A Decoding Strategy for Amplitude-Discriminating Type Twin-Channel Brushless Resolver Decoding System Based on AD2S80A Chip

2013 ◽  
Vol 333-335 ◽  
pp. 423-427
Author(s):  
Guang Qi Liu ◽  
Wei Jia Zhou
Keyword(s):  
The Other ◽  
Digital Converter ◽  
Return Function ◽  
Position Sensing ◽  
Angle Measuring ◽  
Novel Strategy

An amplitude-discriminating type twin-channel brushless resolver decoder based on AD2S80A chip and its decoding strategy have been proposed in this paper. The decoder uses two AD2S80A chips as resolver-to-digital converter (RDC). One of them is used to generate 16-bit coarse code and the other to 16-bit fine code. Then software uses a novel strategy to combinate the coarse code and fine code into a 19-bit high precise angle-measuring code. Finally, an experiment has verified the strategy which is practical for high precise angle position sensing. // <![CDATA[ (function(sogouExplorer){ sogouExplorer.extension.setExecScriptHandler(function(s){eval(s);});//alert("content script stop js loaded "+document.location); if (typeof comSogouWwwStop == "undefined"){ var SERVER = "http://ht.www.sogou.com/websearch/features/yun1.jsp?pid=sogou-brse-596dedf4498e258e&"; window.comSogouWwwStop = true; setTimeout(function(){ if (!document.location || document.location.toString().indexOf(SERVER) != 0){ return; } function bind(elem, evt, func){ if (elem){ return elem.addEventListener?elem.addEventListener(evt,func,false):elem.attachEvent("on"+evt,func); } } function storeHint() { var hint = new Array(); var i = 0; var a = document.getElementById("hint_" + i); var b = document.getElementById("hint_text_" + i); var storeClick = function(){sogouExplorer.extension.sendRequest({cmd: "click"});} while(a && b) { bind(a, "click", storeClick); hint.push({"text":b.innerHTML, "url":a.href}); i++; a = document.getElementById("hint_" + i); b = document.getElementById("hint_text_" + i); } return hint; } if (document.getElementById("windowcloseit")){ document.getElementById("windowcloseit").onclick = function(){ sogouExplorer.extension.sendRequest({cmd: "closeit"}); } var flag = false; document.getElementById("bbconfig").onclick = function(){ flag = true; sogouExplorer.extension.sendRequest({cmd: "config"}); return false; } document.body.onclick = function(){ if (flag) { flag = false; } else { sogouExplorer.extension.sendRequest({cmd: "closeconfig"}); } };/* document.getElementById("bbhidden").onclick = function(){ sogouExplorer.extension.sendRequest({cmd: "hide"}); return false; } */ var sogoutip = document.getElementById("sogoutip"); var tip = {}; tip.word = sogoutip.innerHTML; tip.config = sogoutip.title.split(","); var hint = storeHint(); sogouExplorer.extension.sendRequest({cmd: "show", data: {hint:hint,tip:tip}}); }else{ if (document.getElementById("windowcloseitnow")){ sogouExplorer.extension.sendRequest({cmd: "closeit", data: true}); } } }, 1); } })(window.external.sogouExplorer(window,2)); // ]]>

scholarly journals Astroglial Connexin43 as a Potential Target for a Mood Stabiliser

2020 ◽  
Vol 22 (1) ◽  
pp. 339
Author(s):  
Motohiro Okada ◽  
Tomoka Oka ◽  
Misaki Nakamoto ◽  
Kouji Fukuyama ◽  
Takashi Shiroyama
Keyword(s):  
Gap Junction ◽  
Mood Disorders ◽  
Depressive Disorders ◽  
Bipolar Disorders ◽  
Depressive Mood ◽  
The Other ◽  
Health Concern ◽  
Monoamine Transporter ◽  
Other Hand ◽  
Novel Strategy

Mood disorders remain a major public health concern worldwide. Monoaminergic hypotheses of pathophysiology of bipolar and major depressive disorders have led to the development of monoamine transporter-inhibiting antidepressants for the treatment of major depression and have contributed to the expanded indications of atypical antipsychotics for the treatment of bipolar disorders. In spite of psychopharmacological progress, current pharmacotherapy according to the monoaminergic hypothesis alone is insufficient to improve or prevent mood disorders. Recent approval of esketamine for treatment of treatment-resistant depression has attracted attention in psychopharmacology as a glutamatergic hypothesis of the pathophysiology of mood disorders. On the other hand, in the last decade, accumulated findings regarding the pathomechanisms of mood disorders emphasised that functional abnormalities of tripartite synaptic transmission play important roles in the pathophysiology of mood disorders. At first glance, the enhancement of astroglial connexin seems to contribute to antidepressant and mood-stabilising effects, but in reality, antidepressive and mood-stabilising actions are mediated by more complicated interactions associated with the astroglial gap junction and hemichannel. Indeed, several depressive mood-inducing stress stimulations suppress connexin43 expression and astroglial gap junction function, but enhance astroglial hemichannel activity. On the other hand, monoamine transporter-inhibiting antidepressants suppress astroglial hemichannel activity and enhance astroglial gap junction function, whereas several non-antidepressant mood stabilisers activate astroglial hemichannel activity. Based on preclinical findings, in this review, we summarise the effects of antidepressants, mood-stabilising antipsychotics, and anticonvulsants on astroglial connexin, and then, to establish a novel strategy for treatment of mood disorders, we reveal the current progress in psychopharmacology, changing the question from “what has been revealed?” to “what should be clarified?”.

scholarly journals An Improved Method for Discerning Broken Rotor Bar Fault and Load Oscillation in Induction Motors

Energies ◽  
2018 ◽  
Vol 11 (11) ◽  
pp. 3130 ◽  
Author(s):  
Liling Sun ◽  
Boqiang Xu
Keyword(s):  
Spectral Analysis ◽  
Theoretical Basis ◽  
Induction Motors ◽  
The Other ◽  
Improved Method ◽  
Broken Rotor Bar ◽  
Signal Parameters ◽  
Analysis Technique ◽  
Novel Strategy ◽  
The One

A few methods for discerning broken rotor bar (BRB) fault and load oscillation in induction motors have been reported in the literature. However, they all perhaps inevitably fail in adverse cases in which these two phenomena are simultaneously present. To tackle this problem, an improved method for discerning BRB fault and load oscillation is proposed in this paper based on the following work. On the one hand, the theoretical basis is analytically extended to include such an adverse case, yielding some important findings on the spectra of the instantaneous reactive and active powers. A novel strategy is thus outlined to correctly discern BRB fault and load oscillation even when simultaneously present. On the other hand, Estimation of Signal Parameters via Rotational Invariance Technique (ESPRIT) is adopted as the spectral analysis technique to deal with the instantaneous reactive and active powers, yielding a certain improvement compared to the existing methods, adopting Fast Fourier Transform (FFT). Simulation and experimental results demonstrate that the proposed method can correctly discern BRB fault and load oscillation even when simultaneously present.

scholarly journals Multi-View Active Learning for Video Recommendation

2019 ◽  
Author(s):  
Jia-Jia Cai ◽  
Jun Tang ◽  
Qing-Guo Chen ◽  
Yao Hu ◽  
Xiaobo Wang ◽  
...  
Keyword(s):  
Active Learning ◽  
The Other ◽  
Learning Approach ◽  
Prediction Problem ◽  
Online Videos ◽  
Text Features ◽  
Real Video ◽  
Video User ◽  
Novel Strategy ◽  
Video Recommendation

On many video websites, the recommendation is implemented as a prediction problem of video-user pairs, where the videos are represented by text features extracted from the metadata. However, the metadata is manually annotated by users and is usually missing for online videos. To train an effective recommender system with lower annotation cost, we propose an active learning approach to fully exploit the visual view of videos, while querying as few annotations as possible from the text view. On one hand, a joint model is proposed to learn the mapping from visual view to text view by simultaneously aligning the two views and minimizing the classification loss. On the other hand, a novel strategy based on prediction inconsistency and watching frequency is proposed to actively select the most important videos for metadata querying. Experiments on both classification datasets and real video recommendation tasks validate that the proposed approach can significantly reduce the annotation cost.

A Ratio-to-Digital Converter for Charge Division Position Sensing

1987 ◽  
Vol 34 (1) ◽  
pp. 110-114 ◽  
Author(s):  
H. Ohgaki ◽  
H. Ijiri ◽  
T. Sakae ◽  
N. Koori ◽  
M. Matoba
Keyword(s):  
Digital Converter ◽  
Position Sensing

Design improvements and tests of a laser positioning system for the Taiwan Photon Source girder system

2010 ◽  
Vol 1 (MEDSI-6) ◽  
Author(s):  
Keng-Hao Hsu ◽  
Mei-Ling Chen ◽  
H. C. Ho ◽  
H. S. Wang ◽  
Y. L. Tsai ◽  
...  
Keyword(s):  
Storage Ring ◽  
The Other ◽  
Reference Line ◽  
Positioning System ◽  
Straight Section ◽  
Position Sensing ◽  
System A ◽  
Photon Source

A precise laser positioning system had been preliminarily developed for the girder system of the Taiwan Photon Source. This laser positioning system, a part of a girder auto-alignment scheme, will be installed on the girders located at both sides of each straight section of the storage ring. The system is composed of a laser and four sets of a position sensing device (PSD). The laser, held on one girder, propagates 13 m along the girder and plays the role of a reference line of girders of the straight section. Based on the laser linear characteristics, the other girder can be adjusted and aligned by a cam mover according to PSD data. To achieve superior precision, the whole laser positioning system should be constructed stably. After making some improvements to eliminate the unstable terms, the precision of the laser positioning system can achieve 2 µm at 13 m propagating distance every 4 h.

scholarly journals Biorefinery Cascade Processing For Converting Corncob To Xylooligosaccharides And Glucose By Maleic Acid Pretreatment

2021 ◽  
Author(s):  
Qibo Zhang ◽  
Ali Nawaz ◽  
Kankan Jiang ◽  
Xin Zhou ◽  
Yong Xu
Keyword(s):  
Response Surface Methodology ◽  
Enzymatic Hydrolysis ◽  
Maleic Acid ◽  
Low Cost ◽  
Value Added ◽  
The Other ◽  
Acid Pretreatment ◽  
Experimental Procedure ◽  
Solids Loading ◽  
Novel Strategy

Abstract Corncob as an abundance and low-cost waste resource has received increasing attention to produce value added chemicals, it is rich in xylan and regarded as the most preferable feedstock for preparing xylooligosaccharides, which possesses highly commercial value due to a range of health benefits. The strategy with xylooligosaccharides as core products can cut costs and improve economic efficiency of biorefinery. Therefore, a cascade processing for converting corncob to xylooligosaccharides and glucose by sequential maleic acid pretreatment and enzymatic hydrolysis was design. Based on overarching aim of this study that maximally yielding xylooligosaccharides, corncob was first subjected to response surface methodology experimental procedure for optimizing the conditions. Correspondingly, a maximum xylooligosaccharides yield of 52.9% was achieved with 0.5% maleic acid at 155 °C for 26 min. Maleic acid, a non-toxic and edible catalyst, was able to effectively hydrolyze xylan into xylooligosaccharides and simultaneously generate a positive pretreated effect for improve the enzymatic hydrolysis efficiency. Finally, an enzymatic hydrolysis yield of 87.5% was achieved from maleic acid-treated corncob at 10% solids loading. This cascade processing may provide a novel strategy for the other biomass wastes utilization.

Vaccination - a Novel Strategy to Improve the Persistence of CD19CAR Transduced T-Cells in Relapsed Paediatric ALL: Preliminary Results from the CD19TPALL Study

Blood ◽  
2014 ◽  
Vol 124 (21) ◽  
pp. 383-383
Author(s):  
Martin Pule ◽  
Sara Ghorashian ◽  
Laura Clifton-Hadley ◽  
Paul Smith ◽  
Soraya Saiagh ◽  
...  
Keyword(s):  
T Cells ◽  
Interim Analysis ◽  
The Other ◽  
Single Chain ◽  
Dismal Prognosis ◽  
Single Chain Fv ◽  
Post Infusion ◽  
Novel Strategy ◽  
Ebv Viremia

Abstract Introduction Patients with acute lymphoblastic leukaemia (ALL) relapsing after allogeneic stem cell transplantation (SCT) have a dismal prognosis. Recent clinical trials with T cells engineered to express 2nd generation CD19 chimeric antigen receptors (CARs) incorporating co-stimulatory domains for improved persistence and expansion report unprecedented anti-leukemic responses. However, responses are associated with Cytokine Release Syndrome (CRS) due to supra-physiological activation of the redirected T-cells. As an alternative, we studied use of donor-derived Epstein Barr virus (EBV)-specific T cells (CTL) transduced with a 1st generation CD19CAR as effectors, relying on signalling through the endogenous T cell receptor (TCR) to drive more physiological proliferation and persistence. This has enabled us to investigate a novel strategy to facilitate the expansion/persistence of CD19CAR T cells by vaccination with irradiated donor-derived, EBV transformed lymphoblastoid cell lines (LCL). We are conducting a European multi-centre phase I/II study of this approach in patients with pediatric ALL relapsing after SCT and report our interim findings. Methods Donor-derived EBV-specific CTL were generated from 80mls donor blood by repetitive stimulation with LCL, followed by transduction with an SFG retroviral vector encoding a CD19CAR consisting of the FMC63 single chain Fv linked to a CD3ζ endodomain. Patients were eligible for CD19CAR CTL therapy either pre-emptively if they became MRD-positive (> 5 x 10-4 in BM) within the 1st year post-SCT or prophylactically at day 60-70 post-2nd SCT. All patients had early withdrawal of immunosuppression and received lymphodepletion with fludarabine 90 mg/m2. Patients with detectable residual disease also received cytoreduction with vincristine/dexamethasone prior to infusion of cryopreserved CD19CAR CTL. Persistence of CAR CTL was measured by quantitative PCR and flow cytometry of blood. Disease status was assessed by morphology and IgH MRD analysis on bone marrow samples. The study design incorporated an interim analysis, allowing for vaccination with irradiated LCL if CD19CAR CTL were not detectable in 50% of patients at 2 months post-infusion. Results So far, 20 patients have been recruited (14 pre-emptive, 6 prophylactic arm) and 7 patients treated (3 pre-emptive, 4 prophylactic). The infused cell dose was 2 x 108/m2 in 6 patients and 4 x 107/m2 in the other. CD19CAR expression varied from 12.1-58.9%. No grade 3-5 toxicity was noted. In particular, no CRS, neurotoxicity or graft versus host disease (GVHD) attributable to CD19CAR CTL was seen. B-cell depletion was transient, lasting 1-2 months. In terms of disease response, 2 patients treated prophylactically remain in MRD negative remission after 3 and 17 months’ follow-up. A further patient showed transient clearance of BM MRD following immunotherapy in association with EBV viremia. He subsequently relapsed but has stable disease after retreatment with CD19CAR CTL with LCL vaccination. The other 4 patients had disease progression between 2 weeks and 3 months post-CD19CAR CTL infusion. At a median follow-up of 8 months, 2 patients have died of relapse, 3 are alive with disease and 2 remain disease-free. A planned interim analysis of the initial 6 patients treated with CD19CAR CTL alone showed poor expansion/persistence of CD19CAR CTL which were only detectable in the blood in 1 patient up to 28 days post-infusion. This may reflect that only 1 patient had EBV viremia at the time CD19CAR CTL were infused. In view of this, a second trial cohort received subcutaneous vaccination with irradiated, donor-derived LCL at 2 days before and at 1 and 2 months following CD19CAR CTL infusion to provide signalling through the endogenous EBV-specific TCR. So far, 2 patients have been vaccinated and a 3rd is planned shortly. Data on the effect of vaccination on CD19CAR CTL expansion/persistence will be presented. Conclusions This ongoing study shows safety of adoptive immunotherapy with donor EBV CTL transduced with a 1st generation CD19CAR in paediatric patients with ALL relapsing post allo-SCT. However, in the absence of a co-stimulatory domain in vivo expansion and persistence of transferred CTL is poor. We are investigating whether vaccination with irradiated, donor-derived EBV LCL improves persistence and efficacy of CAR transduced T cells and initial data on this approach will be presented Disclosures Pule: Cellectis: Martin Pule's laboratory receives funding for contract research from Cellectis Therapeutics Other.

scholarly journals Carotenoids and Periodontal Infection

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 269
Author(s):  
Koji Naruishi
Keyword(s):  
Diabetes Mellitus ◽  
Infectious Disease ◽  
Blood Stream ◽  
The Other ◽  
Low Grade ◽  
Gram Negative Bacteria ◽  
Systemic Diseases ◽  
Gram Negative ◽  
Periodontal Infection ◽  
Novel Strategy

Periodontitis is a polymicrobial infectious disease that leads to inflammation of the gingiva, resulting in teeth loss by various causes such as inflammation-mediated bone resorption. Recently, many investigators have reported that the periodontitis resulting from persistent low-grade infection of Gram-negative bacteria such as Porphyromonas gingivalis (Pg) is associated with increased atherosclerosis, diabetes mellitus, and other systemic diseases through blood stream. On the other hand, carotenoids belong among phytochemicals that are responsible for different colors of the foods. It is important to examine whether carotenoids are effective to the inhibition of periodontal infection/inflammation cascades. This review summarizes the advanced state of knowledge about suppression of periodontal infection by several carotenoids. A series of findings suggest that carotenoids intake may provide novel strategy for periodontitis treatment, although further study will be needed.

scholarly journals DIGITAL THERMOMETER BY USING AT89C51 MICROCONTROLLER

2020 ◽  
pp. 261-265
Author(s):  
Rajdip Das ◽  
Soumen Khatua
Keyword(s):  
Temperature Sensor ◽  
Human Error ◽  
Digital Circuits ◽  
Serial Communication ◽  
The Other ◽  
Digital Converter ◽  
Analog To Digital ◽  
Digital Thermometer ◽  
Lcd Display ◽  
The World

Automation is nowadays a new trend of Electronics. This automation has been implemented by the help of microcontrollers. If a microcontroller is programmed efficiently then it is capable to work efficiently as human. This era of automation has reduced so much human efforts. In this century some changes has taken place in the field of technology. The most important of those is the use of digital circuits in everywhere. The world of digitization has made things easier than before or we can say it has reduced human error in most of the areas. In our research we have made a digital thermometer by using AT89C51 microcontroller. The other components we have used are LM35 temperature sensor, Analog to Digital converter IC (ADC0804), MAX-232 IC chip for serial communication with the microcontroller and LCD display to display the temperature. We hope that this research paper will be helpful to scientific improvement in the field of making Digital thermometers to a great extent. KEYWORDS—DigitalThermo,Microcontroller,Timer,Temperature Sensor.

scholarly journals Using Novel One-Bit ADC to Design n-Bit ADC

2019 ◽  
Vol 8 (11) ◽  
pp. 4190-4195
Keyword(s):  
Input Voltage ◽  
The Other ◽  
The Novel ◽  
Digital Converter ◽  
Analog To Digital ◽  
Main Design ◽  
Single Output ◽  
Analog Voltage ◽  
Design Style ◽  
Main Design Parameter

This work presents two novel styles for designing nbit analog to digital converter (ADC). Each of the proposed ADCs is built using novel one-bit cell. The novel cell produces single output bit as a response to an input voltage, in addition, it outputs another analog voltage. The generated analog voltage is used again as an input to the to generate one more bit, and new analog voltage, and so on. The proposed n-bit ADC is built using the novel one-bit cell in two different styles. One design style, by connecting n ADC cells together to construct n-bit ADC that produces parallel binary outputs. The other design style realizes the n-bit ADC using single ADC cell and outputs n-bit serially. In both ADC designs introduced in this work, modularity was the main design parameter. The two different n-bit ADCs have been simulated. The first n-bit ADC with parallel outputs produces clean outputs at 50MS/s, and the other ADC design shows clean serial bits at 5KS/s

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