scholarly journals High-intensity Interval Training Improves Inflammatory Mediators in Obese Women: Based on the Study of the UCP2 Ala55Val Gene

2021 ◽  
Vol 9 (A) ◽  
pp. 871-875
Author(s):  
Susiana Candrawati ◽  
Emy Huriyati ◽  
Zaenal Muttaqien Sofro ◽  
Lantip Rujito ◽  
Aulia Nury Faza ◽  
...  
Keyword(s):  
Body Weight ◽  
Inflammatory Mediators ◽  
High Intensity ◽  
Interval Training ◽  
T Test ◽  
Wilcoxon Test ◽  
Obese Women ◽  
High Intensity Interval Training ◽  
Before And After ◽  
High Intensity Interval

Background: Increased inflammatory mediators in obesity are associated with metabolic syndrome. Exercise is an effective effort to reduce the incidence of obesity. The High-Intensity Interval Training (HIIT) program is an exercise which include combination of high-intensity exercise and rest periods. The decrease in body fat levels due to physical training will further affect inflammatory mediators such as IL6 and TNFα. Besides training factor, genetic also play a role on obesity. One of the genes that influence obesity is the UCP2 Ala55Val gene. Objectives: This research aims to see the effect of HIIT on the levels of inflammatory mediators in obese patients based on the study of the Ala55Val UCP2 gene. Methods: This study was a Quasi-Experimental Pre and Post Design Without Control Group. Thirty obese women (BMI≥25 kg/m2) were given High-Intensity Interval Training (HIIT) as an intervention by comparing the data before and after the intervention. The training intervention was conducted for 12 weeks, consisting of two weeks of adaptation and ten weeks of HIIT intervention. The body weight, BMI and inflammatory mediators (TNFα and IL 6) before and after the intervention were analyzed using the Dependent T-Test and Wilcoxon Test as a nonparametric test. Independent T-Test and Mann Whitney test used to determine the effect of the UCP2 Ala55Val gene on changes in body weight, BMI and the inflammatory mediator. The test results were considered significantly different if p<0.05. Results: Bivariate analysis using Dependent T-Test showed that HIIT significantly improved Body Weight, BMI and IL6 with p=0.0001. Wilcoxon Test showed that HIIT significantly improved TNFα with p=0.0001. Independent T-Test showed no difference in body weight (p=0.719), BMI (p=0.663) and TNFα (p=0.264) improvement in the two genotypes of the UCP2 Ala55Val gene. Mann Whitney Test showed no difference in IL6 (p=0.288) improvement in the two genotypes of the UCP2 Ala55Val gene. Conclusion: The research concluded that the 12-week HIIT interventions improved inflammatory mediators by reducing IL6 and TNFα in obese women. There was no effect of genetic variation on the response to training intervention.

High-intensity interval training acutely alters plasma adipokine levels in young overweight/obese women

2017 ◽  
Vol 124 (2) ◽  
pp. 149-155 ◽  
Author(s):  
Selma Arzu Vardar ◽  
Aziz Karaca ◽  
Sibel Güldiken ◽  
Orkide Palabıyık ◽  
Necdet Süt ◽  
...  
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
Obese Women ◽  
High Intensity Interval Training ◽  
High Intensity Interval

Immediate and late acute effect of moderate continuous and high intensity interval training on hypertension stage I: case report

2021 ◽  
Vol 1 (4) ◽  
pp. 50-56
Author(s):  
Ana Luísa Freitas Siqueira ◽  
Gabriela Souza Faria ◽  
Pedro De Oliveira Neto ◽  
Maria Paula Fabrício de Andrade ◽  
Bruna Pereira Molina Cruz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Physical Training ◽  
High Intensity ◽  
Interval Training ◽  
Hypotensive Effect ◽  
Acute Effect ◽  
High Intensity Interval Training ◽  
Before And After ◽  
High Intensity Interval ◽  
Training Modalities

Physical training is used in the control of arterial hypertension (AH), especially in patients with higher levels of blood pressure (BP). However, there are still few studies on the effects of physical training on AH in less advanced stages of the disease. The aim of the present study was to assess the immediate and late acute effects of continuous moderate physical training (CMT) and high intensity interval training (HIIT) in patients with mild AH, and to assess which training method induces a greater hypotensive effect. A female patient, 43 years old, sedentary, diagnosed with mild AH (stage 1), taking Losartana 50 mg twice a day was studied. She underwent one CMT and one HIIT session, one week apart. BP measurements were taken before and after each session, as well as 24 hours before and after the sessions. After the physical training sessions, we observed a drop in the patient's BP that lasted up to 60 minutes, and a reduction in blood pressure levels on the day after the training. We conclude that both training modalities were efficient in reducing the BP of the patient with mild acute immediate and delayed hypertension.

Effects of High-Intensity Interval Training Under Normobaric Hypoxia on Cardiometabolic Risk Markers in Overweight/Obese Women

2018 ◽  
Vol 19 (4) ◽  
pp. 356-366 ◽  
Author(s):  
Alba Camacho-Cardenosa ◽  
Marta Camacho-Cardenosa ◽  
Javier Brazo-Sayavera ◽  
Martin Burtscher ◽  
Rafael Timón ◽  
...  
Keyword(s):  
High Intensity ◽  
Cardiometabolic Risk ◽  
Interval Training ◽  
Normobaric Hypoxia ◽  
Risk Markers ◽  
Obese Women ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
Cardiometabolic Risk Markers

scholarly journals Comparison of Two High-Intensity Interval Training Modalities on Cardiometabolic Health in Overweight/Obese Women

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 448-449
Author(s):  
Ozgur Alan ◽  
Emily W. Flanagan ◽  
Lafayette T. Watson ◽  
Andrew N.L. Buskard ◽  
Demet Tekin ◽  
...  
Keyword(s):  
High Intensity ◽  
Interval Training ◽  
Cardiometabolic Health ◽  
Obese Women ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
Training Modalities

scholarly journals High-Intensity Interval Training Improves Lipocalin-2 and Omentin-1 Levels in Men with Obesity

2021 ◽  
Author(s):  
Sirvan Atashak ◽  
Stephen R. Stannard ◽  
Ali Daraei ◽  
Mohammad Soltani ◽  
Ayoub Saeidi ◽  
...  
Keyword(s):  
High Intensity ◽  
Molecular Mechanisms ◽  
Exercise Program ◽  
Interval Training ◽  
Lipocalin 2 ◽  
High Intensity Interval Training ◽  
Cvd Risk ◽  
Before And After ◽  
High Intensity Interval ◽  
And Control

Abstract Objectives: We investigated the effects of 12 weeks of high-intensity interval training (HIIT) on selected circulating adipokines and other cardiovascular diseases (CVD) risks factors in males with obesity. Methods: Thirty males with obesity were randomly assigned to HIIT and control groups. The HIIT group participated in a prescribed exercise program for 12 weeks, three times per week. Blood lipids, insulin resistance, and select serum adipokines were assessed before and after 12 weeks of the intervention period. Results: HIIT improved body composition and lipid profiles (p<0.05) as well as decreased fasting insulin levels (p=0.001) and HOMA-IR (p=0.002) levels. Furthermore, HIIT increased levels of lipocalin-2 (lcn2) (p=0.002) while decreasing omentin-1 levels (p=0.001) in males with obesity. Changes in lcn2 and omentin-1 concentrations correlated with the changes in risk factors in the HIIT group (p<0.05). Conclusions: The results indicate that 12 weeks of supervised HIIT exercise significantly improves both circulating concentrations of lcn2 and omentin-1, two recently described adipokines, and markers of CVD risk in males with obesity. Further research is necessary to understand the molecular mechanisms involved with these changes.

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