The impact of therapeutic doses of paracetamol on serum total antioxidant capacity

2003 ◽  
Vol 28 (4) ◽  
pp. 289-294 ◽  
Author(s):  
S. L. Nuttall ◽  
J. N. Khan ◽  
G. H. Thorpe ◽  
N. Langford ◽  
M. J. Kendall
Keyword(s):  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Total Antioxidant ◽  
Therapeutic Doses ◽  
The Impact

The impact of total antioxidant capacity on pulmonary function in asthma patients

2012 ◽  
Vol 16 (11) ◽  
pp. 1544-1550 ◽  
Author(s):  
S. Y. Yoon ◽  
T-B. Kim ◽  
S. Baek ◽  
S. Kim ◽  
H-S. Kwon ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Asthma Patients ◽  
Total Antioxidant ◽  
The Impact

scholarly journals Sesame Meal, Vitamin E and Selenium Influence Goats’ Antioxidant Status

Antioxidants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 392
Author(s):  
Eleni Tsiplakou ◽  
Christina Mitsiopoulou ◽  
Chrysoula Karaiskou ◽  
Marica Simoni ◽  
Athanasios C. Pappas ◽  
...  
Keyword(s):  
Vitamin E ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Oxidative Status ◽  
Protein Carbonyls ◽  
Control Group ◽  
Sesame Meal ◽  
Total Antioxidant ◽  
Mda Content ◽  
The Impact

This study aimed to determine the impact of sesame meal, selenium (Se), and vitamin E (VitE) on goats’ oxidative status. Thirty mid-lactation crossbred goats were divided into five homogeneous groups, and were fed 1 kg of alfalfa hay and 1.2 kg of concentrates daily. The control group (C) received a basal diet. In the concentrates of the treated groups, 10% of the soybean meal was replaced by sesame meal and no extra VitE or Se (SM), or an extra 60 mg of VitE (SME), or 0.1 mg organic Se (SMSe), or their combination (60 mg VitE and 0,1 mg organic Se/kg of concentrate (SMESe). In the plasma of the goats, the dietary treatments did not affect glutathione reductase, glutathione peroxidase, glutathione transferase, catalase, superoxide dismutase activities, malondialdehyde (MDA) content, or the total antioxidant capacity. A reduction and a trend for lower protein carbonyls content was found in goats fed SM (p = 0.03) and SME (p = 0.06) compared to SMESe. In the milk, the lactoperoxidase activity decreased with SMSe and SMESe. A numerical decrease in the total antioxidant capacity and an increase in the MDA content in the milk of the SMESe group compared with the other treated groups was found. In mid-lactation goats, SM improves the oxidative status of both the organism and the milk.

scholarly journals The impact of physical activity on total antioxidant capacity and endothelial function: Ikaria Study

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5812-P5812
Author(s):  
E. Oikonomou ◽  
G. Siasos ◽  
C. Chrysohoou ◽  
D. Tousoulis ◽  
M. Zaromitidou ◽  
...  
Keyword(s):  
Physical Activity ◽  
Endothelial Function ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Total Antioxidant ◽  
The Impact

scholarly journals Influence of crop load on the yield and grape quality of Merlot and Vranac (Vitis vinifera L.) varieties in Trebinje vineyard

2021 ◽  
Vol 117 (4) ◽  
pp. 1
Author(s):  
Mersija DELIĆ ◽  
Fikreta BEHMEN ◽  
Saša MATIJAŠEVIĆ ◽  
Šaćira MANDAL ◽  
Saud HAMIDOVIĆ ◽  
...  
Keyword(s):  
Vitis Vinifera ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Total Phenolics ◽  
Soluble Solids ◽  
Crop Load ◽  
Grape Quality ◽  
Total Antioxidant ◽  
The Impact

<p class="042abstractstekst">The aim of this study was to study the impact of crop load on the yield and grape quality of ‘Merlot’ and ‘Vranac’ (<em>Vitis vinifera</em> L.) in Trebinje vineyard. The crop load levels studied in this trial were 9 buds (V1) and 12 buds (V2) per vine at each variety trained on Lenz-Moser bilateral cordon system. The impact was determined by measurements of yield per vine and grape quality characterized by the contents of total soluble solids, titratable acidity, total phenolics, total flavonoids and by total antioxidant capacity. The measured parameters of grape quality of ‘Merlot’ and ‘Vranac’ were not influenced significantly by crop load levels. V2, compared to the V1, showed the potential for increasing grape yield only for Merlot variety under experimental conditions. The results of this study also showed a positive correlation between total phenolics/flavonoids and total antioxidant capacity of grape berries in both varieties, regardless of crop loads applied.</p>

scholarly journals Total Antioxidant Capacity, Haematological and Coagulation Parameters after Orthodox Christian Fast

2018 ◽  
Vol 6 (2) ◽  
pp. 284-286 ◽  
Author(s):  
Kali G. Makedou ◽  
Eleni Vagdatli ◽  
Evangelia Patziarela ◽  
Vasiliki Konstantinidou ◽  
Eirini Poimenidou ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Blood Cells ◽  
Total Antioxidant Capacity ◽  
The Body ◽  
Factor Vii ◽  
Fasting Period ◽  
Coagulation Parameters ◽  
Orthodox Christian ◽  
Total Antioxidant ◽  
The Impact

BACKGROUND: Orthodox Christian believers fast abstaining from meat, eggs, dairy products or even fish and oil in certain days of the fasting period, three times a year.AIM: The present study aimed to investigate the impact of a 48-day fast before Easter in blood count parameters, coagulation and antioxidant status.MATERIAL AND METHODS: A total of 35 healthy volunteers, 19-66 years old, were included in the study. White blood cells (WBC), lymphocytes (Lymph), granulocytes (Gran), haemoglobin (Hb), hematocrit (Ht), red blood cells (RBC), mean erythrocyte volume (MCV), platelets (Plt), were measured. Blood coagulation parameters, such as PT, aPTT, fibrinogen concentration, factor VII activity were also determined, and INR (PTsample/PTcontrol) and aPTT ratio (aPTTsample/aPTTcontrol) were calculated. Total antioxidant capacity (TAC) was assayed.RESULTS: Levels of all parameters remained within normal. By the end of the fasting period, lymphocytes and TAC levels were significantly increased (p = 0.011), whereas all the other parameters, except fibrinogen, were significantly decreased.CONCLUSION: Orthodox Christian fast impairs all haematological and coagulation parameters and seems to be beneficial in the body antioxidant protection.

scholarly journals Assessment of the Impact of Oxidative Stress on Frozen Seminal Plasma in Fertile and Infertile Men by Examining the Total Antioxidant Capacity

2014 ◽  
Vol 7 (1) ◽  
pp. 25-30
Author(s):  
Violeta S. Rilcheva ◽  
Nina P. Ayvazova ◽  
Danail I. Martinov ◽  
Cvetomir I. Ivanov ◽  
Emiliana I. Konova
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Capacity ◽  
Seminal Plasma ◽  
Total Antioxidant Capacity ◽  
Dna Integrity ◽  
Integrity Test ◽  
Infertile Men ◽  
Total Antioxidant ◽  
The Impact ◽  
Infertile Patients

AbstractThe aim of the study was to explore the impact of oxidative stress on frozen seminal plasma in fertile and infertile men by examining the total antioxidant capacity. Patients: Infertile patients from male infertility clinic with various diagnoses and fertile men. Design: Seminal plasma from proven fertile men [n=50] and infertile patients [n=50] were examined for total antioxidant capacity (TAC) level, semen parameters such as morphology, motility and concentration, and DNA integrity test. Interventions: Seminal plasma TAC measurement by luminometric assay using the TAC assay kit, semen analysis parameters, DNA integrity test. Fertile men showed higher TAC values (median and SD): 1201µM (SD±548), as compared with the infertile patients: 831μM (SD±343). The result from sperm morphology of fertile patients showed a mean percentage of 4.8 % (SD±1.68) whereas the percentage in the infertile group was 2.68% (SD ±1.68). The same group of samples, analyzed for DNA damage showed a mean of DFI 10.38% (SD±5.17%) in fertile men and a mean of DFI 17.22% (SD±7.22%) in infertile men. Total antioxidant capacity of the seminal plasma as measured by the luminоmetric assay is a reliable and simple test for diagnosing and management of male infertility.

scholarly journals Evaluation of Ascorbic Acid Adjuvant Therapy and Oxidative Stress Parameters in Burns Patients

2020 ◽  
pp. 296-306
Author(s):  
A. D. G. Nwosu ◽  
E. N. Ossai ◽  
O. Onwuasoigwe ◽  
F. N. Ahaotu ◽  
J. K. Anieze ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ascorbic Acid ◽  
Adjuvant Therapy ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Controlled Study ◽  
High Dose ◽  
Intravenous Ascorbic Acid ◽  
Total Antioxidant ◽  
The Impact

Background: Burns trauma is associated with considerable morbidity and mortality. Resuscitation of burns patients with high-dose of Ascorbic acid has shown potential for mitigating the injury, but the optimal dose for this indication is unknown. Aim: This study aimed to evaluate the impact of adjuvant therapy with intravenous Ascorbic acid (6g over 24 hours) on indicators of oxidative stress in patients with major burns. Materials and Methods: We conducted a randomized placebo-controlled study on patients with major burns who presented at the National Orthopaedic Hospital, Enugu, Nigeria between August 2017 and July 2020. Each patient in the treatment group received intravenous Ascorbic acid, 6g over 24 hours, while those in the placebo group received Normal saline in the resuscitation fluid. Oxidative stress evaluation was based on measurement of total antioxidant capacity and malondialdehyde in the participants. The level of statistical significance was determined by a p value of <0.05. Results: The study was conducted on 37 burns patients and 15 healthy subjects. At presentation, the burns patients had significantly lower total antioxidant capacity; P=0.006, and higher serum malondialdehyde; P=0.040, compared to the healthy volunteers. The decrease in serum malondialdehyde in the burns patients treated with high-dose Ascorbic acid; 0.9±0.8 nmol/mL, was greater than that in those treated with placebo; 0.3±1.4 nmol/mL. Similarly the increase in total antioxidant capacity in the burns patients treated with high-dose Ascorbic acid; 151.7±116.5 µmol/L was greater than that in those treated with placebo; 58.4±219.1 µmol/L. However these effects weren’t statistically significant. Conclusion: Intravenous Ascorbic acid at a dose of 6g over 24 hours did not significantly alter the indicators of oxidative stress in the burns patients, under the prevailing conditions of the study.

scholarly journals An Impact of Psychological Stress on the Interplay between Salivary Oxidative Stress and the Classic Psychological Stress-Related Parameters

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Nikola M. Stojanović ◽  
Pavle J. Randjelović ◽  
Dragana Pavlović ◽  
Nenad I. Stojiljković ◽  
Ivan Jovanović ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Capacity ◽  
Psychological Stress ◽  
Total Antioxidant Capacity ◽  
Mental Stress ◽  
Test Battery ◽  
Total Antioxidant ◽  
Nitrite Nitrate ◽  
The Impact ◽  
Stress Parameters

Both oxidative and psychological (mental) stress are the likely culprits for several acute and chronic health disturbances, and adequate tests mimicking that are needed. Herein, in controlled laboratory surroundings, a PEBL (Psychology Experiment Building Language) test battery was used to evoke stress-related biological responses followed by tracking changes in saliva parameters. The study objectives were to determine the impact of psychological stress on selected salivatory parameters and to assess the correlation between the determined oxidative and stress parameters. The study was conducted on 36 healthy young subjects, mainly females ( n = 24 ). Before and following the completion of a battery of four PEBL tests, subjects’ saliva samples were collected. Stress-evoking changes in total antioxidant capacity and nitrite/nitrate levels, as oxidative stress parameters, and cortisol and immunoglobulin A (IgA), as parameters of psychological stress, were established and mutually correlated by comparing the values of the evaluated parameters pre- and post-PEBL test. The results showed that there is no change in the total salivary antioxidant capacity ( p > 0.05 ); however, there was a significant increase in nitrites/nitrates levels after the PEBL test ( p = 0.007 ). On the other hand, the determined cortisol levels after the test battery were found to be statistically significantly increased ( p = 0.025 ) when compared to the values obtained before the test, while the levels of IgA were found to be statistically significantly decreased ( p < 0.001 ). The only statistically significant correlation between the changes in the studied parameters was found to be the one between cortisol and IgA levels (Spearman’s Rö = -0.4). These results suggest that the short-term stress induced by the PEBL test does evoke changes in the salivary mental stress-related parameters (an increase in cortisol and nitrite/nitrate levels, and a decrease in IgA), but not in the total antioxidant capacity. They also indicate that the constructed PEBL four-test battery might represent an adequate laboratory stress-inducing paradigm.

scholarly journals Antioxidant Potential of Curcumin—A Meta-Analysis of Randomized Clinical Trials

Antioxidants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1092
Author(s):  
Karolina Jakubczyk ◽  
Aleksandra Drużga ◽  
Janda Katarzyna ◽  
Karolina Skonieczna-Żydecka
Keyword(s):  
Oxidative Stress ◽  
Clinical Trials ◽  
Antioxidant Capacity ◽  
Total Antioxidant Capacity ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Antioxidant Potential ◽  
Average Dose ◽  
Total Antioxidant ◽  
The Impact

Background: Antioxidant potential is defined as the ability to neutralize oxygen free radicals that are generated in excess due to environmental influences. The body’s defense mechanisms often require support in preventing the effects of oxidative stress. The literature data suggest that curcumin has antioxidant activity that can significantly reduce oxidative stress levels. The aim was to assess the impact of curcumin on oxidative stress markers. Methods: PubMed and Embase were searched from database inception until 27 September 2019 for randomized clinical trials in >20 patients treated with curcumin supplements and randomized to placebo/no intervention/physical activity to verify the antioxidant potential of curcumin. Results: Four studies were included in the meta-analysis, three of which were double-blind and one single-blind. A total of 308 participants took part in the research. A total of 40% of the respondents were men. The average age of participants was 27.60 ± 3.79 years. The average supplementation time was 67 days and the average dose of curcumin administered was 645 mg/24 h. Curcumin significantly increased total antioxidant capacity (TAC) (SMD = 2.696, Z = 2.003, CI = 95%, p = 0.045) and had a tendency to decrease malondialdehyde (MDA) concentration (SMD = −1.579, Z = −1.714, CI = 95%, p = 0.086). Conclusions: Pure curcumin has the potential to reduce MDA concentration and increase total antioxidant capacity.

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