scholarly journals Ablehnungs- und Umsetzungsraten von Organtransplantationen – mögliche Ursachen und denkbare Auswege

10.38107/017 ◽  
2021 ◽  
Author(s):  
Monika Pfyffer von Altishofen
Keyword(s):  
Organ Donation ◽  
Retrospective Analysis ◽  
Living Wills ◽  
Organ Donors ◽  
Post Mortem ◽  
Legal Situation ◽  
Cantonal Hospital ◽  
Organ Donations ◽  
The Will ◽  
Observation Period

The work deals intensively with the very complex topic of post-mortem organ donation and the question of why it is that not all organs of potential organ donors are considered in transplantation. It covers central questions of the legally and ethically required handling of dying and death. In addition to a presentation of the relevant legal situation, the statistical findings on organ transplants performed in Switzerland during the observation period, the relatively high rates of rejection and low rates of conversion of organ donations by means of retrospective analysis of the data of all in 2013 at their then place of work, the Cantonal Hospital of St. Gallen are made and their results compared with those of the national SwissPOD study. The "primary desirable goal" of the measures taken to promote organ donation appears to the author to be less the "increase in available organs, but rather reflection on dying and one's own death", which is why she would welcome an increase in the number of living wills and organ donation cards available, in order to thereby reduce the emotionally stressful proxy decisions - regardless of the will specified therein.

Introducing an Organ Donor Registry is Saskatchewan

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Amy Zarzeczny ◽  
◽  
Luiza Radu ◽  
Keyword(s):  
Organ Donation ◽  
Public Interest ◽  
Public Awareness ◽  
National Level ◽  
Organ Donor ◽  
Organ Donors ◽  
Media Campaign ◽  
Organ Donations ◽  
Paper Form ◽  
Evaluation Metric

On 3 September 2020, Saskatchewan launched an organ donor registry that allows participants 16 years and older to register their intent to be an organ donor either online or using a paper form. Saskatchewan has historically performed poorly at a national level with low rates of organ donations. Saskatchewan's new registry is intended to increase the numbers of organ donors in the province, while also helping to modernize its organ donation system and ease donation conversations with families. Saskatchewan's introduction of this registry brought the province in line with other provinces and territories across Canada that use similar systems, and provided a response to the surge in public interest around organ donation that followed the Humboldt Bronco bus crash tragedy and related ``Logan Boulet Effect.'' The 2019-2020 and 2020-2021 provincial budgets included dedicated funding for the development and launch of the registry, which was accompanied by a media campaign to increase public awareness. Though it is too early to evaluate the success of the registry, early indications suggest donation rates will be a key evaluation metric. Registries are commonly thought to help increase public awareness of, and support for, organ donation, but improving Saskatchewan's organ donation rates will likely also require companion measures to strengthen the culture and practice of donation in the province.

Organ Donation by Suicides: Sex and Ethnicity

2014 ◽  
Vol 115 (3) ◽  
pp. 948-950
Author(s):  
David Lester ◽  
Dominique Hathaway
Keyword(s):  
Organ Donation ◽  
Sex Difference ◽  
General Public ◽  
Causes Of Death ◽  
Ethnic Difference ◽  
Future Research ◽  
Organ Donors ◽  
Men And Women ◽  
Organ Donations

An analysis of 2,034 actual organ donations by suicides for the years 2008–2010 indicated that women were more likely to be donors than were men and Blacks more likely to donate than were Whites. The sex difference was consistent with the responses of men and women to surveys of the general public about their willingness to become organ donors, but the ethnic difference was the reverse of the responses to surveys of the general public about their willingness to be organ donors. Future research should explore the role of the responses, positive vs negative toward organ donation, of the significant others of those dying from different causes of death, and the extent to which people have signed donor cards.

scholarly journals Evaluation of underidentification of potential organ donors in German hospitals

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0242724
Author(s):  
Grit Esser ◽  
Benedikt Kolbrink ◽  
Christoph Borzikowsky ◽  
Ulrich Kunzendorf ◽  
Thorsten Feldkamp ◽  
...  
Keyword(s):  
Organ Donation ◽  
Rural Areas ◽  
Urban Areas ◽  
Secondary Data ◽  
University Hospital ◽  
Organ Donors ◽  
Rural Regions ◽  
Donor Pool ◽  
Potential Donor ◽  
Organ Donations

Background Since 2010, the number of organ donations in Germany has decreased by one third, mostly due to undetected organ donors. It is unclear, how the undetected potential donor pool is distributed among the different German hospital categories (A = university hospital, B = hospitals with neurosurgery, C = hospitals without neurosurgery) and region types. Methods We performed a nationwide secondary data analysis of all German inpatient cases of the year 2016 (n = 20,063,689). All fatalities were regarded as potential organ donors, in which primary or secondary brain damage was encoded and organ donation was not excluded by a contraindication or a lack of ventilation therapy. Results In 2016, 28,087 potential organ donors were identified. Thereof 21% were found in category A, 28% in category B and 42% in category C hospitals. The contact rate (= organ donation related contacts/ potential organ donors) and realization rate (= realized organ donations/ potential organ donors) of category A, B and C hospitals was 10.6% and 4.6%, 10.9% and 4.8% and 6.0% and 1.7%, respectively. 58.2% of the donor potential of category C hospitals was found in the largest quartile of category C hospitals. 51% (n = 14,436) of the potential organ donors were treated in hospitals in agglomeration areas, 28% (n = 7,909) in urban areas and 21% (n = 5,742) in rural areas. The contact- and realization rate did not significantly differ between these areas. Conclusions The largest proportion of potential organ donors and the lowest realization rate are found in category C hospitals. Reporting and donation practice do not differ between urban and rural regions.

Post-mortem and living donation: ethical and legal issues

2020 ◽  
pp. 66-71
Author(s):  
Gennadiy Petrov ◽  
Marina Erugina ◽  
Irina Krom
Keyword(s):  
Health Care ◽  
Organ Donation ◽  
Legal Issues ◽  
Living Donation ◽  
Organ Donors ◽  
Post Mortem ◽  
Legal Norms ◽  
Ethical And Legal Issues ◽  
Sociological Approaches

The article is devoted to ethical and legal issues of organ donation. The authors analyze the main concepts of the Russian legislation concerning health care in relation to living and postmortem organ donors. The results indicate the need to specify legal norms for this type of health care and assess complex issues of organ donation on the basis of sociological approaches.

Introducing an Organ Donor Registry is Saskatchewan

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Amy Zarzeczny ◽  
◽  
Luiza Radu ◽  
Keyword(s):  
Organ Donation ◽  
Public Interest ◽  
Public Awareness ◽  
National Level ◽  
Organ Donor ◽  
Organ Donors ◽  
Media Campaign ◽  
Organ Donations ◽  
Paper Form ◽  
Evaluation Metric

On 3 September 2020, Saskatchewan launched an organ donor registry that allows participants 16 years and older to register their intent to be an organ donor either online or using a paper form. Saskatchewan has historically performed poorly at a national level with low rates of organ donations. Saskatchewan's new registry is intended to increase the numbers of organ donors in the province, while also helping to modernize its organ donation system and ease donation conversations with families. Saskatchewan's introduction of this registry brought the province in line with other provinces and territories across Canada that use similar systems, and provided a response to the surge in public interest around organ donation that followed the Humboldt Bronco bus crash tragedy and related ``Logan Boulet Effect.'' The 2019-2020 and 2020-2021 provincial budgets included dedicated funding for the development and launch of the registry, which was accompanied by a media campaign to increase public awareness. Though it is too early to evaluate the success of the registry, early indications suggest donation rates will be a key evaluation metric. Registries are commonly thought to help increase public awareness of, and support for, organ donation, but improving Saskatchewan's organ donation rates will likely also require companion measures to strengthen the culture and practice of donation in the province.

scholarly journals Reluctance and willingness for organ donation after death among the Slovene general population

2019 ◽  
Vol 58 (4) ◽  
pp. 155-163
Author(s):  
Nejc Berzelak ◽  
Danica Avsec ◽  
Tanja Kamin
Keyword(s):  
Organ Donation ◽  
Large Scale ◽  
Family Members ◽  
Group Differences ◽  
Organ Donors ◽  
Post Mortem ◽  
Face To Face ◽  
Slovenian Population ◽  
Attitudinal Factors ◽  
Willingness To Donate

Abstract Introduction The paper presents the findings of the first large-scale survey on post-mortem organ donation among the general Slovenian population. It focuses on the reported donation willingness, the barriers to joining the register of organ donors and the position towards consent to donate organs of deceased relatives. Methods A face-to-face survey was conducted on a probability sample of 1,076 Slovenian residents between October and December 2017. The performed analyses included estimations of means and proportions for target variables, an evaluation of between-group differences and a partial proportional odds model to study the relations between organ donation willingness and socio-demographic characteristics. Results The mean reported willingness to donate one’s own organs after death was 3.77 on a 5-point scale, with less than a third of respondents claiming to be certainly willing. Only 6% of those at least tentatively willing to donate organs were certain to join the register of organ donors in the future. The most frequently reported barriers to registration were unfamiliarity with the procedure and a lack of considering it beforehand. The reported willingness to donate organs of a deceased relative strongly depended on the knowledge of the relative’s wishes, yet 80% of the respondents did not discuss their wishes with any family members. Conclusions The findings confirm the gap between the reported donation willingness and joining the register of donors. Future post-mortem organ donation strategies need to consider socio-demographic and attitudinal factors of donation willingness and help stimulate the communication about organ donation wishes between family members.

scholarly journals Soliciting organ donations by medical personnel and organ donation coordinators: A factor analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250249
Author(s):  
Yao-Mei Chuang ◽  
Shan-Shan Yeh ◽  
Chi-Fen Tseng ◽  
Chie-Chien Tseng
Keyword(s):  
Organ Donation ◽  
Medical Staff ◽  
Online Survey ◽  
Medical Personnel ◽  
Research Literature ◽  
Organ Donors ◽  
Snowball Sampling ◽  
Donation Process ◽  
Organ Donations ◽  
Care Training

The literature on organ donation in Taiwan lacks a discussion of the roles of medical staff, organ donors, and transplant coordinators in organ donation. The biggest plight of organ donation is lack of the organ donations. When we probed the possibilities of not finish the organ donation procedure, such as religions, traditions and cultural belief, disease cognitions, and the failure of persuasion or the loss of organ donors. There are lots of research literature shown that the attitude of medical personnel would influence the willingness of organ donation or persuasion. This study considered such personnel and their participation in organ donation, specifically analyzing factors influencing their effectiveness. Snowball sampling was adopted to recruit medical staff, organ donors, and transplant coordinators for an online survey. The results revealed that some participants were unclear as to how to initiate the organ donation process and what practical operations are involved. Even with the necessary qualifications, some participants remained passive when soliciting organ donations in clinical practice. Organ donation coordinators with experience in caring for organ donors who attended organ donation courses performed well in soliciting organ donations. The researchers recommend that training courses on clinical planning and organ donation are incorporated into intensive care training and that they serve as the basis for counsellors soliciting organ donations to increase nurses’ willingness to solicit organ donations.

scholarly journals Detection of Prions in Brain Homogenates and CSF Samples Using a Second-Generation RT-QuIC Assay: A Useful Tool for Retrospective Analysis of Archived Samples

Pathogens ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 750
Author(s):  
Tibor Moško ◽  
Soňa Galušková ◽  
Radoslav Matěj ◽  
Magdalena Brůžová ◽  
Karel Holada
Keyword(s):  
Retrospective Analysis ◽  
Prion Disease ◽  
Second Generation ◽  
Prion Diseases ◽  
Neuropsychiatric Symptoms ◽  
Final Diagnosis ◽  
Post Mortem ◽  
Long Term Storage ◽  
Archived Samples

The possibilities for diagnosing prion diseases have shifted significantly over the last 10 years. The RT-QuIC assay option has been added for neuropsychiatric symptoms, supporting biomarkers and final post-mortem confirmation. Samples of brain homogenates used for final diagnosis, archived for many years, provide the possibility for retrospective studies. We used a second-generation RT-QuIC assay to detect seeding activity in different types of sporadic and genetic prion diseases in archival brain homogenates and post-mortem CSF samples that were 2 to 15 years old. Together, we tested 92 archival brain homogenates: 39 with definite prion disease, 28 with definite other neurological disease, and 25 with no signs of neurological disorders. The sensitivity and specificity of the assay were 97.4% and 100%, respectively. Differences were observed in gCJD E200K, compared to the sporadic CJD group. In 52 post-mortem CSF samples—24 with definite prion disease and 28 controls—we detected the inhibition of seeding reaction due to high protein content. Diluting the samples eliminated such inhibition and led to 95.8% sensitivity and 100% specificity of the assay. In conclusion, we proved the reliability of archived brain homogenates and post-mortem CSF samples for retrospective analysis by RT-QuIC after long-term storage, without changed reactivity.

Can Same-Sex Partners Consent to Organ Donation?

2003 ◽  
Vol 29 (1) ◽  
pp. 31-44
Author(s):  
Roderick T. Chen ◽  
Alexandra K. Glazier
Keyword(s):  
Organ Donation ◽  
Legal Status ◽  
Sex Partners ◽  
Same Sex ◽  
Same Sex Couples ◽  
Civil Union ◽  
Organ Donations ◽  
Domestic Partnerships ◽  
Appeals Court ◽  
Estate Law

As more same-sex couples enter into civil unions and domestic partnerships, the courts and other institutions are beginning to consider the implications of these partnerships in several areas of the law. A Georgia appeals court, for example, recently published the first opinion addressing this issue, ruling that a civil union of two women, obtained in Vermont, was not equivalent to a marriage for the purposes of interpreting a child custody agreement entered into in Georgia. As many observers predicted, the enactment of legislation recognizing same-sex partnerships has profound implications on the practice of family law, trust and estate law and healthcare law.This Article focuses on an area of healthcare law in which the legal status of a civil union or domestic partnership could have significant consequences—organ donations. In particular, it explores whether a civil union or domestic partner is an appropriate party to consent to an organ donation.

scholarly journals Contrasted Epidemiological Patterns of West Nile Virus Lineages 1 and 2 Infections in France from 2015 to 2019

Pathogens ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 908 ◽  
Author(s):  
Cécile Beck ◽  
Isabelle Leparc Goffart ◽  
Florian Franke ◽  
Gaelle Gonzalez ◽  
Marine Dumarest ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
West Nile Virus ◽  
Invasive Disease ◽  
Northern Italy ◽  
Breaking Point ◽  
Organ Donors ◽  
West Nile ◽  
Organ Donations ◽  
History Of ◽  
Lineage 2

Since 2015, annual West Nile virus (WNV) outbreaks of varying intensities have been reported in France. Recent intensification of enzootic WNV circulation was observed in the South of France with most horse cases detected in 2015 (n = 49), 2018 (n = 13), and 2019 (n = 13). A WNV lineage 1 strain was isolated from a horse suffering from West Nile neuro-invasive disease (WNND) during the 2015 episode in the Camargue area. A breaking point in WNV epidemiology was achieved in 2018, when WNV lineage 2 emerged in Southeastern areas. This virus most probably originated from WNV spread from Northern Italy and caused WNND in humans and the death of diurnal raptors. WNV lineage 2 emergence was associated with the most important human WNV epidemics identified so far in France (n = 26, including seven WNND cases and two infections in blood and organ donors). Two other major findings were the detection of WNV in areas with no or limited history of WNV circulation (Alpes-Maritimes in 2018, Corsica in 2018–2019, and Var in 2019) and distinct spatial distribution of human and horse WNV cases. These new data reinforce the necessity to enhance French WNV surveillance to better anticipate future WNV epidemics and epizootics and to improve the safety of blood and organ donations.

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