Spiritual Emergency

2022 ◽  
pp. 301-317
Author(s):  
Rajeev Kumar
Keyword(s):  
Human Body ◽  
Mindfulness Meditation ◽  
Endocrine System ◽  
Clinical Settings ◽  
Spiritual Emergency ◽  
Therapeutic Guidelines ◽  
Essential Components ◽  
Behavioral Manifestation ◽  
Spiritual Emergencies ◽  
Emergency Professionals

Mindfulness meditation has been proven efficient in treating many physical and psychological disorders. Mindfulness meditation techniques are also subjected to specific indications and contraindications. Scanning of gross body, thoughts, emotions, and memories are the essential components of any form of meditation. During those scannings, some unwanted memories and some unusual experiences are very much apparent. There are many energy points in the gross human body, which are correspondent to the endocrine system of the human body, known as Kundalini or Chakra. During meditation, those chakras are stimulated, and hidden energy is exploded; increased psychomotor activities manifest in the behaviors of the person. This behavioral manifestation is called a spiritual emergency. Professionals often confused this behavioral manifestation with psychotic illness. A spiritual emergency requires specific therapeutic management. Against this backdrop, this chapter attempts a review of research articles on spiritual emergencies and therapeutic guidelines to handle them in clinical settings.

The Endocrine System: Pituitary Gland

2017 ◽  
Author(s):  
Omer Doron ◽  
Jose E Cohen ◽  
Iddo Paldor
Keyword(s):  
Pituitary Gland ◽  
Human Body ◽  
Sella Turcica ◽  
Endocrine System ◽  
Portal System ◽  
Balance Growth ◽  
Sexual Drive ◽  
Pituitary Dysfunction ◽  
Physiologic Function ◽  
And Function

The pituitary gland is the main point where the neural and endocrine systems function in continuity, maintaining homeostasis of many functional elements of the human body. Located inside the sella turcica, it is separated from the rest of the central nervous system (CNS); however, it plays a crucial part in the regulation of the fundamental endocrine profile, inhibiting or promoting CNS signaling to the rest of the human body. Made up of two distinct tissue subtypes, this gland is fed by a complex vascular network, which enables communication beyond the blood-brain barrier. Lying in close proximity to both important neural and vascular structure, changes in gland size and function result in significant clinical impact. The pituitary gland controls many processes, among which are thermoregulation; metabolism and metabolic rate; glucose, solute, and water balance; growth and development; blood pressure; and sexual drive, pregnancy, childbearing, birth, and breast-feeding. The devastating effects of pituitary dysfunction underscore the importance of the pituitary gland in maintenance of the various functions that underlie normal everyday human activity. This review covers the basic aspects of pituitary gland development, anatomy, and physiologic function. This review contains 3 figures, and 38 references, Key words: adenohypophysis, neurohypophysis, pituitary-hypothalamic axis, pituitary portal system, sella turcica

The Endocrine System: Pituitary Gland

2017 ◽  
Author(s):  
Omer Doron ◽  
Jose E Cohen ◽  
Iddo Paldor
Keyword(s):  
Pituitary Gland ◽  
Human Body ◽  
Sella Turcica ◽  
Endocrine System ◽  
Portal System ◽  
Balance Growth ◽  
Sexual Drive ◽  
Pituitary Dysfunction ◽  
Physiologic Function ◽  
And Function

The pituitary gland is the main point where the neural and endocrine systems function in continuity, maintaining homeostasis of many functional elements of the human body. Located inside the sella turcica, it is separated from the rest of the central nervous system (CNS); however, it plays a crucial part in the regulation of the fundamental endocrine profile, inhibiting or promoting CNS signaling to the rest of the human body. Made up of two distinct tissue subtypes, this gland is fed by a complex vascular network, which enables communication beyond the blood-brain barrier. Lying in close proximity to both important neural and vascular structure, changes in gland size and function result in significant clinical impact. The pituitary gland controls many processes, among which are thermoregulation; metabolism and metabolic rate; glucose, solute, and water balance; growth and development; blood pressure; and sexual drive, pregnancy, childbearing, birth, and breast-feeding. The devastating effects of pituitary dysfunction underscore the importance of the pituitary gland in maintenance of the various functions that underlie normal everyday human activity. This review covers the basic aspects of pituitary gland development, anatomy, and physiologic function. This review contains 3 figures, and 38 references, Key words: adenohypophysis, neurohypophysis, pituitary-hypothalamic axis, pituitary portal system, sella turcica

Normal physiology of the endocrine system

2016 ◽  
Author(s):  
Simon Baudouin ◽  
Steve Ball
Keyword(s):  
Endocrine System ◽  
Cellular Level ◽  
Signal Transduction Pathways ◽  
Clinical Settings ◽  
Hormone Regulation ◽  
Functional Design ◽  
Hormone Action ◽  
Adaptive Responses ◽  
System P

The endocrine system describes an array of chemical signals (hormones). Working in concert with the nervous system, the endocrine system forms a complex neurohumoral network, communicating changes in the environment to facilitate adaptive responses and serving to integrate those responses in a coherent, coordinated manner. The endocrine system has inherent rhythmicity, which has important implications for the integration and coordination of metabolism, and how we measure endocrine signals in clinical settings. At a cellular level, hormone action is mediated through a series of discrete, but interacting signal transduction pathways. This chapter outlines a functional design approach to endocrinology; providing a framework covering the principles of hormone regulation and hormone action—critical for understanding the role of the endocrine system in physiology and pathophysiology.

Mental Illness through the Lens of Mindfulness

2020 ◽  
Author(s):  
Patricia Lynn Dobkin ◽  
Kaveh Monshat
Keyword(s):  
Mental Illness ◽  
Mindfulness Meditation ◽  
Well Being ◽  
The Self ◽  
Mindfulness Practice ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Middle Way ◽  
Western Psychology ◽  
Essential Components

The intention of this chapter is to re-envision mental illness within a paradigm that unites the biopsychosocial paradigm with a modern Buddhist spirituality, particularly associated with mindfulness. Emotion regulation, a balanced relationship with one’s self-concept, and social connection are usually regarded as essential components of well-being within both systems of thought. Western psychology and mindfulness practice have, at times, been seen to have fundamentally opposing aims: one to strengthen the self and the other to arrive at “no-self” or “emptiness.” This chapter purports that the two approaches may overlap and can be complementary both in their contribution to understanding the self and the regulation of emotions. Clinical narratives of depression, anxiety, obsessive-compulsive disorder, and psychosis are included to exemplify the application of a whole-person outlook to understand mental illness. While an orientation to well-being through a mindfulness perspective may be generally helpful, mindfulness meditation is not a panacea: for some patients, it may be contraindicated, applied in a modified format, or used alongside medication and/or psychotherapy. This chapter presents a “middle way” between the views of suffering that informs mindfulness practice and that which is drawn from psychology and psychiatry.

Inactivation of parathyroid hormone: perspectives of drug discovery to combating hyperparathyroidism

2021 ◽  
Vol 14 ◽  
Author(s):  
Amit Kumar ◽  
Jochen Balbach
Keyword(s):  
Parathyroid Hormone ◽  
Small Molecules ◽  
Human Body ◽  
Endocrine System ◽  
Calcium Deposition ◽  
Molecular Signaling ◽  
Internal Factors ◽  
Blood Calcium ◽  
N Terminus ◽  
G Protein Coupled

: Hormonal coordination is tightly regulated within the human body and thus regulates human physiology. The parathyroid hormone (PTH), a member of the endocrine system, regulates the calcium and phosphate level within the human body. Under non-physiological conditions, PTH levels get upregulated (hyperparathyroidism) or downregulated (hypoparathyroidism) due to external or internal factors. In the case of hyperparathyroidism, elevated PTH stimulates cellular receptors present in the bones, kidneys, and intestines to increase the blood calcium level, leading to calcium deposition. This eventually causes various symptoms including kidney stones. Currently, there is no known medication that directly targets PTH in order to suppress its function. Therefore, it is of great interest to find novel small molecules or any other means that can modulate PTH function. The molecular signaling of PTH starts by binding of its N-terminus to the G-protein coupled PTH1/2 receptor. Therefore, any intervention that affects the N-terminus of PTH could be a lead candidate for treating hyperparathyroidism. As a proof-of-concept, there are various possibilities to inhibit molecular PTH function by (i) a small molecule, (ii) N-terminal PTH phosphorylation, (iii) fibril formation and (iv) residue-specific mutations. These modifications put PTH into an inactive state, which will be discussed in detail in this review article. We anticipate that exploring small molecules or other means that affect the N-terminus of PTH could be lead candidates in combating hyperparathyroidism.

scholarly journals Ageing and vitamin D deficiency: effects on calcium homeostasis and considerations for vitamin D supplementation

2009 ◽  
Vol 101 (11) ◽  
pp. 1597-1606 ◽  
Author(s):  
Christian Oudshoorn ◽  
Tischa J. M. van der Cammen ◽  
Marion E. T. McMurdo ◽  
Johannes P. T. M. van Leeuwen ◽  
Edgar M. Colin
Keyword(s):  
Vitamin D ◽  
Vitamin D Receptor ◽  
Calcium Homeostasis ◽  
Human Body ◽  
Steroid Hormone ◽  
Endocrine System ◽  
Vitamin D Supplementation ◽  
Multiple Systems ◽  
Almost All ◽  
Ca Homeostasis

Vitamin D is a fat-soluble, seco-steroid hormone. In man, the vitamin D receptor is expressed in almost all tissues, enabling effects in multiple systems of the human body. These effects can be endocrine, paracrine and autocrine. The present review summarises the effects of ageing on the vitamin D endocrine system and on Ca homeostasis. Furthermore, consequences for vitamin D supplementation are discussed.

scholarly journals Hospital pharmacists’ experiences of participating in a partnered pharmacist medication charting credentialing program: a qualitative study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hannah Beks ◽  
Kevin Mc Namara ◽  
Elizabeth Manias ◽  
Andrew Dalton ◽  
Erica Tong ◽  
...  
Keyword(s):  
Medical Officer ◽  
Hospital Setting ◽  
Qualitative Evaluation ◽  
Clinical Settings ◽  
Medication History ◽  
Local Adaptations ◽  
Policies And Procedures ◽  
Essential Components ◽  
Key Issues ◽  
Implementation Data

Abstract Background Medication-related errors are one of the most frequently reported incidents in hospitals. With the aim of reducing the medication error rate, a Partnered Pharmacist Medication Charting (PPMC) model was trialled in seven Australian hospitals from 2016 to 2017. Participating pharmacists completed a credentialing program to equip them with skills to participate in the trial as a medication-charting pharmacist. Skills included obtaining a comprehensive medication history to chart pre-admission medications in collaboration with an admitting medical officer. The program involved both theoretical and practical components to assess the competency of pharmacists. Methods A qualitative evaluation of the multi-site PPMC implementation trial was undertaken. Pharmacists and key informants involved in the trial participated in an interview or focus group session to share their experiences and attitudes regarding the PPMC credentialing program. An interview schedule was used to guide sessions. Transcripts were analysed using a pragmatic inductive-deductive thematic approach. Results A total of 125 participants were involved in interviews or focus groups during early and late implementation data collection periods. Three themes pertaining to the PPMC credentialing program were identified: (1) credentialing as an upskilling opportunity, (2) identifying the essential components of credentialing, and (3) implementing and sustaining the PPMC credentialing program. Conclusions The PPMC credentialing program provided pharmacists with an opportunity to expand their scope of practice and consolidate clinical knowledge. Local adaptations to the PPMC credentialing program enabled pharmacists to meet the varying needs and capacities of hospitals, including the policies and procedures of different clinical settings. These findings highlight key issues to consider when implementation a credentialing program for pharmacists in the hospital setting.

The Endocrine System: Pituitary Gland

2017 ◽  
Author(s):  
Omer Doron ◽  
Jose E Cohen ◽  
Iddo Paldor
Keyword(s):  
Pituitary Gland ◽  
Human Body ◽  
Sella Turcica ◽  
Endocrine System ◽  
Portal System ◽  
Balance Growth ◽  
Sexual Drive ◽  
Pituitary Dysfunction ◽  
Physiologic Function ◽  
And Function

The pituitary gland is the main point where the neural and endocrine systems function in continuity, maintaining homeostasis of many functional elements of the human body. Located inside the sella turcica, it is separated from the rest of the central nervous system (CNS); however, it plays a crucial part in the regulation of the fundamental endocrine profile, inhibiting or promoting CNS signaling to the rest of the human body. Made up of two distinct tissue subtypes, this gland is fed by a complex vascular network, which enables communication beyond the blood-brain barrier. Lying in close proximity to both important neural and vascular structure, changes in gland size and function result in significant clinical impact. The pituitary gland controls many processes, among which are thermoregulation; metabolism and metabolic rate; glucose, solute, and water balance; growth and development; blood pressure; and sexual drive, pregnancy, childbearing, birth, and breast-feeding. The devastating effects of pituitary dysfunction underscore the importance of the pituitary gland in maintenance of the various functions that underlie normal everyday human activity. This review covers the basic aspects of pituitary gland development, anatomy, and physiologic function. This review contains 3 figures, and 38 references, Key words: adenohypophysis, neurohypophysis, pituitary-hypothalamic axis, pituitary portal system, sella turcica

scholarly journals Physiological Importance of Hydrogen Sulfide: Emerging Potent Neuroprotector and Neuromodulator

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Sandesh Panthi ◽  
Hyung-Joo Chung ◽  
Junyang Jung ◽  
Na Young Jeong
Keyword(s):  
Hydrogen Sulfide ◽  
Human Body ◽  
Defense Mechanism ◽  
Peripheral Nerve Regeneration ◽  
Endocrine System ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Beneficial Effects ◽  
Physiological Importance ◽  
Wide Range

Hydrogen sulfide (H2S) is an emerging neuromodulator that is considered to be a gasotransmitter similar to nitrogen oxide (NO) and carbon monoxide (CO). H2S exerts universal cytoprotective effects and acts as a defense mechanism in organisms ranging from bacteria to mammals. It is produced by the enzymes cystathionineβ-synthase (CBS), cystathionineϒ-lyase (CSE), 3-mercaptopyruvate sulfurtransferase (MST), and D-amino acid oxidase (DAO), which are also involved in tissue-specific biochemical pathways for H2S production in the human body. H2S exerts a wide range of pathological and physiological functions in the human body, from endocrine system and cellular longevity to hepatic protection and kidney function. Previous studies have shown that H2S plays important roles in peripheral nerve regeneration and degeneration and has significant value during Schwann cell dedifferentiation and proliferation but it is also associated with axonal degradation and the remyelination of Schwann cells. To date, physiological and toxic levels of H2S in the human body remain unclear and most of the mechanisms of action underlying the effects of H2S have yet to be fully elucidated. The primary purpose of this review was to provide an overview of the role of H2S in the human body and to describe its beneficial effects.

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