scholarly journals A comparison of dysfunctional voiding scores between patients with nocturnal enuresis and healthy children

2014 ◽  
Vol 44 ◽  
pp. 1091-1094
Author(s):  
Özlem BOYBEYİ ◽  
Mustafa Kemal ASLAN ◽  
Emine Gül DURMUŞ ◽  
İsmail ÖZMEN ◽  
Tutku SOYER
Keyword(s):  
Nocturnal Enuresis ◽  
Healthy Children ◽  
Dysfunctional Voiding

scholarly journals Evaluation of depression and self-esteem in children with monosymptomatic nocturnal enuresis: A controlled trial

2014 ◽  
Vol 86 (3) ◽  
pp. 212 ◽  
Author(s):  
Orhan Koca ◽  
Mehmet Akyüz ◽  
Bilal Karaman ◽  
Zeynep Yesim Özcan ◽  
Metin Öztürk ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Nocturnal Enuresis ◽  
Depression Scale ◽  
Self Esteem ◽  
Control Group ◽  
Case Group ◽  
Healthy Children ◽  
Significant Difference ◽  
Monosymptomatic Nocturnal Enuresis ◽  
Age Range

Objectives: Nocturnal enuresis (NE) is very common and is one of the most common causes for patients to be admitted to urology, pediatrics, child psychiatry and child surgery departments. We aimed to investigate the effect on depression and self-esteem of this disorder that can cause problems on person's social development and human relations. Material and methods: 90 patients who were admitted to our clinic with complaints of nocturnal enuresis were enrolled. Investigations to rule out organic causes were performed in this group of patients. Out of them 38 children and adolescents (age range 8-18 years) with primary monosymptomatic nocturnal enuresis (PMNE) agreed to participate in the study In the same period 46 healthy children and adolescents with a similar age range without bed wetting complaint were included in the study as a control group. The age of the family, educational and socioeconomic level were questioned and Piers-Harris Children's Self-Concept Scale (PHCSCS) and Children's Depression Inventory (CDI) forms were filled out. Results: Mean age of the cases (18 females or 47.4% and 20 males or 52.6%) was 10.76 ± 3.82 years whereas mean age of controls (26 females or 56.5% and 20 males or 43.5%) was 10.89 ± 3.11 years. Depression scale was significantly higher (p = 0.001) in the case group than in the control group (10.42 ± 4.31 vs 7.09 ± 4.35). In both groups there was no statistically significant difference by age and sex in terms of depression scale (p > 0.05). Conclusion: NE is widely seen as in the community and is a source of stresses either for children and for their families. When patients were admitted to physicians for treatment, a multidisciplinary approach should be offered and the necessary psychological support should be provided jointly by child psychiatrists and psychologists.

scholarly journals Urinary Aquaporin 2 and Calciuria Correlate with the Severity of Enuresis in Children

2000 ◽  
Vol 11 (10) ◽  
pp. 1873-1881
Author(s):  
GIOVANNA VALENTI ◽  
ANTONIA LAERA ◽  
GIUSEPPE PACE ◽  
GABRIELLA ACETO ◽  
MARIA L. LOSPALLUTI ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Urine Sample ◽  
Western Blotting ◽  
Nocturnal Enuresis ◽  
Urine Samples ◽  
Healthy Children ◽  
Nocturnal Polyuria ◽  
Aquaporin 2 ◽  
Threefold Increase ◽  
Absorptive Hypercalciuria

Abstract. This study examined the hypothesis that nocturnal enuresis might be paralleled by aquaporin 2 (AQP2) urinary excretion. Eighty children who experienced nocturnal enuresis were studied and compared with 9 healthy children. The 24-h urine samples were divided into two portions: night collections and day collections. Creatinine equivalents of urine samples from each patient were analyzed by Western blotting. AQP2 levels were semiquantified by densitometric scanning and reported as a ratio between the intensity of the signal in the day urine sample versus the night urine sample (D/N AQP2 ratio). The D/N AQP2 ratio was 0.59 ± 0.11 (n = 9) in healthy children and increased to 1.27 ± 0.24 (n = 10) in a subpopulation of enuretic children who had low nocturnal vasopressin levels. In enuretic children who displayed hypercalciuria and had normal vasopressin levels, the D/N AQP2 ratio was 1.05 ± 0.27 (n = 8). These data indicate that reduced secretion of vasopressin and absorptive hypercalciuria are independently associated with an approximately twofold increase in the urinary D/N AQP2 ratio. When low nocturnal vasopressin levels were associated with hypercalciuria, a nearly threefold increase in the D/N AQP2 ratio was observed (1.67 ± 0.41, n = 11). In addition, in all enuretic patients tested, the urinary D/N AQP2 ratio correlates perfectly with the severity of the disorder (nocturnal polyuria). The findings reported in this article indicate that urinary AQP2 correlates with the severity of enuresis in children.

scholarly journals Abnormal Degree Centrality in the Right Inferior Frontal Gyrus During Urine Holding in Children With Primary Monosymptomatic Nocturnal Enuresis

2021 ◽  
Author(s):  
Mengxing Wang ◽  
Xiangyu Zheng ◽  
Zhaoxia Qin ◽  
Jun Ma ◽  
Xiaoxia Du
Keyword(s):  
Nocturnal Enuresis ◽  
Inferior Frontal Gyrus ◽  
Brain Regions ◽  
Degree Centrality ◽  
Healthy Children ◽  
Bladder Control ◽  
Monosymptomatic Nocturnal Enuresis ◽  
Urine Storage ◽  
The Right ◽  
Primary Monosymptomatic Nocturnal Enuresis

Abstract Background: Primary monosymptomatic nocturnal enuresis (PMNE) is a common disorder among school-age children. Previous research has suggested that the prefrontal cortex (PFC) is essential to maintain urine storage in bladder control. We hypothesized that children with PMNE have functional deficits in several brain regions, especially the PFC, during urine storage. In this work, we investigated 30 children with PMNE and 28 controls in a state of natural urine holding to evaluate dysfunction in the bladder control network by applying degree centrality (DC) analysis methods based on resting-state functional magnetic resonance imaging. And seed-based functional connectivity (FC) analysis was used to investigate whether the dysfunctional areas exhibited altered FC with other brain regions.Results: Compared with the typical healthy children, the children with PMNE showed increased DC in the right inferior frontal gyrus (IFG). Also, the right IFG showed increased connectivity with the left middle and inferior frontal gyri and the right precuneus extending to the cuneus in the children with PMNE.Conclusion: The children with PMNE showed abnormal neural activity during urine storage and exhibited increased DC in the right IFG and increased connectivity with the left PFC and right precuneus during urine storage. These results suggest that compensatory effects may be associated with the right IFG combined with the precuneus and left PFC working together to maintain high vigilance and improve micturition's inhibition function to preserve the state of urine holding in children with PMNE.

scholarly journals Urinary aquaporin-2 excretion in nocturnal enuresis

2001 ◽  
pp. 435-438 ◽  
Author(s):  
G Radetti ◽  
C Paganini ◽  
F Rigon ◽  
L Gentili ◽  
U Gebert ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Nocturnal Enuresis ◽  
Plasma Osmolality ◽  
Urine Osmolality ◽  
Posterior Lobe ◽  
Healthy Children ◽  
Serum Concentrations ◽  
Aquaporin 2 ◽  
Magnetic Resonance Imaging Mri ◽  
Study Participants

OBJECTIVE: To evaluate the role of the arginine vasopressin (AVP)-aquaporin-2 (AQP-2) axis in the pathogenesis of nocturnal enuresis. STUDY PARTICIPANTS: Twelve children (seven male and five female), aged 11.6+/-4.3 (6.7-15.6) years, suffering from primary monosymptomatic nocturnal enuresis and 12 healthy children, matched for sex and age. Enuretic children were further subdivided into responders and non-responders to treatment with 1-desamino-8-d-AVP (DDAVP). METHODS: Serum concentrations of AVP, and plasma and urine osmolality were measured at night (0100, 0400 and 0700 h), together with nocturnal urinary excretion of AQP-2 (2000-0800 h). Magnetic resonance imaging (MRI) of the pituitary gland was carried out to evaluate the amount of AVP stored in the posthypophysis. RESULTS: Mean AVP serum concentrations were similar in patients and controls. Urinary AQP-2 was also similar in patients and controls, but responders had a significantly lower level of AQP-2 than non-responders (P<0.005). Plasma osmolality was greater in patients than in controls (P<0.001), whereas urinary osmolality was similar in both groups. No difference in the ratio of the signal intensity of the posterior lobe of the hypophysis to that of the pons (AVP content) was found between patients and controls or between responders and non-responders. CONCLUSION: A decreased urinary excretion of AQP-2 is associated with, and seems to have a role in, nocturnal enuresis, at least in some children, and this could also explain why only some of them respond to DDAVP treatment.

scholarly journals Voiding dysfunction in children aged five to 15 years

2004 ◽  
Vol 132 (9-10) ◽  
pp. 313-317
Author(s):  
Dragana Karaklajic ◽  
Amira Peco-Antic
Keyword(s):  
Vesicoureteral Reflux ◽  
Urge Incontinence ◽  
Nocturnal Enuresis ◽  
Voiding Dysfunction ◽  
Common Type ◽  
Dysfunctional Voiding ◽  
Urge Syndrome

Voiding dysfunction in children was analyzed in 91 patients in a period from January 1st to October 1st 1998. Most of the patients had functional voiding disorder (92.31%), and only 7.69% manifested monosymptomatic night enuresis. The number of girls was bigger in the group of patients with voiding dysfunction while the boys were predominant in the group with mono-symptomatic nocturnal enuresis. More than a half of children with functional voiding disorder had repeated urinal infections (58.23%), incontinence (93.49%), need for urgent voiding (68.13%), and vesicoureteral reflux (47.61%). The most common type of voiding dysfunction was urge syndrome/urge incontinence. The incidence of dysfunctional voiding disorder was more often in children with scaring changes of kidney which were diagnosed by static scintigraphy.

scholarly journals Primary Monosymptomatic Nocturnal Enuresis in Children and Correlation with Sleep Disorders in Arak, Iran

2021 ◽  
Vol 19 (3) ◽  
Author(s):  
Maryam Khalajmehri ◽  
Parsa Yousefichaijan ◽  
Masoud Rezagholizamenjany ◽  
Bahman Salehi ◽  
Bahman Sadeghi-Sedeh ◽  
...  
Keyword(s):  
Sleep Disorders ◽  
Sleep Disorder ◽  
Nocturnal Enuresis ◽  
Sleep Disturbances ◽  
Control Group ◽  
Case Group ◽  
Healthy Children ◽  
Chi Square ◽  
Monosymptomatic Nocturnal Enuresis ◽  
Primary Monosymptomatic Nocturnal Enuresis

Background: Nocturnal enuresis is a symptom defined as enuresis in children over 5 years of age that might have mutual connection to sleep disturbances. This condition might be a stressful factor for children and their families. Objectives: This study aimed to find the correlation between primary monosymptomatic nocturnal enuresis (PMNE), as a stressful factor and sleep disorders. Methods: This case-control study was conducted on 132 children, including 66 children with nocturnal enuresis as the case group and 66 healthy children as the control group. The two groups were homogenous in age, gender, and other demographic characteristics. The organized sleep disorder questionnaire based on sleep disorder diagnostic criteria (using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision) was used in this study. The correlation between PMNE and sleep disorders was investigated based on the Chi-square test on SPSS software (version 23). Results: The mean scores of the subjects with sleep disorders in the control and case groups were 0.38 ± 0.78 and 2.24 ± 1.73, respectively. Therefore, there were significant differences between the two groups in sleep disorders (P = 0.001). In addition, primary insomnia, hypersomnia, circadian sleep rhythm, and sleep terror disorders in the case group were higher than the control group (P = 0.001). Conclusions: The PMNE has been defined as a risk factor for sleep disorders.

scholarly journals Decreased vitamin D levels in children with primary mono-symptomatic nocturnal enuresis

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Farida M. El-Baz ◽  
Marian G. R. Abdelsayed ◽  
Aziza S. Abdel-Hafeez ◽  
Reham I. Abdelmageed
Keyword(s):  
Vitamin D ◽  
Nocturnal Enuresis ◽  
Serum Vitamin ◽  
Study Groups ◽  
Healthy Children ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Egyptian Children ◽  
25 Hydroxyvitamin D

Abstract Background Nocturnal enuresis (NE) is a common voiding problem in pediatric populations. Relatively, few studies have investigated the 25-Hydroxyvitamin D and NE associations in children, which may open up a new research area on the effect of vitamin D as nutritional therapy in the treatment of NE. The aim of this study was to determine the level of 25-hydroxyl vitamin D among children and adolescents with nocturnal enuresis in comparison to non-enuretic Egyptian children. Results Fifty children (24 females, 26 males) who presented with primary mono-symptomatic nocturnal enuresis (PMNE) and 50 healthy children (23 females, 27 males) were recruited in this study. A structured questionnaire focusing on demographic, socioeconomic, and frequency of bed-wetting were collected, and vitamin D serum levels were assessed in all children. In the NE group, the mean value of serum vitamin D levels was lower than the control (19.0 ± 6.5 versus 23.89 ± 4.19; P < 0.0001). Serum 25-hydroxyvitamin D levels were abnormal (< 20 ng/mL) in 46% of children with NE and 16% of controls (P < 0.001). The higher bed-wetting frequencies were associated with lower levels of 25(OH) D (Every night: 7.0 ± 1.4, 3–5 time/week: 11.2 ± 1.7, 1–3 times/week: 17.6 ± 3.7, < 2times/week: 22.4 ± 2.9, Once/6 month: 24.1 ± 4.3 (ng/ml), P < 0.001). Conclusion A difference in serum 25-hydroxyvitamin D levels was found between the two study groups. There is a need for more studies to explain vitamin D deficiency in larger series so that this test can be used in regular enuretic child investigations.

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