scholarly journals Significance of Ratio of Omega-3 and Omega-6 in Human Health with Special Reference to Flaxseed Oil

2015 ◽  
Vol 10 (1-4) ◽  
pp. 1-6 ◽  
Author(s):  
Kshitij Bhardwaj ◽  
Narsingh Verma ◽  
R.K. Trivedi ◽  
Shipra Bhardwaj ◽  
Neha Shukla
Keyword(s):  
Special Reference ◽  
Human Health ◽  
Flaxseed Oil ◽  
Omega 3 ◽  
Omega 6

scholarly journals Flaxseed Oil Supplementation Increases Long‐chain Omega‐3 and Omega‐6 Fatty Acids in Plasma

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Carol L Cheatham ◽  
Kelly W Sheppard ◽  
Daniel S Lupu ◽  
Mihai D Niculescu
Keyword(s):  
Fatty Acids ◽  
Flaxseed Oil ◽  
Omega 3 ◽  
Omega 6 ◽  
Long Chain

scholarly journals Overconsumption of Omega-6 Polyunsaturated Fatty Acids (PUFAs) versus Deficiency of Omega-3 PUFAs in Modern-Day Diets: The Disturbing Factor for Their “Balanced Antagonistic Metabolic Functions” in the Human Body

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Abeba Haile Mariamenatu ◽  
Emebet Mohammed Abdu
Keyword(s):  
Fatty Acids ◽  
Platelet Aggregation ◽  
Polyunsaturated Fatty Acids ◽  
Human Health ◽  
Linolenic Acid ◽  
Human Body ◽  
Acyl Chain ◽  
Lipid Mediators ◽  
Omega 3 ◽  
Omega 6

Polyunsaturated fatty acids (PUFAs) contain ≥2 double-bond desaturations within the acyl chain. Omega-3 (n-3) and Omega-6 (n-6) PUFAs are the two known important families in human health and nutrition. In both Omega families, many forms of PUFAs exist: α-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) from the n-3 family and linoleic acid (LA), dihomo-γ-linolenic acid (DGLA), and arachidonic acid (AA) from the n-6 family are the important PUFAs for human health. Omega-3 and Omega-6 PUFAs are competitively metabolized by the same set of desaturation, elongation, and oxygenase enzymes. The lipid mediators produced from their oxidative metabolism perform opposing (antagonistic) functions in the human body. Except for DGLA, n-6 PUFA-derived lipid mediators enhance inflammation, platelet aggregation, and vasoconstriction, while those of n-3 inhibit inflammation and platelet aggregation and enhance vasodilation. Overconsumption of n-6 PUFAs with low intake of n-3 PUFAs is highly associated with the pathogenesis of many modern diet-related chronic diseases. The volume of n-6 PUFAs is largely exceeding the volume of n-3PUFAs. The current n-6/n-3 ratio is 20-50/1. Due to higher ratios of n-6/n-3 in modern diets, larger quantities of LA- and AA-derived lipid mediators are produced, becoming the main causes of the formation of thrombus and atheroma, the allergic and inflammatory disorders, and the proliferation of cells, as well as the hyperactive endocannabinoid system. Therefore, in order to reduce all of these risks which are due to overconsumption of n-6 PUFAs, individuals are required to take both PUFAs in the highly recommended n-6/n-3 ratio which is 4-5/1.

scholarly journals The Sources, Synthesis and Biological Actions of Omega-3 and Omega-6 Fatty Acids in Red Meat: An Overview

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1358
Author(s):  
Eric N. Ponnampalam ◽  
Andrew J. Sinclair ◽  
Benjamin W. B. Holman
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Crop Production ◽  
Large Scale ◽  
The Body ◽  
Short Chain ◽  
Farm Animals ◽  
Omega 3 ◽  
Health And Wellbeing ◽  
Omega 6

The maximisation of available resources for animal production, food security and maintenance of human–animal wellbeing is important for an economically viable, resilient and sustainable future. Pasture and forage diets are common sources of short chain omega-3 (n-3) polyunsaturated fatty acids (PUFA), while grain-based and feedlot diets are common sources of short chain omega-6 (n-6) PUFA. Animals deposit n-3 and n-6 PUFA as a result of their direct consumption, as feeds or by synthesis of longer chain PUFA from short chain FA precursors in the body via desaturation and elongation processes. Research conducted over the last three decades has determined that the consumption of n-3 PUFA can improve the health and wellbeing of humans through its biological, biochemical, pathological and pharmacological effects. n-6 PUFA also play an important role in human health, but when consumed at high levels, are potentially harmful. Research shows that current consumption of n-6 PUFA by the human population is high due to their meal choices and the supplied food types. If consumption of n-3 PUFA from land- and marine-based foods improves human health, it is likely that these same food types can improve the health and wellbeing of livestock (farm animals) by likewise enhancing the levels of the n-3 PUFA in their circulatory and tissue systems. Modern agricultural systems and advanced technologies have fostered large scale animal and crop production systems. These allow for the utilisation of plant concentrate-based diets to increase the rate of animal growth, often based on economics, and these diets are believed to contribute to unfavourable FA intakes. Knowledge of the risks associated with consuming foods that have greater concentration of n-6 PUFA may lead to health-conscious consumers avoiding or minimising their intake of animal- and plant-based foods. For this reason, there is scope to produce food from plant and animal origins that contain lesser amounts of n-6 PUFA and greater amounts of n-3 PUFA, the outcome of which could improve both animal and human health, wellbeing and resilience to disease.

scholarly journals Flaxseed Oil Attenuates Monosodium Glutamate-Induced Brain Injury via Improvement of Fatty Acids Contents

2019 ◽  
Vol 12 (2) ◽  
pp. 527-532
Author(s):  
Eman R. Youness ◽  
Jihan S. Hussein ◽  
Amr M. M. Ibrahim ◽  
Fatma E. Agha
Keyword(s):  
Fatty Acids ◽  
Monosodium Glutamate ◽  
Treated Group ◽  
Brain Dysfunction ◽  
Flaxseed Oil ◽  
Albino Rats ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Omega 6 ◽  
Wistar Albino Rats

Monosodium glutamate (MSG) is immensely globally used as a food aroma and additive, several studies indicated its toxicity in different body organs. Here, we aimed to evaluate brain dysfunctions in experimental animal that administered MSG and appreciate the beneficial role of flaxseed oil in attenuating this effect. In this study, forty male Wistar albino rats were divided into four groups; control, flaxseed oil, MSG and treated groups. Kidney and liver functions were estimated, malondialdehyde (MDA) and paraoxonase (PON1) were measured by colorimetric methods. Blood fatty acids and neurotransmitters parameters were estimated by HPLC. Our results revealed that MSG administration significantly increased oxidative stress and omega-6 fatty acids and decreased brain neurotransmitters as well as omega-3 fatty acids (ω-3 FA). Whereas treatment with flaxseed oil significantly attenuated all these disadvantages. The results of this study indicated that MSG was responsible for brain dysfunction that appeared in disturbances of neurotransmitters levels. In addition , the administration of omega-3 fatty acids in treated group effectively attenuated this dysfunctions through replacing omega-6 fatty acids in the neurocells by omega-3 fatty acids that represent in our study by flaxseed oil.

scholarly journals Human Health Implications of Omega-3 and Omega-6 Fatty Acids in Blubber of the Bowhead Whale (Balaena mysticetus)

ARCTIC ◽  
2009 ◽  
Vol 59 (2) ◽  
Author(s):  
John E. Reynolds, III ◽  
Dana L. Wetzel ◽  
Todd M. O'Hara
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Bowhead Whale ◽  
Balaena Mysticetus ◽  
Omega 3 ◽  
Health Implications ◽  
Omega 6

scholarly journals Fatty Acid Contents and Stability of Oyster Nut Oil (Telfairia pedata) Compared to Flaxseed and Sunflower Oil

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Emmanuel Mwakasege ◽  
Anna Treydte ◽  
Otmar Hoeglinger ◽  
Neema Kassim ◽  
Edna Makule
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Sunflower Oil ◽  
Inflammatory Diseases ◽  
Good Health ◽  
Flaxseed Oil ◽  
Omega 3 ◽  
Alpha Linolenic Acid ◽  
Keeping Quality ◽  
Omega 6

The selection of healthy fats for consumption is important. Linoleic acid (LA) (omega-6) and alpha-linolenic acid (ALA) (omega-3) are essential polyunsaturated fatty acids required for the maintenance of good health; however, LA derivatives such as arachidonic acid (AA) are associated with the onset of inflammatory diseases, and both are prone to oxidation and deterioration. This study compared the fatty acid contents, peroxide value (PV), p-anisidine value (p-AV), and free fatty acids (FFA) of the oyster nut oil with refined sunflower, nonrefined sunflower, and flaxseed oil stored at 27°C for 40 days. Flaxseed oil had significantly high ALA content (59.8%) compared to 0.1-0.5% for oyster nut and sunflower oil brands. The LA content was high in sunflower brands (50.3-52.8%) compared to the oyster nut (48%) and flaxseed oil 14.7%. Oleic acid was lower in oyster nut oil (8.6%) and flaxseed oil 15.8% compared to sunflower brands (35.7-38.2%). As a consequence, oyster nut and flaxseed recorded higher PV of 4.35-2.88 mEq O2/kg and FFA 0.26-0.47% compared to sunflower brands. The p-AV recorded small values which were not significantly different in all samples. Although oyster nut is widely consumed by pregnant and lactating women across Africa, its keeping quality in nonrefined form is low compared to flaxseed and sunflower oil as shown in this study. Hence, the fatty acid contents in oyster nuts should be consumed in other alternative forms such as flour and roasted kernels rather than its oil when in nonrefined form. This study will enable the consumption balance of omega-6/omega-3 fatty acids and the keeping quality of oils which is key to health.

scholarly journals Cultivation of promising oil flax varieties in the Trans-Urals

2021 ◽  
Vol 37 ◽  
pp. 00109
Author(s):  
Marja Karpova ◽  
Nina Roznina ◽  
Dmitriy Paliy ◽  
Elena Lapina ◽  
Oksana Galyuta
Keyword(s):  
Blood Pressure ◽  
Linseed Oil ◽  
Short Fiber ◽  
Flaxseed Oil ◽  
Omega 3 ◽  
Drying Oils ◽  
Blood Clots ◽  
Oncological Diseases ◽  
Omega 6 ◽  
Ancient Times

In Russia, flax has been cultivated since ancient times; fiber linen fabrics and other products were produce to meet needs of the population and for exchange. Oil flax was a less common crop, but its cultivation is of great interest.In recent years, worldwide interest in the use of flaxseed oil has increased due to its healing properties and high content of linolenic acid. Flaxseed oil removes cholesterol, improves the metabolism of proteins and fats, normalizes blood pressure, and reduces the likelihood of blood clots and tumors. Flaxseed oil reduces the risk of cardiovascular and oncological diseases and allergies. Whole flaxseed is used in various countries as an additive to bread and cereal mixtures. Proteins extracted from flaxseed have a gelatinizing effect and can be used in cooking.Oil flax is a valuable food and industrial crop (seeds, oil, short-fiber, cake and meal). Its seeds contain up to 50% of the most valuable vegetable oil which is the richest source of omega-3 and omega-6. Linseed oil ranks first among industrial oils by the volume of production. It is used in the manufacture of environmentally friendly varnishes, paints, drying oils, which serve as a standard for reliability and durability. Linseed oil is widely used in printing, rubber, electrical and many other industries.

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