The Black Box Myth

Author(s):  
Abraham Rudnick

Artificial intelligence (AI) and its correlates, such as machine and deep learning, are changing health care, where complex matters such as comoribidity call for dynamic decision-making. Yet, some people argue for extreme caution, referring to AI and its correlates as a black box. This brief article uses philosophy and science to address the black box argument about knowledge as a myth, concluding that this argument is misleading as it ignores a fundamental tenet of science, i.e., that no empirical knowledge is certain, and that scientific facts – as well as methods – often change. Instead, control of the technology of AI and its correlates has to be addressed to mitigate such unexpected negative consequences.

2020 ◽  
Author(s):  
Sana Syed ◽  
Lubaina Ehsan ◽  
Aman Shrivastava ◽  
Saurav Sengupta ◽  
Marium Khan ◽  
...  

Objectives: Striking histopathological overlap between distinct but related conditions poses a significant disease diagnostic challenge. There is a major clinical need to develop computational methods enabling clinicians to translate heterogeneous biomedical images into accurate and quantitative diagnostics. This need is particularly salient with small bowel enteropathies; Environmental Enteropathy (EE) and Celiac Disease (CD). We built upon our preliminary analysis by developing an artificial intelligence (AI)-based image analysis platform utilizing deep learning convolutional neural networks (CNNs) for these enteropathies. Methods: Data for secondary analysis was obtained from three primary studies at different sites. The image analysis platform for EE and CD was developed using convolutional neural networks (CNNs: ResNet and custom Shallow CNN). Gradient-weighted Class Activation Mappings (Grad-CAMs) were used to visualize the decision making process of the models. A team of medical experts simultaneously reviewed the stain color normalized images done for bias reduction and Grad-CAM visualizations to confirm structural preservation and biological relevance, respectively. Results: 461 high-resolution biopsy images from 150 children were acquired. Median age (interquartile range) was 37.5 (19.0 to 121.5) months with a roughly equal sex distribution; 77 males (51.3%). ResNet50 and Shallow CNN demonstrated 98% and 96% case-detection accuracy, respectively, which increased to 98.3% with an ensemble. Grad-CAMs demonstrated ability of the models to learn distinct microscopic morphological features. Conclusion: Our AI-based image analysis platform demonstrated high classification accuracy for small bowel enteropathies which was capable of identifying biologically relevant microscopic features, emulating human pathologist decision making process, performing in the case of suboptimal computational environment, and being modified for improving disease classification accuracy. Grad-CAMs that were employed illuminated the otherwise black box of deep learning in medicine, allowing for increased physician confidence in adopting these new technologies in clinical practice.


2020 ◽  
Vol 2 ◽  
pp. 58-61 ◽  
Author(s):  
Syed Junaid ◽  
Asad Saeed ◽  
Zeili Yang ◽  
Thomas Micic ◽  
Rajesh Botchu

The advances in deep learning algorithms, exponential computing power, and availability of digital patient data like never before have led to the wave of interest and investment in artificial intelligence in health care. No radiology conference is complete without a substantial dedication to AI. Many radiology departments are keen to get involved but are unsure of where and how to begin. This short article provides a simple road map to aid departments to get involved with the technology, demystify key concepts, and pique an interest in the field. We have broken down the journey into seven steps; problem, team, data, kit, neural network, validation, and governance.


2020 ◽  
Vol 114 ◽  
pp. 242-245
Author(s):  
Jootaek Lee

The term, Artificial Intelligence (AI), has changed since it was first coined by John MacCarthy in 1956. AI, believed to have been created with Kurt Gödel's unprovable computational statements in 1931, is now called deep learning or machine learning. AI is defined as a computer machine with the ability to make predictions about the future and solve complex tasks, using algorithms. The AI algorithms are enhanced and become effective with big data capturing the present and the past while still necessarily reflecting human biases into models and equations. AI is also capable of making choices like humans, mirroring human reasoning. AI can help robots to efficiently repeat the same labor intensive procedures in factories and can analyze historic and present data efficiently through deep learning, natural language processing, and anomaly detection. Thus, AI covers a spectrum of augmented intelligence relating to prediction, autonomous intelligence relating to decision making, automated intelligence for labor robots, and assisted intelligence for data analysis.


2021 ◽  
Vol 20 ◽  
pp. 153303382110163
Author(s):  
Danju Huang ◽  
Han Bai ◽  
Li Wang ◽  
Yu Hou ◽  
Lan Li ◽  
...  

With the massive use of computers, the growth and explosion of data has greatly promoted the development of artificial intelligence (AI). The rise of deep learning (DL) algorithms, such as convolutional neural networks (CNN), has provided radiation oncologists with many promising tools that can simplify the complex radiotherapy process in the clinical work of radiation oncology, improve the accuracy and objectivity of diagnosis, and reduce the workload, thus enabling clinicians to spend more time on advanced decision-making tasks. As the development of DL gets closer to clinical practice, radiation oncologists will need to be more familiar with its principles to properly evaluate and use this powerful tool. In this paper, we explain the development and basic concepts of AI and discuss its application in radiation oncology based on different task categories of DL algorithms. This work clarifies the possibility of further development of DL in radiation oncology.


2021 ◽  
Author(s):  
Yew Kee Wong

Deep learning is a type of machine learning that trains a computer to perform human-like tasks, such as recognizing speech, identifying images or making predictions. Instead of organizing data to run through predefined equations, deep learning sets up basic parameters about the data and trains the computer to learn on its own by recognizing patterns using many layers of processing. This paper aims to illustrate some of the different deep learning algorithms and methods which can be applied to artificial intelligence analysis, as well as the opportunities provided by the application in various decision making domains.


Author(s):  
Usef Faghihi ◽  
Sioui Maldonado-Bouchard ◽  
Mario Incayawar

Today, deep learning (DL) algorithms are intertwined with our daily life. This subdomain of artificial intelligence (AI) technology is used to unlock your phone by only detecting your face, find the best path from work to your home or vice versa, or detect anomalies in the human cells taken for lab tests. Yet, although AI technology is helping in many fields, whether it has done so in the medical field is debatable. DL lacks reasoning; it is unable to determine the causes of events. This is especially crucial when it comes to the health care sector. At this point, computers cannot help physicians with their duties. On the contrary, they are the cause of burnout in more than half of physicians in United States. One of the causes of burnout repeatedly pointed out by physicians is the digitalization of medicine. This chapter presents some of the AI approaches that could help physicians. It also discusses the current limitations and dangers inherent to many of today’s state-of-the-art AI systems. The authors provide some ideas about the future of AI in pain medicine and psychiatry.


2018 ◽  
Vol 1 (1) ◽  
pp. 181-205 ◽  
Author(s):  
Pierre Baldi

Since the 1980s, deep learning and biomedical data have been coevolving and feeding each other. The breadth, complexity, and rapidly expanding size of biomedical data have stimulated the development of novel deep learning methods, and application of these methods to biomedical data have led to scientific discoveries and practical solutions. This overview provides technical and historical pointers to the field, and surveys current applications of deep learning to biomedical data organized around five subareas, roughly of increasing spatial scale: chemoinformatics, proteomics, genomics and transcriptomics, biomedical imaging, and health care. The black box problem of deep learning methods is also briefly discussed.


Computation ◽  
2019 ◽  
Vol 7 (2) ◽  
pp. 25 ◽  
Author(s):  
Abhaya Kumar Sahoo ◽  
Chittaranjan Pradhan ◽  
Rabindra Kumar Barik ◽  
Harishchandra Dubey

In today’s digital world healthcare is one core area of the medical domain. A healthcare system is required to analyze a large amount of patient data which helps to derive insights and assist the prediction of diseases. This system should be intelligent in order to predict a health condition by analyzing a patient’s lifestyle, physical health records and social activities. The health recommender system (HRS) is becoming an important platform for healthcare services. In this context, health intelligent systems have become indispensable tools in decision making processes in the healthcare sector. Their main objective is to ensure the availability of the valuable information at the right time by ensuring information quality, trustworthiness, authentication and privacy concerns. As people use social networks to understand their health condition, so the health recommender system is very important to derive outcomes such as recommending diagnoses, health insurance, clinical pathway-based treatment methods and alternative medicines based on the patient’s health profile. Recent research which targets the utilization of large volumes of medical data while combining multimodal data from disparate sources is discussed which reduces the workload and cost in health care. In the healthcare sector, big data analytics using recommender systems have an important role in terms of decision-making processes with respect to a patient’s health. This paper gives a proposed intelligent HRS using Restricted Boltzmann Machine (RBM)-Convolutional Neural Network (CNN) deep learning method, which provides an insight into how big data analytics can be used for the implementation of an effective health recommender engine, and illustrates an opportunity for the health care industry to transition from a traditional scenario to a more personalized paradigm in a tele-health environment. By considering Root Square Mean Error (RSME) and Mean Absolute Error (MAE) values, the proposed deep learning method (RBM-CNN) presents fewer errors compared to other approaches.


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