scholarly journals Antimicrobial activity of the edible mushroom Pleurotus eryngii (DC.) Quél grown in liquid medium

2021 ◽  
Vol 43 ◽  
pp. e58474
Author(s):  
Cleudiane Pereira de Andrade ◽  
Aldiane Passos de Oliveira ◽  
Victor Matheus Cabral Vieira ◽  
Bruna Ketley Paes Frazão ◽  
Raiana Silveira Gurgel ◽  
...  

Edible mushrooms have a number of medicinal properties and this study aimed to investigate the antimicrobial activity of Pleurotus eryngii DPUA1816 in metabolic broths after being grown in submerged cultivation. Mycelial fragments of pure P. eryngii culture was inoculated in sweet potato culture medium and incubated at 150 rpm for 15 days at 25°C. Pleurotus eryngii was also cultivated for 18 days under the same conditions, the mycelial biomass was separated by filtration for quantification. The supernatant was used in the diffusion test in agar and performed against Escherichia coli CCCD-E005, Staphylococcus aureus CCCD-S009, Pseudomonas aeruginosa CCCD-P004, Candida albicans CCCD-CC001, Candida parapsilosis CCCD-CC004 and Candida tropicalis CCCD-CC002. The samples showed no inhibitory activity against bacteria, however they showed some activity against C. albicans (12.17 mm), C. parapsilosis (27.67 mm) and C. tropicalis (13.67 mm). After being cultivated for 18 days, P. eryngii was able to inhibit all yeasts after 12 days of culture, with an inhibition halo of 29.33 mm at 16 days against C. parapsilosis. This study demonstrates the antifungal potential filtered liquids from P. eryngii cultivated in purple-skinned sweet potato culture medium, which suggests the possibility of the use of this species by the pharmaceutical industry as a natural source of biological action.

2020 ◽  
Vol 12 (1) ◽  
pp. 128-132
Author(s):  
I.A. Raubilu ◽  
U. Isah ◽  
M.A. Ahmad

Moringa oleifera Lam. (Family Moringaceae) is well – known for its various medicinal properties. It grows wild in the tropical and subtropical areas of Asia, Africa and the Middle East. In Nigeria, Moringa oleifera trees are planted at a large scale especially in the northern part of the country. It has been widely used in the treatment of certain diseases as a traditional medicinal herb. Antimicrobial activity is the most studied property of Moringa oleifera. Many studies have shown that nearly all types of Moringa oleifera tissues exhibit antimicrobial activity including antibacterial, antifungal, antiviral and anti parasitic property. This review describes progress on research conducted to understand the antimicrobial activity of Moringa oleifera and discusses the potential use of Moringa oleifera in the control of pathogenic microbes. Key words: Antimicrobial activity; Moringa oleifera; pathogenic microbes, control.  


Plants ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 211 ◽  
Author(s):  
Paco Noriega ◽  
José Ballesteros ◽  
Alejandra De la Cruz ◽  
Tatiana Veloz

This study evaluates the antimicrobial and antifungal potential of the essential oil extracted from a species located in the Andes of Ecuador, Piper barbatum Kunth, known as “cordoncillo” or “allupa”, used by the Quichua people as an antibacterial plant for washing female genitalia in cases of infection. The most abundant molecules in the essential oil were: α- phellandrene (43.16%), limonene (7.04%); some oxygenated sesquiterpenes such as: trans-sesquisabinene hydrate (8.23%), elemol (7.21%) and others. The evaluation of antimicrobial activity showed activity in all the strains analyzed; however, those in which MIC values are considered to be very strong (less than 500 µg/mL) are: Staphylococcus aureus 264 µg/mL, Streptococcus mutans 132 µg/mL, Candida albicans 132 µg/mL and Candida tropicalis 264 µg/mL. Antimicrobial bioautography defines which molecules are responsible for the activity; thus, it was possible to establish the chromatographic regions of = 0.02 and Rf = 0.04, as those with active molecules. It was established that 4 hydroxylated sesquiterpene molecules are involved: elemol (7.21%), trans-sesquisabinene hydrate (8.23%), β–eudesmol (3.49%) and 10-epi-γ-eudesmol (1.07%); the last two being the most active. The aim of this manuscript is to analyze both the ancestral knowledge of the Quichua people of Ecuador, and the chemical-biodiversity of the Andean forest ecosystem, in order to provide new raw materials of pharmaceutical interest.


2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Carlos E. Salas ◽  
Jesus A. Badillo-Corona ◽  
Guadalupe Ramírez-Sotelo ◽  
Carmen Oliver-Salvador

Bioactive peptides are part of an innate response elicited by most living forms. In plants, they are produced ubiquitously in roots, seeds, flowers, stems, and leaves, highlighting their physiological importance. While most of the bioactive peptides produced in plants possess microbicide properties, there is evidence that they are also involved in cellular signaling. Structurally, there is an overall similarity when comparing them with those derived from animal or insect sources. The biological action of bioactive peptides initiates with the binding to the target membrane followed in most cases by membrane permeabilization and rupture. Here we present an overview of what is currently known about bioactive peptides from plants, focusing on their antimicrobial activity and their role in the plant signaling network and offering perspectives on their potential application.


2007 ◽  
Vol 62 (12) ◽  
pp. 1585-1589 ◽  
Author(s):  
Yoshihito Shiono ◽  
Fuminori Hiramatsu ◽  
Tetsuya Murayama ◽  
Takuya Koseki ◽  
Takayuki Funakoshi ◽  
...  

Two novel drimane sesquiterpenoids, strobilactones A (3) and B (4), were isolated fromthe organic extract of a liquid culture of Strobilurus ohshimae. The structures of 3 and 4 were determined by spectroscopic methods. Compounds 3 and 4 exhibit cell growth inhibitory activities against cultured COLO 201 cells. Compound 4 also shows antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa.


2013 ◽  
Vol 138 (2-3) ◽  
pp. 1557-1563 ◽  
Author(s):  
K.K. Mishra ◽  
R.S. Pal ◽  
R. ArunKumar ◽  
C. Chandrashekara ◽  
S.K. Jain ◽  
...  

2020 ◽  
Author(s):  
Ekaterina A. Kukushkina ◽  
Maria Chiara Sportelli ◽  
Nicoletta Ditaranto ◽  
Rosaria Anna Picca ◽  
Nicola Cioffi

<p>Chitosan (CS), a natural non-toxic polysaccharide, shows intrinsic antimicrobial activity against a wide range of pathogens. CS and CS-based biomaterials can be effective additives in food and medicine-related industries to inhibit growth of pathogens. The application of inorganic nanophases, such as metal and metal oxide nanoparticles, has received attention due to their broad and pronounced antimicrobial activity. Upon combination with CS, which can act as stabilizer, with active inorganic nanophases, robust synergistic nanoantimicrobial (NAM) systems can be produced. These hybrid NAMs offer an alternative strategy to fight antimicrobial resistance and overcome limitations of conventional antibiotics. Bioactive ZnO, Cu and Ag nanophases produced by green electrochemical approach [Nanomaterials, 10(3) (2020), 473] and laser ablation in solution [(Coll. Surf. A, 559 (2018), 148-158), (Food packaging shelf, 22 (2019), 1000422)] can be combined with antimicrobial CS to develop synergistic antimicrobial nanohybrids with amplified biological action. CS-based NAMs were preliminary characterized by electron microscopies and spectroscopic techniques. Hybrid NAMs may find application in the control and inhibition of biofilm growth.</p> <p>Acknowledgements<br />Financial support is acknowledged from European Union’s 2020 research and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 813439</p>


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