scholarly journals Total Antioxidant Capacity, Haematological and Coagulation Parameters after Orthodox Christian Fast

2018 ◽  
Vol 6 (2) ◽  
pp. 284-286 ◽  
Author(s):  
Kali G. Makedou ◽  
Eleni Vagdatli ◽  
Evangelia Patziarela ◽  
Vasiliki Konstantinidou ◽  
Eirini Poimenidou ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Blood Cells ◽  
Total Antioxidant Capacity ◽  
The Body ◽  
Factor Vii ◽  
Fasting Period ◽  
Coagulation Parameters ◽  
Orthodox Christian ◽  
Total Antioxidant ◽  
The Impact

BACKGROUND: Orthodox Christian believers fast abstaining from meat, eggs, dairy products or even fish and oil in certain days of the fasting period, three times a year.AIM: The present study aimed to investigate the impact of a 48-day fast before Easter in blood count parameters, coagulation and antioxidant status.MATERIAL AND METHODS: A total of 35 healthy volunteers, 19-66 years old, were included in the study. White blood cells (WBC), lymphocytes (Lymph), granulocytes (Gran), haemoglobin (Hb), hematocrit (Ht), red blood cells (RBC), mean erythrocyte volume (MCV), platelets (Plt), were measured. Blood coagulation parameters, such as PT, aPTT, fibrinogen concentration, factor VII activity were also determined, and INR (PTsample/PTcontrol) and aPTT ratio (aPTTsample/aPTTcontrol) were calculated. Total antioxidant capacity (TAC) was assayed.RESULTS: Levels of all parameters remained within normal. By the end of the fasting period, lymphocytes and TAC levels were significantly increased (p = 0.011), whereas all the other parameters, except fibrinogen, were significantly decreased.CONCLUSION: Orthodox Christian fast impairs all haematological and coagulation parameters and seems to be beneficial in the body antioxidant protection.

Evaluation of Salivary Antioxidants and Oxidative Stress Markers in Male Smokers

2019 ◽  
Vol 22 (7) ◽  
pp. 496-501
Author(s):  
Fatemeh Ahmadi-Motamayel ◽  
Parisa Falsafi ◽  
Hamidreza Abolsamadi ◽  
Mohammad T. Goodarzi ◽  
Jalal Poorolajal
Keyword(s):  
Oxidative Stress ◽  
Uric Acid ◽  
Free Radicals ◽  
Antioxidant Capacity ◽  
Cigarette Smoke ◽  
Total Antioxidant Capacity ◽  
The Body ◽  
Total Antioxidant ◽  
The Mean ◽  
And Oxidative Stress

Background: Cigarette smoke free radicals can cause cellular damage and different diseases. All the body fluids have antioxidants which protect against free radicals. Objective: The aim of this study was to evaluate salivary total antioxidant capacity and peroxidase, uric acid and malondialdehyde levels in smokers and a nonsmoking control group. Methods: Unstimulated saliva was collected from 510 males. A total of 259 subjects were current smokers and 251 were non-smokers. The levels of salivary total antioxidant capacity, uric acid, peroxidase and malondialdehyde were measured using standard procedures. Data were analyzed with t test and ANOVA. Results: The smokers were younger and dental hygiene index was higher than healthy nonsmoking controls. The mean total antioxidant capacity in smokers and nonsmokers was 0.13±0.07 and 0.21±011, respectively (P=0.001). Smokers had significantly lower peroxidase and uric acid levels than healthy controls. In addition, the mean malondialdehyde levels in the smokers and nonsmokers were 4.55 ±2.61 and 2.79 ±2.21, respectively (P=0.001). Conclusion: Cigarette smoke produces free radical and oxidative stress, causing many side effects. Salivary antioxidant levels decreased and malondialdehyde levels increased in smokers, indicating the high oxidative stress among smokers compared to nonsmokers. Cigarette smoke had deleterious effects on main salivary antioxidants levels.

The impact of total antioxidant capacity on pulmonary function in asthma patients

2012 ◽  
Vol 16 (11) ◽  
pp. 1544-1550 ◽  
Author(s):  
S. Y. Yoon ◽  
T-B. Kim ◽  
S. Baek ◽  
S. Kim ◽  
H-S. Kwon ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Asthma Patients ◽  
Total Antioxidant ◽  
The Impact

scholarly journals Pengaruh pemberian buah naga merah, jambu biji merah, dan kombinasinya terhadap kapasitas antioksidan total dan kadar malondealdehid pada remaja perokok

2020 ◽  
Vol 9 (1) ◽  
pp. 53-60
Author(s):  
Mohammad Zainul Ma'arif ◽  
Suradi Suradi ◽  
Sugiarto Sugiarto
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
The Body ◽  
Smoking Habits ◽  
Control Group ◽  
Male Adolescent ◽  
Dragon Fruit ◽  
Dpph Method ◽  
Total Antioxidant ◽  
The Mean

Background: Smoking habits enhance free radical in the body, which oxidize lipids to form malondialdehyde. One group that is vulnerable to smoking is adolescents. Red dragon fruit and red guava have the possibility as functional foods due to their vitamin and phytochemical content, which have antioxidant effects. This is an opportunity to prevent oxidative stress among adolescent smokers.Objectives: This study aimed to analyze the effect of red dragon fruit, red guava, and its combination to total antioxidant capacity (TAC) and malondialdehyde (MDA) levels among adolescent mild smokers.Methods: This research was an experimental study with a randomized pre-test and post-test control group design. Forty-eight subjects of male adolescent aged 16-17 years with mild smoking habits were divided into four groups: the control group (K), the intervention group with 200 grams of red dragon fruit (P1), 200 grams of red guava (P2), and the combination of both (100 grams red dragon fruit + 100 grams red guava) (P3), for 14 days. TAC examination used the DPPH method and MDA levels using the TBARS method were measured before and after the intervention.Results: After 14 days of intervention, the mean TAC was changed by -0,10±0,76 in the K group, 0,97±1,62 in the P1 group, 0,74±1,39 in the P2 group, and 0,74±1,29 in the P3 group. But the changes of TAC in all intervention groups were not significantly different from the control group (p>0,05). The mean MDA level changed by 0,229±0,371 in the K group, decreased by -0,654±0,922 in the P1 group, -0,592±0,818 in the P2 group, and -1,166±0,670 in the P3 group. The mean difference of the MDA level in all intervention groups was significantly different from the control group (p<0,05).Conclusion: Consumption of red dragon fruit, red guava, or a combination of red dragon fruit and red guava can reduce malondialdehyde levels significantly among male adolescent mild smokers. Whereas the total antioxidant capacity was changed but not significant.

The impact of therapeutic doses of paracetamol on serum total antioxidant capacity

2003 ◽  
Vol 28 (4) ◽  
pp. 289-294 ◽  
Author(s):  
S. L. Nuttall ◽  
J. N. Khan ◽  
G. H. Thorpe ◽  
N. Langford ◽  
M. J. Kendall
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Total Antioxidant ◽  
Therapeutic Doses ◽  
The Impact

scholarly journals Sesame Meal, Vitamin E and Selenium Influence Goats’ Antioxidant Status

Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 392
Author(s):  
Eleni Tsiplakou ◽  
Christina Mitsiopoulou ◽  
Chrysoula Karaiskou ◽  
Marica Simoni ◽  
Athanasios C. Pappas ◽  
...  
Keyword(s):  
Vitamin E ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Oxidative Status ◽  
Protein Carbonyls ◽  
Control Group ◽  
Sesame Meal ◽  
Total Antioxidant ◽  
Mda Content ◽  
The Impact

This study aimed to determine the impact of sesame meal, selenium (Se), and vitamin E (VitE) on goats’ oxidative status. Thirty mid-lactation crossbred goats were divided into five homogeneous groups, and were fed 1 kg of alfalfa hay and 1.2 kg of concentrates daily. The control group (C) received a basal diet. In the concentrates of the treated groups, 10% of the soybean meal was replaced by sesame meal and no extra VitE or Se (SM), or an extra 60 mg of VitE (SME), or 0.1 mg organic Se (SMSe), or their combination (60 mg VitE and 0,1 mg organic Se/kg of concentrate (SMESe). In the plasma of the goats, the dietary treatments did not affect glutathione reductase, glutathione peroxidase, glutathione transferase, catalase, superoxide dismutase activities, malondialdehyde (MDA) content, or the total antioxidant capacity. A reduction and a trend for lower protein carbonyls content was found in goats fed SM (p = 0.03) and SME (p = 0.06) compared to SMESe. In the milk, the lactoperoxidase activity decreased with SMSe and SMESe. A numerical decrease in the total antioxidant capacity and an increase in the MDA content in the milk of the SMESe group compared with the other treated groups was found. In mid-lactation goats, SM improves the oxidative status of both the organism and the milk.

scholarly journals Age and sex related serum changes in nitric oxide and its correlation with plasma lipid profile and lipid peroxidation in healthy ageing individuals

2017 ◽  
Vol 4 (4) ◽  
pp. 1031
Author(s):  
Rohit Sheth ◽  
Tanmay Bhat ◽  
Suchetha Kumari N. ◽  
Harshini Devi Ullal
Keyword(s):  
Nitric Oxide ◽  
Free Radicals ◽  
Antioxidant Capacity ◽  
Lipid Profile ◽  
Elderly People ◽  
Total Antioxidant Capacity ◽  
Antioxidant Status ◽  
The Body ◽  
Lipid Hydroperoxides ◽  
Total Antioxidant

Background: The free radical theory of aging postulates that aging results from the accumulation of deleterious effects caused by free radicals, and the ability of an organism to cope with cellular damage induced by ROS plays an important role in determining organismal lifespan. GSH and SOD functions by donating the proton and in scavenging the superoxide radicals, thereby protecting the body against oxidative stress by scavenging the free radicals produced in the body. Glutathione peroxidase also have similar function, it reduce lipid hydroperoxides to their corresponding alcohols and free hydrogen peroxide to water.Methods: Hundred healthy adults from staff and student community under the age group of 20 to 60 years were recruited. Approximately 5ml blood sample was collected and used for the analysis of lipid profile, MDA and antioxidant status using standard protocol.Results: The lipid profile, MDA and antioxidant status were measured and compared with that of serum nitric oxide levels of 100 healthy individuals of the age 20-60 yrs. Men aged 20-29 years showed significantly higher NO levels compared to corresponding women. There is a significant reduction in total antioxidant capacity in elderly people. With the decrease in NO there is increase in MDA is observed.Conclusions: There is a significant reduction in total antioxidant capacity in elderly people. This reduction in antioxidant capacity implies a defect in antioxidant system, may be due to a reduction in individual antioxidant or may be caused by a non-equilibrium or poor cooperation between them.

Oxidative stress in operating room personnel: occupational exposure to anesthetic gases

2005 ◽  
Vol 24 (11) ◽  
pp. 597-601 ◽  
Author(s):  
A Akbar Malekirad ◽  
A Ranjbar ◽  
K Rahzani ◽  
M Kadkhodaee ◽  
A Rezaie ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Antioxidant Capacity ◽  
Operating Room ◽  
Total Antioxidant Capacity ◽  
Plasma Lipid ◽  
The Body ◽  
Operating Room Personnel ◽  
Total Antioxidant ◽  
Anesthetic Gases

Health professionals exposed to anesthetic gases are at higher risk of reproductive, neurological, hematological, immunological, hepatic and renal system diseases. We investigated if oxidative stress induced by chronic exposure to anesthetic gases has any association with this matter. Plasma lipid peroxidation, total antioxidant capacity and total thiol molecule levels were measured in 66 operating room staff in comparison with 66 controls. The exposed group had a significantly higher level of lipid peroxidation with decreased thiol groups compared to control subjects. Total antioxidant capacity of the body was no different among exposed and not exposed subjects. Increased lipid peroxidation in the blood of exposed subjects warns that oxygen free radicals have increased in the body and thus might attack cells, which, in the longterm, results in multi-organ damage. The remaining blood total antioxidant capacity at normal values is promising and means that other non-thiol antioxidants, such as uric acid, transferrin, ceruloplasmin, albumin, and vitamin antioxidants, such as a-tocopherol and ascorbic acid, have been stimulated to maintain the total anti-oxidant power of the body at normal state.

scholarly journals Hydroalcoholic extract and seed of Foeniculum vulgare improve folliculogenesis and total antioxidant capacity level in F1 female mice offspring

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Fahimeh Pourjafari ◽  
Tahereh Haghpanah ◽  
Seyed Noreddin Nematollahi-Mahani ◽  
Fariba Pourjafari ◽  
Massood Ezzatabadipour
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
The Body ◽  
Control Group ◽  
Lactation Period ◽  
Foeniculum Vulgare ◽  
Marked Rise ◽  
Hydroalcoholic Extract ◽  
Total Antioxidant ◽  
Pregnancy And Lactation

Abstract Background Foeniculum vulgare (fennel) is traditionally suggested for the fertility improvement in Iranian lore due to its antioxidant and phytoestrogen compounds. The present study aimed to investigate the effects of fennel seed and its hydroalcoholic extract on the serum total antioxidant capacity (TAC) and folliculogenesis in offspring exposed to either of the treatments in utero and 56 days after birth (PND 56). Methods Pregnant NMRI mice were randomly divided into 5 groups of 7: extract-treated groups received 500 and 1000 mg/kg/day fennel extract (FE), seed-treated groups received 500 and 1000 mg/kg/day fennel seed (FS), and the control group (CTL) received no treatment. The treatments started from pregnancy day 1 and continued until PND 56. Body and right ovary weights and ovary dimensions were recorded. Hematoxylin and eosin stained ovary sections were prepared to calculate the proportion of different follicles. The level of TAC in the serums was also measured by fluorescence recovery after photo bleaching. Results A marked rise in the body and ovary weights of treated mice was observed compared to the CTL group. The mean number of primordial, primary, pre-antral, and pre-ovulatory follicles as well as corpus luteum size in the treated offspring was significantly higher compared to those of CTL offspring. The atretic follicle number was nonsignificantly lower in either of the treatment groups compared with that in the CTL. However, treatment of animals with 500 mg/kg FE showed a more pronounced effect. Animals in FS500, FE500 and FE1000 groups had a significantly higher level of serum TAC compared to the CTL group. Conclusions Fennel extract and seed administration in pregnancy and lactation period improve offspring’s folliculogenesis. Higher level of TAC in the serum of offspring might have positively altered the folliculogenesis milieu.

scholarly journals The impact of physical activity on total antioxidant capacity and endothelial function: Ikaria Study

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5812-P5812
Author(s):  
E. Oikonomou ◽  
G. Siasos ◽  
C. Chrysohoou ◽  
D. Tousoulis ◽  
M. Zaromitidou ◽  
...  
Keyword(s):  
Physical Activity ◽  
Endothelial Function ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Total Antioxidant ◽  
The Impact

scholarly journals Effects of Xenobiotics on Total Antioxidant Capacity

2012 ◽  
Vol 5 (3) ◽  
pp. 117-122 ◽  
Author(s):  
Carlos FerrariKusano Bucalen
Keyword(s):  
Carbon Monoxide ◽  
Carbon Tetrachloride ◽  
Occupational Exposure ◽  
Antioxidant Capacity ◽  
Blood Cells ◽  
Total Antioxidant Capacity ◽  
Toxic Elements ◽  
Antioxidant Defenses ◽  
Total Antioxidant

ABSTRACT The objective of this article was to review the effects of xenobiotics on total antioxidant capacity (TAC). Measurement of TAC is appropriate for evaluation of the total antioxidant defenses of blood, cells, and different kinds of tissues and organs. TAC is reduced by alcoholism, smoking, and exposure to radiation, herbicides, carbon monoxide, carbon tetrachloride, lead, arsenic, mercury, cadmium, aluminum, and other toxic elements. The test is also an important tool in evaluating environmental and occupational exposure.

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