scholarly journals Pain Improvement After Healing Touch and Massage in Breast Cancer: an Observational Retrospective Study

2020 ◽  
Vol 14 (1) ◽  
pp. 12-20
Author(s):  
Danielle Gentile, PhD ◽  
Danielle Boselli, MS ◽  
Susan Yaguda, MSN,RN ◽  
Rebecca Greiner, PhD, PA-C ◽  
Chasse Bailey-Dorton, MD, MSPH
Keyword(s):  
Breast Cancer ◽  
Comparative Effectiveness ◽  
Pain Reduction ◽  
Outpatient Setting ◽  
Healing Touch ◽  
Chi Square ◽  
Pain Scores ◽  
Breast Cancer Subgroup ◽  
Comparative Effectiveness Study ◽  
Oncology Massage

   Background: Healing Touch (HT) and Oncology Massage (OM) are nonpharmacologic pain interventions, yet a comparative effectiveness study has not been conducted for pain in breast cancer. Purpose: This breast cancer subgroup analysis compared the effectiveness of HT vs. OM on pain. Setting: The research occurred at an outpatient setting at an academic hybrid, multi-site, community-based cancer institute and Department of Supportive Oncology across four regional locations. Participants: Breast cancer outpatients along the cancer continuum who experienced routine clinical, nonexperimentally manipulated HT or OM. Research Design: The study was an observational, retrospective, comparative effectiveness post hoc subanalysis of a larger dataset. Patients reporting pain < 2 were excluded. Pre- and posttherapy pain scores and differences were calculated. Logistic regression modeled posttherapy pain by modality, adjusting for pretherapy pain. The proportions experiencing ? 2-point (clinically significant) pain reduction were compared with chi-square tests. Intervention: The study focused on the first session of either HT or OM. Main Outcome Measures: Pre- and posttherapy pain (range: 0 = no pain to 10 = worst possible pain). Results: A total of 407 patients reported pre- and posttherapy pain scores, comprised of 233 (57.3%) who received HT and 174 (42.8%) who received OM. Pretherapy mean pain was higher in HT (M=5.1, ± 2.3) than OM (M=4.3, ± 2.1) (p < .001); posttherapy mean pain remained higher in HT (M=2.7, ± 2.2) than OM (M=1.9, ± 1.7) (p < .001). Mean difference in pain reduction was 2.4 for both HT and OM. Both HT (p < .001) and OM (p < .001) were associated

scholarly journals Bioenergy and Breast Cancer: A Report on Tumor Growth and Metastasis

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Alice Running ◽  
Mark Greenwood ◽  
Laura Hildreth ◽  
Jade Schmidt
Keyword(s):  
Breast Cancer ◽  
Tumor Cell ◽  
Tumor Size ◽  
Positive Impact ◽  
The United States ◽  
Positive Control ◽  
Healing Touch ◽  
Chi Square ◽  
Cell Injection ◽  
Cancer Tumor

As many as 80% of the 296,000 women and 2,240 men diagnosed with breast cancer in the United States will seek out complementary and alternative medicine (CAM) treatments. One such therapy is Healing Touch (HT), recognized by the National Center for Complementary and Integrative Health (NCCIH) as a treatment modality. Using a multiple experimental groups design, fifty-six six- to eight-week-old Balb/c mice were injected with 4T1 breast cancer tumor cells and randomly divided into intervention and positive control groups. Five days after tumor cell injection, mice in the intervention groups received HT either daily or every other day for 10 minutes by one HT practitioner. At 15 days after tumor cell injection, tumor size was measured, and metastasis was evaluated by a medical pathologist after necropsy. Tumor size did not differ significantly among the groups (F(3,52)=0.75,pvalue = 0.53). The presence of metastasis did not differ across groups (chi-square(3) = 3.902,p=0.272) or when compared within an organ (liver: chi-square(3) = 2.507,p=0.474; lungs: chi-square(3) = 3.804,p=0.283; spleen: chi-square(3) = 0.595,p=0.898). However, these results did indicate a moderate, though insignificant, positive impact of HT and highlight the need for continued research into dose, length of treatment, and measurable outcomes (tumor size, metastasis) to provide evidence to suggest application for nursing care.

HUBUNGAN ANTARA UMUR DAN STATUS PERKAWINAN DENGAN KEJADIAN KANKER PAYUDARA DI INSTALASI BEDAH RUMAH SAKIT UMUM PUSAT DR. MOHAMMAD HOESIN PALEMBANG TAHUN 2012

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Rini Mayasari Rini Mayasari
Keyword(s):  
Breast Cancer ◽  
Marital Status ◽  
Cancer Incidence ◽  
Random Sampling ◽  
Breast Cancer Incidence ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Systematic Random Sampling ◽  
Breast Cancer Event

ABSTRACT Breast cancer on the mark with the growth or uncontrolled growth of cells that are excessive. Factors affecting the incidence of breast cancer include maternal age, marital status, family history, hormone use, radiation, manarche, and obesity. The purpose of this study was to determine the relationship between Age and Marital Status of Mother with Breast Cancer incidence in the Installation Surgeon General Hospital Dr. Mohammad Hoesin Palembang in 2012. The study design was analytical descriptive with the approach in which the independent variables Cross Sectional Age Mother and Status Perkawianan and dependent variables in breast cancer incidence collected at the same time. The study population was all women who develop breast cancer in the Installation General Hospital Surgery Center Dr. Mohammad Hoesin Palembang in 2012 and samples taken by systematic random sampling with a sample of 130 respondents. The results of univariate analysis of data showed that respondents had breast cancer with a percentage of total 58 (44.61%) while respondents who had not had breast cancer totaled 72 by the percentage (63.39%). Respondents by Age Mothers who are at risk amounted to 34 by the percentage (26.15%) while respondents with Age Mothers who are not at risk amounted to 96 by the percentage (73.85%). Respondents by Marital Status is married and the mother who totaled 69 by the percentage (53.07%) and Marital Status with the status of unmarried women totaled 61 by the percentage (46.03%). Of Chi-Square test results found no significant relationship between Age Mothers with Breast Cancer event in which the p value = 0.007, no significant relationship between Marital Status in Breast Cancer event in which the p value = 0.030. Based on the results of the study, researchers suggest counseling efforts, medical knowledge and improve the quality of health services in order to reduce the incidence of breast cancer..   ABSTRAK Kanker payudara di tandai dengan pertumbuhan atau perkembangan tidak terkontrol dari sel-sel yang berlebihan. Faktor-faktor yang mempengaruhi kejadian kanker payudara antara lain umur ibu, status perkawinan, riwayat keluarga, penggunaan hormon, radiasi, manarche, dan obesitas. Tujuan penelitian ini adalah untuk mengetahui hubungan antara Umur Ibu dan Status Perkawinan dengan kejadian Kanker Payudara di Instalasi Bedah Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang Tahun 2012. Desain Penelitian ini adalah deskriptif analitik dengan pendekatan Cross Sectional dimana variabel independen Umur Ibu dan Status Perkawianan dan variabel dependen kejadian kanker payudara dikumpulkan dalam waktu yang bersamaan. Populasi penelitian ini adalah semua ibu yang menderita kanker payudara di Instalasi Bedah Rumah Sakit Umum Pusat Dr. Mohammad Hoesin Palembang Tahun 2012 dan sampel di ambil secara systematic random sampling dengan jumlah sampel 130 responden. Hasil analisis univariat data menunjukan responden yang mengalami Kanker Payudara berjumlah 58 dengan persentase sebesar (44,61%) sedangkan responden yang tidak mengalami Kanker Payudara berjumlah 72 dengan persentase (63,39%). Responden dengan Umur Ibu yang beresiko berjumlah 34 dengan persentase (26,15%) sedangkan responden dengan Umur Ibu yang tidak beresiko berjumlah 96 dengan persentase (73,85%). Responden dengan Status Perkawinan ibu yang berstatus kawin berjumlah 69 dengan persentase (53,07%) dan Status Perkawinan ibu yang berstatus tidak kawin berjumlah 61 dengan persentase (46,03%). Dari hasil uji Chi-Square didapatkan ada hubungan bermakna antara Umur Ibu dengan kejadian Kanker Payudara dimana p Value = 0,007, ada hubungan bermakna antara Status Perkawinan dengan kejadian Kanker Payudara dimana p Value = 0,030. Berdasarkan hasil penelitian, peneliti menyarankan upaya-upaya penyuluhan, pengetahuan tenaga medis dan meningkatkan mutu pelayanan kesehatan guna menurunkan angka kejadian kanker payudara.

Determinan Kejadian Ca Mammae Di Poli Rawat Jalan Bedah Rsud Dr. Achmad Mochtar

2018 ◽  
Vol 3 (3) ◽  
pp. 575
Author(s):  
Neila Sulung ◽  
Rizki Yananda ◽  
Adriani Adriani
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Incidence ◽  
Hormonal Contraception ◽  
Sampling Technique ◽  
Case Control ◽  
Female Breast Cancer ◽  
Chi Square ◽  
Control Approach ◽  
Factors Associated ◽  
Cancer Breast

<p>Cancer is one of the leading causes of death worldwide. In Indonesia every year 1: 3 women per 1000 population are affected by breast cancer. Breast cancer is a cancer that attacks most women. The incidence of breast cancer is currently estimated at 39 per 100,000 population in 2008. The purpose of this study was to determine the factors associated with the risk of female breast cancer in surgical outpatient poly patients at Dr. Achmad Mochtar, Bukittinggi City. This study uses descriptive analytic method with a case control approach. The sampling technique in this study was accidental sampling. The sample in this study were all women diagnosed with breast cancer, amounting to 50 cases and 50 controls with data processing through computerization. The instrument used in this study is a questionnaire. Data analysis was performed using Chi-Square test (α = 0.05). The results showed that the factors associated with the incidence of breast cancer were genetic (p = 0.009), menarche (p = 0.014), menopause (p = 0.016), hormonal contraception (p = 0,045), obesity (p = 0,043), and high food fat (p = 0.028).  Conclusions of the study are factors related to the risk of breast cancer incidence are genetic, menarche, menopause, hormonal contraception, obesity and high-fat foods.<br /> </p><p>Penyakit kanker merupakan salah satu penyebab kematian utama di seluruh dunia. Di Indonesia setiap tahun 1:3 wanita per 1000 penduduk terserang kanker payudara. Kanker payudara merupakan kanker yang paling banyak menyerang perempuan. Angka kejadian kanker payudara saat ini diperkirakan 39 per 100.000 penduduk pada tahun 2008. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan risiko kanker payudara wanita pada pasien poli rawat jalan bedah di RSUD Dr. Achmad Mochtar Kota Bukittinggi. Penelitian ini menggunakan metode <em>deskriptif analitik</em> dengan pendekatan <em>case control</em>. Teknik pengambilan sampel dalam penelitian ini adalah <em>accidental sampling.</em> Sampel dalam penelitian ini adalah semua wanita yang terdiagnosis kanker payudara, berjumlah 50 kasus dan 50 kontrol dengan pengolahan data melalui komputerisasi. Instrument yang digunakan dalam penelitian ini adalah lembar kuisioner. Analisis data dilakukan menggunakan uji <em>Chi-Square </em>(α=0,05). Hasil penelitian menunjukkan faktor yang berhubungan dengan kejadian kanker payudara adalah genetik (p=0,009), <em>menarche</em> (p=0,014;), <em>menopause</em> (p=0,016), kontrasepsi hormonal (p=0,045), <em>obesitas </em>(p=0,043), dan makanan tinggi lemak (p=0,028). Simpulan penelitian adalah faktor yang berhubungan dengan risiko kejadian kanker payudara adalah genetik, <em>menarche, menopause,</em> kontrasepsi hormonal, <em>obesitas</em> dan makanan tinggi lemak.</p>

scholarly journals A Randomized, Controlled, Parallel-Group, Trial on the Effects of Melatonin on Fatigue Associated with Breast Cancer and Its Adjuvant Treatments

2021 ◽  
Vol 20 ◽  
pp. 153473542098834
Author(s):  
Abdolazim Sedighi Pashaki ◽  
Kamal Mohammadian ◽  
Saeid Afshar ◽  
Mohammad Hadi Gholami ◽  
Abbas Moradi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Intervention Group ◽  
Chi Square ◽  
Significance Level ◽  
Severe Fatigue ◽  
Before And After ◽  
Brief Fatigue Inventory ◽  
Chi Square Test ◽  
Student’S T

Objective: Fatigue associated with malignant conditions and their treatments is a disabling condition. This trial assessed the anti-fatigue effects of melatonin coadministration during adjuvant treatment of patients with the breast cancer. Material and Methods: Patients with breast cancer were randomly assigned to receive melatonin or placebo during adjuvant chemotherapy and radiotherapy. Thirty-seven patients were randomly enrolled in each group. The mean ages of patients in the intervention and control groups were 50.47 ± 10.79 and 46.05 ± 10.55 years, respectively ( P = .223). The intervention group received oral melatonin (18 mg/day) from 1 week before until 1 month after the adjuvant radiotherapy. The level of fatigue was assessed before and after intervention using Brief Fatigue Inventory (BFI) in both groups. To analyze data, the Student’s t-test and the Chi-square test were used at a significance level of P ≤ .05. Results: The BFI score was similar before the intervention in both groups, however, after the intervention, it was significantly lower in the melatonin group ( P < .001). Moreover, the frequency of severe fatigue in the melatonin group was significantly lower than in the placebo group after intervention (42.1% vs 83.3%, P < .001). Conclusion: Coadministration of melatonin during adjuvant chemotherapy and radiotherapy of women with breast cancer decreased the levels of fatigue associated with the malignant condition and its treatments.

scholarly journals Withdrawal of inhaled corticosteroids versus continuation of triple therapy in patients with COPD in real life: observational comparative effectiveness study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Helgo Magnussen ◽  
◽  
Sarah Lucas ◽  
Therese Lapperre ◽  
Jennifer K. Quint ◽  
...  
Keyword(s):  
Primary Care ◽  
Triple Therapy ◽  
Comparative Effectiveness ◽  
Inhaled Corticosteroids ◽  
Blood Eosinophil ◽  
Research Database ◽  
Effectiveness Study ◽  
Increased Risk ◽  
Comparative Effectiveness Study ◽  
Oral Corticosteroids

Abstract Background Inhaled corticosteroids (ICS) are indicated for prevention of exacerbations in patients with COPD, but they are frequently overprescribed. ICS withdrawal has been recommended by international guidelines in order to prevent side effects in patients in whom ICS are not indicated. Method Observational comparative effectiveness study aimed to evaluate the effect of ICS withdrawal versus continuation of triple therapy (TT) in COPD patients in primary care. Data were obtained from the Optimum Patient Care Research Database (OPCRD) in the UK. Results A total of 1046 patients who withdrew ICS were matched 1:4 by time on TT to 4184 patients who continued with TT. Up to 76.1% of the total population had 0 or 1 exacerbation the previous year. After controlling for confounders, patients who discontinued ICS did not have an increased risk of moderate or severe exacerbations (adjusted HR: 1.04, 95% confidence interval (CI) 0.94–1.15; p = 0.441). However, rates of exacerbations managed in primary care (incidence rate ratio (IRR) 1.33, 95% CI 1.10–1.60; p = 0.003) or in hospital (IRR 1.72, 95% CI 1.03–2.86; p = 0.036) were higher in the cessation group. Unsuccessful ICS withdrawal was significantly and independently associated with more frequent courses of oral corticosteroids the previous year and with a blood eosinophil count ≥ 300 cells/μL. Conclusions In this primary care population of patients with COPD, composed mostly of infrequent exacerbators, discontinuation of ICS from TT was not associated with an increased risk of exacerbation; however, the subgroup of patients with more frequent courses of oral corticosteroids and high blood eosinophil counts should not be withdrawn from ICS. Trial registration European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (EUPAS30851).

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