. The functional polymers of polyacrylic acid (hPAA) and poly-4-vinylpyridine (hP4VP) in the intergel system undergo significant changes in the initial sorption properties. The remote interaction of the polymers in the intergel system hPAA–hP4VP provides mutual activation of these macromolecules, with subsequent transfer into a highly ionized state. The maximum sorption of neodymium and scandium ions is observed at molar ratios of 83%hPAA:17%hP4VP and 50%hPAA:50%hP4VP. Molecularly imprinted polymers MIP(Nd) and MIP(Sc) show good results in the sorption of Nd and Sc ions. Based on both these types of these macromolecular structures, principally new sorption methods have been developed. The method based on the application of the intergel system is cheaper and easier in application, but there is some accompanying sorption (about 10%) of another metal from the model solution during selective sorption and separation. Another method, based on the application of molecularly imprinted polymers, is more expensive and the sorption properties are higher, with the simultaneous sorption of the accompanying metal from the model solution.


Author(s):  
P.О. Nekrasov ◽  
◽  
N.A. Tkachenko ◽  
О.P. Nekrasov ◽  
О.M. Gudz ◽  
...  

Fats as complex mixtures of acylglycerols with lipid and non-lipid substances are an integral part of human nutrition. The presence of acylglycerols of trans-isomers of fatty acids causes many cardiovascular diseases and metabolic disorders. A promising approach to solving the problem of minimizing the content of these undesirable compounds in food recipes is to create a new generation of fat systems, oleogels, which are the subject of this study. High-oleic sunflower oil was used as a dispersion medium of oleogels, which allows obtaining systems with increased resistance to oxidation, as opposed to the oils of traditional kinds. Sunflower seed wax and tocopherols are chosen as a dispersed phase of these fatty systems. The choice of these components was based on their properties to create a three-dimensional structure in oleogels with specified thermomechanical characteristics. Currently, there is a lack of information on the influence of the content of the dispersed phase on the technological parameters of oleogels, namely oxidative resistance and sorption properties. The purpose of the presented work was to study these features of oleogels and establish their dependences on their composition. To solve this problem, the yield surface method is used in the work. The unknown values of the parameter vector were determined by using regression analysis algorithms. Deviation functionality was minimized by finding the appropriate combinations of the experimental series of predictors. A mathematical model was developed which allows predicting oxidative stability and sorption properties of oleogels based on the data on their composition. The suitable mass fractions of the components of the dispersed phase of oleogels have been determined as follows: tocopherol content is 0.10–0.14 wt.% and the sunflower seed wax content is 1.8–4.0 wt.%. The results obtained can serve as a scientific basis for the development of technology for the industrial production of oleogels as new generation fatty systems.


2020 ◽  
Vol 8 (7) ◽  
pp. 481 ◽  
Author(s):  
Tatyana A. Kuznetsova ◽  
Boris G. Andryukov ◽  
Natalia N. Besednova ◽  
Tatyana S. Zaporozhets ◽  
Andrey V. Kalinin

The present review considers the physicochemical and biological properties of polysaccharides (PS) from brown, red, and green algae (alginates, fucoidans, carrageenans, and ulvans) used in the latest technologies of regenerative medicine (tissue engineering, modulation of the drug delivery system, and the design of wound dressing materials). Information on various types of modern biodegradable and biocompatible PS-based wound dressings (membranes, foams, hydrogels, nanofibers, and sponges) is provided; the results of experimental and clinical trials of some dressing materials in the treatment of wounds of various origins are analyzed. Special attention is paid to the ability of PS to form hydrogels, as hydrogel dressings meet the basic requirements set out for a perfect wound dressing. The current trends in the development of new-generation PS-based materials for designing drug delivery systems and various tissue-engineering scaffolds, which makes it possible to create human-specific tissues and develop target-oriented and personalized regenerative medicine products, are also discussed.


2019 ◽  
Vol 185 (5-6) ◽  
pp. e759-e767
Author(s):  
Amanda M Staudt ◽  
Mithun R Suresh ◽  
Jennifer M Gurney ◽  
Jennifer D Trevino ◽  
Krystal K Valdez-Delgado ◽  
...  

Abstract Introduction No published study has reported non-surgical interventions performed by forward surgical teams, and there are no current surgical benchmarks for forward surgical teams. The objective of the study was to describe operative procedures and non-operative interventions received by battlefield casualties and determine the operative procedural burden on the trauma system. Methods This was a retrospective analysis of data from the Joint Trauma System Forward Surgical Team Database using battle and non-battle injured casualties treated in Afghanistan from 2008–2014. Overall procedure frequency, mortality outcome, and survivor morbidity outcome were calculated using operating room procedure codes grouped by the Healthcare Cost and Utilization Project classification. Cumulative attributable burden of procedures was calculated by frequency, mortality, and morbidity. Morbidity and mortality burden were used to rank procedures. Results The study population was comprised of 10,992 casualties, primarily male (97.8%), with a median age interquartile range of 25.0 (22.0–30.0). Affiliations were non-U.S. military (40.0%), U.S. military (35.1%), and others (25.0%). Injuries were penetrating (65.2%), blunt (32.8), and burns (2.0%). Casualties included 4.4% who died and 14.9% who lived but had notable morbidity findings. After ranking by contribution to trauma system morbidity and mortality burden, the top 10 of 32 procedure groups accounted for 74.4% of operative care, 77.9% of mortality, and 73.1% of unexpected morbidity findings. These procedure groups included laparotomy, vascular procedures, thoracotomy, debridement, lower and upper gastrointestinal procedures, amputation, and therapeutic procedures on muscles and upper and lower extremity bones. Most common non-operative interventions included X-ray, ultrasound, wound care, catheterization, and intubation. Conclusions Forward surgical team training and performance improvement metrics should focus on optimizing commonly performed operative procedures and non-operative interventions. Operative procedures that were commonly performed, and those associated with higher rates of morbidity and mortality, can set surgical benchmarks and outline training and skillsets needed by forward surgical teams.


2019 ◽  
Vol 816 ◽  
pp. 228-232
Author(s):  
E.A. Grushevenko ◽  
I.A. Podtynnikov ◽  
A.A. Knyazeva ◽  
O.A. Sharova ◽  
Tatyana S. Anokhina ◽  
...  

Removal oxygenates from wastewater is an important problem of lots of chemical industry. At last decade pervaporation makes a good competitive ability to traditional water-oxygenates separation methods. The goal of this work is to find a new generation of membrane material that can provide increased selectivity oxygenate separation in an example of 1-pentanol and 1-hexanol from the water. In this work were studied following polymers: polyhexylmethylsiloxane, polyheptylmethylsiloxane, and polyoctylmethylsiloxane in comparison with the material, which is wildly used in hydrophobic pervaporation – polydimethylsiloxane. The sorption properties of these polymers were studied and direct correlation sorption and pervaporation properties were demonstrated. It was found that polyheptylmethylsiloxane has higher selectivity than other study polymers: 22 – hexanol/water, 7.3 – pentanol/water.


2006 ◽  
Vol 8 (6) ◽  
pp. 259-264
Author(s):  
Helen Hollinworth
Keyword(s):  

1994 ◽  
Vol 344 ◽  
Author(s):  
Noriko Hasegawa ◽  
Kazuhiro Akanuma ◽  
Taizo Sano ◽  
Masamichi Tsuji ◽  
Yutaka Tamaura

AbstractThe carbon-bearing magnetite (CBM) was prepared by the carbon-deposition on the H2- treated magnetite with CO2 at 300 °C. The CBM reacted with H2O and evolved H2 gas at 300- 350 °C. The surface of the CBM was composed of a new iron(II)oxide / carbon layer (CIOlayer). X-ray diffractometry and chemical analysis showed that the CIOlayer was transformed to an amorphous carbide phase by allowing to stand in Ar stream at 300 °C, which is so reactive as to decompose H2O into H2. The mole ratio of the evolved H2 gas to the evolved CO2 was nearly equal to that in the carbide (Fe3C) decomposition reaction with H2O. During the H2O decomposition, oxygen ions are transferred to the surface layer forming iron oxide. When the carbon-bearing Ni(II)-ferrite (CBNF) was used as the solid phase, the hydrogen evolution reaction takes place without decreasing in the carbon content in the CBNF, and the evolved H2 volume was approximately 8 times higher than that evaluated from the oxidized amount of the iron ions in the CBNF. This result suggests that some amount of oxygen in the CBNF is released while allowing to stand the sample in Ar stream at 300 °C. These H2 evolution reactions can proceed at low temperature of around 300 °C. This will provide us the way to establish a unique chemical heat pump system, where the waste heat around 300 °C be transferred to chemical energy of H2. The surface layer composed of iron(II) oxide/carbon is the key compound for this reaction.


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