Preparation and Application of Low Molecular Weight Chitosan Nanoparticle as a Textile Finishing Agent

2013 ◽  
Vol 796 ◽  
pp. 92-97 ◽  
Author(s):  
Cheng Wang ◽  
Hong Lin ◽  
Yu Yue Chen ◽  
Yan Hua Lu
Keyword(s):  
Chitosan Nanoparticles ◽  
Low Molecular Weight ◽  
Silk Fabric ◽  
Wrinkle Resistance ◽  
Chitosan Nanoparticle ◽  
Low Molecular Weight Chitosan ◽  
Ft Ir ◽  
Textile Finishing ◽  
Finishing Agent ◽  
Silk Fabrics

Due to the advantages of both the chitosan and the nanomaterial, chitosan nanoparticle has a broad application in a lot of fields, such as medicine carrier, food process, cosmetics and agriculture protect. And there also appears a lot of research about chitosan nanoparticle in textile finishing in recent years. In former research, steady state chitosan nanoparticles were prepared by ionotropic gelation method in dispersion system. In this paper, in order to confirm the preparation of low molecular weight chitosan nanoparticle, it was also characterized by Fourier Transform Infrared (FT-IR) Spectrometry, X-ray diffraction (XRD) and Transmission Electron Microscope (TEM). Focusing on the application value, chitosan nanoparticles dispersion solution were used as one kind of textile finishing agent to modifyB.morisilk fabrics in order to realize the functionalization of silk fabrics. The wrinkle resistance and bacteria repellency of silk fabrics were tested in the paper. The results showed that chitosan nanoparticles were successfully prepared and confirmed accrording to the XRD, FT-IR and TEM tests. In addition, compared with the ordinaryB. morisilk fabric and theB. morisilk fabric treated with chitosan accordingly, theB. morisilk fabrics treated with chitosan nanoparticle dispersion system had better wrinkle resistance and bacteria repellency.

scholarly journals Chitosan Nanoparticles as a Percutaneous Drug Delivery System for Hydrocortisone

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Haliza Katas ◽  
Zahid Hussain ◽  
Tay Chai Ling
Keyword(s):  
Particle Size ◽  
Delivery System ◽  
Chitosan Nanoparticles ◽  
Entrapment Efficiency ◽  
Ionic Crosslinking ◽  
Low Molecular Weight Chitosan ◽  
Permeation Studies ◽  
Ft Ir ◽  
Inflammatory Drugs

Hydrocortisone (HC) has formed the mainstay for the management of atopic dermatitis. Hence, HC-loaded chitosan nanoparticles were prepared by ionic crosslinking of high, low molecular weight chitosan (HMwt, LMwt CS) and N-trimethyl chitosan (TMC) with tripolyphosphate. HC loading into CS nanoparticles was confirmed by FT-IR. The particle size of HC-loaded HMwt, LMwt, and TMC nanoparticles was increased from243±12,147±11,and124±9 nm to337±13,222±14,and195±7 nm, respectively, by increasing the pH of CS solution. Their respective zeta potential and entrapment efficiency (EE) were significantly decreased by increasing the pH of CS solution. The swelling ratios of HC loaded HMwt, LMwt, and TMC NPs were increased when the pH of incubating media (PBS) was increased. The same increasing trend was observed in particle size and EE of HC loaded as the CS concentration was increased. The HC loaded CS NPs were generally nonspherical.In-vitropermeation studies showed that HC was efficiently released from the CS NPs in QV cream while in aqueous cream CS NPs provided a sustained release for HC. Thus, it is anticipated that CS NPs are the promising delivery system for anti-inflammatory drugs.

scholarly journals Effect of Polysaccharide Sources on the Physicochemical Properties of Bromelain–Chitosan Nanoparticles

Polymers ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 1681 ◽  
Author(s):  
Janaína Artem Ataide ◽  
Eloah Favero Gérios ◽  
Letícia Caramori Cefali ◽  
Ana Rita Fernandes ◽  
Maria do Céu Teixeira ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Physicochemical Properties ◽  
Enzyme Stability ◽  
Proteolytic Enzymes ◽  
Chitosan Nanoparticles ◽  
Low Molecular Weight ◽  
Chitosan Oligosaccharide ◽  
Nanoparticle Suspension ◽  
Accelerated Stability ◽  
Low Molecular Weight Chitosan

Bromelain, a set of proteolytic enzymes potential pharmaceutical applications, was encapsulated in chitosan nanoparticles to enhance enzyme stability, and the effect of different chitosan sources was evaluated. Chitosan types (i.e., low molecular weight chitosan, chitosan oligosaccharide lactate, and chitosan from shrimp shells) produced nanoparticles with different physicochemical properties, however in all cases, particle size and zeta potential decreased, and polydispersity index increased after bromelain addition. Bromelain encapsulation was higher than 84% and 79% for protein content and enzymatic activity, respectively, with low molecular weight chitosan presenting the highest encapsulation efficiency. Nanoparticle suspension was also tested for accelerated stability and rheological behavior. For the chitosan–bromelain nanoparticles, an instability index below 0.3 was recorded and, in general, the loading of bromelain in chitosan nanoparticles decreased the cohesiveness of the final suspension.

Application of Sericin in Anti-Crease Finishing of Silk Fabric

2014 ◽  
Vol 707 ◽  
pp. 64-68
Author(s):  
Lei Xu
Keyword(s):  
Activation Energy ◽  
Thermal Decomposition ◽  
Sodium Hypophosphite ◽  
Cross Linking ◽  
Silk Fabric ◽  
Solvent Viscosity ◽  
Wrinkle Resistance ◽  
Integration Test ◽  
Finishing Agent ◽  
Recovery Angle

It is of perfect anti-crease effect that using sericin finishing agent in finishing of silk fabric. Analyzed integration test of wrinkle resistance of silk fabric, the optimally applied parameters are obtained as follows, the dosage of sericin is 15g/L, the concentration of TEA is 8g/L, twice dip and twice rolling, drying, baking in 3 minutes at 150 °C. The wrinkle recovery angle has been increased obviously after sericin finishing. Also the performance of anti-crease resistance can be improved effectively by adding 3g/L of sodium hypophosphite. The phenomena of increased solvent viscosity and activation energy of thermal decomposition were shown that the cross-linking structure were formed in the fiber with the using of sericin finishing, thereby the wrinkle resistance of the fabric was improved. Sericin finishing agent can increased the wrinkle resistant properties of fabrics effectively.

Study on the Preparation of Steady-State Chitosan Nanoparticle as Silk-Fabric Finishing Agent

2011 ◽  
Vol 175-176 ◽  
pp. 745-749
Author(s):  
Cheng Wang ◽  
Hong Lin ◽  
Yu Yue Chen
Keyword(s):  
Steady State ◽  
Ph Value ◽  
Chitosan Nanoparticles ◽  
Nano Particles ◽  
Diameter Distribution ◽  
Silk Fabric ◽  
Nanoparticle Dispersion ◽  
Ionotropic Gelation ◽  
Dispersion System ◽  
Chitosan Nanoparticle

The chitosan nanoparticles can be prepared by ionotropic gelation method in dispersion system. Chitosan nanoparticle has advantages of both the chitosan and the nano particles, and so it has a wide application in the textile finishing field. In this paper, the effects of the concentration of TPP, Span-80, deposited time and pH value on the diameter distribution of the chitosan nanoparticles are discussed in order to obtain the optimized preparation technics of steady state chitosan nanoparticle. The results show that chitosan nanoparticles are successfully prepared by ionotropic gelation method. Under the optimized preparation technics, chitosan nanoparticles disperse homogeneously in the system and have a good steady state. The average diameter of chitosan nanoparticle in the dispersion system is 20.82nm. Compared with the ordinary silk fabric, the B. mori silk fabric treated with chitosan nanoparticle dispersion system has better deepen effect of reactive dyes. The chitosan nanopartilce dispersion system is helpful to improve the dye uptake and dye fixation of silk fabrics.

Enhance of Tumor Targeting by Receptor-Mediated Endocytosis Using Low Molecular Water-Soluble Chitosan Nanoparticles Loaded with Anticancer Agent

2007 ◽  
Vol 342-343 ◽  
pp. 469-472 ◽  
Author(s):  
Dong Gon Kim ◽  
Min Ja Jang ◽  
Chang Yong Choi ◽  
Tae Hyeong Kim ◽  
Mi Kyeong Jang ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Anticancer Agent ◽  
Drug Carrier ◽  
Chitosan Nanoparticles ◽  
Water Soluble ◽  
Molecular Water ◽  
Low Molecular Weight ◽  
Receptor Mediated Endocytosis ◽  
Chitosan Nanoparticle ◽  
High Antitumor Activity

In this study, we prepared using low molecular weight water-soluble chitosan nanoparticle loaded paclitaxel (LMWSC-NPT) and investigated the potential as a drug carrier which is able to accumulate in the tumor site. In the experiment of receptor-mediated endocytosis, LMWSC-NPT was treated with sodium azid (NaN3) as an inhibitor of endocytosis process. As results, the antitumor activity of LMWSC-NPT treated with sodium azid didn’t show but LMWSC-NPT was shown the high antitumor activity. Therefore, LMWSC-NPs modified with hydrophobic group will be useful anticancer agent carrier via receptor-mediated endocytosis.

scholarly journals Sintesis Nanopartikel Kitosan-tripolifosfat menggunakan Metode Gelasi Ionik

2019 ◽  
Vol 19 (2) ◽  
pp. 155
Author(s):  
Risnawati Risnawati ◽  
Mohammad Wijaya M ◽  
Hasri Hasri
Keyword(s):  
Water Content ◽  
Freeze Drying ◽  
Chitosan Nanoparticles ◽  
Chitosan Solution ◽  
Acid Synthesis ◽  
Ionic Gelation ◽  
Chitosan Nanoparticle ◽  
Before And After ◽  
Ft Ir ◽  
The Stability

ABSTRAK Penelitian ini bertujuan untuk mensintesis nanopartikel kitosan menggunakan metode gelasi ionik. Tahapan sintesis meliputi: pembuatan larutan kitosan 0,2% menggunakan asam sitrat 5%, sintesis Nanopartikel Kitosan dengan Na-TPP sebagai pengikat silang, dilanjutkan dengan uji kestabilan nanopartikel menggunakan spektrofotometer UV-Vis. Hasil sintesis nanopatikel dikarakterisasi menggunakan FT-IR, PSA dan uji kadar air. Hasil penelitian menunjukkan bahwa suspensi nanopartikel kitosan-TPP tetap stabil selama penyimpanan 1 hari dan setelah freeze drying diperoleh serbuk berwarna putih dengan kadar air sebesar 7,25%. Hasil Karakterisasi FT-IR mengindikasikan bahwa sintesis nanopatikel telah terbentuk, hal ini dapat dilihat terjadinya pergeseran puncak serapan gugus fungsi sebelum dan setelah terbentuk nanopartikel kitosan. Hasil analisis PSA diperoleh ukuran partikel sebesar 7270,9 nm. Berdasarkan hal tersebut disimpulkan bahwa sintesis nanopartikel kitosan dapat dilakukan dengan metode gelasi ionik dengan kestabilan selama satu hari. Kata kunci: Gelasi ionik, Kitosan-TPP, Nanopartikel ABSTRACT This experiment aimed to synthesize of chitosan nanoparticles using ionic gelation method. Synthesis stages include: preparation of 0.2% chitosan solution using 5% citric acid, synthesis chitosan nanoparticles with Na-TPP as crosslinker, followed by a test of the stability of the nanoparticles using UV-Vis spectrophotometer. The results of synthesis nanopaticles were characterized using FT-IR, PSA and test water content. The results showed that the nanoparticles of chitosan-TPP suspension remained stable for 1 day storage time and after freeze drying obtained in the form white powder with a water content of 7.25%. Characterization of FT-IR results indicate that the synthesis nanopaticles been formed, it can be seen a shift of the absorption peak of functional groups before and after the formation of chitosan nanoparticles. PSA analysis results obtained that particle size at 7270.9 nm. Based on this it was concluded that synthesis of chitosan nanoparticle can be performed with ionic gelation method with stability during one day. Keywords: Gelasi ionic, Chitosan-TPP, Nanoparticles

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