Optimization of Conditions for Calcium Lactate Nano-Particle Production by Chemical Precipitation
In this paper, the optimization of conditions for calcium lactate nano-particle production by chemical precipitation by the orthogonal method was reported. The optimal conditions for enhancing yield and purity of calcium lactate were determined as: mixture ratio between lactic acid and Ca(OH)21.35:1, Ca(OH)20.46 mol•L-1, lactic acid 6 mol•L-1, reaction temperature 50 °C,reaction time 30 min, reaction mixing speed 500 r•min-1, mixture ratio between the volume of alcohol addition and total reaction 1:1. This optimization strategy lead to an calcium lactate nano-particle yield of 85% and the purity of 98%, which was considerably higher than that obtained in preliminary studied. The TEM images shown that the width of the calcium lactate was about 100 nm.