Application “Lung Nodule" Software With Lungrads On Early Detection And Follow Up The Pulmonary Nodules By Lung Low Dose CT Findings

2020 ◽  
Author(s):  
Ha Hoang Thi Ngoc
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Pulmonary Nodule ◽  
Low Dose ◽  
False Negative ◽  
Lung Nodule ◽  
Pulmonary Nodules ◽  
Lung Cancer Mortality ◽  
Smoking History ◽  
Low Dose Ct

Background: A pulmonary nodule is defined as a rounded or irregular opacity, well or poorly defined, measuring up to 3 cm in diameter. Early detection the malignancy of nodules has a significant role in decreasing the mortality, increasing the survival time and consider as early diagnosis lung cancer. Content: The main risk factors are those of current or former smokers, aged 55 to 74 years with a smoking history of at least 1 pack-day. Low dose CT: Screening individuals with high risk of lung cancer by low dose CT scans could reduce lung cancer mortality by 20 percent compared to chest X-ray. Radiation dose has to maximum reduced but respect the rule of ALARA (As Low as Resonably Archivable). ACR-LungRADS 2014: Classification of American College of Radiology, LungRADS, is a newly application but showed many advantages in comparison with others classification such as increasing positive predict value (PPV), no result of false negative and cost effectiveness. “Lung nodule” was applied as a smart phone application in order to have a quickly evaluation, especially the malignancy and management face on a pulmonary nodule.

LUNGRADS AND UPDATE OF LUNG NODULES SCREENING BY LOW DOSE COMPUTED TOMOGRAPHY

2015 ◽  
pp. 12-19
Author(s):  
Thi Ngoc Ha Hoang ◽  
Trong Khoan Le
Keyword(s):  
Lung Cancer ◽  
Low Dose ◽  
False Negative ◽  
Lung Nodule ◽  
Lung Cancer Mortality ◽  
Smoking History ◽  
Low Dose Ct ◽  
History Of ◽  
Chest X Ray ◽  
Low Dose Computed Tomography

Background: A pulmonary nodule is defined as a rounded or irregular opacity, well or poorly defined, measuring up to 3 cm in diameter. Early detection the malignancy of nodules has a significant role in decreasing the mortality, increasing the survival time and consider as early diagnosis lung cancer. The main risk factors are those of current or former smokers, aged 55 to 74 years with a smoking history of at least 1 pack-day. Low dose CT: screening individuals with high risk of lung cancer by low dose CT scans could reduce lung cancer mortality by 20 percent compared to chest X-ray. Radiation dose has to maximum reduced but respect the rule of ALARA (As Low as Resonably Archivable). LungRADS 2014: Classification of American College of Radiology, LungRADS, is a newly application but showed many advantages in comparison with others classification such as increasing positive predict value (PPV), no result of false negative and cost effectiveness. Key words: LungRADS, screening lung nodule, low dose CT, lung cancer

scholarly journals Radiomics analysis of pulmonary nodules in low-dose CT for early detection of lung cancer

2018 ◽  
Vol 45 (4) ◽  
pp. 1537-1549 ◽  
Author(s):  
Wookjin Choi ◽  
Jung Hun Oh ◽  
Sadegh Riyahi ◽  
Chia-Ju Liu ◽  
Feng Jiang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Low Dose ◽  
Pulmonary Nodules ◽  
Low Dose Ct

scholarly journals Kezdeti tapasztalatok a HUNCHEST – alacsony dózisú CT-tüdőrákszűrési pilotprogrammal

2018 ◽  
Vol 159 (43) ◽  
pp. 1741-1746 ◽  
Author(s):  
Anna Kerpel-Fronius ◽  
Zsuzsanna Monostori ◽  
Diana Solymosi ◽  
Zsolt Markóczy ◽  
Lívia Rojkó ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Low Dose ◽  
Screening Programme ◽  
Lung Cancer Screening ◽  
Lung Cancer Mortality ◽  
Chronic Obstructive ◽  
International Studies ◽  
Obstructive Pulmonary Disease ◽  
Low Dose Ct ◽  
First Results

Abstract: Introduction: Lung cancer is the cause of death of around 8000 Hungarians each year. Aim: International studies have proved that low-dose CT (LDCT) screening lowers the lung cancer mortality of high risk patients. The HUNCHEST pilot study launched in 2014 studies the possibilities of a lung cancer screening programme in Hungary. The study is also aimed at showing whether there is an increased number of detected lung cancer in the subgroup with chronic obstructive pulmonary disease (COPD). Method: COPD and nonCOPD subjects, smokers and non-smokers are screened with low-dose CT in the 50–79 age group. Results and conclusion: The study is still undergoing recruitement, but in the light of the first results, the principles of the screening programme at the National Korányi Institute of Pulmonology are also presented. Orv Hetil. 2018; 159(43): 1741–1746.

Early detection system using low-dose CT lung cancer screening and related SNP information

2021 ◽  
Author(s):  
Yuta Azuma ◽  
Yoshiki Kawata ◽  
Noboru Niki ◽  
Issei Imoto ◽  
Masahiko Kusumoto ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Screening ◽  
Early Detection ◽  
Low Dose ◽  
Detection System ◽  
Lung Cancer Screening ◽  
Low Dose Ct

scholarly journals Low-dose CT screening can reduce cancer mortality: A meta-analysis

2019 ◽  
Vol 65 (12) ◽  
pp. 1508-1514 ◽  
Author(s):  
Xue Tang ◽  
Guangbo Qu ◽  
Lingling Wang ◽  
Wei Wu ◽  
Yehuan Sun
Keyword(s):  
Lung Cancer ◽  
Cancer Mortality ◽  
Low Dose ◽  
Screening Program ◽  
Meta Analysis ◽  
Lung Cancer Mortality ◽  
Cochrane Library ◽  
Lung Cancers ◽  
Ct Screening ◽  
Low Dose Ct

SUMMARY OBJECTIVE Lung cancer is the leading cause of cancer-related death. To reduce lung cancer mortality and detect lung cancer in early stages, low dose CT screening is required. A meta-analysis was conducted to verify whether screening could reduce lung cancer mortality and to determine the optimal screening program. METHODS We searched PubMed, Web of Science, Cochrane library, ScienceDirect, and relevant Chinese databases. Randomized controlled trial studies with participants that were smokers older than 49 years (smoking >15 years or quit smoking 10 or 15 years ago) were included. RESULTS Nine RCT studies met the criteria. LDCT screening could find more lung cancer cases (RR=1.58, 95%CI=1.25-1.99, P<0.001) and more stage I lung cancers (RR=3.45, 95%CI=2.08-5.72, P<0.001) compared to chest-X ray or the no screening group. This indicated a statistically significant reduction in lung-cancer-specific mortality (RR=0.84, 95%CI=0.75-0.95, P=0.004), but without a statistically reduction in mortality due to all causes (RR=1.26, 95%CI=0.89-1.78, P=0.193). Annually, LDCT screening was sensitive in finding more lung cancers. CONCLUSIONS Low-dose CT screening is effective in finding more lung cancer cases and decreasing the deaths from lung cancer. Annual low-dose CT screening may be better than a biennial screening to detect more early-stage lung cancer cases.

scholarly journals Exploring the impact of screening with low-dose CT on lung cancer mortality in mild to moderate COPD patients: A pilot study

2013 ◽  
Vol 107 (5) ◽  
pp. 702-707 ◽  
Author(s):  
Juan P. de-Torres ◽  
Ciro Casanova ◽  
Jose M. Marín ◽  
Jorge Zagaceta ◽  
Ana B. Alcaide ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pilot Study ◽  
Cancer Mortality ◽  
Low Dose ◽  
Lung Cancer Mortality ◽  
Low Dose Ct ◽  
Copd Patients ◽  
The Impact

Risk stratification of lung cancer patients at initial presentation: A retrospective cohort study.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e20062-e20062
Author(s):  
Jean-Michel Lavoie ◽  
Cheryl Ho ◽  
Sophie Sun
Keyword(s):  
Lung Cancer ◽  
Weight Loss ◽  
Risk Stratification ◽  
Retrospective Cohort ◽  
Low Dose ◽  
Initial Presentation ◽  
Smoking History ◽  
Clinical Factors ◽  
Screening Criteria ◽  
Low Dose Ct

e20062 Background: Early detection and treatment of non-small cell lung cancer (NSCLC) has been shown to improve survival. Current screening guidelines focus on at-risk populations, overlooking a significant proportion of patients (pts) who will develop NSCLC. There is a need for further risk stratification in this group. Methods: A retrospective cohort analysis was conducted on pts referred to the BC Cancer Agency – Vancouver Centre for NSCLC. Records were reviewed for the date of first abnormal imaging and 6 clinical factors (CF) noted by the referring clinician at initial presentation. CFs were: ECOG PS > 2, new-onset dyspnea > MRC 3, chest pain, hemoptysis, weight loss > 10% and systemic symptoms (seizure, bone pain, or paraneoplastic syndrome). Individuals meeting current low-dose CT screening criteria (age 55-74, 30 pack-year smoking history within the last 15 years) were also identified. Results: 435 cases were identified from Jan 1 to Dec 31, 2013; 308 had sufficient information to be included for analysis. Median age: 69; smoking history: 69%; stage: I = 5%, II = 9%, III = 26%, IV = 60%. Multivariate analysis identified 4 of 6 CF were associated with worse overall survival (OS, p < 0.05); hemoptysis and weight loss were not significant predictors and were not retained for analysis. Cases were stratified based by the number of CFs. Pts with no CF had significantly improved OS (median 30.5 mo) compared to those with 1 (12.1 mo), 2 (8.1 mo) or 3-4 (2.5 mo; p < 0.001 for all comparisons) CF. Screening criteria were met for 94 pts (31%). For the other 214 pts (69%), number of CF was 0 = 29%, 1 = 29%, 2 = 33%, 3-4 = 9%. OS was similar whether or not pts were eligible for screening. In the subset of ineligible pts, CFs retained their predictive value (p < 0.05). Conclusions: Four clinical factors predict poor outcomes in pts presenting with abnormal imaging suspicious for NSCLC. In this population, 31% of patients would have been eligible for low-dose CT screening. An additional 49% of patients with abnormal imaging had at least one CF identifiable upon initial contact with a healthcare provider. Determination of key clinical factors may assist in risk stratification of pts ineligible for screening who warrant further investigation for lung cancer.

Long-term follow-up of non-calcified pulmonary nodules (<10 mm) identified during low-dose CT screening for lung cancer

2012 ◽  
Vol 22 (9) ◽  
pp. 1923-1928 ◽  
Author(s):  
Michael M. Slattery ◽  
Claire Foley ◽  
Dermot Kenny ◽  
Richard W. Costello ◽  
P. Mark Logan ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Low Dose ◽  
Pulmonary Nodules ◽  
Ct Screening ◽  
Low Dose Ct ◽  
Long Term Follow Up

scholarly journals Multifactorial Analysis of Mortality in Screening Detected Lung Cancer

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Subba R. Digumarthy ◽  
Ruben De Man ◽  
Rodrigo Canellas ◽  
Alexi Otrakji ◽  
Ge Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Muscle Mass ◽  
Low Dose ◽  
Subcutaneous Fat ◽  
Lung Cancer Mortality ◽  
Data Access ◽  
Smoking History ◽  
Quantitative Prediction ◽  
Cancer Data ◽  
Significant Difference

We hypothesized that severity of coronary artery calcification (CAC), emphysema, muscle mass, and fat attenuation can help predict mortality in patients with lung cancer participating in the National Lung Screening Trial (NLST). Following regulatory approval from the Cancer Data Access System (CDAS), all patients diagnosed with lung cancer at the time of the screening study were identified. These subjects were classified into two groups: survivors and nonsurvivors at the conclusion of the NLST trial. These groups were matched based on their age, gender, body mass index (BMI), smoking history, lung cancer stage, and survival time. CAC, emphysema, muscle mass, and subcutaneous fat attenuation were quantified on baseline low-dose chest CT (LDCT) for all patients in both groups. Nonsurvivor group had significantly greater CAC, decreased muscle mass, and higher fat attenuation compared to the survivor group (p<0.01). No significant difference in severity of emphysema was noted between the two groups (p>0.1). We thus conclude that it is possible to create a quantitative prediction model for lung cancer mortality for subjects with lung cancer detected on screening low-dose CT (LDCT).

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