Hydroxyapatite Hip Arthroplasty in Osteoporotic Bone: A Study in Female Patients Over the Age of Sixty

2006 ◽  
Vol 309-311 ◽  
pp. 1345-1348
Author(s):  
James M. Buchanan

Uncemented hip arthroplasty is gaining interest. However, it is alleged that uncemented hip implants fail in osteoporotic bone because of early loosening and a higher incidence of periprosthetic fractures. Will Hydroxyapatite Ceramic Coated Hips (HAC) bond on to the osteoporotic bone and continue to function well in this vulnerable group of patients? Post-menopausal women are prone to develop osteoporosis. They are seen too frequently with wrist, hip and spinal crush fractures following minor low impact injuries. These ladies also contribute to the cohort of patents requiring hip arthroplasty for all the usual diagnoses including sub capital fractures. This is a study of HAC hip arthroplasty in female patients over the age of sixty which includes women with osteoporosis.

1976 ◽  
Vol 35 (02) ◽  
pp. 403-414 ◽  
Author(s):  
Terence Davies ◽  
Gillian Fieldhouse ◽  
George P. McNicol

SummaryThe effects on the haemostatic mechanism of oestrogen therapy, given to prevent bone loss in post-menopausal women, have been investigated. Oestriol succinate was given orally to 10 women at a level of 2 mg/day for 1 month and for a further 3 months with incremental increase of 2 mg each month. 6 of the 10 women were subsequently treated with 25 μg/day orally of ethinyl oestradiol. Oestriol succinate therapy resulted in a small increase in the level of factor VII, a decrease in factor VIII concentration and increased sensitivity of platelets to aggregating agents. Ethinyl oestradiol treatment resulted in much more widespread changes with marked increases in coagulation factors VII, VIII, IX and X, decreased levels of antithrombin and dramatic increases in circulating plasminogen levels and euglobulin lysis activity. The data suggested that the nature of oestrogens employed therapeutically is important in determining the qualitative and quantitative effect of oestrogen therapy on components of the haemostatic mechanism.


2016 ◽  
Author(s):  
Antimo Moretti ◽  
Sire Alessandro de ◽  
Dario Calafiore ◽  
Raffaele Gimigliano ◽  
Francesca Gimigliano ◽  
...  

2016 ◽  
Author(s):  
Fernando Blanco-Rodriguez ◽  
Nicole Ellis-Infante ◽  
Victor Lopez-Rivas ◽  
Sherlin May-Kim ◽  
Charlotte Pickett ◽  
...  

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