A Novel Nonenzymatic Glucose Sensor Based on Polydopamine-Nanoplatinum Composites Modified Electrode

2013 ◽  
Vol 726-731 ◽  
pp. 13-16
Author(s):  
Ying Zhang ◽  
Cai Na Su ◽  
Wang Ren
Keyword(s):  
Electrochemical Method ◽  
Electrocatalytic Oxidation ◽  
Glucose Sensor ◽  
Pt Nanoparticles ◽  
Serum Samples ◽  
Nonenzymatic Glucose Sensor ◽  
Sensitivity And Selectivity ◽  
One Step ◽  
Response Current ◽  
Oxidation Of Glucose

We reported a facile one-step electrochemical method to synthesize compositesof polydopamine (PDA) and Pt nanoparticles (PtNs) at the glassy carbon electrode (GCE). The electrochemical behavior of the obtained platform towards electrocatalytic oxidation of glucose in alkaline solution was investigated by cyclic voltammetry (CV). The response current of the resultant sensor is linear to glucose concentration in the range of 0.1- 30.0 mM with a low detection limit of 1.0 μM (S/N=3). The proposed sensor with excellent sensitivity and selectivity also allows for detection of glucose in human serum samples.

A comparative study of electrocatalytic oxidation of glucose on conductive Ni-MOF nanosheet arrays with different ligands

2020 ◽  
Vol 44 (41) ◽  
pp. 17849-17853
Author(s):  
Yanxia Qiao ◽  
Rui Zhang ◽  
Fangyuan He ◽  
Wenli Hu ◽  
Xiaowei Cao ◽  
...  
Keyword(s):  
Detection Limit ◽  
Comparative Study ◽  
Response Time ◽  
Electrocatalytic Oxidation ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Fast Response ◽  
Serum Samples ◽  
Nanosheet Arrays ◽  
Oxidation Of Glucose

A glucose sensor based on conductive Ni-MOF nanosheet arrays/CC exhibits a fast response time, a low detection limit, a high sensitivity, and it can also be applied for the detection of glucose in human serum samples.

One-step synthesis of novel Cu@polymer nanocomposites through a self-activated route and their application as nonenzymatic glucose sensors

2017 ◽  
Vol 46 (30) ◽  
pp. 9918-9924 ◽  
Author(s):  
Yinlin Tong ◽  
Jiaying Xu ◽  
Hong Jiang ◽  
Feng Gao ◽  
Qingyi Lu
Keyword(s):  
Polymer Nanocomposites ◽  
Glucose Sensor ◽  
Glucose Sensors ◽  
Core Shell ◽  
Nonenzymatic Glucose Sensor ◽  
One Step

Novel core–shell Cu@polymer nanocomposites were synthesized through a one-step self-activated route and developed as nonenzymatic glucose sensor.

One-step synthesis of Pt–NiO nanoplate array/reduced graphene oxide nanocomposites for nonenzymatic glucose sensing

2015 ◽  
Vol 3 (2) ◽  
pp. 608-616 ◽  
Author(s):  
Li Wang ◽  
Xingping Lu ◽  
Cunjin Wen ◽  
Yingzhen Xie ◽  
Longfei Miao ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Glucose Sensor ◽  
Glucose Sensing ◽  
Nonenzymatic Glucose Sensor ◽  
Reduced Graphene ◽  
One Step

A novel nonenzymatic glucose sensor was constructed based on rGO supported Pt–NiO nanoplate arrays through a simple one-step synthesis.

Ni Hierarchical Structures Supported on Titania Nanowire Arrays as Efficient Nonenzymatic Glucose Sensor

2020 ◽  
Vol 20 (5) ◽  
pp. 3246-3251 ◽  
Author(s):  
Hai-Long Hu ◽  
Chuan He ◽  
Bao-Gang Guo ◽  
He-Yan Huang ◽  
Xing-Quan Zhang ◽  
...  
Keyword(s):  
Glucose Sensor ◽  
Low Cost ◽  
Hierarchical Structures ◽  
High Sensitivity ◽  
Fast Response ◽  
Nanowire Arrays ◽  
Nonenzymatic Glucose Sensor ◽  
Conductive Substrate ◽  
Nano Sensors ◽  
Oxidation Of Glucose

Developing new advanced nonenzymatic electrochemical nano-sensors for glucose detection has attracted intensive attraction. In this work, we designed a novel nanocomposite nonenzymatic glucose sensor by fabricating hierarchically nanostructured metal nickel on titania nanowire arrays, which was loaded on a transparent conductive substrate (i.e., fluorine-doped tin oxide, FTO) surface by mild hydrothermal method. Due to the large surface area of the hierarchically nanostructured Ni and fast electron transfer of the TiO2 nanowire arrays electrode, the nanocomposite electrode shows excellent electrochemical activity toward the oxidation of glucose. The electrode exhibits high sensitivity in detecting glucose concentration (1472 μA mM−1 cm−2) with a wide linear range from 2×10−4 M to 2×10−3 M, fast response time (within 5 s), and small detection limit (10 μM) (S/N = 3). The good analytical performance, low cost and simple preparation method make this novel electrode material promising for the development of effective glucose nonenzymatic glucose sensor.

One-step electrodeposition of a nickel cobalt sulfide nanosheet film as a highly sensitive nonenzymatic glucose sensor

2016 ◽  
Vol 4 (47) ◽  
pp. 7540-7544 ◽  
Author(s):  
Xiaoqin Cao ◽  
Kunyang Wang ◽  
Gu Du ◽  
Abdullah M. Asiri ◽  
Yongjun Ma ◽  
...  
Keyword(s):  
Glucose Sensor ◽  
High Sensitivity ◽  
Cobalt Sulfide ◽  
Nonenzymatic Glucose Sensor ◽  
Long Term Stability ◽  
Nickel Cobalt ◽  
Response Range ◽  
Highly Sensitive ◽  
One Step ◽  
Electrodeposited Nickel

An electrodeposited nickel cobalt sulfide nanosheet film acts as a nonenzymatic glucose sensor with wide linear response range of 0.001–3 mM, low detection limit of 0.12 μM, high sensitivity of 3291.5 μA mM−1 cm−2, as well as good selectivity and long-term stability.

Templating synthesis of hollow CuO polyhedron and its application for nonenzymatic glucose detection

2014 ◽  
Vol 2 (20) ◽  
pp. 7306-7312 ◽  
Author(s):  
Chuncai Kong ◽  
Linli Tang ◽  
Xiaozhe Zhang ◽  
Shaodong Sun ◽  
Shengchun Yang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Modified Electrode ◽  
Glucose Sensor ◽  
High Sensitivity ◽  
Fast Response ◽  
Good Stability ◽  
Glucose Detection ◽  
Nonenzymatic Glucose Sensor ◽  
Oxidation Of Glucose ◽  
Templating Synthesis

In this paper, we successfully fabricated a novel type of a hollow CuO polyhedron that consists of numerous nanoplates using Cu2O as a template. The hollow CuO polyhedron-modified electrode exhibits high sensitivity, low detection limit, good stability and fast response towards the oxidation of glucose, suggesting it to be a promising nonenzymatic glucose sensor.

scholarly journals Development and validation of a one-step reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid detection of ZIKV in patient samples from Brazil

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Severino Jefferson Ribeiro da Silva ◽  
Keith Pardee ◽  
Udeni B. R. Balasuriya ◽  
Lindomar Pena
Keyword(s):  
Reverse Transcription ◽  
Rapid Detection ◽  
Quantitative Polymerase Chain Reaction ◽  
Rna Extraction ◽  
Lamp Assay ◽  
Isothermal Amplification ◽  
Serum Samples ◽  
Low Resource ◽  
Loop Mediated Isothermal Amplification ◽  
One Step

AbstractWe have previously developed and validated a one-step assay based on reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid detection of the Zika virus (ZIKV) from mosquito samples. Patient diagnosis of ZIKV is currently carried out in centralized laboratories using the reverse transcription-quantitative polymerase chain reaction (RT-qPCR), which, while the gold standard molecular method, has several drawbacks for use in remote and low-resource settings, such as high cost and the need of specialized equipment. Point-of-care (POC) diagnostic platforms have the potential to overcome these limitations, especially in low-resource countries where ZIKV is endemic. With this in mind, here we optimized and validated our RT-LAMP assay for rapid detection of ZIKV from patient samples. We found that the assay detected ZIKV from diverse sample types (serum, urine, saliva, and semen) in as little as 20 min, without RNA extraction. The RT-LAMP assay was highly specific and up to 100 times more sensitive than RT-qPCR. We then validated the assay using 100 patient serum samples collected from suspected cases of arbovirus infection in the state of Pernambuco, which was at the epicenter of the last Zika epidemic. Analysis of the results, in comparison to RT-qPCR, found that the ZIKV RT-LAMP assay provided sensitivity of 100%, specificity of 93.75%, and an overall accuracy of 95.00%. Taken together, the RT-LAMP assay provides a straightforward and inexpensive alternative for the diagnosis of ZIKV from patients and has the potential to increase diagnostic capacity in ZIKV-affected areas, particularly in low and middle-income countries.

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