Towards Process-of-Care Aware Emergency Department Information Systems

2011 ◽  
pp. 1916-1929
Author(s):  
Andrzej S. Ceglowski ◽  
Leonid Churilov
Keyword(s):  
Information Systems ◽  
Critical Role ◽  
Process Models ◽  
Practical Significance ◽  
Patient Treatment ◽  
Process Of Care ◽  
Novel Approach ◽  
Patient Complexity ◽  
Injured Patients

The critical role of emergency departments (EDs) as the first point of contact for ill and injured patients has presented significant challenges for the elicitation of detailed process models. Patient complexity has limited the ability of ED information systems (EDIS) in prediction of patient treatment and patient movement. This article formulates a novel approach to building EDIS Activity Views that paves the way for EDIS that can predict patient workflow. The resulting Activity View pertains to “what is being done,” rather than “what experts think is being done.” The approach is based on analysis of data that is routinely recorded during patient treatment. The practical significance of the proposed approach is clinically acceptable, verifiable, and statistically valid process-oriented clusters of ED activities that can be used for targeted process elicitation, thus informing the design of EDIS. Its theoretical significance is in providing the new “middle ground” between existing “soft” and “computational” process elicitation methods.

Towards Process-of-Care Aware Emergency Department Information Systems

2011 ◽  
pp. 241-254
Author(s):  
Andrzej S. Ceglowski ◽  
Leonid Churilov
Keyword(s):  
Information Systems ◽  
Critical Role ◽  
Process Models ◽  
Practical Significance ◽  
Patient Treatment ◽  
Process Of Care ◽  
Novel Approach ◽  
Patient Complexity ◽  
Injured Patients

The critical role of emergency departments (EDs) as the first point of contact for ill and injured patients has presented significant challenges for the elicitation of detailed process models. Patient complexity has limited the ability of ED information systems (EDIS) in prediction of patient treatment and patient movement. This article formulates a novel approach to building EDIS Activity Views that paves the way for EDIS that can predict patient workflow. The resulting Activity View pertains to what is being done, rather than what experts think is being done. The approach is based on analysis of data that is routinely recorded during patient treatment. The practical significance of the proposed approach is clinically acceptable, verifiable, and statistically valid process-oriented clusters of ED activities that can be used for targeted process elicitation, thus informing the design of EDIS. Its theoretical significance is in providing the new middle ground between existing soft and computational process elicitation methods.

Critical Role of Supply Chain Decoupling Point in Mass Customisation from Its Upstream and Downstream Information Systems Point of View

2011 ◽  
pp. 185-196
Author(s):  
S. Saghiri
Keyword(s):  
Supply Chain ◽  
Information Systems ◽  
Critical Role ◽  
Point Of View ◽  
Information Flows ◽  
Mass Customisation ◽  
Different Types ◽  
Type Information ◽  
Different Levels

Concentrating on the role of supply chain decoupling point, this chapter introduces different levels of customisation and mass operations and three types of mass customisation. It argues that in each mass customisation type, information systems which are upstream and downstream of the decoupling point can be varied. Consequently, information flows in different types of mass customisation have been examined. This analysis is an endeavour to organise mass customisation information systems across the supply chain, while it can be a useful structure for future researches in this area as well.

scholarly journals Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Wei Ni ◽  
Zirong Chen ◽  
Xin Zhou ◽  
Rongqiang Yang ◽  
Mu Yu ◽  
...  
Keyword(s):  
Notch Signaling ◽  
Mucoepidermoid Carcinoma ◽  
Critical Role ◽  
Chromosomal Translocation ◽  
Egfr Signaling ◽  
Novel Approach ◽  
Poor Treatment

AbstractMucoepidermoid carcinoma (MEC) is the most common type of salivary gland cancers and patients with advanced, metastatic, and recurrent MECs have limited therapeutic options and poor treatment outcomes. MEC is commonly associated with a chromosomal translocation t(11;19) (q14-21;p12-13) that encodes the CRTC1-MAML2 oncogenic fusion. The CRTC1-MAML2 fusion is required for MEC growth in part through inducing autocrine AREG-EGFR signaling. Growing evidence suggests that MEC malignancy is maintained by cancer stem-like cells. In this study, we aimed to determine critical signaling for maintaining MEC stem-like cells and the effect of combined targeting of stem cell signaling and CRTC1-MAML2-induced EGFR signaling on blocking MEC growth. First, we evaluated the significance of Notch signaling in regulating MEC stem-like cells. Aberrantly activated Notch signaling was detected in human fusion-positive MEC cells. The inhibition of Notch signaling with genetic or pharmacological inhibitors reduced oncosphere formation and ALDH-bright population in vitro and blocked the growth of MEC xenografts in vivo. Next, we investigated the effect of co-targeting Notch signaling and EGFR signaling, and observed enhanced inhibition on MEC growth in vivo. Collectively, this study identified a critical role of Notch signaling in maintaining MEC stem-like cells and tumor growth, and revealed a novel approach of co-targeting Notch and EGFR signaling as a potential effective anti-MEC treatment.

scholarly journals Collaboration is the Key

2021 ◽  
Author(s):  
Elizabeth Greef
Keyword(s):  
Learning Communities ◽  
Critical Role ◽  
Collaborative Practice ◽  
Process Models ◽  
Teaching Staff ◽  
Relevant Research ◽  
Information Process ◽  
Micro Level ◽  
Set Up

What is the value and shape of collaborative practice for the teacher librarian in schools? This paper will look at definitions of collaborative practice, relevant research, the critical role of the teacher librarian, information process models and the underpinning pedagogy of learning communities, information literacy and constructivist learning. It will present a range of strategies at the macro level for developing opportunities for collaboration with teaching staff and library colleagues and at the micro level, strategies to enable the collaboration to occur in an effective and integrated way once avenues of communication and other forums have been set up.

scholarly journals Region-Based Global Reasoning Networks

2020 ◽  
Vol 34 (07) ◽  
pp. 12136-12143
Author(s):  
Chuanming Wang ◽  
Huiyuan Fu ◽  
Charles X. Ling ◽  
Peilun Du ◽  
Huadong Ma
Keyword(s):  
Critical Role ◽  
Aggregation Method ◽  
Long Distance ◽  
Fine Grained ◽  
Regional Features ◽  
Novel Approach ◽  
Visual Understanding ◽  
Region Aggregation ◽  
The Relationship

Global reasoning plays a significant role in many computer vision tasks which need to capture long-distance relationships. However, most current studies on global reasoning focus on exploring the relationship between pixels and ignore the critical role of the regions. In this paper, we propose an novel approach that explores the relationship between regions which have richer semantics than pixels. Specifically, we design a region aggregation method that can gather regional features automatically into a uniform shape, and adjust theirs positions adaptively for better alignment. To achieve the best performance of global reasoning, we propose various relationship exploration methods and apply them on the regional features. Our region-based global reasoning module, named ReGr, is end-to-end and can be inserted into existing visual understanding models without extra supervision. To evaluate our approach, we apply ReGr to fine-grained classification and action recognition benchmark tasks, and the experimental results demonstrate the effectiveness of our approach.

The Use of New Data Sources in Archival Accounting Research: Implications to Accounting Information Systems and Emerging Technologies

2021 ◽  
Author(s):  
Yu Cong ◽  
Hui Du
Keyword(s):  
Information Systems ◽  
Emerging Technologies ◽  
Empirical Studies ◽  
Critical Role ◽  
Accounting Information ◽  
Data Availability ◽  
Data Sources ◽  
Accounting Information Systems ◽  
General Business

We explore the connections from phenomena to new data and from data to theories. While starting with philosophical perspectives from positive economic theory to positive accounting theory, we emphasize the relevance and importance of new data sources to archival research in accounting and the implications to research in accounting information systems and emerging technologies. We present a number of studies in accounting that exemplify the critical role of data in the discovery of theories from phenomena. We argue that data in conventional empirical studies limit methodology to require assumptions and complex econometric treatments for general business settings. Therefore, recent development in "big data" and data analytics, particularly, the improved data availability from a variety of new sources have made strong research designs possible. We provide evidence that 88% of the JIS and 100% of the JETA empirical archival publications in the recent two years used new data sources.

Power, politics, and the institutionalisation of information systems for promoting digital transformation in the public sector: A case of the South African’s government digital transformation journey

2021 ◽  
pp. 1-18
Author(s):  
More Ickson Manda
Keyword(s):  
Information Systems ◽  
Public Sector ◽  
New Technologies ◽  
Critical Role ◽  
Digital Transformation ◽  
Power Dynamics ◽  
Power Politics ◽  
Holistic View ◽  
The Public

The institutionalisation of new technologies, information systems, norms, practices and other innovations for improving governance, planning, operational efficiency and service delivery in the public sector remain a challenge. Power dynamics, and politics have also been recognised as playing a critical role in the institutionalisation of information systems for promoting digital transformation of the public sector. This study used data collected through an extensive review of literature and empirical data from a case study of South Africa’s government digital transformation journey. The study explored power dynamics and the role of politics in the institutionalisation of reforms and deinstitutionalisation of institutionalised practices that constrain transformation in institutions. Power dynamics, and politics in institutions were found to have a significant bearing on the institutionalisation of reforms that include information systems in the digital transformation of government. The study found that the digital transformation of the public is more than the implementation technology and requires the holistic view of institutions as social, economic, and political structures.

scholarly journals Green infrastructure as a disease prevention and rehabilitation tool

2019 ◽  
Vol 28 (4) ◽  
pp. 682-689
Author(s):  
Tymon Dmochowski
Keyword(s):  
Disease Prevention ◽  
National Health ◽  
Economic Burden ◽  
Green Infrastructure ◽  
Physical Inactivity ◽  
Conventional Treatment ◽  
Critical Role ◽  
Public Spaces ◽  
Patient Treatment

This article tackles with the problem of preventing diseases caused by physical inactivity. It offers a brief review of deadliest diseases and defi nes critical role of green public spaces in their prevention. Article presents patient treatment costs, in contrast to the costs of organizing green public spaces, suggesting substantial relief from economic burden sustained by national health fund by offering green public spaces designed specifi cally for disease prevention instead of conventional treatment.

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