THz Spectroscopy of Food, Industrial and Pharmaceutical Paraffin Wax

2014 ◽  
Vol 602-605 ◽  
pp. 2675-2679
Author(s):  
Xu Sheng Kang ◽  
Ping Jie Huang ◽  
Xian Li ◽  
Di Bo Hou ◽  
Jin Hui Cai ◽  
...  

The absorption coefficient spectra and refractive index spectra of food grade, industrial grade and pharmaceutical grade paraffin wax, the three different types of paraffin wax within the terahertz frequency range from 0.2 to 2.2 THz are measured using transmission-type terahertz time-domain spectroscopy. The average refractive indexes of food grade, industrial grade and pharmaceutical grade paraffin wax in the frequency range are respectively 1.50, 1.49 and1.46. The three different types of paraffin wax all have weak absorption for terahertz waves and each paraffin wax have several obvious absorption peaks. However, all found absorption peak positions of the three different types of paraffin wax are so close that the three are relatively difficult to be identified using transmission-type terahertz technique in present experimental conditions.

Pharmaceutics ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 32
Author(s):  
Anna Baranova ◽  
Anastasiya Lykina ◽  
Daria Antonova ◽  
Olga Smolyanskaya

Lactose is a commonly used component of pharmaceutical medications in tablet form. It was previously shown that lactose changes conformationally after saturation in fluidized beds with active pharmaceutical ingredients obtained by repeated dilution of antibodies to interferon-gamma in combination with an external intensive vibration treatment. Moreover, it was revealed that these solutions are self-organized dispersed systems in which nano-objects are formed. Their biological activity and mechanism of action were previously established as well. The current work was dedicated to investigating the optical properties of fluidized lactose powders in the terahertz frequency range. Spectral analyses of powders of crystalline lactose saturated in fluidized beds with a diluted solution of either glycine buffer, antibodies to interferon-gamma, or water were carried out, intact lactose served as a control. All powders were tableted before testing. In the course of the study, the macroscopic parameters of the tablets were established, at which they had a stable shape and their THz optical properties had no parasitic diffraction losses. These tablets were analyzed using terahertz time-domain spectroscopy in the frequency range of 0.2–2.6 THz. The differentiation between the spectra was conducted using a principal component analysis. The differences between intact lactose and the lactose saturated with any of studied solutions were demonstrated. Additionally, lactose saturated with solutions of multiple dilutions of a substance (antibodies or glycine buffer) differed not only from intact lactose, but also from lactose saturated with a diluted solution of water. Moreover, discrimination of lactose formulations saturated with different substances (antibodies or glycine buffer) was also possible. Additionally, intact lactose differed from lactose saturated with diluted water. The methods reported could be useful for the quality control of the medications based on the technology of repeated dilution of an original substance.


Author(s):  
V. R. Bilyk ◽  
K. A. Grishunin

The recent progress in terahertz time-domain spectroscopy enables the accurate and reliable measurements of dielectric properties in comparison with the traditional far-infrared spectroscopy using an incoherent light source. The broadband THz-TDS is a powerful tool to determine the real and imaginary parts of a complex dielectric constant by the transmission which allows to detect the parameters of the soft modes in ferroelectrics. In this work, the terahertz time-domain spectroscopy was used to investigate the dependence of the complex refractive index of a single-crystal quantum paraelectric strontium titanate in the terahertz frequency range from 0.3 to 2 THz. It was shown that the low-frequency terahertz response of the material is determined by the soft phonon mode TO1. The measured experimental dependences showed a good agreement with the theoretical curves obtained from the analysis of the Lorentz oscillator model for the complex dielectric constant of strontium titanate. The obtained results are necessary for understanding the principle of possibility to manipulate the order parameter in ferroelectric materials and can be used to create energy-efficient memory devices with a speed of recording information close to the theoretical limit.


2015 ◽  
Vol 74 (19) ◽  
pp. 1767-1776 ◽  
Author(s):  
V. I. Bezborodov ◽  
O.S. Kosiak ◽  
Ye. M. Kuleshov ◽  
V. V. Yachin

2017 ◽  
Vol 76 (10) ◽  
pp. 929-940 ◽  
Author(s):  
Yu. S. Kovshov ◽  
S. S. Ponomarenko ◽  
S. A. Kishko ◽  
A. A. Likhachev ◽  
S. A. Vlasenko ◽  
...  

2013 ◽  
Vol 52 (25) ◽  
pp. 6364 ◽  
Author(s):  
Lin’an Li ◽  
Wei Song ◽  
Zhiyong Wang ◽  
Shibin Wang ◽  
Mingxia He ◽  
...  

2021 ◽  
Author(s):  
Seiichiro Ariyoshi ◽  
Satoshi Ohnishi ◽  
Hikaru Mikami ◽  
Hideto Tsuji ◽  
Yuki Arakawa ◽  
...  

Poly(L-lactide) (PLLA) was investigated by Fourier transform terahertz (THz) spectroscopy over the frequency range of 1.0 – 8.5 THz. THz absorption spectra were acquired for PLLA samples isothermally crystallized at...


Photonics ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 76
Author(s):  
Mikhail K. Khodzitsky ◽  
Petr S. Demchenko ◽  
Dmitry V. Zykov ◽  
Anton D. Zaitsev ◽  
Elena S. Makarova ◽  
...  

The terahertz frequency range is promising for solving various practically important problems. However, for the terahertz technology development, there is still a problem with the lack of affordable and effective terahertz devices. One of the main tasks is to search for new materials with high sensitivity to terahertz radiation at room temperature. Bi1−xSbx thin films with various Sb concentrations seem to be suitable for such conditions. In this paper, the terahertz radiation influence onto the properties of thermoelectric Bi1−xSbx 200 nm films was investigated for the first time. The films were obtained by means of thermal evaporation in vacuum. They were affected by terahertz radiation at the frequency of 0.14 terahertz (THz) in the presence of thermal gradient, electric field or without these influences. The temporal dependencies of photoconductivity, temperature difference and voltage drop were measured. The obtained data demonstrate the possibility for practical use of Bi1−xSbx thin films for THz radiation detection. The results of our work promote the usage of these thermoelectric materials, as well as THz radiation detectors based on them, in various areas of modern THz photonics.


Electronics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 268
Author(s):  
Victor Pacheco-Peña

The terahertz frequency range (0 [...]


2021 ◽  
Vol 7 (15) ◽  
pp. eabf9809
Author(s):  
Sergey Kovalev ◽  
Hassan A. Hafez ◽  
Klaas-Jan Tielrooij ◽  
Jan-Christoph Deinert ◽  
Igor Ilyakov ◽  
...  

Graphene is conceivably the most nonlinear optoelectronic material we know. Its nonlinear optical coefficients in the terahertz frequency range surpass those of other materials by many orders of magnitude. Here, we show that the terahertz nonlinearity of graphene, both for ultrashort single-cycle and quasi-monochromatic multicycle input terahertz signals, can be efficiently controlled using electrical gating, with gating voltages as low as a few volts. For example, optimal electrical gating enhances the power conversion efficiency in terahertz third-harmonic generation in graphene by about two orders of magnitude. Our experimental results are in quantitative agreement with a physical model of the graphene nonlinearity, describing the time-dependent thermodynamic balance maintained within the electronic population of graphene during interaction with ultrafast electric fields. Our results can serve as a basis for straightforward and accurate design of devices and applications for efficient electronic signal processing in graphene at ultrahigh frequencies.


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