The Application of Natural Collagen Materials and Tissue Engineering on Repair for Exercise-Induced Meniscus Injury

2013 ◽  
Vol 830 ◽  
pp. 490-494
Author(s):  
Zhi Ping Wang
Keyword(s):  
Tissue Engineering ◽  
Materials Science ◽  
Meniscus Repair ◽  
Practical Application ◽  
Tissue Engineering Scaffolds ◽  
Meniscus Injury ◽  
Meniscus Tissue ◽  
Engineering Problems ◽  
Mechanical Factors ◽  
Exercise Induced

With the development of tissue engineering and materials science, through the research of meniscus tissue engineering to discover novel tissue engineering materials, and further accelerate the research of meniscus tissue engineering, through clinical trials and application of finding appropriate meniscus substitute, which can provide a new mode of treatment for meniscus repair. The focus of the current study including the mechanism of meniscus injury can absorb the natural collagen meniscus tissue engineering scaffolds as feasibility analysis, stress stimulation, meniscus recovery mechanical factors in 4 aspects. Research shows that it has a good application prospect and wider space for meniscus tissue engineering repair of exercise-induced meniscus injury. But in practical application, the meniscus tissue engineering scaffold construction, research on extra cellular matrix composite and its tissue compatibility, repair after tissue engineering meniscus stress stimulation and can withstand the mechanical factors the problem is still the meniscus tissue engineering problems.

The Application of Tissue Engineering and Biological Materials on Exercise-Induced Meniscus Injury

2014 ◽  
Vol 1003 ◽  
pp. 109-112
Author(s):  
Lei Zhang ◽  
Zhi Qiang Zhao ◽  
Xiao Liang Miao ◽  
Hong Mei Zhuang
Keyword(s):  
Tissue Engineering ◽  
Flow Region ◽  
Biological Materials ◽  
Meniscal Injury ◽  
Cell Compatibility ◽  
Synthetic Materials ◽  
Meniscus Tissue ◽  
Meniscal Scaffold ◽  
Scaffold Materials ◽  
Exercise Induced

The development of tissue engineering provides a new way for the repair and reconstruction of meniscal injury. Using this technology to build a functional meniscus in the prevention of complications after meniscectomy has important significance. Because of the blood supply characteristics of the meniscus, meniscal injury caused no blood flow region do not have the ability to heal. The development of tissue engineering provides a new way for the repair and reconstruction of meniscal injury. The repair of meniscal scaffold materials more reports mainly include natural biological materials, synthetic materials, nanomaterials etc. The study of tissue engineering meniscus has achieved initial results, but are in the experimental stage of the scaffold material, there is no an ideal material. Therefore, the search for a good cell compatibility, controllable degradation rate and hot research has certain mechanical strength of scaffold materials is still the meniscus tissue engineering.

scholarly journals Cell-Based Strategies for Meniscus Tissue Engineering

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Wei Niu ◽  
Weimin Guo ◽  
Shufeng Han ◽  
Yun Zhu ◽  
Shuyun Liu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Meniscus Repair ◽  
Cell Type ◽  
Key Factors ◽  
Self Assembling ◽  
Main Cell ◽  
Meniscus Tissue ◽  
Avascular Zone ◽  
Single Cell Type ◽  
The One

Meniscus injuries remain a significant challenge due to the poor healing potential of the inner avascular zone. Following a series of studies and clinical trials, tissue engineering is considered a promising prospect for meniscus repair and regeneration. As one of the key factors in tissue engineering, cells are believed to be highly beneficial in generating bionic meniscus structures to replace injured ones in patients. Therefore, cell-based strategies for meniscus tissue engineering play a fundamental role in meniscal regeneration. According to current studies, the main cell-based strategies for meniscus tissue engineering are single cell type strategies; cell coculture strategies also were applied to meniscus tissue engineering. Likewise, on the one side, the zonal recapitulation strategies based on mimicking meniscal differing cells and internal architectures have received wide attentions. On the other side, cell self-assembling strategies without any scaffolds may be a better way to build a bionic meniscus. In this review, we primarily discuss cell seeds for meniscus tissue engineering and their application strategies. We also discuss recent advances and achievements in meniscus repair experiments that further improve our understanding of meniscus tissue engineering.

Novel tissue engineering scaffolds as wound dressings loaded with Alkannins/Shikonins as active ingredients

2019 ◽  
Author(s):  
AS Arampatzis ◽  
K Theodoridis ◽  
E Aggelidou ◽  
KN Kontogiannopoulos ◽  
I Tsivintzelis ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Wound Dressings ◽  
Active Ingredients ◽  
Tissue Engineering Scaffolds

HYDROXYAPATITE, ALGINATE, AND CHITOSAN FOR BONE SCAFFOLDS: SPECTROSCOPY STUDY

2016 ◽  
Vol 19 (2) ◽  
pp. 93-100
Author(s):  
Lalita El Milla
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Functional Groups ◽  
Bone Growth ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Tissue Engineering Scaffolds ◽  
Hydroxyapatite Powder ◽  
Materials Used

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.

scholarly journals Decellularized Porcine Brain Matrix for Cell Culture and Tissue Engineering Scaffolds

2011 ◽  
Vol 17 (21-22) ◽  
pp. 2583-2592 ◽  
Author(s):  
Jessica A. DeQuach ◽  
Shauna H. Yuan ◽  
Lawrence S.B. Goldstein ◽  
Karen L. Christman
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Tissue Engineering Scaffolds ◽  
Porcine Brain

scholarly journals GAKTpore: Stereological Characterisation Methods for Porous Foams in Biomedical Applications

Materials ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1269
Author(s):  
Gareth Sheppard ◽  
Karl Tassenberg ◽  
Bogdan Nenchev ◽  
Joel Strickland ◽  
Ramy Mesalam ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Biomedical Applications ◽  
Large Scale ◽  
Collagen Scaffold ◽  
Porous Structures ◽  
Tissue Engineering Scaffolds ◽  
Biological Responses ◽  
Sem Micrograph ◽  
Cell Adhesion And Proliferation ◽  
Characterisation Methods

In tissue engineering, scaffolds are a key component that possess a highly elaborate pore structure. Careful characterisation of such porous structures enables the prediction of a variety of large-scale biological responses. In this work, a rapid, efficient, and accurate methodology for 2D bulk porous structure analysis is proposed. The algorithm, “GAKTpore”, creates a morphology map allowing quantification and visualisation of spatial feature variation. The software achieves 99.6% and 99.1% mean accuracy for pore diameter and shape factor identification, respectively. There are two main algorithm novelties within this work: (1) feature-dependant homogeneity map; (2) a new waviness function providing insights into the convexity/concavity of pores, important for understanding the influence on cell adhesion and proliferation. The algorithm is applied to foam structures, providing a full characterisation of a 10 mm diameter SEM micrograph (14,784 × 14,915 px) with 190,249 pores in ~9 min and has elucidated new insights into collagen scaffold formation by relating microstructural formation to the bulk formation environment. This novel porosity characterisation algorithm demonstrates its versatility, where accuracy, repeatability, and time are paramount. Thus, GAKTpore offers enormous potential to optimise and enhance scaffolds within tissue engineering.

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