Synthesis and Properties of Molecularly Imprinted Composite Membranes of Roxithromycin

2009 ◽  
Vol 87-88 ◽  
pp. 80-85
Author(s):  
Jin Yang Yu ◽  
Xiao Ling Hu ◽  
Cui Cui Jiao ◽  
Ya Mei Zhao ◽  
Wei Wei Yang
Keyword(s):  
Cross Sections ◽  
Binding Capacity ◽  
Composite Membranes ◽  
Ethanol Solution ◽  
Differential Scanning Calorimetric ◽  
Separation Mechanism ◽  
Molecularly Imprinted ◽  
Filtration Membranes ◽  
Ultra Filtration ◽  
Imprinted Membrane

Molecularly imprinted composite membranes for selective binding and permeation of roxithromycin were prepared by means of thermal initiated co-polymerization method using polysulfone ultra-filtration membranes as porous supports. Scanning electron microscope was utilized to visualize surface and cross-sections of the membranes to gain more better understanding in the analysis of imprinted layers deposited on PSF support membranes and differential scanning calorimetric was used for determining the thermal stability of the membranes. Static equilibrium binding and recognition properties of the imprinted and non-imprinted membranes to roxithromycin and its analogues in ethanol solution system were tested. The results showed that saturated binding capacity of imprinted membrane to roxithromycin was about 2.24μmol/g, higher than those of its analogues, and the selectivity factors of αRM/EM, αRM/AM and αRM/EE were 1.75, 2.46 and 2.67, respectively. The transport performances of the membranes were evaluated through kinetic filtration experiments. The separation mechanism of the roxithromycin imprinted membrane could be defined as facilitated permeation mechanism.

Enhanced water flux in vertically aligned carbon nanotube arrays and polyethersulfone composite membranes

2014 ◽  
Vol 2 (31) ◽  
pp. 12171-12176 ◽  
Author(s):  
Shaoyun Li ◽  
Gaomin Liao ◽  
Zhipeng Liu ◽  
Yuanyuan Pan ◽  
Qiang Wu ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Water Flux ◽  
Composite Membranes ◽  
Nanotube Arrays ◽  
Nanotube Array ◽  
Filtration Membranes ◽  
Carbon Nanotube Array ◽  
Carbon Nanotube Arrays ◽  
Ultra Filtration ◽  
Vertically Aligned

A vertically aligned carbon nanotube array structure enhances water flux in polyethersulfone ultra-filtration membranes.

Preparation and Recognition Properties of Levodropopizine Molecularly Imprinted Composite Membranes

2011 ◽  
Vol 399-401 ◽  
pp. 355-358 ◽  
Author(s):  
Shan Ping Xu ◽  
Yun Liu ◽  
Li Quan Sun ◽  
Ai Qin Luo
Keyword(s):  
Surface Modification ◽  
Polyvinylidene Fluoride ◽  
Binding Capacity ◽  
Composite Membranes ◽  
Surface Structures ◽  
Scatchard Analysis ◽  
Molecularly Imprinted ◽  
Permeation Studies ◽  
Microfiltration Membranes ◽  
Site Binding

Thin-layer molecularly imprinted composite membranes for selective binding and permeation of levodropopizine were developed via thermal-initiated surface modification of polyvinylidene fluoride microfiltration membranes. ATR-FTIR was used to analyze the surface structures of these membranes. Binding experiments revealed that the saturated binding capacity of MICM was 75.746 umol /g, nearly 3 times higher than that of NICM. Scatchard analysis showed that binding specificity of MICM was a result of multi-site binding to the template. The selective factor of LDPZ and 1-phenylpiperazine was 2.344 in competitive permeation studies. The permeation mechanism of LDPZ imprinted membranes could be inferred as facilitated permeation mechanism.

scholarly journals Molecularly imprinted membrane for transport of urea, creatinine, and vitamin B12 as a hemodialysis candidate membrane

2021 ◽  
Vol 19 (1) ◽  
pp. 806-817
Author(s):  
Muhammad Cholid Djunaidi ◽  
Nabilah Anindita Febriola ◽  
Abdul Haris
Keyword(s):  
Polyethylene Glycol ◽  
Vitamin B12 ◽  
Kidney Function ◽  
Cross Linking ◽  
Vitamin B ◽  
Molecularly Imprinted ◽  
Selective Transport ◽  
Molecularly Imprinted Membrane ◽  
Better Than ◽  
Imprinted Membrane

Abstract High levels of urea and creatinine in the blood are a sign of decreased kidney function. To remove these substances from the blood, hemodialysis which utilizes membranes could be used. In this study, a molecularly imprinted membrane (MIM) was synthesized for the selective transport of urea. The synthesis is initiated with the polymerization of eugenol into polyeugenol and then into polyeugenoxy acetate (PA). The PA is then contacted with urea and then used as the functional polymer in the synthesis of MIM with polysulfone as the membrane base, and polyethylene glycol as the cross-linking agent. The result was later analyzed with FTIR and SEM-EDX. The membrane is then used in the transport of urea, creatinine, and vitamin B12 and then compared with the non-imprinted membrane (NIM) performance. By using UV-Vis spectrophotometry, the results showed that the membrane with 10 h heating variation is able to transport more urea and is more selective than NIM; this proves that the urea template on the MIM enables it to recognize urea molecules better than creatinine and vitamin B12. The order of transport from the best results is urea > creatinine > vitamin B12.

scholarly journals Colorimetric Sensing of Amoxicillin Facilitated by Molecularly Imprinted Polymers

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2221
Author(s):  
Joseph W Lowdon ◽  
Hanne Diliën ◽  
Bart van Grinsven ◽  
Kasper Eersels ◽  
Thomas J. Cleij
Keyword(s):  
Binding Capacity ◽  
Colorimetric Detection ◽  
Bulk Polymerization ◽  
Colorimetric Sensing ◽  
Initial Development ◽  
Molecularly Imprinted ◽  
Synthetic Receptor ◽  
Displacement Assay ◽  
Size And Morphology ◽  
Task Sets

The scope of the presented research orientates itself towards the development of a Molecularly Imprinted Polymer (MIP)-based dye displacement assay for the colorimetric detection of the antibiotic amoxicillin in aqueous medium. With this in mind, the initial development of an MIP capable of such a task sets focus on monolithic bulk polymerization to assess monomer/crosslinker combinations that have potential towards the binding of amoxicillin. The best performing composition (based on specificity and binding capacity) is utilized in the synthesis of MIP particles by emulsion polymerization, yielding particles that prove to be more homogenous in size and morphology compared to that of the crushed monolithic MIP, which is an essential trait when it comes to the accuracy of the resulting assay. The specificity and selectivity of the emulsion MIP proceeds to be highlighted, demonstrating a higher affinity towards amoxicillin compared to other compounds of the aminopenicillin class (ampicillin and cloxacillin). Conversion of the polymeric receptor is then undertaken, identifying a suitable dye for the displacement assay by means of binding experiments with malachite green, crystal violet, and mordant orange. Once identified, the optimal dye is then loaded onto the synthetic receptor, and the displaceability of the dye deduced by means of a dose response experiment. Alongside the sensitivity, the selectivity of the assay is scrutinized against cloxacillin and ampicillin. Yielding a dye displacement assay that can be used (semi-)quantitatively in a rapid manner.

Optimization of Molecularly Imprinted Poly (MAA-co-AM) Composite Membranes for Evaluation of Chlorimuron-Ethyl Herbicide

2013 ◽  
Vol 25 (6) ◽  
pp. 3473-3478
Author(s):  
Xiao-Liu Li ◽  
Zheng-Hao Liu ◽  
Yun-Kai Lv ◽  
Jun-Gang Gao ◽  
Xue-Fei Zhai ◽  
...  
Keyword(s):  
Composite Membranes ◽  
Molecularly Imprinted ◽  
Chlorimuron Ethyl

Facile Fabrication of Flower-Like LLM-105 Three-Dimensional Microstructures

2011 ◽  
Vol 239-242 ◽  
pp. 2942-2945 ◽  
Author(s):  
Jin Chen ◽  
Li Li Wang ◽  
Guang Cheng Yang ◽  
Zhi Qiang Qiao ◽  
Fu De Nie
Keyword(s):  
Cross Sections ◽  
Three Dimensional ◽  
Raw Material ◽  
Differential Scanning Calorimetric ◽  
Recrystallization Process ◽  
X Ray ◽  
Facile Fabrication ◽  
Lower Temperature ◽  
Scanning Electron ◽  
Poor Solvent

Flower-like LLM-105 three-dimensional microstructures, which consisted of LLM-105 microrods with rectangular cross-sections, were prepared via a smiple template- and surfactant-free recrystallization process using [Bmim]CF3SO3as good solvent and water as poor solvent. A tentative mechanism for the growth of the flower-like LLM-105 three-dimensional microstructures was proposed on the basis of the analysis of X-ray powder diffraction (XRD) and scanning electron microscopy (SEM). Comparing with LLM-105 raw material, the thermal decomposition took place at lower temperature and the weight loss has increased for the flower-like three-dimensional microstructures in the differential scanning calorimetric/thermogravimetric (DSC/TG) measurements.

scholarly journals Removal of bisphenol A from aqueous media using a highly selective adsorbent of hybridization cyclodextrin with magnetic molecularly imprinted polymer

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
S. Mamman ◽  
F. B. M. Suah ◽  
M. Raaov ◽  
F. S. Mehamod ◽  
S. Asman ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Molecularly Imprinted Polymer ◽  
Binding Capacity ◽  
Bulk Polymerization ◽  
Resonance Spectroscopy ◽  
Template Molecule ◽  
Order Kinetic ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Magnetic Molecularly Imprinted Polymer

In this study, a unique magnetic molecularly imprinted polymer (MMIP) adsorbent towards bisphenol A (BPA) as a template molecule was developed by bulk polymerization using β-cyclodextrin (β-CD) as a co-monomer with methacrylic acid (MAA) to form MMIP MAA–βCD as a new adsorbent. β-CD was hybridized with MAA to obtain water-compactible imprinting sites for the effective removal of BPA from aqueous samples. Benzoyl peroxide and trimethylolpropane trimethacrylate were used as the initiator and cross-linker, respectively. The adsorbents were characterized by Fourier transform infrared spectroscopy, scanning electronic microscopy, transmission electron microscopy, vibrating sample magnetometer, Brunauer–Emmett–Teller and X-ray diffraction. 1 H nuclear magnetic resonance spectroscopy was used to characterize the MAA–βCD and BPA–MAA–βCD complex. Several parameters influencing the adsorption efficiency of BPA such as adsorbent dosage, pH of sample solution, contact time, initial concentrations and temperature as well as selectivity and reusability study have been evaluated. MMIP MAA–βCD showed significantly higher removal efficiency and selective binding capacity towards BPA compared to MMIP MAA owing to its unique morphology with the presence of β-CD. The kinetics data can be well described by the pseudo second-order kinetic and Freundlich isotherm and Halsey models best fitted the isotherm data. The thermodynamic studies indicated that the adsorption reaction was a spontaneous and exothermic process. Therefore, MMIP based on the hybrid monomer of MAA–βCD shows good potential of a new monomer in molecularly imprinted polymer preparation and can be used as an effective adsorbent for the removal of BPA from aqueous solutions.

Spaceflight effects on beta-adrenoceptor and metabolic properties in rat plantaris

1996 ◽  
Vol 81 (1) ◽  
pp. 152-155 ◽  
Author(s):  
Y. Ohira ◽  
W. Yasui ◽  
F. Kariya ◽  
T. Tanaka ◽  
I. Kitajima ◽  
...  
Keyword(s):  
Cross Sections ◽  
Binding Capacity ◽  
Fiber Type ◽  
Fiber Types ◽  
Sprague Dawley ◽  
Male Adult ◽  
Beta Adrenoceptor ◽  
Mitochondrial Inner Membrane ◽  
Type Composition ◽  
Metabolic Properties

Effects of 14 days of spaceflight on beta-adrenoceptor (beta-AR), mitochondrial enzyme activities, and fiber type composition were studied in plantaris muscles of male adult Sprague-Dawley rats. The beta-AR was analyzed in cross sections by quantitative autoradiography. The maximum binding capacity (Bmax) of beta-AR was significantly lowered (approximately 29%) after flight, but the recovery was not completed within 9 days in 1-G environment. Because the dissociation constant remained unchanged, it is suggested that the changes in the Bmax were caused by the alteration of receptor number. The activities of succinate dehydrogenase (SDH) measured in whole homogenates were subnormal (approximately -24%) in muscles sampled approximately 5 h after flight but they were normalized during 9 days of recovery. The percent composition of fiber types and beta-hydroxyacyl CoA dehydrogenase (HAD) activity did not change significantly due to spaceflight. It is suggested that the spaceflight-induced decrease of the Bmax of beta-AR in plantaris was accompanied by a lowered activity of a mitochondrial inner-membrane enzyme SDH but not a matrix enzyme HAD.

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