Synthesis and Characteristic of Molecularly Imprinted Polymer Immobilized Mesoporous Silica Sphere for Selective Binding of S-Naproxen

2008 ◽  
Vol 47-50 ◽  
pp. 890-893
Author(s):  
Nai Ci Bing ◽  
Zhen Tian ◽  
Sheng Wen Chen ◽  
Qing Hua Li ◽  
Zheng Liang Xu
Keyword(s):  
Mesoporous Silica ◽  
Binding Capacity ◽  
Stationary Phases ◽  
Chiral Separations ◽  
Silica Sphere ◽  
Template Molecule ◽  
Structural Morphology ◽  
Molecularly Imprinted ◽  
Surface Imprinting Technique ◽  
Mesoporous Silica Sphere

Molecularly imprinted composite materials (PM) selective to S-naproxen were prepared in the surface of mesoporous silica sphere (SBA-15) by surface imprinting technique. FT-IR, SEM and surface area analysis were used to study the structural morphology of PM and MIPs particles and probe the incorporation of polymer into the SBA-15 framework. The results revealed that PM showed better binding affinity and selectivity to the template molecule than MIPs and the maximum saturated binding capacity of PM to S-naproxen and R-naproxen was about 10.3332 and 6.0063µmol·g-1. Meanwhile, we achieve a reference strategy for the development of molecularly imprinting polymer for drugs and to handle forms in certain applications such as chromatographic stationary phases for chiral separations.

Controllable Imprinted Polymer Layer Coated Silica-Gel for S-1-(1-Naphthyl) Ethylamine Recognition by ATRP

2012 ◽  
Vol 508 ◽  
pp. 237-240 ◽  
Author(s):  
Nai Ci Bing ◽  
Xiang Rong Zhu ◽  
Zhen Tian ◽  
Hong Yong Xie ◽  
Li Jun Wang
Keyword(s):  
Silica Gel ◽  
Stationary Phases ◽  
Chiral Separations ◽  
Polymer Layer ◽  
Imprinted Polymer ◽  
Uv Spectrum ◽  
Structural Morphology ◽  
Molecularly Imprinted ◽  
Molecularly Imprinting Polymer ◽  
Ft Ir

Controlled grafting ofS-1-(1-naphthyl) Ethylamine-imprinting polymer layer on the silica-gel was carried out by the surface-initiated atom transfer radical polymerization (ATRP). Polymerization time was used as the independent variable to manipulate the amount of grafted imprinting polymer on the silica-gel. For comparison, molecularly imprinted polymers (MIPs) without silica-gel also prepared at the same condition. SEM, FT-IR and UV spectrum were used to study the structural morphology and selectivity of polymers and probe the incorporation of imprinted polymer layer on the surface of substrates. Results indicate that the integration of ATRP and molecularly imprinted polymerization realize preparation of molecular selective polymers and it is possible to tune selectivity and morphology in rational way by changing polymerization times. Meanwhile, we achieve a reference strategy for the development of molecularly imprinting polymer for drugs and to handle forms in certain applications such as chromatographic stationary phases for chiral separations.

A New Molecularly Imprinted Polymer Prepared by Surface Imprinting Technique for Selective Adsorption towards Rhodamine B

2014 ◽  
Vol 998-999 ◽  
pp. 19-22 ◽  
Author(s):  
Guang Shan Xuan ◽  
Qin Yong Sun ◽  
Xiao Zheng
Keyword(s):  
Rhodamine B ◽  
High Performance ◽  
Dissociation Constants ◽  
Selective Adsorption ◽  
Binding Capacity ◽  
Template Molecule ◽  
Dynamic Binding ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Surface Imprinting Technique

A new molecularly imprinted polymers (Rhodamine B-KH-570/SiO2,MIPS) with high performance for recognizing Rhodamine B was prepared by adopting the surface molecular imprinting technique with silica-gel modified by KH-570 as a carrier material, acrylamide as the functional monomer and N,N-methylene-bis-acrylamide (MBA) as the crosslinker.The static adsorption experiments indicated that MIPS had significantly higher adsorption capacity for Rhodamine B than its non-imprinted polymers (NIPS). Dynamic binding study showed that the MIPS had good site accessibility and mass transport for Rhodamine B.Scatchard analysis revealed that two classes of binding sites were formed in MIPS with dissociation constants of 0.086mol/L and 0.0076 mol/L, and the maximum apparent binding capacity was 96.00μmol/g and 50.07 μmol/g, respectively.The selectivity coefficients and separation factors of MIPS for Rhodamine B in relation to competition species Rhodamine123 were 131.51 and 3.86 respectively, which suggested that MIPS had high recognition selectivity and binding affinity for the template molecule Rhodamine B.

scholarly journals Removal of bisphenol A from aqueous media using a highly selective adsorbent of hybridization cyclodextrin with magnetic molecularly imprinted polymer

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
S. Mamman ◽  
F. B. M. Suah ◽  
M. Raaov ◽  
F. S. Mehamod ◽  
S. Asman ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Molecularly Imprinted Polymer ◽  
Binding Capacity ◽  
Bulk Polymerization ◽  
Resonance Spectroscopy ◽  
Template Molecule ◽  
Order Kinetic ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Magnetic Molecularly Imprinted Polymer

In this study, a unique magnetic molecularly imprinted polymer (MMIP) adsorbent towards bisphenol A (BPA) as a template molecule was developed by bulk polymerization using β-cyclodextrin (β-CD) as a co-monomer with methacrylic acid (MAA) to form MMIP MAA–βCD as a new adsorbent. β-CD was hybridized with MAA to obtain water-compactible imprinting sites for the effective removal of BPA from aqueous samples. Benzoyl peroxide and trimethylolpropane trimethacrylate were used as the initiator and cross-linker, respectively. The adsorbents were characterized by Fourier transform infrared spectroscopy, scanning electronic microscopy, transmission electron microscopy, vibrating sample magnetometer, Brunauer–Emmett–Teller and X-ray diffraction. 1 H nuclear magnetic resonance spectroscopy was used to characterize the MAA–βCD and BPA–MAA–βCD complex. Several parameters influencing the adsorption efficiency of BPA such as adsorbent dosage, pH of sample solution, contact time, initial concentrations and temperature as well as selectivity and reusability study have been evaluated. MMIP MAA–βCD showed significantly higher removal efficiency and selective binding capacity towards BPA compared to MMIP MAA owing to its unique morphology with the presence of β-CD. The kinetics data can be well described by the pseudo second-order kinetic and Freundlich isotherm and Halsey models best fitted the isotherm data. The thermodynamic studies indicated that the adsorption reaction was a spontaneous and exothermic process. Therefore, MMIP based on the hybrid monomer of MAA–βCD shows good potential of a new monomer in molecularly imprinted polymer preparation and can be used as an effective adsorbent for the removal of BPA from aqueous solutions.

Mesoporous Silica Sphere−Polysulfone Mixed Matrix Membranes for Gas Separation

Langmuir ◽  
2009 ◽  
Vol 25 (10) ◽  
pp. 5903-5909 ◽  
Author(s):  
Beatriz Zornoza ◽  
Silvia Irusta ◽  
Carlos Téllez ◽  
Joaquín Coronas
Keyword(s):  
Mesoporous Silica ◽  
Gas Separation ◽  
Silica Sphere ◽  
Mixed Matrix Membranes ◽  
Mixed Matrix ◽  
Mesoporous Silica Sphere ◽  
Matrix Membranes

Cholesterol-Imprinted Receptor Using Chitosan Derivative as the Precursor

2013 ◽  
Vol 699 ◽  
pp. 712-717
Author(s):  
Huai Min Guan ◽  
Yue Jin Tong ◽  
Jin Hua Zheng ◽  
Xiang Li
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Polar Solvent ◽  
Binding Capacity ◽  
Template Molecule ◽  
Chitosan Derivative ◽  
Amino Groups ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Selective Protection ◽  
Selection Of

Research has been focused on the development of molecularly imprinted polymers using a chitosan derivative as the precursor. An O-acyl chitosan was synthesized by the selective protection of amino groups of chitosan in MeSO3H and was cross-linked with glutaraldehyde in the presence/ absence of template molecule, cholesterol. The effect of the degree of the acyl substitution on the selection of precursor was investigated, regarding the solubility of chitosan derivative, interaction between the precursor and imprinted molecule, and degree of the cross-linking of precursor. The rebinding experiments indicated the significant recognition for cholesterol with imprinted polymer as compared with non-imprinted polymer. It was found that a good binding capacity of the imprinted polymer towards cholesterol could be achieved in a less-polar solvent. And the O-acyl chitosan-based molecularly imprinted polymer obtained displayed good recognition selectivity for cholesterol in comparison to similarly strctural analogue, cholesterol acetate.

Study on the Weakest Interaction Model for Chiral Resolution Using Molecularly Imprinted Polymer

2011 ◽  
Vol 391-392 ◽  
pp. 111-115 ◽  
Author(s):  
Fei Rong ◽  
Ping Li
Keyword(s):  
Chiral Separation ◽  
Molecularly Imprinted Polymers ◽  
Separation Factor ◽  
High Performance ◽  
Stationary Phases ◽  
Interaction Model ◽  
Template Molecule ◽  
Separation Procedure ◽  
Recognition Mechanism ◽  
Molecularly Imprinted

Molecularly imprinted polymers (MIPs) of L-phenylalanine ethyl ester were synthesized in this study. Then, the prepared MIPs were packed in a stainless column and evaluated as the chiral stationary phases of high performance liquid chromatography (HPLC). The MIPs exhibited a considerable capability of chiral separation between template molecule and its enantiomer with the separation factor of 1.69. Furthermore, the weakest interaction model was introduced to study the chiral recognition mechanism of MIPs. The results suggested that the weakest interaction between the template molecule and the imprinted cavity played crucial role in chiral separation, and the molecular tension should be taken into consideration during the separation procedure. The separation factor of 2.07 was calculated by the theoretical model, which was very close to the value obtained from chromatographic experiment.

Rattle-Type Diamine-Functionalized Mesoporous Silica Sphere for Carbon Dioxide Adsorption

2018 ◽  
Vol 53 ◽  
pp. 13-21 ◽  
Author(s):  
Ning Yuan ◽  
Zhi Wei Liu ◽  
Li Yan Wang ◽  
Bao Hang Han
Keyword(s):  
Carbon Dioxide ◽  
Mesoporous Silica ◽  
Nitrogen Adsorption ◽  
Magic Angle Spinning ◽  
Silica Sphere ◽  
Magic Angle ◽  
Templating Method ◽  
Functionalized Mesoporous Silica ◽  
Angle Spinning ◽  
Mesoporous Silica Sphere

A rattle-type diamine-functionalized mesoporous silica sphere (DA-RMSS) was fabricated stepwise using a self-templating method through cationic surfactant assisted selective etching strategy. The rattle-type morphology of the obtained DA-RMSS material was disclosed by transmission electron microscopy, while its chemical composition was characterized by CHN elemental analysis, Fourier transform infrared spectroscopy, and solid-state 29Si cross-polarization/magic-angle-spinning nuclear magnetic resonance spectroscopic measurement, which corroborates the successful formation of siloxane network and the incorporation of organic component. Moreover, nitrogen adsorption–desorption isotherm measurement was conducted to reveal that DA-RMSS possesses large Brunauer–Emmett–Teller (BET) specific surface area of 814 m2g–1, pore volume of 0.78 cm3g–1, and narrow pore size distribution centered at 3.0 nm. Furthermore, its uptake property on carbon dioxide was also investigated in this contribution.

A Novel Semi-aromatic Polyamide/Mesoporous Silica Sphere Nanocomposite Membrane with Superior Separation Performance

2016 ◽  
Vol 45 (2) ◽  
pp. 214-216 ◽  
Author(s):  
Qiang Li ◽  
Meng Zhang ◽  
Jie Song ◽  
Xianhui Pan ◽  
Hui Yu ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Aromatic Polyamide ◽  
Silica Sphere ◽  
Nanocomposite Membrane ◽  
Separation Performance ◽  
Mesoporous Silica Sphere
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